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Generation of three-dimensional retinal tissue with functional photoreceptors from human iPSCs
Zhong, Xiufeng, Gutierrez, Christian, Xue, Tian, Hampton, Christopher, Vergara, M. Natalia, Cao, Li-Hui, Peters, Ann, Park, Tea Soon, Zambidis, Elias T., Meyer, Jason S., Gamm, David M., Yau, King-Wai, Canto-Soler, M. Valeria
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Cone photoreceptors in human stem cell-derived retinal organoids demonstrate intrinsic light responses that mimic those of primate fovea
Saha, Aindrila, Capowski, Elizabeth, Fernandez Zepeda, Maria A., Nelson, Emma C., Gamm, David M., Sinha, Raunak
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Isolation of Human Photoreceptor Precursors via a Cell Surface Marker Panel from Stem Cell‐Derived Retinal Organoids and Fetal Retinae
Lakowski, Jörn, Welby, Emily, Budinger, Dimitri, Di Marco, Fabiana, Di Foggia, Valentina, Bainbridge, James W.B., Wallace, Kyle, Gamm, David M., Ali, Robin R., Sowden, Jane C.
Published in Stem cells (Dayton, Ohio) (01.05.2018)
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Modeling early retinal development with human embryonic and induced pluripotent stem cells
Meyer, Jason S, Shearer, Rebecca L, Capowski, Elizabeth E, Wright, Lynda S, Wallace, Kyle A, McMillan, Erin L, Zhang, Su-Chun, Gamm, David M
Published in Proceedings of the National Academy of Sciences - PNAS (29.09.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (29.09.2009)
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Optic Vesicle‐like Structures Derived from Human Pluripotent Stem Cells Facilitate a Customized Approach to Retinal Disease Treatment
Meyer, Jason S., Howden, Sara E., Wallace, Kyle A., Verhoeven, Amelia D., Wright, Lynda S., Capowski, Elizabeth E., Pinilla, Isabel, Martin, Jessica M., Tian, Shulan, Stewart, Ron, Pattnaik, Bikash, Thomson, James A., Gamm, David M.
Published in Stem cells (Dayton, Ohio) (01.08.2011)
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Biallelic Mutations in MITF Cause Coloboma, Osteopetrosis, Microphthalmia, Macrocephaly, Albinism, and Deafness
George, Aman, Zand, Dina J., Hufnagel, Robert B., Sharma, Ruchi, Sergeev, Yuri V., Legare, Janet M., Rice, Gregory M., Scott Schwoerer, Jessica A., Rius, Mariana, Tetri, Laura, Gamm, David M., Bharti, Kapil, Brooks, Brian P.
Published in American journal of human genetics (01.12.2016)
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Drusen in patient-derived hiPSC-RPE models of macular dystrophies
Galloway, Chad A., Dalvi, Sonal, Hung, Sandy S. C., MacDonald, Leslie A., Latchney, Lisa R., Wong, Raymond C. B., Guymer, Robyn H., Mackey, David A., Williams, David S., Chung, Mina M., Gamm, David M., Pébay, Alice, Hewitt, Alex W., Singh, Ruchira
Published in Proceedings of the National Academy of Sciences - PNAS (26.09.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (26.09.2017)
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Bestrophinopathy: An RPE-photoreceptor interface disease
Guziewicz, Karina E., Sinha, Divya, Gómez, Néstor M., Zorych, Kathryn, Dutrow, Emily V., Dhingra, Anuradha, Mullins, Robert F., Stone, Edwin M., Gamm, David M., Boesze-Battaglia, Kathleen, Aguirre, Gustavo D.
