Broad-Spectrum In Vitro Activity of N α-Aroyl- N -Aryl-Phenylalanine Amides against Non-Tuberculous Mycobacteria and Comparative Analysis of RNA Polymerases
Lang, Markus, Ganapathy, Uday S, Abdelaziz, Rana, Dick, Thomas, Richter, Adrian
Published in Antibiotics (Basel) (28.04.2024)
Published in Antibiotics (Basel) (28.04.2024)
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Journal Article
Blocking ADP-ribosylation expands the anti-mycobacterial spectrum of rifamycins
Ganapathy, Uday S, Lan, Tian, Dartois, Véronique, Aldrich, Courtney C, Dick, Thomas
Published in Microbiology spectrum (01.10.2023)
Published in Microbiology spectrum (01.10.2023)
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Journal Article
In Vitro Profiling of the Synthetic RNA Polymerase Inhibitor MMV688845 against Mycobacterium abscessus
Mann, Lea, Ganapathy, Uday S, Abdelaziz, Rana, Lang, Markus, Zimmerman, Matthew D, Dartois, Véronique, Dick, Thomas, Richter, Adrian
Published in Microbiology spectrum (21.12.2022)
Published in Microbiology spectrum (21.12.2022)
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Journal Article
Epetraborole Is Active against Mycobacterium abscessus
Ganapathy, Uday S, Gengenbacher, Martin, Dick, Thomas
Published in Antimicrobial agents and chemotherapy (17.09.2021)
Published in Antimicrobial agents and chemotherapy (17.09.2021)
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Journal Article
Repositioning rifamycins for Mycobacterium abscessus lung disease
Ganapathy, Uday S., Dartois, Véronique, Dick, Thomas
Published in Expert opinion on drug discovery (02.09.2019)
Published in Expert opinion on drug discovery (02.09.2019)
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Journal Article
TBAJ-876, a 3,5-Dialkoxypyridine Analogue of Bedaquiline, Is Active against Mycobacterium abscessus
Sarathy, Jickky Palmae, Ganapathy, Uday S, Zimmerman, Matthew D, Dartois, Véronique, Gengenbacher, Martin, Dick, Thomas
Published in Antimicrobial agents and chemotherapy (24.03.2020)
Published in Antimicrobial agents and chemotherapy (24.03.2020)
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Journal Article
Synthesis and in vitro Metabolic Stability of Sterically Shielded Antimycobacterial Phenylalanine Amides
Lang, Markus, Ganapathy, Uday S., Mann, Lea, Seidel, Rüdiger W., Goddard, Richard, Erdmann, Frank, Dick, Thomas, Richter, Adrian
Published in ChemMedChem (15.03.2024)
Published in ChemMedChem (15.03.2024)
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Journal Article
ADP-ribosylation-resistant rifabutin analogs show improved bactericidal activity against drug-tolerant M. abscessus in caseum surrogate
Xie, Min, Ganapathy, Uday S, Lan, Tian, Osiecki, Paulina, Sarathy, Jansy P, Dartois, Véronique, Aldrich, Courtney C, Dick, Thomas
Published in Antimicrobial agents and chemotherapy (19.09.2023)
Published in Antimicrobial agents and chemotherapy (19.09.2023)
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Journal Article
Activity of Oral Tebipenem-Avibactam in a Mouse Model of Mycobacterium abscessus Lung Infection
Negatu, Dereje A, González Del Río, Rubén, Cacho-Izquierdo, Mónica, Barros-Aguirre, David, Lelievre, Joël, Rullas, Joaquín, Casado, Patricia, Ganapathy, Uday S, Zimmerman, Matthew D, Gengenbacher, Martin, Dartois, Véronique, Dick, Thomas
Published in Antimicrobial agents and chemotherapy (16.02.2023)
Published in Antimicrobial agents and chemotherapy (16.02.2023)
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Journal Article
A Leucyl-tRNA Synthetase Inhibitor with Broad-Spectrum Antimycobacterial Activity
Ganapathy, Uday S, González del Rio, Rubén, Cacho-Izquierdo, Mónica, Ortega, Fátima, Lelièvre, Joël, Barros-Aguirre, David, Lindman, Marissa, Dartois, Véronique, Gengenbacher, Martin, Dick, Thomas
Published in Antimicrobial agents and chemotherapy (19.04.2021)
Published in Antimicrobial agents and chemotherapy (19.04.2021)
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Journal Article
Redesign of Rifamycin Antibiotics to Overcome ADP‐Ribosylation‐Mediated Resistance
Lan, Tian, Ganapathy, Uday S., Sharma, Sachin, Ahn, Yong‐Mo, Zimmerman, Matthew, Molodtsov, Vadim, Hegde, Pooja, Gengenbacher, Martin, Ebright, Richard H., Dartois, Véronique, Freundlich, Joel S., Dick, Thomas, Aldrich, Courtney C.
