Infection of human Nasal Epithelial Cells with SARS-CoV-2 and a 382-nt deletion isolate lacking ORF8 reveals similar viral kinetics and host transcriptional profiles
Gamage, Akshamal M, Tan, Kai Sen, Chan, Wharton O Y, Liu, Jing, Tan, Chee Wah, Ong, Yew Kwang, Thong, Mark, Andiappan, Anand K, Anderson, Danielle E, Wang, De Yun, Wang, Lin-Fa
Published in PLoS pathogens (01.12.2020)
Published in PLoS pathogens (01.12.2020)
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Longitudinal single cell atlas identifies complex temporal relationship between type I interferon response and COVID-19 severity
Lin, Quy Xiao Xuan, Rajagopalan, Deepa, Gamage, Akshamal M, Tan, Le Min, Venkatesh, Prasanna Nori, Chan, Wharton O Y, Kumar, Dilip, Agrawal, Ragini, Chen, Yao, Fong, Siew-Wai, Singh, Amit, Sun, Louisa J, Tan, Seow-Yen, Chai, Louis Yi Ann, Somani, Jyoti, Lee, Bernett, Renia, Laurent, Ng, Lisa F P, Ramanathan, Kollengode, Wang, Lin-Fa, Young, Barnaby, Lye, David, Singhal, Amit, Prabhakar, Shyam
Published in Nature communications (18.01.2024)
Published in Nature communications (18.01.2024)
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The establishment of COPD organoids to study host-pathogen interaction reveals enhanced viral fitness of SARS-CoV-2 in bronchi
Chan, Louisa L Y, Anderson, Danielle E, Cheng, Hong Sheng, Ivan, Fransiskus Xaverius, Chen, Si, Kang, Adrian E Z, Foo, Randy, Gamage, Akshamal M, Tiew, Pei Yee, Koh, Mariko Siyue, Lee, Ken Cheah Hooi, Nichol, Kristy, Pathinayake, Prabuddha S, Chan, Yik Lung, Yeo, Tsin Wen, Oliver, Brian G, Wark, Peter A B, Liu, Linbo, Tan, Nguan Soon, Wang, Lin-Fa, Chotirmall, Sanjay H
Published in Nature communications (10.12.2022)
Published in Nature communications (10.12.2022)
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Human Nasal Epithelial Cells Sustain Persistent SARS-CoV-2 Infection In Vitro , despite Eliciting a Prolonged Antiviral Response
Gamage, Akshamal M, Tan, Kai Sen, Chan, Wharton O Y, Lew, Zhe Zhang Ryan, Liu, Jing, Tan, Chee Wah, Rajagopalan, Deepa, Lin, Quy Xiao Xuan, Tan, Le Min, Venkatesh, Prasanna Nori, Ong, Yew Kwang, Thong, Mark, Lin, Raymond Tzer Pin, Prabhakar, Shyam, Wang, De Yun, Wang, Lin-Fa
Published in mBio (22.02.2022)
Published in mBio (22.02.2022)
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Journal Article
Pteropine orthoreoviruses use cell surface heparan sulphate as an attachment receptor
Tan, Chee Wah, Gamage, Akshamal M., Yap, Wee Chee, Wei Tang, Leon Jia, Sun, Yuan, Yang, Xing-Lou, Pyke, Alyssa, Chua, Kaw Bing, Wang, Lin-Fa
Published in Emerging microbes & infections (01.12.2023)
Published in Emerging microbes & infections (01.12.2023)
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Journal Article
Generation of self-replicating airway organoids from the cave nectar bat Eonycteris spelaea as a model system for studying host-pathogen interactions in the bat airway epithelium
Chan, Louisa L.Y., Gamage, Akshamal M., Tan, Chee Wah, Tan, Kai Sen, Liu, Jing, Tay, Douglas Jie Wen, Foo, Randy Jee Hiang, Rénia, Laurent, Wang, De Yun, Wang, Lin-Fa
Published in Emerging microbes & infections (01.12.2023)
Published in Emerging microbes & infections (01.12.2023)
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Betacoronaviruses SARS-CoV-2 and HCoV-OC43 infections in IGROV-1 cell line require aryl hydrocarbon receptor
