Ang II (Angiotensin II) Conversion to Angiotensin-(1-7) in the Circulation Is POP (Prolyloligopeptidase)-Dependent and ACE2 (Angiotensin-Converting Enzyme 2)-Independent
Serfozo, Peter, Wysocki, Jan, Gulua, Gvantca, Schulze, Arndt, Ye, Minghao, Liu, Pan, Jin, Jing, Bader, Michael, Myöhänen, Timo, García-Horsman, J Arturo, Batlle, Daniel
Published in Hypertension (Dallas, Tex. 1979) (01.01.2020)
Published in Hypertension (Dallas, Tex. 1979) (01.01.2020)
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The expression levels of prolyl oligopeptidase responds not only to neuroinflammation but also to systemic inflammation upon liver failure in rat models and cirrhotic patients
Tenorio-Laranga, Jofre, Montoliu, Carmina, Urios, Amparo, Hernandez-Rabaza, Vicente, Ahabrach, Hanan, García-Horsman, J Arturo, Felipo, Vicente
Published in Journal of neuroinflammation (30.09.2015)
Published in Journal of neuroinflammation (30.09.2015)
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Prolyl oligopeptidase: a rising star on the stage of neuroinflammation research
Penttinen, Anne, Tenorio-Laranga, Jofre, Siikanen, Anssi, Morawski, Markus, Rossner, Steffen, García-Horsman, J Arturo
Published in CNS & neurological disorders drug targets (01.05.2011)
Published in CNS & neurological disorders drug targets (01.05.2011)
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Effect of S-COMT deficiency on behavior and extracellular brain dopamine concentrations in mice
Tammimäki, Anne, Käenmäki, Mikko, Kambur, Oleg, Kulesskaya, Natalia, Keisala, Tiina, Karvonen, Eeva, García-Horsman, J. Arturo, Rauvala, Heikki, Männistö, Pekka T.
Published in Psychopharmacologia (01.09.2010)
Published in Psychopharmacologia (01.09.2010)
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Mechanism of Action of Prolyl Oligopeptidase (PREP) in Degenerative Brain Diseases: Has Peptidase Activity Only a Modulatory Role on the Interactions of PREP with Proteins?
Männistö, Pekka T, García-Horsman, J Arturo
Published in Frontiers in aging neuroscience (14.02.2017)
Published in Frontiers in aging neuroscience (14.02.2017)
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Anticholinergic Drug Use, Serum Anticholinergic Activity, and Adverse Drug Events Among Older People: A Population-Based Study
Lampela, Pasi, Lavikainen, Piia, Garcia-Horsman, J. Arturo, Bell, J. Simon, Huupponen, Risto, Hartikainen, Sirpa
Published in Drugs & aging (01.05.2013)
Published in Drugs & aging (01.05.2013)
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Deficiency of prolyl oligopeptidase in mice disturbs synaptic plasticity and reduces anxiety-like behaviour, body weight, and brain volume
Höfling, Corinna, Kulesskaya, Natalia, Jaako, Külli, Peltonen, Iida, Männistö, Pekka T, Nurmi, Antti, Vartiainen, Nina, Morawski, Markus, Zharkovsky, Alexander, Võikar, Vootele, Roßner, Steffen, García-Horsman, J. Arturo
Published in European neuropsychopharmacology (01.06.2016)
Published in European neuropsychopharmacology (01.06.2016)
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Issues About the Physiological Functions of Prolyl Oligopeptidase Based on Its Discordant Spatial Association With Substrates and Inconsistencies Among mRNA, Protein Levels, and Enzymatic Activity
Myohanen, Timo T, Garcia-Horsman, J. Arturo, Tenorio-Laranga, Jofre, Mannisto, Pekka T
Published in The journal of histochemistry and cytochemistry (01.09.2009)
Published in The journal of histochemistry and cytochemistry (01.09.2009)
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Alteration of prolyl oligopeptidase and activated α-2-macroglobulin in multiple sclerosis subtypes and in the clinically isolated syndrome
Tenorio-Laranga, Jofre, Peltonen, Iida, Keskitalo, Salla, Duran-Torres, Gilberto, Natarajan, Renuka, Männistö, Pekka T., Nurmi, Antti, Vartiainen, Nina, Airas, Laura, Elovaara, Irina, García-Horsman, J. Arturo
Published in Biochemical pharmacology (15.06.2013)
Published in Biochemical pharmacology (15.06.2013)
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Cellular and subcellular distribution of rat brain prolyl oligopeptidase and its association with specific neuronal neurotransmitters
Myöhänen, Timo T., Venäläinen, Jarkko I., Garcia-Horsman, J. Arturo, Piltonen, Marjo, Männistö, Pekka T.
Published in Journal of comparative neurology (1911) (10.04.2008)
Published in Journal of comparative neurology (1911) (10.04.2008)
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Expression and Characterization of Recombinant Human UDP-glucuronosyltransferases (UGTs)
Kurkela, Mika, Garcı́a-Horsman, J. Arturo, Luukkanen, Leena, Mörsky, Saila, Taskinen, Jyrki, Baumann, Marc, Kostiainen, Risto, Hirvonen, Jouni, Finel, Moshe
Published in The Journal of biological chemistry (07.02.2003)
Published in The Journal of biological chemistry (07.02.2003)
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Serotonergic Activation after 2‐Week Intrastriatal Infusion of l‐Dopa and Slow Recovery of Circling in Rats with Unilateral Nigral Lesions
Kääriäinen, Tiina M., García‐Horsman, J. Arturo, Piltonen, Marjo, Huotari, Marko, Männistö, Pekka T.
Published in Basic & clinical pharmacology & toxicology (01.03.2008)
Published in Basic & clinical pharmacology & toxicology (01.03.2008)
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Combination of snap freezing, differential pH two-dimensional reverse-phase high-performance liquid chromatography, and iTRAQ technology for the peptidomic analysis of the effect of prolyl oligopeptidase inhibition in the rat brain
Tenorio-Laranga, Jofre, Valero, M. Luz, Männistö, Pekka T., del Pino, Manuel Sánchez, García-Horsman, J. Arturo
Published in Analytical biochemistry (01.10.2009)
Published in Analytical biochemistry (01.10.2009)
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Binding kinetics and duration of in vivo action of novel prolyl oligopeptidase inhibitors
Venäläinen, Jarkko I., Garcia-Horsman, J. Arturo, Forsberg, Markus M., Jalkanen, Aaro, Wallén, Erik A.A., Jarho, Elina M., Christiaans, Johannes A.M., Gynther, Jukka, Männistö, Pekka T.
Published in Biochemical pharmacology (28.02.2006)
Published in Biochemical pharmacology (28.02.2006)
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