Complement C3 Is Activated in Human AD Brain and Is Required for Neurodegeneration in Mouse Models of Amyloidosis and Tauopathy
Wu, Tiffany, Dejanovic, Borislav, Gandham, Vineela D., Gogineni, Alvin, Edmonds, Rose, Schauer, Stephen, Srinivasan, Karpagam, Huntley, Melanie A., Wang, Yuanyuan, Wang, Tzu-Ming, Hedehus, Maj, Barck, Kai H., Stark, Maya, Ngu, Hai, Foreman, Oded, Meilandt, William J., Elstrott, Justin, Chang, Michael C., Hansen, David V., Carano, Richard A.D., Sheng, Morgan, Hanson, Jesse E.
Published in Cell reports (Cambridge) (20.08.2019)
Published in Cell reports (Cambridge) (20.08.2019)
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Loss of dual leucine zipper kinase signaling is protective in animal models of neurodegenerative disease
Le Pichon, Claire E, Meilandt, William J, Dominguez, Sara, Solanoy, Hilda, Lin, Han, Ngu, Hai, Gogineni, Alvin, Sengupta Ghosh, Arundhati, Jiang, Zhiyu, Lee, Seung-Hye, Maloney, Janice, Gandham, Vineela D, Pozniak, Christine D, Wang, Bei, Lee, Sebum, Siu, Michael, Patel, Snahel, Modrusan, Zora, Liu, Xingrong, Rudhard, York, Baca, Miriam, Gustafson, Amy, Kaminker, Josh, Carano, Richard A D, Huang, Eric J, Foreman, Oded, Weimer, Robby, Scearce-Levie, Kimberly, Lewcock, Joseph W
Published in Science translational medicine (16.08.2017)
Published in Science translational medicine (16.08.2017)
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Antibody-mediated activation of FGFR1 induces FGF23 production and hypophosphatemia
Wu, Ai-Luen, Feng, Bo, Chen, Mark Z, Kolumam, Ganesh, Zavala-Solorio, Jose, Wyatt, Shelby K, Gandham, Vineela D, Carano, Richard A D, Sonoda, Junichiro
Published in PloS one (22.02.2013)
Published in PloS one (22.02.2013)
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Complement C1q-dependent excitatory and inhibitory synapse elimination by astrocytes and microglia in Alzheimer's disease mouse models
Dejanovic, Borislav, Wu, Tiffany, Tsai, Ming-Chi, Graykowski, David, Gandham, Vineela D, Rose, Christopher M, Bakalarski, Corey E, Ngu, Hai, Wang, Yuanyuan, Pandey, Shristi, Rezzonico, Mitchell G, Friedman, Brad A, Edmonds, Rose, De Mazière, Ann, Rakosi-Schmidt, Raphael, Singh, Tarjinder, Klumperman, Judith, Foreman, Oded, Chang, Michael C, Xie, Luke, Sheng, Morgan, Hanson, Jesse E
Published in Nature aging (01.09.2022)
Published in Nature aging (01.09.2022)
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TPL2 kinase activity regulates microglial inflammatory responses and promotes neurodegeneration in tauopathy mice
Wang, Yuanyuan, Wu, Tiffany, Tsai, Ming-Chi, Rezzonico, Mitchell G, Abdel-Haleem, Alyaa M, Xie, Luke, Gandham, Vineela D, Ngu, Hai, Stark, Kimberly, Glock, Caspar, Xu, Daqi, Foreman, Oded, Friedman, Brad A, Sheng, Morgan, Hanson, Jesse E
Published in eLife (09.08.2023)
Published in eLife (09.08.2023)
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Trem2 restrains the enhancement of tau accumulation and neurodegeneration by β-amyloid pathology
Lee, Seung-Hye, Meilandt, William J., Xie, Luke, Gandham, Vineela D., Ngu, Hai, Barck, Kai H., Rezzonico, Mitchell G., Imperio, Jose, Lalehzadeh, Guita, Huntley, Melanie A., Stark, Kimberly L., Foreman, Oded, Carano, Richard A.D., Friedman, Brad A., Sheng, Morgan, Easton, Amy, Bohlen, Christopher J., Hansen, David V.
Published in Neuron (Cambridge, Mass.) (21.04.2021)
Published in Neuron (Cambridge, Mass.) (21.04.2021)
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CYLD Inhibits Melanoma Growth and Progression through Suppression of the JNK/AP-1 and β1-Integrin Signaling Pathways
Ke, Hengning, Augustine, Christina K., Gandham, Vineela D., Jin, Jane Y., Tyler, Douglas S., Akiyama, Steven K., Hall, Russell P., Zhang, Jennifer Y.
Published in Journal of investigative dermatology (2013)
Published in Journal of investigative dermatology (2013)
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Sustained Brown Fat Stimulation and Insulin Sensitization by a Humanized Bispecific Antibody Agonist for Fibroblast Growth Factor Receptor 1/βKlotho Complex
Kolumam, Ganesh, Chen, Mark Z., Tong, Raymond, Zavala-Solorio, Jose, Kates, Lance, van Bruggen, Nicholas, Ross, Jed, Wyatt, Shelby K., Gandham, Vineela D., Carano, Richard A.D., Dunshee, Diana Ronai, Wu, Ai-Luen, Haley, Benjamin, Anderson, Keith, Warming, Søren, Rairdan, Xin Y., Lewin-Koh, Nicholas, Zhang, Yingnan, Gutierrez, Johnny, Baruch, Amos, Gelzleichter, Thomas R., Stevens, Dale, Rajan, Sharmila, Bainbridge, Travis W., Vernes, Jean-Michel, Meng, Y. Gloria, Ziai, James, Soriano, Robert H., Brauer, Matthew J., Chen, Yongmei, Stawicki, Scott, Kim, Hok Seon, Comps-Agrar, Laëtitia, Luis, Elizabeth, Spiess, Christoph, Wu, Yan, Ernst, James A., McGuinness, Owen P., Peterson, Andrew S., Sonoda, Junichiro
Published in EBioMedicine (01.07.2015)
Published in EBioMedicine (01.07.2015)
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CYLD Inhibits Melanoma Growth and Progression through Suppression of the JNK/AP-1 and [beta]1-Integrin Signaling Pathways
Ke, Hengning, Augustine, Christina K, Gandham, Vineela D, Jin, Jane Y, Tyler, Douglas S, Akiyama, Steven K, Hall, Russell P, Zhang, Jennifer Y
Published in Journal of investigative dermatology (01.01.2013)
Published in Journal of investigative dermatology (01.01.2013)
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Journal Article
TPL2 kinase activity regulates microglial inflammatory responses and promotes neurodegeneration in tauopathy mice
Wang, Yuanyuan, Wu, Tiffany, Ming-Chi Tsai, Rezzonico, Mitchell G, Abdel-Haleem, Alyaa M, Xie, Luke, Gandham, Vineela D, Ngu, Hai, Stark, Kimberly, Glock, Caspar, Xu, Daqi, eman, Oded, Friedman, Brad A, Morgan, Sheng, Hanson, Jesse E
Published in bioRxiv (17.10.2022)
Published in bioRxiv (17.10.2022)
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