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Published in Journal of medicinal chemistry (24.10.2019)
Published in Journal of medicinal chemistry (24.10.2019)
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Topological organization of CA 3‐to‐ CA 1 excitation
Hongo, Yoshie, Ogawa, Koichi, Takahara, Yuji, Takasu, Keiko, Royer, Sebastien, Hasegawa, Minoru, Sakaguchi, Gaku, Ikegaya, Yuji
Published in The European journal of neuroscience (01.09.2015)
Published in The European journal of neuroscience (01.09.2015)
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G protein‐gated inwardly rectifying potassium (KIR3) channels play a primary role in the antinociceptive effect of oxycodone, but not morphine, at supraspinal sites
Nakamura, Atsushi, Fujita, Masahide, Ono, Hiroko, Hongo, Yoshie, Kanbara, Tomoe, Ogawa, Koichi, Morioka, Yasuhide, Nishiyori, Atsushi, Shibasaki, Masahiro, Mori, Tomohisa, Suzuki, Tsutomu, Sakaguchi, Gaku, Kato, Akira, Hasegawa, Minoru
Published in British journal of pharmacology (01.01.2014)
Published in British journal of pharmacology (01.01.2014)
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Interleukin-1β up-regulates TACE to enhance α-cleavage of APP in neurons: resulting decrease in Aβ production
Tachida, Yuriko, Nakagawa, Kazuhiro, Saito, Takashi, Saido, Takaomi C, Honda, Takashi, Saito, Yuko, Murayama, Shigeo, Endo, Tamao, Sakaguchi, Gaku, Kato, Akira, Kitazume, Shinobu, Hashimoto, Yasuhiro
Published in Journal of neurochemistry (01.03.2008)
Published in Journal of neurochemistry (01.03.2008)
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Sensitization of TRPV1 by protein kinase C in rats with mono-iodoacetate-induced joint pain
Koda, Ken, Hyakkoku, Kana, Ogawa, Koichi, Takasu, Keiko, Imai, Sunao, Sakurai, Yusuke, Fujita, Masahide, Ono, Hiroko, Yamamoto, Miyuki, Fukuda, Isao, Yamane, Shoji, Morita, Atsushi, Asaki, Toshiyuki, Kanemasa, Toshiyuki, Sakaguchi, Gaku, Morioka, Yasuhide, PhD
Published in Osteoarthritis and cartilage (01.07.2016)
Published in Osteoarthritis and cartilage (01.07.2016)
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Morphine and oxycodone, but not fentanyl, exhibit antinociceptive effects mediated by G-protein inwardly rectifying potassium (GIRK) channels in an oxaliplatin-induced neuropathy rat model
Kanbara, Tomoe, Nakamura, Atsushi, Shibasaki, Masahiro, Mori, Tomohisa, Suzuki, Tsutomu, Sakaguchi, Gaku, Kanemasa, Toshiyuki
Published in Neuroscience letters (19.09.2014)
Published in Neuroscience letters (19.09.2014)
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G protein-gated inwardly rectifying potassium (K sub(IR)3) channels play a primary role in the antinociceptive effect of oxycodone, but not morphine, at supraspinal sites
Nakamura, Atsushi, Fujita, Masahide, Ono, Hiroko, Hongo, Yoshie, Kanbara, Tomoe, Ogawa, Koichi, Morioka, Yasuhide, Nishiyori, Atsushi, Shibasaki, Masahiro, Mori, Tomohisa, Suzuki, Tsutomu, Sakaguchi, Gaku, Kato, Akira, Hasegawa, Minoru
Published in British journal of pharmacology (01.01.2014)
Published in British journal of pharmacology (01.01.2014)
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Trifluoromethyl Dihydrothiazine‐Based β‐Secretase (BACE1) Inhibitors with Robust Central β‐Amyloid Reduction and Minimal Covalent Binding Burden
