Kinase Inhibitors as Underexplored Antiviral Agents
García-Cárceles, Javier, Caballero, Elena, Gil, Carmen, Martínez, Ana
Published in Journal of medicinal chemistry (27.01.2022)
Published in Journal of medicinal chemistry (27.01.2022)
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Journal Article
A Positive Allosteric Modulator of the Serotonin 5‑HT2C Receptor for Obesity
García-Cárceles, Javier, Decara, Juan M., Vázquez-Villa, Henar, Rodríguez, Ramón, Codesido, Eva, Cruces, Jacobo, Brea, José, Loza, María I., Alén, Francisco, Botta, Joaquin, McCormick, Peter J., Ballesteros, Juan A., Benhamú, Bellinda, Rodríguez de Fonseca, Fernando, López-Rodríguez, María L.
Published in Journal of medicinal chemistry (14.12.2017)
Published in Journal of medicinal chemistry (14.12.2017)
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Journal Article
Discovery of V‑0219: A Small-Molecule Positive Allosteric Modulator of the Glucagon-Like Peptide‑1 Receptor toward Oral Treatment for “Diabesity”
Decara, Juan M, Vázquez-Villa, Henar, Brea, José, Alonso, Mónica, Srivastava, Raj Kamal, Orio, Laura, Alén, Francisco, Suárez, Juan, Baixeras, Elena, García-Cárceles, Javier, Escobar-Peña, Andrea, Lutz, Beat, Rodríguez, Ramón, Codesido, Eva, Garcia-Ladona, F. Javier, Bennett, Teresa A, Ballesteros, Juan A, Cruces, Jacobo, Loza, María I, Benhamú, Bellinda, Rodríguez de Fonseca, Fernando, López-Rodríguez, María L
Published in Journal of medicinal chemistry (14.04.2022)
Published in Journal of medicinal chemistry (14.04.2022)
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Journal Article
Complex Polyheterocycles and the Stereochemical Reassignment of Pileamartine A via Aza-Heck Triggered Aryl C–H Functionalization Cascades
Jones, Benjamin T, García-Cárceles, Javier, Caiger, Lewis, Hazelden, Ian R, Lewis, Richard J, Langer, Thomas, Bower, John F
Published in Journal of the American Chemical Society (29.09.2021)
Published in Journal of the American Chemical Society (29.09.2021)
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Journal Article
A Strategy for the Formal C-N Cross-Coupling of Tertiary Amines
Ledwith, Peter R, Cooney, Madelene L, Bahou, Karim A, García-Cárceles, Javier, Thomson, Joshua, Bower, John
Published in Angewandte Chemie International Edition (22.10.2024)
Published in Angewandte Chemie International Edition (22.10.2024)
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Journal Article
Host-Directed FDA-Approved Drugs with Antiviral Activity against SARS-CoV-2 Identified by Hierarchical In Silico/In Vitro Screening Methods
Ginex, Tiziana, Garaigorta, Urtzi, Ramírez, David, Castro, Victoria, Nozal, Vanesa, Maestro, Inés, García-Cárceles, Javier, Campillo, Nuria E, Martinez, Ana, Gastaminza, Pablo, Gil, Carmen
Published in Pharmaceuticals (Basel, Switzerland) (06.04.2021)
Published in Pharmaceuticals (Basel, Switzerland) (06.04.2021)
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Journal Article
2‑(Fluoromethoxy)-4′‑(S‑methanesulfonimidoyl)-1,1′-biphenyl (UCM-1306), an Orally Bioavailable Positive Allosteric Modulator of the Human Dopamine D1 Receptor for Parkinson’s Disease
García-Cárceles, Javier, Vázquez-Villa, Henar, Brea, José, Ladron de Guevara-Miranda, David, Cincilla, Giovanni, Sánchez-Martínez, Melchor, Sánchez-Merino, Anabel, Algar, Sergio, Teresa de los Frailes, María, Roberts, Richard S., Ballesteros, Juan A., Rodríguez de Fonseca, Fernando, Benhamú, Bellinda, Loza, María I., López-Rodríguez, María L.
Published in Journal of medicinal chemistry (22.09.2022)
Published in Journal of medicinal chemistry (22.09.2022)
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Journal Article
New Synthetic Inhibitors of Fatty Acid Synthase with Anticancer Activity
Turrado, Carlos, Puig, Teresa, García-Cárceles, Javier, Artola, Marta, Benhamú, Bellinda, Ortega-Gutiérrez, Silvia, Relat, Joana, Oliveras, Gloria, Blancafort, Adriana, Haro, Diego, Marrero, Pedro F, Colomer, Ramón, López-Rodríguez, María L
Published in Journal of medicinal chemistry (14.06.2012)
Published in Journal of medicinal chemistry (14.06.2012)
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Journal Article
A Strategy for the Formal C−N Cross‐Coupling of Tertiary Amines
Ledwith, Peter R., Cooney, Madelene L., Bahou, Karim A., García‐Cárceles, Javier, Thomson, Joshua, Bower, John F.
