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Notta, Faiyaz, Zandi, Sasan, Takayama, Naoya, Dobson, Stephanie, Gan, Olga I., Wilson, Gavin, Kaufmann, Kerstin B., McLeod, Jessica, Laurenti, Elisa, Dunant, Cyrille F., McPherson, John D., Stein, Lincoln D., Dror, Yigal, Dick, John E.
Published in Science (American Association for the Advancement of Science) (08.01.2016)
Published in Science (American Association for the Advancement of Science) (08.01.2016)
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TFEB-mediated endolysosomal activity controls human hematopoietic stem cell fate
García-Prat, Laura, Kaufmann, Kerstin B., Schneiter, Florin, Voisin, Veronique, Murison, Alex, Chen, Jocelyn, Chan-Seng-Yue, Michelle, Gan, Olga I., McLeod, Jessica L., Smith, Sabrina A., Shoong, Michelle C., Parris, Darrien, Pan, Kristele, Zeng, Andy G.X., Krivdova, Gabriela, Gupta, Kinam, Takayanagi, Shin-Ichiro, Wagenblast, Elvin, Wang, Weijia, Lupien, Mathieu, Schroeder, Timm, Xie, Stephanie Z., Dick, John E.
Published in Cell stem cell (07.10.2021)
Published in Cell stem cell (07.10.2021)
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The Transition from Quiescent to Activated States in Human Hematopoietic Stem Cells Is Governed by Dynamic 3D Genome Reorganization
Takayama, Naoya, Murison, Alex, Takayanagi, Shin-ichiro, Arlidge, Christopher, Zhou, Stanley, Garcia-Prat, Laura, Chan-Seng-Yue, Michelle, Zandi, Sasan, Gan, Olga I., Boutzen, Héléna, Kaufmann, Kerstin B., Trotman-Grant, Aaron, Schoof, Erwin, Kron, Ken, Díaz, Noelia, Lee, John J.Y., Medina, Tiago, De Carvalho, Daniel D., Taylor, Michael D., Vaquerizas, Juan M., Xie, Stephanie Z., Dick, John E., Lupien, Mathieu
Published in Cell stem cell (04.03.2021)
Published in Cell stem cell (04.03.2021)
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Variable Clonal Repopulation Dynamics Influence Chemotherapy Response in Colorectal Cancer
Kreso, Antonija, O'Brien, Catherine A., van Galen, Peter, Gan, Olga I., Notta, Faiyaz, Brown, Andrew M. K., Ng, Karen, Ma, Jing, Wienholds, Erno, Dunant, Cyrille, Pollett, Aaron, Gallinger, Steven, McPherson, John, Mullighan, Charles G., Shibata, Darryl, Dick, John E.
Published in Science (American Association for the Advancement of Science) (01.02.2013)
Published in Science (American Association for the Advancement of Science) (01.02.2013)
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Mapping the cellular origin and early evolution of leukemia in Down syndrome
Wagenblast, Elvin, Araújo, Joana, Gan, Olga I, Cutting, Sarah K, Murison, Alex, Krivdova, Gabriela, Azkanaz, Maria, McLeod, Jessica L, Smith, Sabrina A, Gratton, Blaise A, Marhon, Sajid A, Gabra, Martino, Medeiros, Jessie J F, Manteghi, Sanaz, Chen, Jian, Chan-Seng-Yue, Michelle, Garcia-Prat, Laura, Salmena, Leonardo, De Carvalho, Daniel D, Abelson, Sagi, Abdelhaleem, Mohamed, Chong, Karen, Roifman, Maian, Shannon, Patrick, Wang, Jean C Y, Hitzler, Johann K, Chitayat, David, Dick, John E, Lechman, Eric R
Published in Science (American Association for the Advancement of Science) (09.07.2021)
Published in Science (American Association for the Advancement of Science) (09.07.2021)
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Functional profiling of single CRISPR/Cas9-edited human long-term hematopoietic stem cells
Wagenblast, Elvin, Azkanaz, Maria, Smith, Sabrina A, Shakib, Lorien, McLeod, Jessica L, Krivdova, Gabriela, Araújo, Joana, Shultz, Leonard D, Gan, Olga I, Dick, John E, Lechman, Eric R
Published in Nature communications (18.10.2019)
Published in Nature communications (18.10.2019)
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Sphingolipid Modulation Activates Proteostasis Programs to Govern Human Hematopoietic Stem Cell Self-Renewal
Xie, Stephanie Z., Garcia-Prat, Laura, Voisin, Veronique, Ferrari, Robin, Gan, Olga I., Wagenblast, Elvin, Kaufmann, Kerstin B., Zeng, Andy G.X., Takayanagi, Shin-ichiro, Patel, Ishita, Lee, Esther K., Jargstorf, Joseph, Holmes, Gareth, Romm, Guy, Pan, Kristele, Shoong, Michelle, Vedi, Aditi, Luberto, Chiara, Minden, Mark D., Bader, Gary D., Laurenti, Elisa, Dick, John E.
