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Gadek, T. R., Burdick, D. J., McDowell, R. S., Stanley, M. S., Marsters, J. C., Paris, K. J., Oare, D. A., Reynolds, M. E., Ladner, C., Zioncheck, K. A., Lee, W. P., Gribling, P., Dennis, M. S., Skelton, N. J., Tumas, D. B., Clark, K. R., Keating, S. M., Beresini, M. H., Tilley, J. W., Presta, L. G., Bodary, S. C.
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Published in Science (American Association for the Advancement of Science) (08.02.2002)
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Safety, tolerability, and bioavailability of topical SAR 1118, a novel antagonist of lymphocyte function-associated antigen-1: a phase 1b study
Paskowitz, D M, Nguyen, Q D, Gehlbach, P, Handa, J T, Solomon, S, Stark, W, Shaikh, O, Semba, C, Gadek, T R, Do, D V
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Lipofection: A Highly Efficient, Lipid-Mediated DNA-Transfection Procedure
Felgner, Philip L., Gadek, Thomas R., Holm, Marilyn, Roman, Richard, Chan, Hardy W., Wenz, Michael, Northrop, Jeffrey P., Ringold, Gordon M., Danielsen, Mark
Published in Proceedings of the National Academy of Sciences - PNAS (01.11.1987)
Published in Proceedings of the National Academy of Sciences - PNAS (01.11.1987)
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Preclinical absorption, distribution, metabolism and excretion (ADME) characterization of ICAM1988, an LFA-1/ICAM antagonist, and its prodrug
Khojasteh, S. C., Leipold, D. D., Lai, F., La, H., Baumgardner, M. J., Desino, K. E., Gudmundsson, O. S., Bloedow, D. C., Bodary, S. C., Reynolds, M. E., Gadek, T. R., Kenkare-Mitra, S.
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Published in Xenobiotica (01.03.2008)
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Discovery of small molecule leads in a biotechnology datastream
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Book Review
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Cyclic RGD peptide analogues as antiplatelet antithrombotics
Barker, P L, Bullens, S, Bunting, S, Burdick, D J, Chan, K S, Deisher, T, Eigenbrot, C, Gadek, T R, Gantzos, R, Lipari, M T
Published in Journal of medicinal chemistry (29.05.1992)
Published in Journal of medicinal chemistry (29.05.1992)
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Effect of selective or combined inhibition of integrins alpha(IIb)beta(3) and alpha(v)beta(3) on thrombosis and neointima after oversized porcine coronary angioplasty
Chico, T J, Chamberlain, J, Gunn, J, Arnold, N, Bullens, S L, Gadek, T R, Francis, S E, Bunting, S, Horton, M, Shepherd, L, Lipari, M T, Quan, C, Knolle, J, Stilz, H U, Peyman, A, Crossman, D C
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Published in Circulation (New York, N.Y.) (27.02.2001)
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Structural studies of potent constrained RGD peptides
McDowell, Robert S, Gadek, Thomas R
Published in Journal of the American Chemical Society (01.11.1992)
Published in Journal of the American Chemical Society (01.11.1992)
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alpha(v)beta(3) Antagonists based on a central thiophene scaffold
Peyman, A, Scheunemann, K, Will, D W, Knolle, J, Wehner, V, Breipohl, G, Stilz, H U, Carniato, D, Ruxer, J, Gourvest, J, Auberval, M, Doucet, B, Baron, R, Gaillard, M, Gadek, T R, Bodary, S
Published in Bioorganic & medicinal chemistry letters (06.08.2001)
Published in Bioorganic & medicinal chemistry letters (06.08.2001)
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Structural Determinants of Calcium Signaling by RGD Peptides in Rat Osteoclasts: Integrin-Dependent and -Independent Actions
Shankar, Geetha, Gadek, Tom R., Burdick, Dan J., Davison, Ian, Mason, William T., Horton, Michael A.
Published in Experimental cell research (01.08.1995)
Published in Experimental cell research (01.08.1995)
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Safety, tolerability, and bioavailability of topical SAR 1118, a novel antagonist of lymphocyte function-associated antigen-1: a phase 1 b study
PASKOWITZ, D. M, NGUYEN, Q. D, GEHLBACH, P, HANDA, J. T, SOLOMON, S, STARK, W, SHAIKH, O, SEMBA, C, GADEK, T. R, DO, D. V
Published in Eye (London) (2012)
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Published in Eye (London) (2012)
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Discovery and Development of Potent LFA-1/ICAM-1 Antagonist SAR 1118 as an Ophthalmic Solution for Treating Dry Eye
Zhong, Min, Gadek, Thomas R, Bui, Minna, Shen, Wang, Burnier, John, Barr, Kenneth J, Hanan, Emily J, Oslob, Johan D, Yu, Chul H, Zhu, Jiang, Arkin, Michelle R, Evanchik, Marc J, Flanagan, W. Mike, Hoch, Ute, Hyde, Jennifer, Prabhu, Saileta, Silverman, Jeffrey A, Wright, Jasmin
Published in ACS medicinal chemistry letters (08.03.2012)
Published in ACS medicinal chemistry letters (08.03.2012)
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Preclinical absorption, distributior metabolism and excretion (ADME) characterization of ICAM1988, an LFA-1/ICAM antagonist, and its prodrug
Khojasteh, S C, Leipold, D D, Lai, F, La, H, Baumgardner, MJ, Desino, KE, Gudmundsson, O S, Bloedow, D C, Bodary, S C, Reynolds, ME, Gadek, T R, Kenkare-Mitra, S
Published in Xenobiotica (01.01.2008)
Published in Xenobiotica (01.01.2008)
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RGD mimetics containing a central hydantoin scaffold: alpkha(v)beta3 vs alpha(IIb)beta3 selectivity requirements
Peyman, A, Wehner, V, Knolle, J, Stilz, H U, Breipohl, G, Scheunemann, K H, Carniato, D, Ruxer, J M, Gourvest, J F, Gadek, T R, Bodary, S
Published in Bioorganic & medicinal chemistry letters (17.01.2000)
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Published in Bioorganic & medicinal chemistry letters (17.01.2000)
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