Major glucuronide metabolites of testosterone are primarily transported by MRP2 and MRP3 in human liver, intestine and kidney
Li, Cindy Yanfei, Basit, Abdul, Gupta, Anshul, Gáborik, Zsuzsanna, Kis, Emese, Prasad, Bhagwat
Published in The Journal of steroid biochemistry and molecular biology (01.07.2019)
Published in The Journal of steroid biochemistry and molecular biology (01.07.2019)
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Journal Article
Quantitative Investigation of Irinotecan Metabolism, Transport, and Gut Microbiome Activation
Parvez, Md Masud, Basit, Abdul, Jariwala, Parth B, Gáborik, Zsuzsanna, Kis, Emese, Heyward, Scott, Redinbo, Matthew R, Prasad, Bhagwat
Published in Drug metabolism and disposition (01.08.2021)
Published in Drug metabolism and disposition (01.08.2021)
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Journal Article
Successful Prediction of Human Hepatic Concentrations of Transported Drugs Using the Proteomics-Informed Relative Expression Factor Approach
Yin, Mengyue, Balhara, Ankit, Marie, Solène, Tournier, Nicolas, Gáborik, Zsuzsanna, Unadkat, Jashvant D
Published in Clinical pharmacology and therapeutics (01.03.2024)
Published in Clinical pharmacology and therapeutics (01.03.2024)
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Journal Article
P228 - Assay calibration to refine prediction of OATP1B1/1B3 mediated drug-drug interactions (DDI) based on in vitro uptake transport assay data
Kovacs, Peter, Sane, Rucha, Kathy Cheung, Kit Wun, Kis, Emese, Plise, Emile, Gaborik, Zsuzsanna
Published in Drug metabolism and pharmacokinetics (2020)
Published in Drug metabolism and pharmacokinetics (2020)
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Journal Article
Intracellular Metabolomics Identifies Efflux Transporter Inhibitors in a Routine Caco-2 Cell Permeability Assay-Biological Implications
Naseem, Afia, Pal, Akos, Gowan, Sharon, Asad, Yasmin, Donovan, Adam, Temesszentandrási-Ambrus, Csilla, Kis, Emese, Gaborik, Zsuzsanna, Bhalay, Gurdip, Raynaud, Florence
Published in Cells (Basel, Switzerland) (01.10.2022)
Published in Cells (Basel, Switzerland) (01.10.2022)
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Journal Article
Intracellular trafficking of hormone receptors
Gáborik, Zsuzsanna, Hunyady, László
Published in Trends in endocrinology and metabolism (01.08.2004)
Published in Trends in endocrinology and metabolism (01.08.2004)
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Journal Article
The Inhibitor Preincubation Effect Is Universal to SLC Transporter Assays and Is Only Partially Eliminated in the Presence of Extracellular Protein
Tátrai, Péter, Temesszentandrási-Ambrus, Csilla, Varga, Tamás, Gáborik, Zsuzsanna
Published in Drug metabolism and disposition (01.08.2023)
Published in Drug metabolism and disposition (01.08.2023)
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Journal Article
A Systematic In Vitro Investigation of the Inhibitor Preincubation Effect on Multiple Classes of Clinically Relevant Transporters
Tátrai, Péter, Schweigler, Patrick, Poller, Birk, Domange, Norbert, de Wilde, Roelof, Hanna, Imad, Gáborik, Zsuzsanna, Huth, Felix
Published in Drug metabolism and disposition (01.07.2019)
Published in Drug metabolism and disposition (01.07.2019)
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Journal Article
A Unique In Vitro Assay to Investigate ABCB4 Transport Function
Temesszentandrási-Ambrus, Csilla, Nagy, Gábor, Bui, Annamária, Gáborik, Zsuzsanna
Published in International journal of molecular sciences (24.02.2023)
Published in International journal of molecular sciences (24.02.2023)
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Journal Article
Interactions of the Anti-SARS-CoV-2 Agents Molnupiravir and Nirmatrelvir/Paxlovid with Human Drug Transporters
Bakos, Éva, Temesszentandrási-Ambrus, Csilla, Özvegy-Laczka, Csilla, Gáborik, Zsuzsanna, Sarkadi, Balázs, Telbisz, Ágnes
Published in International journal of molecular sciences (01.07.2023)
Published in International journal of molecular sciences (01.07.2023)
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Journal Article
Pitfalls in Predicting Hepatobiliary Drug Transport Using Human Sandwich-Cultured Hepatocytes
Kumar, Vineet, Li, Cindy Yanfei, Ishida, Kazuya, Kis, Emese, Gáborik, Zsuzsanna, Unadkat, Jashvant D.
