A Dietary Fiber-Deprived Gut Microbiota Degrades the Colonic Mucus Barrier and Enhances Pathogen Susceptibility
Desai, Mahesh S., Seekatz, Anna M., Koropatkin, Nicole M., Kamada, Nobuhiko, Hickey, Christina A., Wolter, Mathis, Pudlo, Nicholas A., Kitamoto, Sho, Terrapon, Nicolas, Muller, Arnaud, Young, Vincent B., Henrissat, Bernard, Wilmes, Paul, Stappenbeck, Thaddeus S., Núñez, Gabriel, Martens, Eric C.
Published in Cell (17.11.2016)
Published in Cell (17.11.2016)
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Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner
Conos, Stephanie A., Chen, Kaiwen W., De Nardo, Dominic, Hara, Hideki, Whitehead, Lachlan, Núñez, Gabriel, Masters, Seth L., Murphy, James M., Schroder, Kate, Vaux, David L., Lawlor, Kate E., Lindqvist, Lisa M., Vince, James E.
Published in Proceedings of the National Academy of Sciences - PNAS (07.02.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (07.02.2017)
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In Vivo Amelioration of Age-Associated Hallmarks by Partial Reprogramming
Ocampo, Alejandro, Reddy, Pradeep, Martinez-Redondo, Paloma, Platero-Luengo, Aida, Hatanaka, Fumiyuki, Hishida, Tomoaki, Li, Mo, Lam, David, Kurita, Masakazu, Beyret, Ergin, Araoka, Toshikazu, Vazquez-Ferrer, Eric, Donoso, David, Roman, Jose Luis, Xu, Jinna, Rodriguez Esteban, Concepcion, Nuñez, Gabriel, Nuñez Delicado, Estrella, Campistol, Josep M., Guillen, Isabel, Guillen, Pedro, Izpisua Belmonte, Juan Carlos
Published in Cell (15.12.2016)
Published in Cell (15.12.2016)
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Th17 Cell Induction by Adhesion of Microbes to Intestinal Epithelial Cells
Atarashi, Koji, Tanoue, Takeshi, Ando, Minoru, Kamada, Nobuhiko, Nagano, Yuji, Narushima, Seiko, Suda, Wataru, Imaoka, Akemi, Setoyama, Hiromi, Nagamori, Takashi, Ishikawa, Eiji, Shima, Tatsuichiro, Hara, Taeko, Kado, Shoichi, Jinnohara, Toshi, Ohno, Hiroshi, Kondo, Takashi, Toyooka, Kiminori, Watanabe, Eiichiro, Yokoyama, Shin-ichiro, Tokoro, Shunji, Mori, Hiroshi, Noguchi, Yurika, Morita, Hidetoshi, Ivanov, Ivaylo I., Sugiyama, Tsuyoshi, Nuñez, Gabriel, Camp, J. Gray, Hattori, Masahira, Umesaki, Yoshinori, Honda, Kenya
Published in Cell (08.10.2015)
Published in Cell (08.10.2015)
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Cytosolic double-stranded RNA activates the NLRP3 inflammasome via MAVS-induced membrane permeabilization and K+ efflux
Franchi, Luigi, Eigenbrod, Tatjana, Muñoz-Planillo, Raúl, Ozkurede, Ulas, Kim, Yun-Gi, Arindam, Chakrabarti, Gale, Jr, Michael, Silverman, Robert H, Colonna, Marco, Akira, Shizuo, Núñez, Gabriel
Published in The Journal of immunology (1950) (15.10.2014)
Published in The Journal of immunology (1950) (15.10.2014)
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Nod2-mediated recognition of the microbiota is critical for mucosal adjuvant activity of cholera toxin
Kim, Donghyun, Kim, Yun-Gi, Seo, Sang-Uk, Kim, Dong-Jae, Kamada, Nobuhiko, Prescott, Dave, Chamaillard, Mathias, Philpott, Dana J, Rosenstiel, Philip, Inohara, Naohiro, Núñez, Gabriel
Published in Nature medicine (01.05.2016)
Published in Nature medicine (01.05.2016)
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Microbial metabolite sensor GPR43 controls severity of experimental GVHD
Fujiwara, Hideaki, Docampo, Melissa D, Riwes, Mary, Peltier, Daniel, Toubai, Tomomi, Henig, Israel, Wu, S Julia, Kim, Stephanie, Taylor, Austin, Brabbs, Stuart, Liu, Chen, Zajac, Cynthia, Oravecz-Wilson, Katherine, Sun, Yaping, Núñez, Gabriel, Levine, John E, van den Brink, Marcel R M, Ferrara, James L M, Reddy, Pavan
Published in Nature communications (10.09.2018)
Published in Nature communications (10.09.2018)
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Microbial Metabolite Signaling Is Required for Systemic Iron Homeostasis
Das, Nupur K., Schwartz, Andrew J., Barthel, Gabrielle, Inohara, Naohiro, Liu, Qing, Sankar, Amanda, Hill, David R., Ma, Xiaoya, Lamberg, Olivia, Schnizlein, Matthew K., Arqués, Juan L., Spence, Jason R., Nunez, Gabriel, Patterson, Andrew D., Sun, Duxin, Young, Vincent B., Shah, Yatrik M.
