Adenosine A2A receptor antagonists: from caffeine to selective non‐xanthines
Jacobson, Kenneth A., Gao, Zhan‐Guo, Matricon, Pierre, Eddy, Matthew T., Carlsson, Jens
Published in British journal of pharmacology (01.07.2022)
Published in British journal of pharmacology (01.07.2022)
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Journal Article
Historical and Current Adenosine Receptor Agonists in Preclinical and Clinical Development
Jacobson, Kenneth A, Tosh, Dilip K, Jain, Shanu, Gao, Zhan-Guo
Published in Frontiers in cellular neuroscience (28.03.2019)
Published in Frontiers in cellular neuroscience (28.03.2019)
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Journal Article
A3 Adenosine Receptors as Modulators of Inflammation: From Medicinal Chemistry to Therapy
Jacobson, Kenneth A., Merighi, Stefania, Varani, Katia, Borea, Pier Andrea, Baraldi, Stefania, Aghazadeh Tabrizi, Mojgan, Romagnoli, Romeo, Baraldi, Pier Giovanni, Ciancetta, Antonella, Tosh, Dilip K., Gao, Zhan‐Guo, Gessi, Stefania
Published in Medicinal research reviews (01.07.2018)
Published in Medicinal research reviews (01.07.2018)
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Journal Article
A2B Adenosine Receptor and Cancer
Gao, Zhan-Guo, Jacobson, Kenneth A.
Published in International journal of molecular sciences (17.10.2019)
Published in International journal of molecular sciences (17.10.2019)
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Journal Article
Structure of an Agonist-Bound Human A2A Adenosine Receptor
FEI XU, HUIXIAN WU, KATRITCH, Vsevolod, GYE WON HAN, JACOBSON, Kenneth A, GAO, Zhan-Guo, CHEREZOV, Vadim, STEVENS, Raymond C
Published in Science (American Association for the Advancement of Science) (15.04.2011)
Published in Science (American Association for the Advancement of Science) (15.04.2011)
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Journal Article
Structural Connection between Activation Microswitch and Allosteric Sodium Site in GPCR Signaling
White, Kate L., Eddy, Matthew T., Gao, Zhan-Guo, Han, Gye Won, Lian, Tiffany, Deary, Alexander, Patel, Nilkanth, Jacobson, Kenneth A., Katritch, Vsevolod, Stevens, Raymond C.
Published in Structure (London) (06.02.2018)
Published in Structure (London) (06.02.2018)
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Journal Article
Two disparate ligand-binding sites in the human P2Y1 receptor
Zhang, Dandan, Gao, Zhan-Guo, Zhang, Kaihua, Kiselev, Evgeny, Crane, Steven, Wang, Jiang, Paoletta, Silvia, Yi, Cuiying, Ma, Limin, Zhang, Wenru, Han, Gye Won, Liu, Hong, Cherezov, Vadim, Katritch, Vsevolod, Jiang, Hualiang, Stevens, Raymond C., Jacobson, Kenneth A., Zhao, Qiang, Wu, Beili
Published in Nature (London) (16.04.2015)
Published in Nature (London) (16.04.2015)
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Journal Article
Allosteric Coupling of Drug Binding and Intracellular Signaling in the A2A Adenosine Receptor
Eddy, Matthew T., Lee, Ming-Yue, Gao, Zhan-Guo, White, Kate L., Didenko, Tatiana, Horst, Reto, Audet, Martin, Stanczak, Pawel, McClary, Kyle M., Han, Gye Won, Jacobson, Kenneth A., Stevens, Raymond C., Wüthrich, Kurt
Published in Cell (11.01.2018)
Published in Cell (11.01.2018)
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Journal Article
On the G protein-coupling selectivity of the native A2B adenosine receptor
Gao, Zhan-Guo, Inoue, Asuka, Jacobson, Kenneth A.
Published in Biochemical pharmacology (01.05.2018)
Published in Biochemical pharmacology (01.05.2018)
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Journal Article
Agonist-bound structure of the human P2Y12 receptor
Zhang, Jin, Zhang, Kaihua, Gao, Zhan-Guo, Paoletta, Silvia, Zhang, Dandan, Han, Gye Won, Li, Tingting, Ma, Limin, Zhang, Wenru, Müller, Christa E., Yang, Huaiyu, Jiang, Hualiang, Cherezov, Vadim, Katritch, Vsevolod, Jacobson, Kenneth A., Stevens, Raymond C., Wu, Beili, Zhao, Qiang
Published in Nature (London) (01.05.2014)
Published in Nature (London) (01.05.2014)
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Journal Article
Ligand design by targeting a binding site water
Matricon, Pierre, Suresh, R. Rama, Gao, Zhan-Guo, Panel, Nicolas, Jacobson, Kenneth A, Carlsson, Jens
Published in Chemical science (Cambridge) (19.11.2020)
Published in Chemical science (Cambridge) (19.11.2020)
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Journal Article
Species dependence of A3 adenosine receptor pharmacology and function
Gao, Zhan-Guo, Auchampach, John A., Jacobson, Kenneth A.
Published in Purinergic signalling (01.09.2023)
Published in Purinergic signalling (01.09.2023)
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Journal Article
Anionic phospholipids control mechanisms of GPCR-G protein recognition
Thakur, Naveen, Ray, Arka P., Sharp, Liam, Jin, Beining, Duong, Alexander, Pour, Niloofar Gopal, Obeng, Samuel, Wijesekara, Anuradha V., Gao, Zhan-Guo, McCurdy, Christopher R., Jacobson, Kenneth A., Lyman, Edward, Eddy, Matthew T.
Published in Nature communications (13.02.2023)
Published in Nature communications (13.02.2023)
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Journal Article
Nucleotides Acting at P2Y Receptors: Connecting Structure and Function
Jacobson, Kenneth A, Paoletta, Silvia, Katritch, Vsevolod, Wu, Beili, Gao, Zhan-Guo, Zhao, Qiang, Stevens, Raymond C, Kiselev, Evgeny
Published in Molecular pharmacology (01.08.2015)
Published in Molecular pharmacology (01.08.2015)
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Journal Article
Novel alendronate-CGS21680 conjugate reduces bone resorption and induces new bone formation in post-menopausal osteoporosis and inflammatory osteolysis mouse models
Larrañaga-Vera, Ane, Toti, Kiran S, Flatow, James S, Haraczy, Alexandra J, Warnick, Eugene, Rao, Harsha, Gao, Zhan-Guo, Sussman, Sarah M, Mediero, Aranzazu, Leucht, Philipp, Jacobson, Kenneth A, Cronstein, Bruce N
Published in Arthritis research & therapy (09.12.2022)
Published in Arthritis research & therapy (09.12.2022)
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Journal Article
Genetic and functional modulation by agonist MRS5698 and allosteric enhancer LUF6000 at the native A3 adenosine receptor in HL-60 cells
Gao, Zhan-Guo, Chen, Weiping, Gao, Ray R., Li, Jonathan, Tosh, Dilip K., Hanover, John A., Jacobson, Kenneth A.
Published in Purinergic signalling (01.10.2024)
Published in Purinergic signalling (01.10.2024)
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