Inflammation induces endothelial‐to‐mesenchymal transition and promotes vascular calcification through downregulation of BMPR2
Sánchez‐Duffhues, Gonzalo, García de Vinuesa, Amaya, van de Pol, Vera, Geerts, Marlieke E, de Vries, Margreet R, Janson, Stef GT, van Dam, Hans, Lindeman, Jan H., Goumans, Marie‐José, ten Dijke, Peter
Published in The Journal of pathology (01.03.2019)
Published in The Journal of pathology (01.03.2019)
Get full text
Journal Article
TRAF4 Promotes TGF-β Receptor Signaling and Drives Breast Cancer Metastasis
Zhang, Long, Zhou, Fangfang, García de Vinuesa, Amaya, de Kruijf, Esther M., Mesker, Wilma E., Hui, Li, Drabsch, Yvette, Li, Yihao, Bauer, Andreas, Rousseau, Adrien, Sheppard, Kelly-Ann, Mickanin, Craig, Kuppen, Peter J.K., Lu, Chris X., ten Dijke, Peter
Published in Molecular cell (12.09.2013)
Published in Molecular cell (12.09.2013)
Get full text
Journal Article
SLUG Is Expressed in Endothelial Cells Lacking Primary Cilia to Promote Cellular Calcification
Sánchez-Duffhues, Gonzalo, de Vinuesa, Amaya García, Lindeman, Jan H, Mulder-Stapel, Adri, DeRuiter, Marco C, Van Munsteren, Conny, Goumans, Marie-José, Hierck, Beerend P, ten Dijke, Peter
Published in Arteriosclerosis, thrombosis, and vascular biology (01.03.2015)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.03.2015)
Get full text
Journal Article
Disparate phospho-Smad2 levels in advanced type 2 diabetes patients with diabetic nephropathy and early experimental db/db mouse model
Thomsen, Lise Høj, Fog-Tonnesen, Morten, Nielsen Fink, Lisbeth, Norlin, Jenny, García de Vinuesa, Amaya, Hansen, Troels Krarup, de Heer, Emile, ten Dijke, Peter, Rosendahl, Alexander
Published in Renal failure (01.11.2017)
Published in Renal failure (01.11.2017)
Get full text
Journal Article
BMP signaling in vascular biology and dysfunction
García de Vinuesa, Amaya, Abdelilah-Seyfried, Salim, Knaus, Petra, Zwijsen, An, Bailly, Sabine
Published in Cytokine & growth factor reviews (01.02.2016)
Published in Cytokine & growth factor reviews (01.02.2016)
Get full text
Journal Article
Smad2 Phosphorylation in Diabetic Kidney Tubule Epithelial Cells Is Associated with Modulation of Several Transforming Growth Factor-β Family Members
Høj Thomsen, Lise, Fog-Tonnesen, Morten, Nielsen Fink, Lisbeth, Norlin, Jenny, de Vinuesa, Amaya García, Krarup Hansen, Troels, de Heer, Emile, Ten Dijke, Peter, Rosendahl, Alexander
Published in Nephron (2015) (01.01.2017)
Published in Nephron (2015) (01.01.2017)
Get more information
Journal Article
Development of Macrocycle Kinase Inhibitors for ALK2 Using Fibrodysplasia Ossificans Progressiva‐Derived Endothelial Cells
Sánchez‐Duffhues, Gonzalo, Williams, Eleanor, Benderitter, Pascal, Orlova, Valeria, Wijhe, Michiel, Garcia de Vinuesa, Amaya, Kerr, Georgina, Caradec, Josselin, Lodder, Kirsten, Boer, Hetty C., Goumans, Marie‐José, Eekhoff, Elisabeth M W, Morales‐Piga, Antonio, Bachiller‐Corral, Javier, Koolwijk, Pieter, Bullock, Alex N., Hoflack, Jan, Dijke, Peter
Published in JBMR plus (01.11.2019)
Published in JBMR plus (01.11.2019)
Get full text
Journal Article
JNK signalling modulates intestinal homeostasis and tumourigenesis in mice
Sancho, Rocio, Nateri, Abdolrahman S, de Vinuesa, Amaya Garcia, Aguilera, Cristina, Nye, Emma, Spencer-Dene, Bradley, Behrens, Axel
Published in The EMBO journal (08.07.2009)
Published in The EMBO journal (08.07.2009)
Get full text
Journal Article
TGFβ1-induced SMAD2/3 and SMAD1/5 phosphorylation are both ALK5-kinase-dependent in primary chondrocytes and mediated by TAK1 kinase activity
van Caam, Arjan, Madej, Wojciech, Garcia de Vinuesa, Amaya, Goumans, Marie-José, Ten Dijke, Peter, Blaney Davidson, Esmeralda, van der Kraan, Peter