Published in Cell metabolism (07.01.2020)
Published in Cell metabolism (07.01.2020)
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Distinct Commensals Induce Interleukin-1β via NLRP3 Inflammasome in Inflammatory Monocytes to Promote Intestinal Inflammation in Response to Injury
Seo, Sang-Uk, Kamada, Nobuhiko, Muñoz-Planillo, Raúl, Kim, Yun-Gi, Kim, Donghyun, Koizumi, Yukiko, Hasegawa, Mizuho, Himpsl, Stephanie D., Browne, Hilary P., Lawley, Trevor D., Mobley, Harry L.T., Inohara, Naohiro, Núñez, Gabriel
Published in Immunity (Cambridge, Mass.) (21.04.2015)
Published in Immunity (Cambridge, Mass.) (21.04.2015)
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A green synthesis of copper nanoparticles using native cyclodextrins as stabilizing agents
Suárez-Cerda, Javier, Espinoza-Gómez, Heriberto, Alonso-Núñez, Gabriel, Rivero, Ignacio A., Gochi-Ponce, Yadira, Flores-López, Lucía Z.
Published in Journal of Saudi Chemical Society (01.03.2017)
Published in Journal of Saudi Chemical Society (01.03.2017)
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Humoral Immunity in the Gut Selectively Targets Phenotypically Virulent Attaching-and-Effacing Bacteria for Intraluminal Elimination
Kamada, Nobuhiko, Sakamoto, Kei, Seo, Sang-Uk, Zeng, Melody Y., Kim, Yun-Gi, Cascalho, Marilia, Vallance, Bruce A., Puente, José L., Núñez, Gabriel
Published in Cell host & microbe (13.05.2015)
Published in Cell host & microbe (13.05.2015)
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A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases
Coll, Rebecca C, Robertson, Avril A B, Chae, Jae Jin, Higgins, Sarah C, Muñoz-Planillo, Raúl, Inserra, Marco C, Vetter, Irina, Dungan, Lara S, Monks, Brian G, Stutz, Andrea, Croker, Daniel E, Butler, Mark S, Haneklaus, Moritz, Sutton, Caroline E, Núñez, Gabriel, Latz, Eicke, Kastner, Daniel L, Mills, Kingston H G, Masters, Seth L, Schroder, Kate, Cooper, Matthew A, O'Neill, Luke A J
Published in Nature medicine (01.03.2015)
Published in Nature medicine (01.03.2015)
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Study of the green synthesis of silver nanoparticles using a natural extract of dark or white Salvia hispanica L. seeds and their antibacterial application
Hernández-Morales, Liliana, Espinoza-Gómez, Heriberto, Flores-López, Lucía Z., Sotelo-Barrera, Erika Lis, Núñez-Rivera, Alfredo, Cadena-Nava, Rubén Darío, Alonso-Núñez, Gabriel, Espinoza, Karla Alejandra
Published in Applied surface science (30.09.2019)
Published in Applied surface science (30.09.2019)
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The Nod2 Sensor Promotes Intestinal Pathogen Eradication via the Chemokine CCL2-Dependent Recruitment of Inflammatory Monocytes
Kim, Yun-Gi, Kamada, Nobuhiko, Shaw, Michael H., Warner, Neil, Chen, Grace Y., Franchi, Luigi, Núñez, Gabriel
Published in Immunity (Cambridge, Mass.) (27.05.2011)
Published in Immunity (Cambridge, Mass.) (27.05.2011)
