Microglia affect α-synuclein cell-to-cell transfer in a mouse model of Parkinson's disease
George, Sonia, Rey, Nolwen L, Tyson, Trevor, Esquibel, Corinne, Meyerdirk, Lindsay, Schulz, Emily, Pierce, Steven, Burmeister, Amanda R, Madaj, Zachary, Steiner, Jennifer A, Escobar Galvis, Martha L, Brundin, Lena, Brundin, Patrik
Published in Molecular neurodegeneration (16.08.2019)
Published in Molecular neurodegeneration (16.08.2019)
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Journal Article
Mitochondrial pyruvate carrier regulates autophagy, inflammation, and neurodegeneration in experimental models of Parkinson's disease
Ghosh, Anamitra, Tyson, Trevor, George, Sonia, Hildebrandt, Erin N, Steiner, Jennifer A, Madaj, Zachary, Schulz, Emily, Machiela, Emily, McDonald, William G, Escobar Galvis, Martha L, Kordower, Jeffrey H, Van Raamsdonk, Jeremy M, Colca, Jerry R, Brundin, Patrik
Published in Science translational medicine (07.12.2016)
Published in Science translational medicine (07.12.2016)
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Journal Article
Cytokines and tryptophan metabolites can predict depressive symptoms in pregnancy
Sha, Qiong, Madaj, Zach, Keaton, Sarah, Escobar Galvis, Martha L, Smart, LeAnn, Krzyzanowski, Stanislaw, Fazleabas, Asgerally T, Leach, Richard, Postolache, Teodor T, Achtyes, Eric D, Brundin, Lena
Published in Translational psychiatry (26.01.2022)
Published in Translational psychiatry (26.01.2022)
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Journal Article
Dysregulated placental expression of kynurenine pathway enzymes is associated with inflammation and depression in pregnancy
Sha, Qiong, Escobar Galvis, Martha L, Madaj, Zachary B., Keaton, Sarah A., Smart, LeAnn, Edgerly, Yvonne M., Anis, Ehraz, Leach, Richard, Osborne, Lauren M., Achtyes, Eric, Brundin, Lena
Published in Brain, behavior, and immunity (01.07.2024)
Published in Brain, behavior, and immunity (01.07.2024)
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Journal Article
Synaptic location is a determinant of the detrimental effects of α-synuclein pathology to glutamatergic transmission in the basolateral amygdala
Chen, Liqiang, Nagaraja, Chetan, Daniels, Samuel, Fisk, Zoe A, Dvorak, Rachel, Meyerdirk, Lindsay, Steiner, Jennifer A, Escobar Galvis, Martha L, Henderson, Michael X, Rousseaux, Maxime WC, Brundin, Patrik, Chu, Hong-Yuan
Published in eLife (01.07.2022)
Published in eLife (01.07.2022)
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Journal Article
Maternal Herpesviridae infection during pregnancy alters midbrain dopaminergic signatures in adult offspring
Burmeister, Amanda R., Gordevicius, Juozas, Paul, Emmanuel N., Houck, Christina, George, Sonia, Escobar Galvis, Martha L., Sha, Qiong, Brundin, Patrik, Pospisilik, J. Andrew, Racicot, Karen, Brundin, Lena
Published in Neurobiology of disease (01.07.2022)
Published in Neurobiology of disease (01.07.2022)
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Journal Article
Progressive nigrostriatal terminal dysfunction and degeneration in the engrailed1 heterozygous mouse model of Parkinson's disease
Nordström, Ulrika, Beauvais, Geneviève, Ghosh, Anamitra, Pulikkaparambil Sasidharan, Baby Chakrapani, Lundblad, Martin, Fuchs, Julia, Joshi, Rajiv L, Lipton, Jack W, Roholt, Andrew, Medicetty, Satish, Feinstein, Timothy N, Steiner, Jennifer A, Escobar Galvis, Martha L, Prochiantz, Alain, Brundin, Patrik
Published in Neurobiology of disease (01.01.2015)
Published in Neurobiology of disease (01.01.2015)
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Journal Article
Low plasma serotonin linked to higher nigral iron in Parkinson's disease
Jellen, Leslie C, Lewis, Mechelle M, Du, Guangwei, Wang, Xi, Galvis, Martha L Escobar, Krzyzanowski, Stanislaw, Capan, Colt D, Snyder, Amanda M, Connor, James R, Kong, Lan, Mailman, Richard B, Brundin, Patrik, Brundin, Lena, Huang, Xuemei
Published in Scientific reports (21.12.2021)
Published in Scientific reports (21.12.2021)
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Journal Article
Prior metabolite extraction fully preserves RNAseq quality and enables integrative multi-'omics analysis of the liver metabolic response to viral infection
Madaj, Zachary B, Dahabieh, Michael S., Kamalumpundi, Vijayvardhan, Muhire, Brejnev, Pettinga, J., Siwicki, Rebecca A., Ellis, Abigail E., Isaguirre, Christine, Escobar Galvis, Martha L., DeCamp, Lisa, Jones, Russell G., Givan, Scott A., Adams, Marie, Sheldon, Ryan D.
Published in RNA biology (31.12.2023)
Published in RNA biology (31.12.2023)
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Journal Article
Best practice: setting up and operating a mid-sized cryo-EM facility
Meng, Xing, Ratnayake, Ishara, Escobar Galvis, Martha L, Kotecki, Jason, Ramjan, Zack, Zhao, Gongpu
Published in Frontiers in molecular biosciences (27.11.2023)
Published in Frontiers in molecular biosciences (27.11.2023)
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Journal Article
In vivo Fragmentation of Heparan Sulfate by Heparanase Overexpression Renders Mice Resistant to Amyloid Protein A Amyloidosis
Li, Jin-Ping, Martha L. Escobar Galvis, Gong, Feng, Zhang, Xiao, Zcharia, Eyal, Metzger, Shula, Vlodavsky, Israel, Kisilevsky, Robert, Lindahl, Ulf, Gajdusek, D. Carleton
Published in Proceedings of the National Academy of Sciences - PNAS (03.05.2005)
Published in Proceedings of the National Academy of Sciences - PNAS (03.05.2005)
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Journal Article
Is the Enzyme ACMSD a Novel Therapeutic Target in Parkinson’s Disease?