Yousefi, Meisam, Lee, Wai Suet, Chan, Wharton O. Y., He, Wei, Mah, Marcus G., Yong, Cythia Lingli, Deerain, Joshua M., Wang, Lijin, Arcinas, Camille, Yan, Biaoguo, Tan, Dewei, Sia, Wan Rong, Gamage, Akshamal M., Yang, Jinxuan, Hsu, Alan Chen-Yu, Li, Shang, Linster, Martin, Yang, Xinglou, Ghosh, Sujoy, Anderson, Danielle E., Smith, Gavin J. D., Tan, Chee Wah, Wang, Lin-Fa, Ooi, Yaw Shin
Published in Emerging microbes & infections (01.12.2023)
Published in Emerging microbes & infections (01.12.2023)
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Decoding bat immunity: the need for a coordinated research approach
Wang, Lin-Fa, Gamage, Akshamal M, Chan, Wharton O Y, Hiller, Michael, Teeling, Emma C
Published in Nature reviews. Immunology (01.05.2021)
Published in Nature reviews. Immunology (01.05.2021)
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Journal Article
Single-cell transcriptome analysis of the in vivo response to viral infection in the cave nectar bat Eonycteris spelaea
Gamage, Akshamal M., Chan, Wharton O.Y., Zhu, Feng, Lim, Yan Ting, Long, Sandy, Ahn, Matae, Tan, Chee Wah, Hiang Foo, Randy Jee, Sia, Wan Rong, Lim, Xiao Fang, He, Haopeng, Zhai, Weiwei, Anderson, Danielle E., Sobota, Radoslaw Mikolaj, Dutertre, Charles-Antoine, Wang, Lin-Fa
Published in Immunity (Cambridge, Mass.) (08.11.2022)
Published in Immunity (Cambridge, Mass.) (08.11.2022)
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Immunophenotyping monocytes, macrophages and granulocytes in the Pteropodid bat Eonycteris spelaea
Gamage, Akshamal M, Zhu, Feng, Ahn, Matae, Foo, Randy Jee Hiang, Hey, Ying Ying, Low, Dolyce H W, Mendenhall, Ian H, Dutertre, Charles-Antoine, Wang, Lin-Fa
Published in Scientific reports (15.01.2020)
Published in Scientific reports (15.01.2020)
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The proteobacterial species Burkholderia pseudomallei produces ergothioneine, which enhances virulence in mammalian infection
Gamage, Akshamal M, Liao, Cangsong, Cheah, Irwin K, Chen, Yahua, Lim, Daniel R X, Ku, Joanne W K, Chee, Rhonda Sin Ling, Gengenbacher, Martin, Seebeck, Florian P, Halliwell, Barry, Gan, Yunn-Hwen
Published in The FASEB journal (01.12.2018)
Published in The FASEB journal (01.12.2018)
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Application of a bespoke monoclonal antibody panel to characterize immune cell populations in cave nectar bats
Chen, Shiwei, Sia, Wan Rong, Tang, Leon J.W., Gamage, Akshamal M., Chan, Wharton O.Y., Zhu, Feng, Chia, Wanni, Kwek, Madeline S.S., Kong, Pui San, Lim, Beng Lee, Foo, Randy, Ng, Wei Lun, Tan, Adrian H.J., He, Shan, Loh, Abigail Y.T., Low, Dolyce H.W., Smith, Gavin J.D., Hong, Lewis Z., Wang, Lin-Fa
Published in Cell reports (Cambridge) (22.10.2024)
Published in Cell reports (Cambridge) (22.10.2024)
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Journal Article
Application of a bespoke monoclonal antibody panel to characterize immune cell populations in cave nectar bats
Chen, Shiwei, Sia, Wan Rong, Tang, Leon J.W., Gamage, Akshamal M., Chan, Wharton O.Y., Zhu, Feng, Chia, Wanni, Kwek, Madeline S.S., Kong, Pui San, Lim, Beng Lee, Foo, Randy, Ng, Wei Lun, Tan, Adrian H.J., He, Shan, Loh, Abigail Y.T., Low, Dolyce H.W., Smith, Gavin J.D., Hong, Lewis Z., Wang, Lin-Fa
Published in Cell reports (Cambridge) (24.09.2024)
Published in Cell reports (Cambridge) (24.09.2024)
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