Bispecific BCMA/CD24 CAR-T cells control multiple myeloma growth
Sun, Fumou, Cheng, Yan, Wanchai, Visanu, Guo, Wancheng, Mery, David, Xu, Hongwei, Gai, Dongzheng, Siegel, Eric, Bailey, Clyde, Ashby, Cody, Al Hadidi, Samer, Schinke, Carolina, Thanendrarajan, Sharmilan, Ma, Yupo, Yi, Qing, Orlowski, Robert Z., Zangari, Maurizio, van Rhee, Frits, Janz, Siegfried, Bishop, Gail, Tricot, Guido, Shaughnessy, John D., Zhan, Fenghuang
Published in Nature communications (19.01.2024)
Published in Nature communications (19.01.2024)
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CST6 suppresses osteolytic bone disease in multiple myeloma by blocking osteoclast differentiation
Gai, Dongzheng, Chen, Jin-Ran, Stewart, James P, Nookaew, Intawat, Habelhah, Hasem, Ashby, Cody, Sun, Fumou, Cheng, Yan, Li, Can, Xu, Hongwei, Peng, Bailu, Garg, Tarun K, Schinke, Carolina, Thanendrarajan, Sharmilan, Zangari, Maurizio, Chen, Fangping, Barlogie, Bart, van Rhee, Frits, Tricot, Guido, Shaughnessy Jr., John D, Zhan, Fenghuang
Published in The Journal of clinical investigation (15.09.2022)
Published in The Journal of clinical investigation (15.09.2022)
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Endoplasmic reticulum stress-related signature predicts prognosis and immune infiltration analysis in acute myeloid leukemia
Dong, Lu, Wang, Haili, Miao, Zefeng, Yu, Yanhui, Gai, Dongzheng, Zhang, Guoxiang, Ge, Li, Shen, Xuliang
Published in Hematology (Luxembourg) (31.12.2023)
Published in Hematology (Luxembourg) (31.12.2023)
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Identification and study of cuproptosis-related genes in prognostic model of multiple myeloma
Wang, Haili, Zhang, Guoxiang, Dong, Lu, Chen, Lu, Liang, Li, Ge, Li, Gai, Dongzheng, Shen, Xuliang
Published in Hematology (Luxembourg) (31.12.2023)
Published in Hematology (Luxembourg) (31.12.2023)
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GPR109A mediates the effects of hippuric acid on regulating osteoclastogenesis and bone resorption in mice
Chen, Jin-Ran, Zhao, Haijun, Wankhade, Umesh D., Chintapalli, Sree V., Li, Can, Gai, Dongzheng, Shankar, Kartik, Zhan, Fenghuang, Lazarenko, Oxana P.
Published in Communications biology (08.01.2021)
Published in Communications biology (08.01.2021)
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A gene signature can predict risk of MGUS progressing to multiple myeloma
Sun, Fumou, Cheng, Yan, Ying, Jun, Mery, David, Al Hadidi, Samer, Wanchai, Visanu, Siegel, Eric R, Xu, Hongwei, Gai, Dongzheng, Ashby, Timothy Cody, Bailey, Clyde, Chen, Jin-Ran, Schinke, Carolina, Thanendrarajan, Sharmilan, Zangari, Maurizio, Janz, Siegfried, Barlogie, Bart, Van Rhee, Frits, Tricot, Guido, Shaughnessy, Jr, John D, Zhan, Fenghuang
Published in Journal of hematology and oncology (29.06.2023)
Published in Journal of hematology and oncology (29.06.2023)
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Journal Article
BCMA- and CST6-specific CAR T cells lyse multiple myeloma cells and suppress murine osteolytic lesions
Sun, Fumou, Cheng, Van, Chen, Jin-Ran, Wanchai, Visanu, Mery, David E, Xu, Hongwei, Gai, Dongzheng, Hadidi, Samer Al, Schinke, Carolina, Thanendrarajan, Sharmilan, Zangari, Maurizio, van Rhee, Frits, Tricot, Guido, Shaughnessy, John D, Zhan, Fenghuang
Published in The Journal of clinical investigation (01.01.2024)
Published in The Journal of clinical investigation (01.01.2024)
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Journal Article
The BCMA-Targeted Fourth-Generation CAR-T Cells Secreting CST6 Against Multiple Myeloma and Suppresses Osteolytic Lesions
Sun, Fumou, Cheng, Yan, Chen, Jin-Ran, Wanchai, Visanu, Mery, David E., Xu, Hongwei, Gai, Dongzheng, Al Hadidi, Samer, Schinke, Carolina, Thanendrarajan, Sharmilan, Zangari, Maurizio, van Rhee, Frits, Shaughnessy, Jr, John D, Tricot, Guido, Zhan, Fenghuang
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Decreased bone resorption in Ezh2 myeloid cell conditional knockout mouse model
Caviness, Perry C., Gai, Dongzheng, Lazarenko, Oxana P., Blackburn, Michael L., Zhan, Fenghuang, Chen, Jin‐Ran
Published in The FASEB journal (01.07.2023)
Published in The FASEB journal (01.07.2023)
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NEK2 Inhibition Enhances the Efficacy of PD-1/PD-L1 Blockade in Multiple Myeloma
Cheng, Yan, Sun, Fumou, Cao, Huojun, Gai, Dongzheng, Peng, Bailu, Xu, Hongwei, van Rhee, Frits, Janz, Siegfried, Tricot, Guido, Shaughnessy, John D, Zhan, Fenghuang
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
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Journal Article
P-066 BCMA-CAR-T cells with synthetic circuits of CST6 lyse tumor cells and suppress osteolytic lesions in multiple myeloma