Thirtamara-Rajamani, Keerthi, Li, Peipei, Escobar Galvis, Martha L., Labrie, Viviane, Brundin, Patrik, Brundin, Lena
Published in Journal of Parkinson's disease (01.01.2017)
Published in Journal of Parkinson's disease (01.01.2017)
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Journal Article
Transgenic or tumor-induced expression of heparanase upregulates sulfation of heparan sulfate
Li, Jin-Ping, Escobar Galvis, Martha L, Jia, Juan, Zhang, Xiao, Jastrebova, Nadja, Spillmann, Dorothe, Gottfridsson, Eva, van Kuppevelt, Toin H, Zcharia, Eyal, Vlodavsky, Israel, Lindahl, Ulf
Published in Nature chemical biology (01.12.2007)
Published in Nature chemical biology (01.12.2007)
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Journal Article
Tryptophan Metabolites Are Associated With Symptoms and Nigral Pathology in Parkinson's Disease
Heilman, Patrick L., Wang, Ernest W., Lewis, Mechelle M., Krzyzanowski, Stanislaw, Capan, Colt D., Burmeister, Amanda R., Du, Guangwei, Escobar Galvis, Martha L., Brundin, Patrik, Huang, Xuemei, Brundin, Lena
Published in Movement disorders (01.11.2020)
Published in Movement disorders (01.11.2020)
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Journal Article
Inflammation and kynurenine pathway dysregulation in post-partum women with severe and suicidal depression
Achtyes, Eric, Keaton, Sarah A., Smart, LeAnn, Burmeister, Amanda R., Heilman, Patrick L., Krzyzanowski, Stanislaw, Nagalla, Madhavi, Guillemin, Gilles J., Escobar Galvis, Martha L., Lim, Chai K., Muzik, Maria, Postolache, Teodor T., Leach, Richard, Brundin, Lena
Published in Brain, behavior, and immunity (01.01.2020)
Published in Brain, behavior, and immunity (01.01.2020)
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Journal Article
Air pollution nanoparticle and alpha-synuclein fibrils synergistically decrease glutamate receptor A1, depending upon nPM batch activity
Zhang, Hongqiao, D'Agostino, Carla, Tulisiak, Christopher, Thorwald, Max A., Bergkvist, Liza, Lindquist, Allison, Meyerdirk, Lindsay, Schulz, Emily, Becker, Katelyn, Steiner, Jennifer A., Cacciottolo, Mafalda, Kwatra, Mohit, Rey, Nolwen L., Escobar Galvis, Martha L., Ma, Jiyan, Sioutas, Constantinos, Morgan, Todd E., Finch, Caleb E., Brundin, Patrik
Published in Heliyon (01.04.2023)
Published in Heliyon (01.04.2023)
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Journal Article
Integrative transcriptome- and DNA methylation analysis of brain tissue from the temporal pole in suicide decedents and their controls
Sha, Qiong, Fu, Zhen, Escobar Galvis, Martha L, Madaj, Zach, Underwood, Mark D, Steiner, Jennifer A, Dwork, Andrew, Simpson, Norman, Galfalvy, Hanga, Rozoklija, Gorazd, Achtyes, Eric D, Mann, J John, Brundin, Lena
Published in Molecular psychiatry (01.01.2024)
Published in Molecular psychiatry (01.01.2024)
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Journal Article
A diverse proteome is present and enzymatically active in metabolite extracts
House, Rachel J., Soper-Hopper, Molly T., Vincent, Michael P., Ellis, Abigail E., Capan, Colt D., Madaj, Zachary B., Wolfrum, Emily, Isaguirre, Christine N., Castello, Carlos D., Johnson, Amy B., Escobar Galvis, Martha L., Williams, Kelsey S., Lee, Hyoungjoo, Sheldon, Ryan D.
Published in Nature communications (10.07.2024)
Published in Nature communications (10.07.2024)
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Journal Article
T Cells Limit Accumulation of Aggregate Pathology Following Intrastriatal Injection of α-Synuclein Fibrils
George, Sonia, Tyson, Trevor, Rey, Nolwen L, Sheridan, Rachael, Peelaerts, Wouter, Becker, Katelyn, Schulz, Emily, Meyerdirk, Lindsay, Burmeister, Amanda R, von Linstow, Christian U, Steiner, Jennifer A, Galvis, Martha L Escobar, Ma, Jiyan, Pospisilik, J Andrew, Labrie, Viviane, Brundin, Lena, Brundin, Patrik
Published in Journal of Parkinson's disease (01.01.2021)
Published in Journal of Parkinson's disease (01.01.2021)
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Journal Article
Loss of One Engrailed1 Allele Enhances Induced α-Synucleinopathy
Chatterjee, Diptaman, Sanchez, Daniel Saiz, Quansah, Emmanuel, Rey, Nolwen L, George, Sonia, Becker, Katelyn, Madaj, Zachary, Steiner, Jennifer A, Ma, Jiyan, Escobar Galvis, Martha L, Kordower, Jeffrey H, Brundin, Patrik
Published in Journal of Parkinson's disease (01.01.2019)
Published in Journal of Parkinson's disease (01.01.2019)
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Journal Article