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Published in Nature cell biology (01.02.2019)
Published in Nature cell biology (01.02.2019)
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PRMT5-mediated arginine methylation activates AKT kinase to govern tumorigenesis
Yin, Shasha, Liu, Liu, Brobbey, Charles, Palanisamy, Viswanathan, Ball, Lauren E, Olsen, Shaun K, Ostrowski, Michael C, Gan, Wenjian
Published in Nature communications (08.06.2021)
Published in Nature communications (08.06.2021)
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The Roles of Post-Translational Modifications on mTOR Signaling
Yin, Shasha, Liu, Liu, Gan, Wenjian
Published in International journal of molecular sciences (11.02.2021)
Published in International journal of molecular sciences (11.02.2021)
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R-loop-mediated genomic instability is caused by impairment of replication fork progression
Gan, Wenjian, Guan, Zhishuang, Liu, Jie, Gui, Ting, Shen, Keng, Manley, James L, Li, Xialu
Published in Genes & development (01.10.2011)
Published in Genes & development (01.10.2011)
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K63-linked polyubiquitin chains bind to DNA to facilitate DNA damage repair
Liu, Pengda, Gan, Wenjian, Su, Siyuan, Hauenstein, Arthur V, Fu, Tian-Min, Brasher, Bradley, Schwerdtfeger, Carsten, Liang, Anthony C, Xu, Ming, Wei, Wenyi
Published in Science signaling (05.06.2018)
Published in Science signaling (05.06.2018)
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PtdIns(3,4,5)P3-Dependent Activation of the mTORC2 Kinase Complex
Liu, Pengda, Gan, Wenjian, Chin, Y Rebecca, Ogura, Kohei, Guo, Jianping, Zhang, Jinfang, Wang, Bin, Blenis, John, Cantley, Lewis C, Toker, Alex, Su, Bing, Wei, Wenyi
Published in Cancer discovery (01.11.2015)
Published in Cancer discovery (01.11.2015)
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Genetic fusions favor tumorigenesis through degron loss in oncogenes
Liu, Jing, Tokheim, Collin, Lee, Jonathan D, Gan, Wenjian, North, Brian J, Liu, X Shirley, Pandolfi, Pier Paolo, Wei, Wenyi
Published in Nature communications (18.11.2021)
Published in Nature communications (18.11.2021)
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SPOP Promotes Ubiquitination and Degradation of the ERG Oncoprotein to Suppress Prostate Cancer Progression
Gan, Wenjian, Dai, Xiangpeng, Lunardi, Andrea, Li, Zhen, Inuzuka, Hiroyuki, Liu, Pengda, Varmeh, Shoreh, Zhang, Jinfang, Cheng, Liang, Sun, Yin, Asara, John M., Beck, Andrew H., Huang, Jiaoti, Pandolfi, Pier Paolo, Wei, Wenyi
Published in Molecular cell (17.09.2015)
Published in Molecular cell (17.09.2015)
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Convolutional MLP orthogonal fusion of multiscale features for visual place recognition
Gan, Wenjian, Zhou, Yang, Hu, Xiaofei, Zhao, Luying, Huang, Gaoshuang, Zhang, Chenglong
Published in Scientific reports (23.05.2024)
Published in Scientific reports (23.05.2024)
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Prostate cancer-associated SPOP mutations confer resistance to BET inhibitors through stabilization of BRD4
Dai, Xiangpeng, Gan, Wenjian, Li, Xiaoning, Wang, Shangqian, Zhang, Wei, Huang, Ling, Liu, Shengwu, Zhong, Qing, Guo, Jianping, Zhang, Jinfang, Chen, Ting, Shimizu, Kouhei, Beca, Francisco, Blattner, Mirjam, Vasudevan, Divya, Buckley, Dennis L, Qi, Jun, Buser, Lorenz, Liu, Pengda, Inuzuka, Hiroyuki, Beck, Andrew H, Wang, Liewei, Wild, Peter J, Garraway, Levi A, Rubin, Mark A, Barbieri, Christopher E, Wong, Kwok-Kin, Muthuswamy, Senthil K, Huang, Jiaoti, Chen, Yu, Bradner, James E, Wei, Wenyi