Sun, Fumou, Cheng, Yan, Chen, Jin-Ran, Gai, Dongzheng, Xu, Hongwei, van Rhee, Frits, Tricot, Guido, Shaughnessy, John, Zhan, Fenghuang
Published in Clinical lymphoma, myeloma and leukemia (01.09.2023)
Published in Clinical lymphoma, myeloma and leukemia (01.09.2023)
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TRIP13 modulates protein deubiquitination and accelerates tumor development and progression of B cell malignancies
Li, Can, Xia, Jiliang, Franqui-Machin, Reinaldo, Chen, Fangping, He, Yanjuan, Ashby, Timothy Cody, Teng, Feixiang, Xu, Hongwei, Liu, Dingxiao, Gai, Dongzheng, Johnson, Sarah K, van Rhee, Frits, Janz, Siegfried, Shaughnessy, John D., Jr, Tricot, Guido, Frech, Ivana, Zhan, Fenghuang
Published in The Journal of clinical investigation (15.07.2021)
Published in The Journal of clinical investigation (15.07.2021)
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Journal Article
BCMA- and CST6-specific CAR T cells lyse multiple myeloma cells and suppress murine osteolytic lesions
Sun, Fumou, Cheng, Yan, Chen, Jin-Ran, Wanchai, Visanu, Mery, David E, Xu, Hongwei, Gai, Dongzheng, Al Hadidi, Samer, Schinke, Carolina, Thanendrarajan, Sharmilan, Zangari, Maurizio, van Rhee, Frits, Tricot, Guido, Shaughnessy, Jr, John D, Zhan, Fenghuang
Published in The Journal of clinical investigation (01.01.2024)
Published in The Journal of clinical investigation (01.01.2024)
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Journal Article
A 12 Gene Signature Accurately Predicts Multiple Myeloma Progression from Monoclonal Gammopathy of Undetermined Significance
Sun, Fumou, Ying, Jun, Cheng, Yan, Mery, David, Wanchai, Visanu, Siegel, Eric R., Xu, Hongwei, Gai, Dongzheng, Xu, Jiahao, Ashby, Timothy Cody, Bailey, Clyde, Al Hadidi, Samer, Schinke, Carolina, Thanendrarajan, Sharmilan, Zangari, Maurizio, van Rhee, Frits, Janz, Siegfried, Tricot, Guido, Shaughnessy, Jr, John D, Zhan, Fenghuang
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Journal Article
CST6 suppresses osteolytic bone disease in multiple myeloma by blocking osteoclast differentiation
Gai, Dongzheng, Chen, Jin-Ran, Stewart, James P, Nookaew, Intawat, Habelhah, Hasem, Ashby, Cody, Sun, Fumou, Cheng, Yan, Li, Can, Xu, Hongwei, Peng, Bailu, Garg, Tarun K, Schinke, Carolina, Thanendrarajan, Sharmilan, Zangari, Maurizio, Chen, Fangping, Barlogie, Bart, Van rhee, Frits, Tricot, Guido, Shaughnessy, John D, Zhan, Fenghuang
Published in The Journal of clinical investigation (01.09.2022)
Published in The Journal of clinical investigation (01.09.2022)
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Journal Article
CST6 Is a Small Autocrine Molecule That Targets Myeloma Growth and Bone Destruction
Gai, Dongzheng, JP, Stewart, Shen, Xuxing, Chen, Jin-Ran, Li, Can, Peng, Bailu, Qiang, Ya-Wei, Yaccoby, Shmuel, Zangari, Maurizio, van Rhee, Frits, Tricot, Guido J., Chen, Lijuan, Shaughnessy, John, Zhan, Fenghuang
Published in Blood (05.11.2020)
Published in Blood (05.11.2020)
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Iron Trafficking through Macrophages Regulates Signaling Pathways in Myeloma
Tan, Xuelian, Ashby, Timothy Cody, Zhu, Yuqi, Li, Can, Shen, Xuxing, Brockman, Qierra, Gai, Dongzheng, Johnson, Sarah K, Yong, Donghoon, Schinke, Carolina D., Zangari, Maurizio, van Rhee, Frits, Shaughnessy, John, Huang, Dingming, Frech, Ivana, Tricot, Guido J., Zhan, Fenghuang
Published in Blood (05.11.2020)
Published in Blood (05.11.2020)
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High NEK2 expression in myeloid progenitors suppresses T cell immunity in multiple myeloma
Cheng, Yan, Sun, Fumou, Alapat, Daisy V., Wanchai, Visanu, Mery, David, Guo, Wancheng, Cao, Huojun, Zhu, Yuqi, Ashby, Cody, Bauer, Michael Anton, Nookaew, Intawat, Siegel, Eric R., Ying, Jun, Chen, Jin-Ran, Gai, Dongzheng, Peng, Bailu, Xu, Hongwei, Bailey, Clyde, Al Hadidi, Samer, Schinke, Carolina, Thanendrarajan, Sharmilan, Zangari, Maurizio, Chesi, Marta, Bergsagel, P. Leif, van Rhee, Frits, Janz, Siegfried, Tricot, Guido, Shaughnessy, John D., Zhan, Fenghuang
Published in Cell reports. Medicine (17.10.2023)
Published in Cell reports. Medicine (17.10.2023)
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Journal Article
Cystatin M/E ameliorates bone resorption through increasing osteoclastic cell estrogen influx
Chen, Jin-Ran, Gai, Dongzheng, Caviness, Perry, Lazarenko, Oxana, Chen, Jennifer, Randolph, Christopher, Zhang, Zijun, Cheng, Yan, Sun, Fumou, Xu, Hongwei, Blackburn, Michael, Tricot, Guido, Shaughnessy, John, Zhan, Fenghuang
Published in Research square (06.05.2024)
Published in Research square (06.05.2024)
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