MiR-135 suppresses glycolysis and promotes pancreatic cancer cell adaptation to metabolic stress by targeting phosphofructokinase-1
Yang, Ying, Ishak Gabra, Mari B., Hanse, Eric A., Lowman, Xazmin H., Tran, Thai Q., Li, Haiqing, Milman, Neta, Liu, Juan, Reid, Michael A., Locasale, Jason W., Gil, Ziv, Kong, Mei
Published in Nature communications (18.02.2019)
Published in Nature communications (18.02.2019)
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Dietary glutamine supplementation suppresses epigenetically-activated oncogenic pathways to inhibit melanoma tumour growth
Ishak Gabra, Mari B., Yang, Ying, Li, Haiqing, Senapati, Parijat, Hanse, Eric A., Lowman, Xazmin H., Tran, Thai Q., Zhang, Lishi, Doan, Linda T., Xu, Xiangdong, Schones, Dustin E., Fruman, David A., Kong, Mei
Published in Nature communications (03.07.2020)
Published in Nature communications (03.07.2020)
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Journal Article
Glutamine deficiency induces DNA alkylation damage and sensitizes cancer cells to alkylating agents through inhibition of ALKBH enzymes
Tran, Thai Q, Ishak Gabra, Mari B, Lowman, Xazmin H, Yang, Ying, Reid, Michael A, Pan, Min, O'Connor, Timothy R, Kong, Mei
Published in PLoS biology (06.11.2017)
Published in PLoS biology (06.11.2017)
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Transcriptional diversity and bioenergetic shift in human breast cancer metastasis revealed by single-cell RNA sequencing
Davis, Ryan T., Blake, Kerrigan, Ma, Dennis, Gabra, Mari B. Ishak, Hernandez, Grace A., Phung, Anh T., Yang, Ying, Maurer, Dustin, Lefebvre, Austin E. Y. T., Alshetaiwi, Hamad, Xiao, Zhengtao, Liu, Juan, Locasale, Jason W., Digman, Michelle A., Mjolsness, Eric, Kong, Mei, Werb, Zena, Lawson, Devon A.
Published in Nature cell biology (01.03.2020)
Published in Nature cell biology (01.03.2020)
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α-Ketoglutarate attenuates Wnt signaling and drives differentiation in colorectal cancer
Tran, Thai Q, Hanse, Eric A, Habowski, Amber N, Li, Haiqing, Ishak Gabra, Mari B, Yang, Ying, Lowman, Xazmin H, Ooi, Amelia M, Liao, Shu Y, Edwards, Robert A, Waterman, Marian L, Kong, Mei
Published in Nature cancer (01.03.2020)
Published in Nature cancer (01.03.2020)
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Journal Article
IKKβ promotes metabolic adaptation to glutamine deprivation via phosphorylation and inhibition of PFKFB3
Reid, Michael A, Lowman, Xazmin H, Pan, Min, Tran, Thai Q, Warmoes, Marc O, Ishak Gabra, Mari B, Yang, Ying, Locasale, Jason W, Kong, Mei
Published in Genes & development (15.08.2016)
Published in Genes & development (15.08.2016)
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The B56α subunit of PP2A is necessary for mesenchymal stem cell commitment to adipocyte
Hanse, Eric A, Pan, Min, Liu, Wenzhu, Yang, Ying, Ishak Gabra, Mari B, Tran, Thai Q, Lowman, Xazmin H, Ruiz, Bryan, Wang, Qiong A, Kong, Mei
Published in EMBO reports (04.08.2021)
Published in EMBO reports (04.08.2021)
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IKKβ activates p53 to promote cancer cell adaptation to glutamine deprivation
Ishak Gabra, Mari B., Yang, Ying, Lowman, Xazmin H., Reid, Michael A., Tran, Thai Q., Kong, Mei
Published in Oncogenesis (New York, NY) (26.11.2018)
Published in Oncogenesis (New York, NY) (26.11.2018)
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Metabolic adaptations to glutamine deprivation in pancreatic cancer
Yang, Ying, Ishak Gabra, Mari B., Kong, Mei
Published in JoLS, Journal of Life Sciences (01.09.2019)
Published in JoLS, Journal of Life Sciences (01.09.2019)
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