Both anti-inflammatory and antiviral properties of novel drug candidate ABX464 are mediated by modulation of RNA splicing
Vautrin, Audrey, Manchon, Laurent, Garcel, Aude, Campos, Noëlie, Lapasset, Laure, Laaref, Abdelhamid Mahdi, Bruno, Roman, Gislard, Marie, Dubois, Emeric, Scherrer, Didier, Ehrlich, J Hartmut, Tazi, Jamal
Published in Scientific reports (28.01.2019)
Published in Scientific reports (28.01.2019)
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Journal Article
The Anti-Hiv Candidate Abx464 Dampens Intestinal Inflammation by Triggering Il-22 Production in Activated Macrophages
Chebli, Karim, Papon, Laura, Paul, Conception, Garcel, Aude, Campos, Noëlie, Scherrer, Didier, J Ehrlich, Hartmut, Hahne, Michael, Tazi, Jamal
Published in Scientific reports (07.07.2017)
Published in Scientific reports (07.07.2017)
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Journal Article
Vaccinia virus-induced smallpox postvaccinal encephalitis in case of blood–brain barrier damage
Garcel, Aude, Fauquette, William, Dehouck, Marie-Pierre, Crance, Jean-Marc, Favier, Anne-Laure
Published in Vaccine (08.02.2012)
Published in Vaccine (08.02.2012)
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Sa1238 OBEFAZIMOD REDUCES TOTAL NUMBER OF TUMORS AND HIGH-GRADE ADENOMAS IN A MURINE COLITIS ASSOCIATED COLORECTAL CANCER MODEL
Apolit, Cécile, Lemmers, Bénédicte, Lattanzio, Rossano, Campos, Noélie, Scherrer, Didier, Hahne, Michael, Garcel, Aude
Published in Gastroenterology (New York, N.Y. 1943) (18.05.2024)
Published in Gastroenterology (New York, N.Y. 1943) (18.05.2024)
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Journal Article
Specific and selective induction of miR-124 in immune cells by the quinoline ABX464: a transformative therapy for inflammatory diseases
Tazi, Jamal, Begon-Pescia, Christina, Campos, Noëlie, Apolit, Cécile, Garcel, Aude, Scherrer, Didier
Published in Drug discovery today (01.04.2021)
Published in Drug discovery today (01.04.2021)
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Journal Article
ABX464 (Obefazimod) Upregulates miR-124 to Reduce Proinflammatory Markers in Inflammatory Bowel Diseases
Apolit, Cécile, Campos, Noëlie, Vautrin, Audrey, Begon-Pescia, Christina, Lapasset, Laure, Scherrer, Didier, Gineste, Paul, Ehrlich, Hartmut, Garcel, Aude, Santo, Julien, Tazi, Jamal
Published in Clinical and translational gastroenterology (01.04.2023)
Published in Clinical and translational gastroenterology (01.04.2023)
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Journal Article
Long lasting control of viral rebound with a new drug ABX464 targeting Rev - mediated viral RNA biogenesis
Campos, Noëlie, Myburgh, Renier, Garcel, Aude, Vautrin, Audrey, Lapasset, Laure, Nadal, Erika Schläpfer, Mahuteau-Betzer, Florence, Najman, Romain, Fornarelli, Pauline, Tantale, Katjana, Basyuk, Eugénia, Séveno, Martial, Venables, Julian P, Pau, Bernard, Bertrand, Edouard, Wainberg, Mark A, Speck, Roberto F, Scherrer, Didier, Tazi, Jamal
Published in Retrovirology (09.04.2015)
Published in Retrovirology (09.04.2015)
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Journal Article
miRNA-124 miRNA-124 as a biomarker
SCHERRER DIDIER, CAMPOS NOELIE, MAHUTEAU BETZER FLORENCE, NAJMAN ROMAIN, TAZI JAMAL, GARCEL AUDE
Year of Publication 28.03.2022