Published in Angewandte Chemie (22.10.2024)
Published in Angewandte Chemie (22.10.2024)
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Journal Article
2-(Fluoromethoxy)-4′-( S -methanesulfonimidoyl)-1,1′-biphenyl (UCM-1306), an Orally Bioavailable Positive Allosteric Modulator of the Human Dopamine D 1 Receptor for Parkinson’s Disease
García-Cárceles, Javier, Vázquez-Villa, Henar, Brea, José, Ladron de Guevara-Miranda, David, Cincilla, Giovanni, Sánchez-Martínez, Melchor, Sánchez-Merino, Anabel, Algar, Sergio, Teresa de los Frailes, María, Roberts, Richard S., Ballesteros, Juan A., Rodríguez de Fonseca, Fernando, Benhamú, Bellinda, Loza, María I., López-Rodríguez, María L.
Published in Journal of medicinal chemistry (22.09.2022)
Published in Journal of medicinal chemistry (22.09.2022)
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Journal Article
A new serotonin 5-HT 6 receptor antagonist with procognitive activity - Importance of a halogen bond interaction to stabilize the binding
González-Vera, Juan A, Medina, Rocío A, Martín-Fontecha, Mar, Gonzalez, Angel, de la Fuente, Tania, Vázquez-Villa, Henar, García-Cárceles, Javier, Botta, Joaquín, McCormick, Peter J, Benhamú, Bellinda, Pardo, Leonardo, López-Rodríguez, María L
Published in Scientific reports (24.01.2017)
Published in Scientific reports (24.01.2017)
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Journal Article
A Positive Allosteric Modulator of the Serotonin 5-HT 2C Receptor for Obesity
García-Cárceles, Javier, Decara, Juan M, Vázquez-Villa, Henar, Rodríguez, Ramón, Codesido, Eva, Cruces, Jacobo, Brea, José, Loza, María I, Alén, Francisco, Botta, Joaquin, McCormick, Peter J, Ballesteros, Juan A, Benhamú, Bellinda, Rodríguez de Fonseca, Fernando, López-Rodríguez, María L
Published in Journal of medicinal chemistry (14.12.2017)
Published in Journal of medicinal chemistry (14.12.2017)
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Journal Article
Essentiality of fatty acid synthase in the 2D to anchorage-independent growth transition in transforming cells
Bueno, Maria J., Jimenez-Renard, Veronica, Samino, Sara, Capellades, Jordi, Junza, Alejandra, López-Rodríguez, María Luz, Garcia-Carceles, Javier, Lopez-Fabuel, Irene, Bolaños, Juan P., Chandel, Navdeep S., Yanes, Oscar, Colomer, Ramon, Quintela-Fandino, Miguel
Published in Nature communications (01.11.2019)
Published in Nature communications (01.11.2019)
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Journal Article
A new serotonin 5-HT6 receptor antagonist with procognitive activity – Importance of a halogen bond interaction to stabilize the binding
González-Vera, Juan A., Medina, Rocío A., Martín-Fontecha, Mar, Gonzalez, Angel, de la Fuente, Tania, Vázquez-Villa, Henar, García-Cárceles, Javier, Botta, Joaquín, McCormick, Peter J., Benhamú, Bellinda, Pardo, Leonardo, López-Rodríguez, María L.
Published in Scientific reports (24.01.2017)
Published in Scientific reports (24.01.2017)
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Journal Article
Host-directed FDA-approved drugs with antiviral activity against SARS-CoV-2 identified by hierarchical in silico/in vitro screening methods
Ginex, Tiziana, Garaigorta, Urtzi, Ramírez, David, Castro, Victoria, Nozal, Vanesa, Maestro, Ines, García-Cárceles, Javier, Campillo, Nuria E, Martinez, Ana, Gastaminza, Pablo, Gil, Carmen
Published in bioRxiv (05.03.2021)
Published in bioRxiv (05.03.2021)
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Paper
NOVEL BIPHENYLSULFOXIMINES AS ALLOSTERIC MODULATORS OF THE DOPAMINE D1 RECEPTOR
Vázquez Villa, María Del Henar, López Rodríguez, María Luz, Benhamú Salama, Bellinda, Loza Garcia, María Isabel, García Cárceles, Javier, Rodriguez De Fonseca, Fernando, Brea Floriani, José Manuel
Year of Publication 26.12.2018
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Year of Publication 26.12.2018
Patent
NOVEL BIPHENYLSULFOXIMINES AS ALLOSTERIC MODULATORS OF THE DOPAMINE D1 RECEPTOR
GARCÍA CÁRCELES, Javier, VAZQUEZ VILLA, María Del Henar, RODRIGUEZ DE FONSECA, Fernando, LÓPEZ RODRÍGUEZ, María Luz, LOZA GARCIA, María Isabel, BENHAMÚ SALAMA, Bellinda, BREA FLORIANI, José Manuel
Year of Publication 27.12.2018
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Year of Publication 27.12.2018
Patent