Published in Progress in retinal and eye research (01.05.2017)
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The NIH Somatic Cell Genome Editing program
Saha, Krishanu, Sontheimer, Erik J., Brooks, P. J., Dwinell, Melinda R., Gersbach, Charles A., Liu, David R., Murray, Stephen A., Tsai, Shengdar Q., Wilson, Ross C., Anderson, Daniel G., Asokan, Aravind, Banfield, Jillian F., Bankiewicz, Krystof S., Bao, Gang, Bulte, Jeff W. M., Bursac, Nenad, Campbell, Jarryd M., Carlson, Daniel F., Chaikof, Elliot L., Chen, Zheng-Yi, Cheng, R. Holland, Clark, Karl J., Curiel, David T., Dahlman, James E., Deverman, Benjamin E., Dickinson, Mary E., Doudna, Jennifer A., Ekker, Stephen C., Emborg, Marina E., Feng, Guoping, Freedman, Benjamin S., Gamm, David M., Gao, Guangping, Ghiran, Ionita C., Glazer, Peter M., Gong, Shaoqin, Heaney, Jason D., Hennebold, Jon D., Hinson, John T., Khvorova, Anastasia, Kiani, Samira, Lagor, William R., Lam, Kit S., Leong, Kam W., Levine, Jon E., Lewis, Jennifer A., Lutz, Cathleen M., Ly, Danith H., Maragh, Samantha, McCray, Paul B., McDevitt, Todd C., Mirochnitchenko, Oleg, Morizane, Ryuji, Murthy, Niren, Prather, Randall S., Ronald, John A., Roy, Subhojit, Roy, Sushmita, Sabbisetti, Venkata, Saltzman, W. Mark, Santangelo, Philip J., Segal, David J., Shimoyama, Mary, Skala, Melissa C., Tarantal, Alice F., Tilton, John C., Truskey, George A., Vandsburger, Moriel, Watts, Jonathan K., Wells, Kevin D., Wolfe, Scot A., Xu, Qiaobing, Xue, Wen, Yi, Guohua, Zhou, Jiangbing
Published in Nature (London) (08.04.2021)
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3D Microstructured Scaffolds to Support Photoreceptor Polarization and Maturation
Jung, Yei Hwan, Phillips, M. Joseph, Lee, Juhwan, Xie, Ruosen, Ludwig, Allison L., Chen, Guojun, Zheng, Qifeng, Kim, Tong June, Zhang, Huilong, Barney, Patrick, Min, Jee, Barlow, Katherine, Gong, Shaoqin, Gamm, David M., Ma, Zhenqiang
Published in Advanced materials (Weinheim) (01.09.2018)
Published in Advanced materials (Weinheim) (01.09.2018)
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Nonviral base editing of KCNJ13 mutation preserves vision in a model of inherited retinal channelopathy
Kabra, Meha, Shahi, Pawan K, Wang, Yuyuan, Sinha, Divya, Spillane, Allison, Newby, Gregory A, Saxena, Shivani, Tong, Yao, Chang, Yu, Abdeen, Amr A, Edwards, Kimberly L, Theisen, Cole O, Liu, David R, Gamm, David M, Gong, Shaoqin, Saha, Krishanu, Pattnaik, Bikash R
Published in The Journal of clinical investigation (01.10.2023)
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A Novel Approach to Single Cell RNA‐Sequence Analysis Facilitates In Silico Gene Reporting of Human Pluripotent Stem Cell‐Derived Retinal Cell Types
Phillips, M. Joseph, Jiang, Peng, Howden, Sara, Barney, Patrick, Min, Jee, York, Nathaniel W., Chu, Li‐Fang, Capowski, Elizabeth E., Cash, Abigail, Jain, Shivani, Barlow, Katherine, Tabassum, Tasnia, Stewart, Ron, Pattnaik, Bikash R., Thomson, James A., Gamm, David M.
Published in Stem cells (Dayton, Ohio) (01.03.2018)
Published in Stem cells (Dayton, Ohio) (01.03.2018)
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Re-formation of synaptic connectivity in dissociated human stem cell-derived retinal organoid cultures
Ludwig, Allison L, Mayerl, Steven J, Gao, Yu, Banghart, Mark, Bacig, Cole, Fernandez Zepeda, Maria A, Zhao, Xinyu, Gamm, David M
Published in Proceedings of the National Academy of Sciences - PNAS (10.01.2023)
Published in Proceedings of the National Academy of Sciences - PNAS (10.01.2023)
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Gene Augmentation and Readthrough Rescue Channelopathy in an iPSC-RPE Model of Congenital Blindness
Shahi, Pawan K., Hermans, Dalton, Sinha, Divya, Brar, Simran, Moulton, Hannah, Stulo, Sabrina, Borys, Katarzyna D., Capowski, Elizabeth, Pillers, De-Ann M., Gamm, David M., Pattnaik, Bikash R.
Published in American journal of human genetics (07.02.2019)
Published in American journal of human genetics (07.02.2019)
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Use of Topical Insulin to Treat Refractory Neurotrophic Corneal Ulcers
Wang, Angeline L, Weinlander, Eric, Metcalf, Brandon M, Barney, Neal P, Gamm, David M, Nehls, Sarah M, Struck, Michael C
Published in Cornea (01.11.2017)
Published in Cornea (01.11.2017)
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Human iPSC Modeling Reveals Mutation-Specific Responses to Gene Therapy in a Genotypically Diverse Dominant Maculopathy
Sinha, Divya, Steyer, Benjamin, Shahi, Pawan K., Mueller, Katherine P., Valiauga, Rasa, Edwards, Kimberly L., Bacig, Cole, Steltzer, Stephanie S., Srinivasan, Sandhya, Abdeen, Amr, Cory, Evan, Periyasamy, Viswesh, Siahpirani, Alireza Fotuhi, Stone, Edwin M., Tucker, Budd A., Roy, Sushmita, Pattnaik, Bikash R., Saha, Krishanu, Gamm, David M.
Published in American journal of human genetics (06.08.2020)
Published in American journal of human genetics (06.08.2020)
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