A tetravalent bispecific TandAb (CD19/CD3), AFM11, efficiently recruits T cells for the potent lysis of CD19+ tumor cells
Reusch, Uwe, Duell, Johannes, Ellwanger, Kristina, Herbrecht, Carmen, Knackmuss, Stefan HJ, Fucek, Ivica, Eser, Markus, McAleese, Fionnuala, Molkenthin, Vera, Le Gall, Fabrice, Topp, Max, Little, Melvyn, Zhukovsky, Eugene A
Published in mAbs (04.05.2015)
Published in mAbs (04.05.2015)
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Journal Article
A novel tetravalent bispecific TandAb (CD30/CD16A) efficiently recruits NK cells for the lysis of CD30+ tumor cells
Reusch, Uwe, Burkhardt, Carmen, Fucek, Ivica, Le Gall, Fabrice, Le Gall, Mikaelle, Hoffmann, Karin, Knackmuss, Stefan HJ, Kiprijanov, Sergej, Little, Melvyn, Zhukovsky, Eugene A
Published in mAbs (01.05.2014)
Published in mAbs (01.05.2014)
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Journal Article
Inhibition of Melanoma Growth by Targeting of Antigen to Dendritic Cells via an Anti-DEC-205 Single-Chain Fragment Variable Molecule
Johnson, Theron S, Mahnke, Karsten, Storn, Volker, Schönfeld, Kurt, Ring, Sabine, Nettelbeck, Dirk M, Haisma, Hidde J, Le Gall, Fabrice, Kontermann, Roland E, Enk, Alexander H
Published in Clinical cancer research (15.12.2008)
Published in Clinical cancer research (15.12.2008)
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Effect of linker sequences between the antibody variable domains on the formation, stability and biological activity of a bispecific tandem diabody
Le Gall, Fabrice, Reusch, Uwe, Little, Melvyn, Kipriyanov, Sergey M.
Published in Protein engineering, design and selection (01.04.2004)
Published in Protein engineering, design and selection (01.04.2004)
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Journal Article
Synergistic Antitumor Effect of Bispecific CD19 × CD3 and CD19 × CD16 Diabodies in a Preclinical Model of Non-Hodgkin’s Lymphoma
Kipriyanov, Sergey M., Cochlovius, Björn, Schäfer, Holger J., Moldenhauer, Gerhard, Bähre, Alexandra, Le Gall, Fabrice, Knackmuss, Stefan, Little, Melvyn
Published in The Journal of immunology (1950) (01.07.2002)
Published in The Journal of immunology (1950) (01.07.2002)
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Journal Article
Effect of Domain Order on the Activity of Bacterially Produced Bispecific Single-chain Fv Antibodies
Kipriyanov, Sergey M., Moldenhauer, Gerhard, Braunagel, Michael, Reusch, Uwe, Cochlovius, Björn, Le Gall, Fabrice, Kouprianova, Olga A., Von der Lieth, Claus-Wilhelm, Little, Melvyn
Published in Journal of molecular biology (27.06.2003)
Published in Journal of molecular biology (27.06.2003)
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Engineering of a single-chain variable-fragment (scFv) antibody specific for the stolbur phytoplasma (mollicute) and its expression in Escherichia coli and tobacco plants
Le Gall, F. (Institut National de la Recherche Agronomique, France.), Bove, J.M, Garnier, M
Published in Applied and Environmental Microbiology (01.11.1998)
Published in Applied and Environmental Microbiology (01.11.1998)
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Transformation of tobacco plants for single-chain antibody expression via apoplastic and symplasmic routes, and analysis of their susceptibility to stolbur phytoplasma infection
Malembic-Maher, Sylvie, Gall, Fabrice Le, Danet, Jean-Luc, Borne, François Dorlhac de, Bové, Joseph-Marie, Garnier-Semancik, Monique
Published in Plant science (Limerick) (01.02.2005)
Published in Plant science (Limerick) (01.02.2005)
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Journal Article
Preclinical development of an anti-CD30/anti-CD16A bispecific tetravalent TandAb antibody for the treatment of Hodgkin lymphoma
Knackmuss, Stefan, Reusch, Uwe, Burkhardt, Carmen, Fucek, Ivica, Le Gall, Fabrice, Pauels, Hans-Gerd, Little, Melvyn, Zhukovsky, Eugene
Published in Journal of clinical oncology (20.05.2012)
Published in Journal of clinical oncology (20.05.2012)
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Journal Article
Abstract 3522: Preclinical development of an anti-CD30/anti-CD16A bispecific tetravalent TandAb antibody for the treatment of Hodgkin lymphoma
Knackmuss, Stefan H., Reusch, Uwe, Burkhardt, Carmen, Fucek, Ivica, Gall, Fabrice Le, Pauels, Hans-Gerd, Zhukovsky, Eugene A., Little, Melvyn
Published in Cancer research (Chicago, Ill.) (15.04.2012)
Published in Cancer research (Chicago, Ill.) (15.04.2012)
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68Ga-labelled recombinant antibody variants for immuno-PET imaging of solid tumours
Eder, Matthias, Knackmuss, Stefan, Le Gall, Fabrice, Reusch, Uwe, Rybin, Vladimir, Little, Melvyn, Haberkorn, Uwe, Mier, Walter, Eisenhut, Michael
Published in European journal of nuclear medicine and molecular imaging (01.07.2010)
Published in European journal of nuclear medicine and molecular imaging (01.07.2010)
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Journal Article
Effect of tetravalent bispecific CD19xCD3 recombinant antibody construct and CD28 costimulation on lysis of malignant B cells from patients with chronic lymphocytic leukemia by autologous T cells
Reusch, Uwe, Le Gall, Fabrice, Hensel, Manfred, Moldenhauer, Gerhard, Ho, Anthony D, Little, Melvyn, Kipriyanov, Sergey M
Published in International journal of cancer (10.11.2004)
Published in International journal of cancer (10.11.2004)
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Journal Article
Synergistic Antitumor Effect of Bispecific CD19 x CD3 and CD19 x CD16 Diabodies in a Preclinical Model of Non-Hodgkin's Lymphoma
Kipriyanov, Sergey M, Cochlovius, Bjorn, Schafer, Holger J, Moldenhauer, Gerhard, Bahre, Alexandra, Le Gall, Fabrice, Knackmuss, Stefan, Little, Melvyn
Published in The Journal of immunology (1950) (01.07.2002)
Published in The Journal of immunology (1950) (01.07.2002)
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Journal Article
Immunosuppressive properties of anti-CD3 single-chain Fv and diabody
Le Gall, Fabrice, Reusch, Uwe, Moldenhauer, Gerhard, Little, Melvyn, Kipriyanov, Sergey M.
Published in Journal of immunological methods (01.02.2004)
Published in Journal of immunological methods (01.02.2004)
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