Anan, Kosuke, Iso, Yasuyoshi, Oguma, Takuya, Nakahara, Kenji, Suzuki, Shinji, Yamamoto, Takahiko, Matsuoka, Eriko, Ito, Hisanori, Sakaguchi, Gaku, Ando, Shigeru, Morimoto, Kenji, Kanegawa, Naoki, Kido, Yasuto, Kawachi, Tomoyuki, Fukushima, Tamio, Teisman, Ard, Urmaliya, Vijay, Dhuyvetter, Deborah, Borghys, Herman, Austin, Nigel, Van Den Bergh, An, Verboven, Peter, Bischoff, Francois, Gijsen, Harrie J. M., Yamano, Yoshinori, Kusakabe, Kenichi
Published in ChemMedChem (20.11.2019)
Published in ChemMedChem (20.11.2019)
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Interaction of Doc2 with tctex-1, a Light Chain of Cytoplasmic Dynein
Nagano, Fumiko, Orita, Satoshi, Sasaki, Takuya, Naito, Akira, Sakaguchi, Gaku, Maeda, Miki, Watanabe, Tsuyoshi, Kominami, Eiki, Uchiyama, Yasuo, Takai, Yoshimi
Published in The Journal of biological chemistry (13.11.1998)
Published in The Journal of biological chemistry (13.11.1998)
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Discovery of novel 2′,4′-dimethyl-[4,5′-bithiazol]-2-yl amino derivatives as orally bioavailable TRPV4 antagonists for the treatment of pain: Part 2
Tsuno, Naoki, Yukimasa, Akira, Yoshida, Osamu, Suzuki, Shinji, Nakai, Hiromi, Ogawa, Tomoyuki, Fujiu, Motohiro, Takaya, Kenji, Nozu, Azusa, Yamaguchi, Hiroki, Matsuda, Hidetoshi, Funaki, Satoko, Nishimura, Yoko, Ito, Tetsuji, Nagamatsu, Daiki, Asaki, Toshiyuki, Horita, Narumi, Yamamoto, Miyuki, Hinata, Mikie, Soga, Masahiko, Imai, Masayuki, Morioka, Yasuhide, Kanemasa, Toshiyuki, Sakaguchi, Gaku, Iso, Yasuyoshi
Published in Bioorganic & medicinal chemistry letters (15.10.2016)
Published in Bioorganic & medicinal chemistry letters (15.10.2016)
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Discovery of novel 2′,4′-dimethyl-[4,5′-bithiazol]-2-yl amino derivatives as orally bioavailable TRPV4 antagonists for the treatment of pain: Part 1
Tsuno, Naoki, Yukimasa, Akira, Yoshida, Osamu, Ichihashi, Yusuke, Inoue, Takatsugu, Ueno, Tatsuhiko, Yamaguchi, Hiroki, Matsuda, Hidetoshi, Funaki, Satoko, Yamanada, Natsue, Tanimura, Miki, Nagamatsu, Daiki, Nishimura, Yoko, Ito, Tetsuji, Soga, Masahiko, Horita, Narumi, Yamamoto, Miyuki, Hinata, Mikie, Imai, Masayuki, Morioka, Yasuhide, Kanemasa, Toshiyuki, Sakaguchi, Gaku, Iso, Yasuyoshi
Published in Bioorganic & medicinal chemistry letters (15.10.2016)
Published in Bioorganic & medicinal chemistry letters (15.10.2016)
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Enhanced GABA ergic synaptic transmission at VLPAG neurons and potent modulation by oxycodone in a bone cancer pain model
Takasu, Keiko, Ogawa, Koichi, Nakamura, Atsushi, Kanbara, Tomoe, Ono, Hiroko, Tomii, Takako, Morioka, Yasuhide, Hasegawa, Minoru, Shibasaki, Masahiro, Mori, Tomohisa, Suzuki, Tsutomu, Sakaguchi, Gaku
Published in British journal of pharmacology (01.04.2015)
Published in British journal of pharmacology (01.04.2015)
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Novel binding sites of 15-deoxy-Δ12,14-prostaglandin J2 in plasma membranes from primary rat cortical neurons
Yagami, Tatsurou, Ueda, Keiichi, Asakura, Kenji, Takasu, Nobuo, Sakaeda, Toshiyuki, Itoh, Naohiro, Sakaguchi, Gaku, Kishino, Junji, Nakazato, Hitosi, Katsuyama, Yoshihiko, Nagasaki, Tohru, Okamura, Noboru, Hori, Yozo, Hanasaki, Kohji, Arimura, Akinori, Fujimoto, Masafumi
Published in Experimental cell research (01.11.2003)
Published in Experimental cell research (01.11.2003)