Published in Cell stem cell (07.11.2019)
Published in Cell stem cell (07.11.2019)
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Transcriptomic classes of BCR-ABL1 lymphoblastic leukemia
Kim, Jaeseung C, Chan-Seng-Yue, Michelle, Ge, Sabrina, Zeng, Andy G X, Ng, Karen, Gan, Olga I, Garcia-Prat, Laura, Flores-Figueroa, Eugenia, Woo, Tristan, Zhang, Amy Xin Wei, Arruda, Andrea, Chithambaram, Shivapriya, Dobson, Stephanie M, Khoo, Amanda, Khan, Shahbaz, Ibrahimova, Narmin, George, Ann, Tierens, Anne, Hitzler, Johann, Kislinger, Thomas, Dick, John E, McPherson, John D, Minden, Mark D, Notta, Faiyaz
Published in Nature genetics (01.07.2023)
Published in Nature genetics (01.07.2023)
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A Distinctive DNA Damage Response in Human Hematopoietic Stem Cells Reveals an Apoptosis-Independent Role for p53 in Self-Renewal
Milyavsky, Michael, Gan, Olga I., Trottier, Magan, Komosa, Martin, Tabach, Ofer, Notta, Faiyaz, Lechman, Eric, Hermans, Karin G., Eppert, Kolja, Konovalova, Zhanna, Ornatsky, Olga, Domany, Eytan, Meyn, M. Stephen, Dick, John E.
Published in Cell stem cell (06.08.2010)
Published in Cell stem cell (06.08.2010)
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Sphingosine-1-phosphate receptor 3 potentiates inflammatory programs in normal and leukemia stem cells to promote differentiation
Xie, Stephanie Z, Kaufmann, Kerstin B, Wang, Weijia, Chan-Seng-Yue, Michelle, Gan, Olga I, Laurenti, Elisa, Garcia-Prat, Laura, Takayanagi, Shin-Ichiro, Ng, Stanley W K, Xu, ChangJiang, Zeng, Andy G X, Jin, Liqing, McLeod, Jessica, Wagenblast, Elvin, Mitchell, Amanda, Kennedy, James A, Liu, Qiang, Boutzen, Héléna, Kleinau, Melissa, Jargstorf, Joseph, Holmes, Gareth, Zhang, Yang, Voisin, Veronique, Bader, Gary D, Wang, Jean C Y, Hannun, Yusuf A, Luberto, Chiara, Schroeder, Timm, Minden, Mark D, Dick, John E
Published in Blood cancer discovery (01.01.2021)
Published in Blood cancer discovery (01.01.2021)
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Polymorphism in Sirpa modulates engraftment of human hematopoietic stem cells
Mortin-Toth, Steven M, Takenaka, Katsuto, Gan, Olga I, Danska, Jayne S, Prasolava, Tatiana K, Dick, John E, Wang, Jean C Y, Khalouei, Sam
Published in Nature immunology (01.12.2007)
Published in Nature immunology (01.12.2007)
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Relapse-Fated Latent Diagnosis Subclones in Acute B Lineage Leukemia Are Drug Tolerant and Possess Distinct Metabolic Programs
Dobson, Stephanie M, García-Prat, Laura, Vanner, Robert J, Wintersinger, Jeffrey, Waanders, Esmé, Gu, Zhaohui, McLeod, Jessica, Gan, Olga I, Grandal, Ildiko, Payne-Turner, Debbie, Edmonson, Michael N, Ma, Xiaotu, Fan, Yiping, Voisin, Veronique, Chan-Seng-Yue, Michelle, Xie, Stephanie Z, Hosseini, Mohsen, Abelson, Sagi, Gupta, Pankaj, Rusch, Michael, Shao, Ying, Olsen, Scott R, Neale, Geoffrey, Chan, Steven M, Bader, Gary, Easton, John, Guidos, Cynthia J, Danska, Jayne S, Zhang, Jinghui, Minden, Mark D, Morris, Quaid, Mullighan, Charles G, Dick, John E
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Published in Cancer discovery (01.04.2020)
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A latent subset of human hematopoietic stem cells resists regenerative stress to preserve stemness
Kaufmann, Kerstin B, Zeng, Andy G X, Coyaud, Etienne, Garcia-Prat, Laura, Papalexi, Efthymia, Murison, Alex, Laurent, Estelle M N, Chan-Seng-Yue, Michelle, Gan, Olga I, Pan, Kristele, McLeod, Jessica, Boutzen, Héléna, Zandi, Sasan, Takayanagi, Shin-Ichiro, Satija, Rahul, Raught, Brian, Xie, Stephanie Z, Dick, John E
Published in Nature immunology (01.06.2021)
Published in Nature immunology (01.06.2021)
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Identification of the global miR-130a targetome reveals a role for TBL1XR1 in hematopoietic stem cell self-renewal and t(8;21) AML
Krivdova, Gabriela, Voisin, Veronique, Schoof, Erwin M., Marhon, Sajid A., Murison, Alex, McLeod, Jessica L., Gabra, Martino M., Zeng, Andy G.X., Aigner, Stefan, Yee, Brian A., Shishkin, Alexander A., Van Nostrand, Eric L., Hermans, Karin G., Trotman-Grant, Aaron C., Mbong, Nathan, Kennedy, James A., Gan, Olga I., Wagenblast, Elvin, De Carvalho, Daniel D., Salmena, Leonardo, Minden, Mark D., Bader, Gary D., Yeo, Gene W., Dick, John E., Lechman, Eric R.