Published in Arthritis research & therapy (31.05.2017)
Published in Arthritis research & therapy (31.05.2017)
Get full text
Journal Article
Cripto favors chondrocyte hypertrophy via TGF‐β SMAD1/5 signaling during development of osteoarthritis
Garcia de Vinuesa, Amaya, Sanchez‐Duffhues, Gonzalo, Blaney‐Davidson, Esmeralda, Caam, Arjan, Lodder, Kirsten, Ramos, Yolande, Kloppenburg, Margreet, Meulenbelt, Ingrid, Kraan, Peter, Goumans, Marie‐José, Dijke, Peter
Published in The Journal of pathology (01.11.2021)
Published in The Journal of pathology (01.11.2021)
Get full text
Journal Article
Opposite effects of anandamide and n-arachidonoyl dopamine in the regulation of prostaglandin E₂ and 8-iso-PGF₂α formation in primary glial cells
Navarrete, Carmen M, Fiebich, Bernd L, de Vinuesa, Amaya García, Hess, Sandra, de Oliveira, Antonio C.P, Candelario-Jalil, Eduardo, Caballero, Francisco J, Calzado, Marco A, Muñoz, Eduardo
Published in Journal of neurochemistry (01.04.2009)
Published in Journal of neurochemistry (01.04.2009)
Get full text
Journal Article
Activin receptor-like kinase 1 as a target for anti-angiogenesis therapy
Hawinkels, Lukas Jac, Garcia de Vinuesa, Amaya, Ten Dijke, Peter
Published in Expert opinion on investigational drugs (01.11.2013)
Published in Expert opinion on investigational drugs (01.11.2013)
Get more information
Journal Article
Activin Receptor-like Kinase 1 Ligand Trap Reduces Microvascular Density and Improves Chemotherapy Efficiency to Various Solid Tumors
Hawinkels, Lukas J A C, de Vinuesa, Amaya Garcia, Paauwe, Madelon, Kruithof-de Julio, Marianna, Wiercinska, Eliza, Pardali, Evangelia, Mezzanotte, Laura, Keereweer, Stijn, Braumuller, Tanya M, Heijkants, Renier C, Jonkers, Jos, Löwik, Clemens W, Goumans, Marie-José, ten Hagen, Timo L, ten Dijke, Peter
Published in Clinical cancer research (01.01.2016)
Published in Clinical cancer research (01.01.2016)
Get full text
Journal Article
Denbinobin inhibits nuclear factor-κB and induces apoptosis via reactive oxygen species generation in human leukemic cells
Sánchez-Duffhues, Gonzalo, Calzado, Marco A., de Vinuesa, Amaya García, Appendino, Giovanni, Fiebich, Bernd L., Loock, Ulich, Lefarth-Risse, Annette, Krohn, Karsten, Muñoz, Eduardo
Published in Biochemical pharmacology (15.04.2009)
Published in Biochemical pharmacology (15.04.2009)
Get full text
Journal Article
Bryostatin-1 synergizes with histone deacetylase inhibitors to reactivate HIV-1 from latency
Pérez, Moisés, de Vinuesa, Amaya García, Sanchez-Duffhues, Gonzalo, Marquez, Nieves, Bellido, M Luz, Muñoz-Fernandez, M Angeles, Moreno, Santiago, Castor, Trevor P, Calzado, Marco A, Muñoz, Eduardo
Published in Current HIV research (01.09.2010)
Published in Current HIV research (01.09.2010)
Get more information
Journal Article
Denbinobin, a naturally occurring 1,4-phenanthrenequinone, inhibits HIV-1 replication through an NF-κB-dependent pathway
Sánchez-Duffhues, Gonzalo, Calzado, Marco A., de Vinuesa, Amaya García, Caballero, Francisco J., Ech-Chahad, Abdellah, Appendino, Giovanni, Krohn, Karsten, Fiebich, Bernd. L., Muñoz, Eduardo
Published in Biochemical pharmacology (15.11.2008)
Published in Biochemical pharmacology (15.11.2008)
Get full text
Journal Article
Endogenous N-acyl-dopamines induce COX-2 expression in brain endothelial cells by stabilizing mRNA through a p38 dependent pathway
Navarrete, Carmen M., Pérez, Moisés, de Vinuesa, Amaya García, Collado, Juan A., Fiebich, Bernd L., Calzado, Marco A., Muñoz, Eduardo
Published in Biochemical pharmacology (15.06.2010)
Published in Biochemical pharmacology (15.06.2010)
Get full text
Journal Article