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Shigella IpaH7.8 E3 ubiquitin ligase targets glomulin and activates inflammasomes to demolish macrophages
Suzuki, Shiho, Mimuro, Hitomi, Kim, Minsoo, Ogawa, Michinaga, Ashida, Hiroshi, Toyotome, Takahito, Franchi, Luigi, Suzuki, Masato, Sanada, Takahito, Suzuki, Toshihiko, Tsutsui, Hiroko, Núñez, Gabriel, Sasakawa, Chihiro
Published in Proceedings of the National Academy of Sciences - PNAS (07.10.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (07.10.2014)
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Staphylococcus Agr virulence is critical for epidermal colonization and associates with atopic dermatitis development
Nakamura, Yuumi, Takahashi, Hiroki, Takaya, Akiko, Inoue, Yuzaburo, Katayama, Yuki, Kusuya, Yoko, Shoji, Tatsuma, Takada, Sanami, Nakagawa, Seitaro, Oguma, Rena, Saito, Nobuko, Ozawa, Naoko, Nakano, Taiji, Yamaide, Fumiya, Dissanayake, Eishika, Suzuki, Shuichi, Villaruz, Amer, Varadarajan, Saranyaraajan, Matsumoto, Masanori, Kobayashi, Tomoko, Kono, Michihiro, Sato, Yasunori, Akiyama, Masashi, Otto, Michael, Matsue, Hiroyuki, Núñez, Gabriel, Shimojo, Naoki
Published in Science translational medicine (08.07.2020)
Published in Science translational medicine (08.07.2020)
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Neonatal acquisition of Clostridia species protects against colonization by bacterial pathogens
Kim, Yun-Gi, Sakamoto, Kei, Seo, Sang-Uk, Pickard, Joseph M., Gillilland, Merritt G., Pudlo, Nicholas A., Hoostal, Matthew, Li, Xue, Wang, Thomas D., Feehley, Taylor, Stefka, Andrew T., Schmidt, Thomas M., Martens, Eric C., Fukuda, Shinji, Inohara, Naohiro, Nagler, Cathryn R., Núñez, Gabriel
Published in Science (American Association for the Advancement of Science) (21.04.2017)
Published in Science (American Association for the Advancement of Science) (21.04.2017)
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Neutrophils Restrict Tumor-Associated Microbiota to Reduce Growth and Invasion of Colon Tumors in Mice
Triner, Daniel, Devenport, Samantha N., Ramakrishnan, Sadeesh K., Ma, Xiaoya, Frieler, Ryan A., Greenson, Joel K., Inohara, Naohiro, Nunez, Gabriel, Colacino, Justin A., Mortensen, Richard M., Shah, Yatrik M.
Published in Gastroenterology (New York, N.Y. 1943) (01.04.2019)
Published in Gastroenterology (New York, N.Y. 1943) (01.04.2019)
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Human Umbilical Cord Blood Mesenchymal Stem Cells Reduce Colitis in Mice by Activating NOD2 Signaling to COX2
Kim, Hyung–Sik, Shin, Tae–Hoon, Lee, Byung–Chul, Yu, Kyung–Rok, Seo, Yoojin, Lee, Seunghee, Seo, Min–Soo, Hong, In–Sun, Choi, Soon Won, Seo, Kwang–Won, Núñez, Gabriel, Park, Jong–Hwan, Kang, Kyung–Sun
Published in Gastroenterology (New York, N.Y. 1943) (01.12.2013)
Published in Gastroenterology (New York, N.Y. 1943) (01.12.2013)
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