Published in Cell reports (Cambridge) (08.03.2022)
Published in Cell reports (Cambridge) (08.03.2022)
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KDM6 demethylases integrate DNA repair gene regulation and loss of KDM6A sensitizes human acute myeloid leukemia to PARP and BCL2 inhibition
Boila, Liberalis Debraj, Ghosh, Subhadeep, Bandyopadhyay, Subham K, Jin, Liqing, Murison, Alex, Zeng, Andy G X, Shaikh, Wasim, Bhowmik, Satyaki, Muddineni, Siva Sai Naga Anurag, Biswas, Mayukh, Sinha, Sayantani, Chatterjee, Shankha Subhra, Mbong, Nathan, Gan, Olga I, Bose, Anwesha, Chakraborty, Sayan, Arruda, Andrea, Kennedy, James A, Mitchell, Amanda, Lechman, Eric R, Banerjee, Debasis, Milyavsky, Michael, Minden, Mark D, Dick, John E, Sengupta, Amitava
Published in Leukemia (01.04.2023)
Published in Leukemia (01.04.2023)
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An ERG Enhancer-Based Reporter Identifies Leukemia Cells with Elevated Leukemogenic Potential Driven by ERG-USP9X Feed-Forward Regulation
Aqaqe, Nasma, Yassin, Muhammad, Yassin, Abed Alkader, Ershaid, Nour, Katz-Even, Chen, Zipin-Roitman, Adi, Kugler, Eitan, Lechman, Eric R, Gan, Olga I, Mitchell, Amanda, Dick, John E, Izraeli, Shai, Milyavsky, Michael
Published in Cancer research (Chicago, Ill.) (01.08.2019)
Published in Cancer research (Chicago, Ill.) (01.08.2019)
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Ectopic miR-125a Expression Induces Long-Term Repopulating Stem Cell Capacity in Mouse and Human Hematopoietic Progenitors
Wojtowicz, Edyta E., Lechman, Eric R., Hermans, Karin G., Schoof, Erwin M., Wienholds, Erno, Isserlin, Ruth, van Veelen, Peter A., Broekhuis, Mathilde J.C., Janssen, George M.C., Trotman-Grant, Aaron, Dobson, Stephanie M., Krivdova, Gabriela, Elzinga, Jantje, Kennedy, James, Gan, Olga I., Sinha, Ankit, Ignatchenko, Vladimir, Kislinger, Thomas, Dethmers-Ausema, Bertien, Weersing, Ellen, Alemdehy, Mir Farshid, de Looper, Hans W.J., Bader, Gary D., Ritsema, Martha, Erkeland, Stefan J., Bystrykh, Leonid V., Dick, John E., de Haan, Gerald
Published in Cell stem cell (01.09.2016)
Published in Cell stem cell (01.09.2016)
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Multiomic Profiling of Central Nervous System Leukemia Identifies mRNA Translation as a Therapeutic Target
Vanner, Robert J, Dobson, Stephanie M, Gan, Olga I, McLeod, Jessica, Schoof, Erwin M, Grandal, Ildiko, Wintersinger, Jeff A, Garcia-Prat, Laura, Hosseini, Mohsen, Xie, Stephanie Z, Jin, Liqing, Mbong, Nathan, Voisin, Veronique, Chan-Seng-Yue, Michelle, Kennedy, James A, Waanders, Esmé, Morris, Quaid, Porse, Bo, Chan, Steven M, Guidos, Cynthia J, Danska, Jayne S, Minden, Mark D, Mullighan, Charles G, Dick, John E
Published in Blood cancer discovery (01.01.2022)
Published in Blood cancer discovery (01.01.2022)
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