STAT3 serine phosphorylation is required for TLR4 metabolic reprogramming and IL-1β expression
Balic, Jesse J., Albargy, Hassan, Luu, Kevin, Kirby, Francis J., Jayasekara, W. Samantha N., Mansell, Finbar, Garama, Daniel J., De Nardo, Dominic, Baschuk, Nikola, Louis, Cynthia, Humphries, Fiachra, Fitzgerald, Katherine, Latz, Eicke, Gough, Daniel J., Mansell, Ashley
Published in Nature communications (30.07.2020)
Published in Nature communications (30.07.2020)
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Journal Article
Structure and dynamics of the CGRP receptor in apo and peptide-bound forms
Josephs, Tracy M, Belousoff, Matthew J, Liang, Yi-Lynn, Piper, Sarah J, Cao, Jianjun, Garama, Daniel J, Leach, Katie, Gregory, Karen J, Christopoulos, Arthur, Hay, Debbie L, Danev, Radostin, Wootten, Denise, Sexton, Patrick M
Published in Science (American Association for the Advancement of Science) (09.04.2021)
Published in Science (American Association for the Advancement of Science) (09.04.2021)
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Journal Article
MYC drives platinum resistant SCLC that is overcome by the dual PI3K-HDAC inhibitor fimepinostat
Chen, Jasmine, Guanizo, Aleks C, Jakasekara, W Samantha N, Inampudi, Chaitanya, Luong, Quinton, Garama, Daniel J, Alamgeer, Muhammad, Thakur, Nishant, DeVeer, Michael, Ganju, Vinod, Watkins, D Neil, Cain, Jason E, Gough, Daniel J
Published in Journal of experimental & clinical cancer research (26.04.2023)
Published in Journal of experimental & clinical cancer research (26.04.2023)
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Journal Article
Serine-Phosphorylated STAT3 Promotes Tumorigenesis via Modulation of RNA Polymerase Transcriptional Activity
Balic, Jesse J, Garama, Daniel J, Saad, Mohamed I, Yu, Liang, West, Alison C, West, Alice J, Livis, Thaleia, Bhathal, Prithi S, Gough, Daniel J, Jenkins, Brendan J
Published in Cancer research (Chicago, Ill.) (15.10.2019)
Published in Cancer research (Chicago, Ill.) (15.10.2019)
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Journal Article
A Synthetic Lethal Interaction between Glutathione Synthesis and Mitochondrial Reactive Oxygen Species Provides a Tumor-Specific Vulnerability Dependent on STAT3
Garama, Daniel J., Harris, Tiffany J., White, Christine L., Rossello, Fernando J., Abdul-Hay, Maher, Gough, Daniel J., Levy, David E.
Published in Molecular and cellular biology (01.11.2015)
Published in Molecular and cellular biology (01.11.2015)
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Journal Article
A STAT3 protein complex required for mitochondrial mRNA stability and cancer
Fernando, C. Dilanka, Jayasekara, W. Samantha N., Inampudi, Chaitanya, Kohonen-Corish, Maija R.J., Cooper, Wendy A., Beilharz, Traude H., Josephs, Tracy M., Garama, Daniel J., Gough, Daniel J.
Published in Cell reports (Cambridge) (26.09.2023)
Published in Cell reports (Cambridge) (26.09.2023)
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Journal Article
STAT3: a multifaceted oncoprotein
Guanizo, Aleks C., Fernando, Chamira Dilanka, Garama, Daniel J., Gough, Daniel J.
Published in Growth factors (Chur, Switzerland) (04.03.2018)
Published in Growth factors (Chur, Switzerland) (04.03.2018)
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Journal Article
Mitochondrial STAT3: Powering up a potent factor
Garama, Daniel J., White, Christine L., Balic, Jesse J., Gough, Daniel J.
Published in Cytokine (Philadelphia, Pa.) (01.11.2016)
Published in Cytokine (Philadelphia, Pa.) (01.11.2016)
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Journal Article
MED12 and BRD4 cooperate to sustain cancer growth upon loss of mediator kinase
Sooraj, Dhanya, Sun, Claire, Doan, Anh, Garama, Daniel J., Dannappel, Marius V., Zhu, Danxi, Chua, Hui K., Mahara, Sylvia, Wan Hassan, Wan Amir, Tay, Yeng Kwang, Guanizo, Aleks, Croagh, Daniel, Prodanovic, Zdenka, Gough, Daniel J., Wan, Chunhua, Firestein, Ron
Published in Molecular cell (06.01.2022)
Published in Molecular cell (06.01.2022)
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Journal Article
Lineage-restricted neoplasia driven by Myc defaults to small cell lung cancer when combined with loss of p53 and Rb in the airway epithelium
Chen, Jasmine, Guanizo, Aleks, Luong, Quinton, Jayasekara, W. Samantha N., Jayasinghe, Dhilshan, Inampudi, Chaitanya, Szczepny, Anette, Garama, Daniel J., Russell, Prudence A., Ganju, Vinod, Cain, Jason E., Watkins, D. Neil, Gough, Daniel J.
Published in Oncogene (03.01.2022)
Published in Oncogene (03.01.2022)
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Journal Article
The tumor suppressor Hic1 maintains chromosomal stability independent of Tp53
Szczepny, Anette, Carey, Kirstyn, McKenzie, Lisa, Jayasekara, W. Samantha N., Rossello, Fernando, Gonzalez-Rajal, Alvaro, McCaw, Andrew S., Popovski, Dean, Wang, Die, Sadler, Anthony J., Mahar, Annabelle, Russell, Prudence A., Wright, Gavin, McCloy, Rachael A., Garama, Daniel J., Gough, Daniel J., Baylin, Stephen B., Burgess, Andrew, Cain, Jason E., Watkins, D. Neil
Published in Oncogene (01.04.2018)
Published in Oncogene (01.04.2018)
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Journal Article
Mitochondrial DNA haplotypes induce differential patterns of DNA methylation that result in differential chromosomal gene expression patterns
Lee, William T, Sun, Xin, Tsai, Te-Sha, Johnson, Jacqueline L, Gould, Jodee A, Garama, Daniel J, Gough, Daniel J, McKenzie, Matthew, Trounce, Ian A, St. John, Justin C
Published in Cell death discovery (01.01.2017)
Published in Cell death discovery (01.01.2017)
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