Published in The AAPS journal (17.08.2020)
Published in The AAPS journal (17.08.2020)
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Journal Article
Calibrating the In Vitro-In Vivo Correlation for OATP-Mediated Drug-Drug Interactions with Rosuvastatin Using Static and PBPK Models
Sane, Rucha, Cheung, Kit Wun Kathy, Kovács, Péter, Farasyn, Taleah, Li, Ruina, Bui, Annamaria, Musib, Luna, Kis, Emese, Plise, Emile, Gáborik, Zsuzsanna
Published in Drug metabolism and disposition (01.12.2020)
Published in Drug metabolism and disposition (01.12.2020)
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Journal Article
Translatability of in vitro Inhibition Potency to in vivo P-Glycoprotein Mediated Drug Interaction Risk
Lazzaro, Sarah, West, Mark A., Eatemadpour, Soraya, Feng, Bo, Varma, Manthena V.S., Rodrigues, A. David, Temesszentandrási-Ambrus, Csilla, Kovács-Hajdu, Péter, Nerada, Zsuzsanna, Gáborik, Zsuzsanna, Costales, Chester
Published in Journal of pharmaceutical sciences (01.06.2023)
Published in Journal of pharmaceutical sciences (01.06.2023)
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Journal Article
Applicability of MDR1 Overexpressing Abcb1KO-MDCKII Cell Lines for Investigating In Vitro Species Differences and Brain Penetration Prediction
Sóskuti, Emőke, Szilvásy, Nóra, Temesszentandrási-Ambrus, Csilla, Urbán, Zoltán, Csíkvári, Olivér, Szabó, Zoltán, Kecskeméti, Gábor, Pusztai, Éva, Gáborik, Zsuzsanna
Published in Pharmaceutics (29.05.2024)
Published in Pharmaceutics (29.05.2024)
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Journal Article
Identification of reversible OATP1B1 and time-dependent CYP3A4 inhibition as the major risk factors for drug-induced cholestasis (DIC)
Kastrinou-Lampou, Vlasia, Rodríguez-Pérez, Raquel, Poller, Birk, Huth, Felix, Gáborik, Zsuzsanna, Mártonné-Tóth, Beáta, Temesszentandrási-Ambrus, Csilla, Schadt, Heiko S., Kullak-Ublick, Gerd A., Arand, Michael, Camenisch, Gian
Published in Archives of toxicology (01.10.2024)
Published in Archives of toxicology (01.10.2024)
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Journal Article
Membrane Transporters in Physiological Barriers of Pharmacological Importance
Nagy, Ildikó, Tóth, Beáta, Gáborik, Zsuzsanna, Erdo, Franciska, Krajcsi, Péter
Published in Current pharmaceutical design (01.01.2016)
Published in Current pharmaceutical design (01.01.2016)
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Journal Article
The Role of a Conserved Region of the Second Intracellular Loop in AT1 Angiotensin Receptor Activation and Signaling
Gáborik, Zsuzsanna, Jagadeesh, Gowraganahalli, Zhang, Meng, Spät, András, Catt, Kevin J, Hunyady, László
Published in Endocrinology (Philadelphia) (01.06.2003)
Published in Endocrinology (Philadelphia) (01.06.2003)
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Journal Article
Differential PI 3-kinase dependence of early and late phases of recycling of the internalized AT1 angiotensin receptor
Hunyady, Laszlo, Baukal, Albert J, Gaborik, Zsuzsanna, Olivares-Reyes, Jesus A, Bor, Marta, Szaszak, Marta, Lodge, Robert, Catt, Kevin J, Balla, Tamas
Published in The Journal of cell biology (24.06.2002)
Published in The Journal of cell biology (24.06.2002)
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Journal Article
P162 - Further characterization of hepatopac – non-targeted metabolite-profiling of 7 chemicals including slow clearance chemicals and metabolism-mediated toxicity
Lee, Mi-Young, Cubberley, Richard, Gáborik, Zsuzsanna, Molnár, Bálint, Herédi-Szabó, Krisztina, Kalapos-Kovács, Bernadett
Published in Drug metabolism and pharmacokinetics (2020)
Published in Drug metabolism and pharmacokinetics (2020)
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