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PRECLINICAL MULTI-SPECIES PHARMACOKINETIC/PHARMACODYNAMIC ANALYSIS OF THE ORAL BACE INHIBITOR JNJ-54861911
Ito, Hisanori, Yamakawa, Hidekuni, Nishitomi, Kouhei, Hosono, Motoko, Unemura, Chie, Azuma, Yuki, Ando, Azusa, Izumi, Takaya, Nakajima, Yoshihiro, Tsuji, Hiroki, Kihara, Tsuyoshi, Jacobs, Tom, Borghys, Herman, Koriyama, Yuji, Kato, Akira, Sakaguchi, Gaku
Published in Alzheimer's & dementia (01.07.2017)
Published in Alzheimer's & dementia (01.07.2017)
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The Contribution of Gi/o Protein to Opioid Antinociception in an Oxaliplatin-Induced Neuropathy Rat Model
Kanbara, Tomoe, Nakamura, Atsushi, Takasu, Keiko, Ogawa, Koichi, Shibasaki, Masahiro, Mori, Tomohisa, Suzuki, Tsutomu, Hasegawa, Minoru, Sakaguchi, Gaku, Kanemasa, Toshiyuki
Published in Journal of pharmacological sciences (19.05.2015)
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Published in Journal of pharmacological sciences (19.05.2015)
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BACE1 inhibition reduces endogenous Abeta and alters APP processing in wild-type mice
NISHITOMI, Kouhei, SAKAGUCHI, Gaku, NAKAJIMA, Yoshihiro, LI, Hui-Fang, TAKEYAMA, Chie, KIHARA, Tsuyoshi, OTA, Akinobu, WONG, Philip C, AISEN, Paul S, KATO, Akira, KINOSHITA, Noriaki, MATSUOKA, Yasuji, HORIKOSHI, Yuko, GRAY, Audrey J, MAEDA, Masahiro, HIRATA-FUKAE, Chiho, BECKER, Amanda G, HOSONO, Motoko, SAKAGUCHI, Isako, SAKURA MINAMI, S
Published in Journal of neurochemistry (01.12.2006)
Published in Journal of neurochemistry (01.12.2006)
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Possible role of scavenger receptor SRCL in the clearance of amyloid-βin Alzheimer's disease
Nakamura, Kenji, Ohya, Wakana, Funakoshi, Hiroshi, Sakaguchi, Gaku, Kato, Akira, Takeda, Masatoshi, Kudo, Takashi, Nakamura, Toshikazu
Published in Journal of neuroscience research (01.09.2006)
Published in Journal of neuroscience research (01.09.2006)
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Establishment of Opioid-Induced Rewarding Effects Under Oxaliplatin- and Paclitaxel-Induced Neuropathy in Rats
Mori, Tomohisa, Kanbara, Tomoe, Harumiya, Masato, Iwase, Yoshiyuki, Masumoto, Aki, Komiya, Sachiko, Nakamura, Atsushi, Shibasaki, Masahiro, Kanemasa, Toshiyuki, Sakaguchi, Gaku, Suzuki, Tsutomu
Published in Journal of pharmacological sciences (19.05.2015)
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Published in Journal of pharmacological sciences (19.05.2015)
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Development of Aβ terminal end-specific antibodies and sensitive ELISA for Aβ variant
Horikoshi, Yuko, Sakaguchi, Gaku, Becker, Amanda G, Gray, Audrey J, Duff, Karen, Aisen, Paul S, Yamaguchi, Haruyasu, Maeda, Masahiro, Kinoshita, Noriaki, Matsuoka, Yasuji
Published in Biochemical and biophysical research communications (02.07.2004)
Published in Biochemical and biophysical research communications (02.07.2004)
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Molecular cloning of mouse Doc2α and distribution of its mRNA in adult mouse brain
Naito, Akira, Orita, Satoshi, Wanaka, Akio, Sasaki, Takuya, Gaku Sakaguchi, Maeda, Miki, Igarashi, Hisanaga, Tohyama, Masaya, Yoshimi Takai
Published in Brain research. Molecular brain research. (01.03.1997)
Published in Brain research. Molecular brain research. (01.03.1997)
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