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Year of Publication 28.03.2022
Patent
RNA sequencing analysis of activated macrophages treated with the anti-HIV ABX464 in intestinal inflammation
Manchon, Laurent, Chebli, Karim, Papon, Laura, Paul, Conception, Garcel, Aude, Campos, Noëlie, Scherrer, Didier, Ehrlich, Hartmut, Hahne, Michael, Tazi, Jamal
Published in Scientific data (17.10.2017)
Published in Scientific data (17.10.2017)
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Journal Article
A NEW QUINOLINE DERIVATIVE FOR USE IN THE TREATMENT AND PREVENTION OF VIRAL INFECTIONS
SCHERRER DIDIER, CAMPOS NOELIE, NAJMAN ROMAIN, FORNARELLI PAULINE, TAZI JAMAL, GARCEL AUDE, VAUTRIN AUDREY, MAHUTEAU FLORENCE
Year of Publication 27.11.2017
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Year of Publication 27.11.2017
Patent
Phenotypic and genetic diversity of the traditional Lister smallpox vaccine
Garcel, Aude, Perino, Julien, Crance, Jean-Marc, Drillien, Robert, Garin, Daniel, Favier, Anne-Laure
Published in Vaccine (29.01.2009)
Published in Vaccine (29.01.2009)
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바이러스 감염의 치료 또는 예방의 용도를 위한 퀴놀린 유도체
SCHERRER DIDIER, CAMPOS NOELIE, NAJMAN ROMAIN, FORNARELLI PAULINE, TAZI JAMAL, GARCEL AUDE, VAUTRIN AUDREY, MAHUTEAU FLORENCE
Year of Publication 15.11.2017
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Year of Publication 15.11.2017
Patent
Genomic sequence of a clonal isolate of the vaccinia virus Lister strain employed for smallpox vaccination in France and its comparison to other orthopoxviruses
Garcel, Aude, Crance, Jean-Marc, Drillien, Robert, Garin, Daniel, Favier, Anne-Laure
Published in Journal of general virology (01.07.2007)
Published in Journal of general virology (01.07.2007)
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Journal Article
BICYCLIC COMPOUNDS USEFUL FOR TREATING DISEASES CAUSED BY RETROVIRUSES
SCHERRER DIDIER, CAMPOS NOELIE, MAHUTEAU BETZER FLORENCE, NAJMAN ROMAIN, TAZI JAMAL, GARCEL AUDE
Year of Publication 24.03.2016
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Year of Publication 24.03.2016
Patent
MIRNA-124 AS A BIOMARKER
SCHERRER DIDIER, CAMPOS NOELIE, MAHUTEAU BETZER FLORENCE, NAJMAN ROMAIN, TAZI JAMAL, GARCEL AUDE
Year of Publication 01.10.2015
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Year of Publication 01.10.2015
Patent
COMPOUNDS USEFUL FOR TREATING AIDS
SCHERRER DIDIER, CAMPOS NOELIE, NAJMAN ROMAIN, TAZI JAMAL, GARCEL AUDE, MAHUTEAU FLORENCE
Year of Publication 04.04.2014
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Year of Publication 04.04.2014
Patent
COMPOUNDS USEFUL FOR TREATING AIDS
SCHERRER DIDIER, CAMPOS NOELIE, NAJMAN ROMAIN, TAZI JAMAL, GARCEL AUDE, MAHUTEAU FLORENCE
Year of Publication 30.05.2012
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Year of Publication 30.05.2012
Patent
Specific targeting of the F13L protein by ST-246 affects orthopoxvirus production differently
DURAFFOUR, Sophie, VIGNE, Solenne, GARIN, Daniel, ANDREI, Graciela, SNOECK, Robert, VERMEIRE, Kurt, GARCEL, Aude, VANSTREELS, Els, DAELEMANS, Dirk, GUANG YANG, JORDAN, Robert, HRUBY, Dennis E, CRANCE, Jean-Marc
Published in Antiviral therapy (01.01.2008)
Published in Antiviral therapy (01.01.2008)
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