Published in Nature medicine (01.09.2017)
Published in Nature medicine (01.09.2017)
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LATS suppresses mTORC1 activity to directly coordinate Hippo and mTORC1 pathways in growth control
Gan, Wenjian, Dai, Xiaoming, Dai, Xiangpeng, Xie, Jun, Yin, Shasha, Zhu, Junjie, Wang, Chen, Liu, Yuchen, Guo, Jianping, Wang, Min, Liu, Jing, Hu, Jia, Quinton, Ryan J, Ganem, Neil J, Liu, Pengda, Asara, John M, Pandolfi, Pier Paolo, Yang, Yingzi, He, Zhigang, Gao, Guangping, Wei, Wenyi
Published in Nature cell biology (01.02.2020)
Published in Nature cell biology (01.02.2020)
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The Role of Protein Arginine Methyltransferases in DNA Damage Response
Brobbey, Charles, Liu, Liu, Yin, Shasha, Gan, Wenjian
Published in International journal of molecular sciences (29.08.2022)
Published in International journal of molecular sciences (29.08.2022)
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pVHL suppresses kinase activity of Akt in a proline-hydroxylation-dependent manner
Guo, Jianping, Chakraborty, Abhishek A., Liu, Pengda, Gan, Wenjian, Zheng, Xingnan, Inuzuka, Hiroyuki, Wang, Bin, Zhang, Jinfang, Zhang, Linli, Yuan, Min, Novak, Jesse, Cheng, Jin Q., Toker, Alex, Signoretti, Sabina, Zhang, Qing, Asara, John M., Kaelin, William G., Wei, Wenyi
Published in Science (American Association for the Advancement of Science) (26.08.2016)
Published in Science (American Association for the Advancement of Science) (26.08.2016)
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Cell-cycle-regulated activation of Akt kinase by phosphorylation at its carboxyl terminus
Liu, Pengda, Begley, Michael, Michowski, Wojciech, Inuzuka, Hiroyuki, Ginzberg, Miriam, Gao, Daming, Tsou, Peiling, Gan, Wenjian, Papa, Antonella, Kim, Byeong Mo, Wan, Lixin, Singh, Amrik, Zhai, Bo, Yuan, Min, Wang, Zhiwei, Gygi, Steven P, Lee, Tae Ho, Lu, Kun-Ping, Toker, Alex, Pandolfi, Pier Paolo, Asara, John M, Kirschner, Marc W, Sicinski, Piotr, Cantley, Lewis, Wei, Wenyi
Published in Nature (London) (24.04.2014)
Published in Nature (London) (24.04.2014)
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PTEN Methylation by NSD2 Controls Cellular Sensitivity to DNA Damage
Zhang, Jinfang, Lee, Yu-Ru, Dang, Fabin, Gan, Wenjian, Menon, Archita Venugopal, Katon, Jesse M, Hsu, Chih-Hung, Asara, John M, Tibarewal, Priyanka, Leslie, Nicholas R, Shi, Yang, Pandolfi, Pier Paolo, Wei, Wenyi
Published in Cancer discovery (01.09.2019)
Published in Cancer discovery (01.09.2019)
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Inhibition of Rb Phosphorylation Leads to mTORC2-Mediated Activation of Akt
Zhang, Jinfang, Xu, Kai, Liu, Pengda, Geng, Yan, Wang, Bin, Gan, Wenjian, Guo, Jianping, Wu, Fei, Chin, Y. Rebecca, Berrios, Christian, Lien, Evan C., Toker, Alex, DeCaprio, James A., Sicinski, Piotr, Wei, Wenyi
Published in Molecular cell (16.06.2016)
Published in Molecular cell (16.06.2016)
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CDK5-PRMT1-WDR24 signaling cascade promotes mTORC1 signaling and tumor growth
Yin, Shasha, Liu, Liu, Ball, Lauren E., Wang, Yalong, Bedford, Mark T., Duncan, Stephen A., Wang, Haizhen, Gan, Wenjian
Published in Cell reports (Cambridge) (25.04.2023)
Published in Cell reports (Cambridge) (25.04.2023)
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Autophagy dictates sensitivity to PRMT5 inhibitor in breast cancer
Brobbey, Charles, Yin, Shasha, Liu, Liu, Ball, Lauren E, Howe, Philip H, Delaney, Joe R, Gan, Wenjian
Published in Scientific reports (03.07.2023)
Published in Scientific reports (03.07.2023)
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