TNF and Increased Intracellular Iron Alter Macrophage Polarization to a Detrimental M1 Phenotype in the Injured Spinal Cord
Kroner, Antje, Greenhalgh, Andrew D., Zarruk, Juan G., Passos dos Santos, Rosmarini, Gaestel, Matthias, David, Samuel
Published in Neuron (Cambridge, Mass.) (03.09.2014)
Published in Neuron (Cambridge, Mass.) (03.09.2014)
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The stress-responsive kinases MAPKAPK2/MAPKAPK3 activate starvation-induced autophagy through Beclin 1 phosphorylation
Wei, Yongjie, An, Zhenyi, Zou, Zhongju, Sumpter, Rhea, Su, Minfei, Zang, Xiao, Sinha, Sangita, Gaestel, Matthias, Levine, Beth
Published in eLife (18.02.2015)
Published in eLife (18.02.2015)
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The RNA-binding protein TTP is a global post-transcriptional regulator of feedback control in inflammation
Tiedje, Christopher, Diaz-Muñoz, Manuel D, Trulley, Philipp, Ahlfors, Helena, Laaß, Kathrin, Blackshear, Perry J, Turner, Martin, Gaestel, Matthias
Published in Nucleic acids research (06.09.2016)
Published in Nucleic acids research (06.09.2016)
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Journal Article
The p38/MK2-driven exchange between tristetraprolin and HuR regulates AU-rich element-dependent translation
Tiedje, Christopher, Ronkina, Natalia, Tehrani, Mohammad, Dhamija, Sonam, Laass, Kathrin, Holtmann, Helmut, Kotlyarov, Alexey, Gaestel, Matthias
Published in PLoS genetics (01.09.2012)
Published in PLoS genetics (01.09.2012)
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The p38-MK2/3 Module Is Critical for IL-33-Induced Signaling and Cytokine Production in Dendritic Cells
Göpfert, Christiane, Andreas, Nico, Weber, Franziska, Häfner, Norman, Yakovleva, Tatiana, Gaestel, Matthias, Kamradt, Thomas, Drube, Sebastian
Published in The Journal of immunology (1950) (01.02.2018)
Published in The Journal of immunology (1950) (01.02.2018)
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Phosphorylation of steroid receptor coactivator-3 (SRC-3) at serine 857 is regulated by the p38MAPK-MK2 axis and affects NF-κB-mediated transcription
Shrestha, Anup, Bruckmueller, Henrike, Kildalsen, Hanne, Kaur, Gurjit, Gaestel, Matthias, Wetting, Hilde Ljones, Mikkola, Ingvild, Seternes, Ole-Morten
Published in Scientific reports (09.07.2020)
Published in Scientific reports (09.07.2020)
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The IL-33-induced p38-/JNK1/2-TNFα axis is antagonized by activation of β-adrenergic-receptors in dendritic cells
Helbig, Christiane, Weber, Franziska, Andreas, Nico, Herdegen, Thomas, Gaestel, Matthias, Kamradt, Thomas, Drube, Sebastian
Published in Scientific reports (18.05.2020)
Published in Scientific reports (18.05.2020)
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Journal Article
Cytokine Storm
Gaestel, Matthias, Nebreda, Angel R, Yaffe, Michael B, Supady, Alexander, Bode, Christoph, Duerschmied, Daniel, Mudd, Philip A, Crawford, Jeremy C, Thomas, Paul G, Fajgenbaum, David C, June, Carl H
Published in The New England journal of medicine (22.04.2021)
Published in The New England journal of medicine (22.04.2021)
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The Role of TTP Phosphorylation in the Regulation of Inflammatory Cytokine Production by MK2/3
Ronkina, Natalia, Shushakova, Nelli, Tiedje, Christopher, Yakovleva, Tatiana, Tollenaere, Maxim A X, Scott, Aaron, Batth, Tanveer Singh, Olsen, Jesper Velgaard, Helmke, Alexandra, Bekker-Jensen, Simon Holst, Clark, Andrew R, Kotlyarov, Alexey, Gaestel, Matthias
Published in The Journal of immunology (1950) (15.10.2019)
Published in The Journal of immunology (1950) (15.10.2019)
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Regulation of Zfp36 by ISGF3 and MK2 restricts the expression of inflammatory cytokines during necroptosis stimulation
Yadav, Sahil, El Hamra, Rayan, Alturki, Norah A, Ariana, Ardeshir, Bhan, Avni, Hurley, Kate, Gaestel, Matthias, Blackshear, Perry J, Blais, Alexandre, Sad, Subash
Published in Cell death & disease (08.08.2024)
Published in Cell death & disease (08.08.2024)
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GIGYF1/2-Driven Cooperation between ZNF598 and TTP in Posttranscriptional Regulation of Inflammatory Signaling
Tollenaere, Maxim A.X., Tiedje, Christopher, Rasmussen, Simon, Nielsen, Julie C., Vind, Anna C., Blasius, Melanie, Batth, Tanveer S., Mailand, Niels, Olsen, Jesper V., Gaestel, Matthias, Bekker-Jensen, Simon
Published in Cell reports (Cambridge) (26.03.2019)
Published in Cell reports (Cambridge) (26.03.2019)
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Genetic deletion of SEPT7 reveals a cell type-specific role of septins in microtubule destabilization for the completion of cytokinesis
Menon, Manoj B, Sawada, Akihiro, Chaturvedi, Anuhar, Mishra, Pooja, Schuster-Gossler, Karin, Galla, Melanie, Schambach, Axel, Gossler, Achim, Förster, Reinhold, Heuser, Michael, Kotlyarov, Alexey, Kinoshita, Makoto, Gaestel, Matthias
Published in PLoS genetics (01.08.2014)
Published in PLoS genetics (01.08.2014)
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NAMPT is essential for the G-CSF-induced myeloid differentiation via a NAD(+)-sirtuin-1-dependent pathway
Skokowa, Julia, Lan, Dan, Thakur, Basant Kumar, Wang, Fei, Gupta, Kshama, Cario, Gunnar, Brechlin, Annette Müller, Schambach, Axel, Hinrichsen, Lars, Meyer, Gustav, Gaestel, Matthias, Stanulla, Martin, Tong, Qiang, Welte, Karl
Published in Nature medicine (01.02.2009)
Published in Nature medicine (01.02.2009)
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Journal Article
Editorial: Emerging Functions of Septins—Volume II
Menon, Manoj B., Gaestel, Matthias
Published in Frontiers in cell and developmental biology (16.06.2022)
Published in Frontiers in cell and developmental biology (16.06.2022)
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MK2/3 Are Pivotal for IL-33-Induced and Mast Cell-Dependent Leukocyte Recruitment and the Resulting Skin Inflammation
Drube, Sebastian, Kraft, Florian, Dudeck, Jan, Müller, Anna-Lena, Weber, Franziska, Göpfert, Christiane, Meininger, Isabel, Beyer, Mandy, Irmler, Ingo, Häfner, Norman, Schütz, Dagmar, Stumm, Ralf, Yakovleva, Tatiana, Gaestel, Matthias, Dudeck, Anne, Kamradt, Thomas
Published in The Journal of immunology (1950) (01.11.2016)
Published in The Journal of immunology (1950) (01.11.2016)
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