Vaccinia-related Kinase 1 (VRK1) Is an Upstream Nucleosomal Kinase Required for the Assembly of 53BP1 Foci in Response to Ionizing Radiation-induced DNA Damage
Sanz-García, Marta, Monsalve, Diana M., Sevilla, Ana, Lazo, Pedro A.
Published in The Journal of biological chemistry (06.07.2012)
Published in The Journal of biological chemistry (06.07.2012)
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Journal Article
VRK1 phosphorylates and protects NBS1 from ubiquitination and proteasomal degradation in response to DNA damage
Monsalve, Diana M., Campillo-Marcos, Ignacio, Salzano, Marcella, Sanz-García, Marta, Cantarero, Lara, Lazo, Pedro A.
Published in Biochimica et biophysica acta (01.04.2016)
Published in Biochimica et biophysica acta (01.04.2016)
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Journal Article
VRK1 chromatin kinase phosphorylates H2AX and is required for foci formation induced by DNA damage
Salzano, Marcella, Sanz-García, Marta, Monsalve, Diana M, Moura, David S, Lazo, Pedro A
Published in Epigenetics (04.05.2015)
Published in Epigenetics (04.05.2015)
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Differential inhibitor sensitivity between human kinases VRK1 and VRK2
Vázquez-Cedeira, Marta, Barcia-Sanjurjo, Iria, Sanz-García, Marta, Barcia, Ramiro, Lazo, Pedro A
Published in PloS one (04.08.2011)
Published in PloS one (04.08.2011)
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Journal Article
Modulation of interleukin-1 transcriptional response by the interaction between VRK2 and the JIP1 scaffold protein
Blanco, Sandra, Sanz-García, Marta, Santos, Claudio R, Lazo, Pedro A
Published in PloS one (20.02.2008)
Published in PloS one (20.02.2008)
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Journal Article
VRK1 interacts with p53 forming a basal complex that is activated by UV-induced DNA damage
López-Sánchez, Inmaculada, Valbuena, Alberto, Vázquez-Cedeira, Marta, Khadake, Jyoti, Sanz-García, Marta, Carrillo-Jiménez, Alejandro, Lazo, Pedro A.
Published in FEBS letters (03.03.2014)
Published in FEBS letters (03.03.2014)
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Vaccinia-related kinase 1 (VRK1) confers resistance to DNA-damaging agents in human breast cancer by affecting DNA damage response
Salzano, Marcella, Vázquez-Cedeira, Marta, Sanz-García, Marta, Valbuena, Alberto, Blanco, Sandra, Fernández, Isabel F, Lazo, Pedro A
Published in Oncotarget (15.04.2014)
Published in Oncotarget (15.04.2014)
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The SRY-HMG box gene, SOX4, is a target of gene amplification at chromosome 6p in lung cancer
Medina, Pedro P., Castillo, Sandra D., Blanco, Sandra, Sanz-Garcia, Marta, Largo, Cristina, Alvarez, Sara, Yokota, Jun, Gonzalez-Neira, Ana, Benitez, Javier, Clevers, Hans C., Cigudosa, Juan C., Lazo, Pedro A., Sanchez-Cespedes, Montse
Published in Human molecular genetics (01.04.2009)
Published in Human molecular genetics (01.04.2009)
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Substrate profiling of human vaccinia-related kinases identifies coilin, a Cajal body nuclear protein, as a phosphorylation target with neurological implications
Sanz-García, Marta, Vázquez-Cedeira, Marta, Kellerman, Efrat, Renbaum, Paul, Levy-Lahad, Ephrat, Lazo, Pedro A.
Published in Journal of proteomics (21.12.2011)
Published in Journal of proteomics (21.12.2011)
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Identification of a dominant epitope in human vaccinia-related kinase 1 (VRK1) and detection of different intracellular subpopulations
Valbuena, Alberto, López-Sánchez, Inmaculada, Vega, Francisco M., Sevilla, Ana, Sanz-García, Marta, Blanco, Sandra, Lazo, Pedro A.