Published in Angewandte Chemie International Edition (07.11.2022)
Published in Angewandte Chemie International Edition (07.11.2022)
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Journal Article
Synthesis and Characterization of Phenylalanine Amides Active against Mycobacterium abscessus and Other Mycobacteria
Lang, Markus, Ganapathy, Uday S., Mann, Lea, Abdelaziz, Rana, Seidel, Rüdiger W., Goddard, Richard, Sequenzia, Ilaria, Hoenke, Sophie, Schulze, Philipp, Aragaw, Wassihun Wedajo, Csuk, René, Dick, Thomas, Richter, Adrian
Published in Journal of medicinal chemistry (13.04.2023)
Published in Journal of medicinal chemistry (13.04.2023)
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Journal Article
A Mycobacterium tuberculosis NBTI DNA Gyrase Inhibitor Is Active against Mycobacterium abscessus
Ganapathy, Uday S, Del Río, Rubén González, Cacho-Izquierdo, Mónica, Ortega, Fátima, Lelièvre, Joël, Barros-Aguirre, David, Aragaw, Wassihun Wedajo, Zimmerman, Matthew D, Lindman, Marissa, Dartois, Véronique, Gengenbacher, Martin, Dick, Thomas
Published in Antimicrobial agents and chemotherapy (17.11.2021)
Published in Antimicrobial agents and chemotherapy (17.11.2021)
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Journal Article
Blocking Bacterial Naphthohydroquinone Oxidation and ADP-Ribosylation Improves Activity of Rifamycins against Mycobacterium abscessus
Ganapathy, Uday S, Lan, Tian, Krastel, Philipp, Lindman, Marissa, Zimmerman, Matthew D, Ho, HsinPin, Sarathy, Jansy P, Evans, Joanna C, Dartois, Véronique, Aldrich, Courtney C, Dick, Thomas
Published in Antimicrobial agents and chemotherapy (17.08.2021)
Published in Antimicrobial agents and chemotherapy (17.08.2021)
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Journal Article
Redesign of Rifamycin Antibiotics to Overcome ADP‐Ribosylation‐Mediated Resistance
Lan, Tian, Ganapathy, Uday S., Sharma, Sachin, Ahn, Yong‐Mo, Zimmerman, Matthew, Molodtsov, Vadim, Hegde, Pooja, Gengenbacher, Martin, Ebright, Richard H., Dartois, Véronique, Freundlich, Joel S., Dick, Thomas, Aldrich, Courtney C.
Published in Angewandte Chemie (07.11.2022)
Published in Angewandte Chemie (07.11.2022)
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Journal Article
Compartment-Specific Labeling of Bacterial Periplasmic Proteins by Peroxidase-Mediated Biotinylation
Ganapathy, Uday S., Bai, Lu, Wei, Linpeng, Eckartt, Kathryn A., Lett, Clarissa M., Previti, Mary L., Carrico, Isaac S., Seeliger, Jessica C.
Published in ACS infectious diseases (08.06.2018)
Published in ACS infectious diseases (08.06.2018)
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Journal Article
Correction to Compartment-Specific Labeling of Bacterial Periplasmic Proteins by Peroxidase-Mediated Biotinylation
Ganapathy, Uday S, Bai, Lu, Wei, Linpeng, Eckartt, Kathryn A, Lett, Clarissa M, Previti, Mary L, Carrico, Isaac S, Seeliger, Jessica C
Published in ACS infectious diseases (13.07.2018)
Published in ACS infectious diseases (13.07.2018)
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Journal Article
A Leucyl-tRNA Synthetase Inhibitor with Broad-Spectrum Anti-Mycobacterial Activity
Ganapathy, Uday S, Del Rio, Rubén González, Cacho-Izquierdo, Mónica, Ortega, Fátima, Lelièvre, Joël, Barros-Aguirre, David, Lindman, Marissa, Dartois, Véronique, Gengenbacher, Martin, Dick, Thomas
Published in Antimicrobial agents and chemotherapy (01.05.2023)
Published in Antimicrobial agents and chemotherapy (01.05.2023)
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Journal Article