Published in Archives of biochemistry and biophysics (01.09.2007)
Published in Archives of biochemistry and biophysics (01.09.2007)
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Immunogenicity of a third dose with mRNA-vaccines in the ChAdOx1-S/BNT162b2 vaccination regimen against SARS-CoV-2 variants
Portolés, Antonio, Campins-Artí, Magdalena, Bertrán, María Jesús, Bermejo, Mercedes, Arribas, José Ramón, López, Andrea, Ascaso-del-Rio, Ana, Arana-Arri, Eunate, Fuentes Camps, Inmaculada, Vilella, Anna, Cascajero, Almudena, García-Morales, María Teresa, Castillo de la Osa, María, Pérez Ingidua, Carla, Lora, David, Jiménez-Santana, Paloma, Pino-Rosa, Silvia, De La Torre-Tarazona, Erick, Calonge, Esther, Belda-Iniesta, Cristóbal, Alcamí, José, Frías, Jesús, Carcas, Antonio J., Díez-Fuertes, Francisco, García, Lucía Díaz, García, Elena Ramírez, Meseguer, Enrique Seco, Candón, Alicia Marín, Elizalde, Mikel Urroz, Rosa, Paula de la, García, Marta Sanz, Crespo, Cristina López, Martínez, Vega Mauleón, de Madariaga Castell, Raquel, Prieto-Pérez, Rocío, Laredo, Leonor, Zhu-Huang, Ouhao, Imaz-Ayo, Natale, García de Vicuña, Aitor, Santorcuato, Ana, Exposito, Iraide, de Benito, Sara, Bustinza, Alazne, Gallego, Mikel, García-Vázquez, Dolores, Belén de la Hoz, Ana, Pérez-Nanclares, Gustavo, Aurrekoetxea, Josu, Urrutia, Ines, Martínez-Salazar, Rosa, Orcajo, Janire, Calvo, Begoña, Corcuera, June, Velasco, Olaia, Aguayo, Anibal, Otero-Romero, Susana, Armadans, Lluis, Borras-Bermejo, Blanca, Uriona, Sonia, Santos, José, Pinós, Laia, Camacho, Lina, Riera, Judith, Sans, Carla, Agustí, Antonia, Blancafort, Carla Aguilar, Serrat, Gisela Gili, Plaza, Aitana, Prius, Anna Feliu, Torrens, Maria Margarita, Torres, Gloria, Calonge, Julia, Alins, Elena Ballarin, Pérez-Esquirol, Eulàlia, Bosch, Lourdes Vendrell, Aldea, Marta, Mellado, Eugènia, Marcos, Ma Ángeles, Tortajada, Marta, Barón-Mira, Lourdes E., Granés, Laura, Lazaar, Sulayman, Herranz, Sara, Malet, Montserrat, Olivé, Victoria, Gómez, Begoña, González, Elisenda, Casals, Cristina, Burunat, Laura, Castelló, Juan José, Fernández, Patricia, Vila, Jordi, Hurtado, Juan Carlos, Jado, Isabel, Fedele, Giovanni, Perea, Concepción, González, Mónica, Murillo, María Ángeles, Balfagón, Pilar, Díaz-Marín, Irene
Published in iScience (20.09.2024)
Published in iScience (20.09.2024)
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A cancer-associated mutation in atypical protein kinase Cι occurs in a substrate-specific recruitment motif
Linch, Mark, Sanz-Garcia, Marta, Soriano, Erika, Zhang, Yixiao, Riou, Philippe, Rosse, Carine, Cameron, Angus, Knowles, Phillip, Purkiss, Andrew, Kjaer, Svend, McDonald, Neil Q, Parker, Peter J
Published in Science signaling (17.09.2013)
Published in Science signaling (17.09.2013)
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Regulation of polarized morphogenesis by protein kinase C iota in oncogenic epithelial spheroids
Linch, Mark, Sanz-Garcia, Marta, Rosse, Carine, Riou, Philippe, Peel, Nick, Madsen, Chris D, Sahai, Erik, Downward, Julian, Khwaja, Asim, Dillon, Christian, Roffey, Jon, Cameron, Angus J M, Parker, Peter J
Published in Carcinogenesis (New York) (01.02.2014)
Published in Carcinogenesis (New York) (01.02.2014)
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