A whole‐genome scan for Artemisinin cytotoxicity reveals a novel therapy for human brain tumors
Taubenschmid‐Stowers, Jasmin, Orthofer, Michael, Laemmerer, Anna, Krauditsch, Christian, Rózsová, Marianna, Studer, Christian, Lötsch, Daniela, Gojo, Johannes, Gabler, Lisa, Dyczynski, Matheus, Efferth, Thomas, Hagelkruys, Astrid, Widhalm, Georg, Peyrl, Andreas, Spiegl‐Kreinecker, Sabine, Hoepfner, Dominic, Bian, Shan, Berger, Walter, Knoblich, Juergen A, Elling, Ulrich, Horn, Moritz, Penninger, Josef M
Published in EMBO molecular medicine (08.03.2023)
Published in EMBO molecular medicine (08.03.2023)
Get full text
Journal Article
Intrinsic fluorescence of the clinically approved multikinase inhibitor nintedanib reveals lysosomal sequestration as resistance mechanism in FGFR-driven lung cancer
Englinger, Bernhard, Kallus, Sebastian, Senkiv, Julia, Heilos, Daniela, Gabler, Lisa, van Schoonhoven, Sushilla, Terenzi, Alessio, Moser, Patrick, Pirker, Christine, Timelthaler, Gerald, Jäger, Walter, Kowol, Christian R, Heffeter, Petra, Grusch, Michael, Berger, Walter
Published in Journal of experimental & clinical cancer research (07.09.2017)
Published in Journal of experimental & clinical cancer research (07.09.2017)
Get full text
Journal Article
p53 Loss Mediates Hypersensitivity to ETS Transcription Factor Inhibition Based on PARylation-Mediated Cell Death Induction
Dinhof, Carina, Pirker, Christine, Kroiss, Philipp, Kirchhofer, Dominik, Gabler, Lisa, Gojo, Johannes, Lötsch-Gojo, Daniela, Stojanovic, Mirjana, Timelthaler, Gerald, Ferk, Franziska, Knasmüller, Siegfried, Reisecker, Johannes, Spiegl-Kreinecker, Sabine, Birner, Peter, Preusser, Matthias, Berger, Walter
Published in Cancers (30.10.2020)
Published in Cancers (30.10.2020)
Get full text
Journal Article
Fibroblast growth factor receptor 4 promotes glioblastoma progression: a central role of integrin-mediated cell invasiveness
Gabler, Lisa, Jaunecker, Carola Nadine, Katz, Sonja, van Schoonhoven, Sushilla, Englinger, Bernhard, Pirker, Christine, Mohr, Thomas, Vician, Petra, Stojanovic, Mirjana, Woitzuck, Valentin, Laemmerer, Anna, Kirchhofer, Dominik, Mayr, Lisa, LaFranca, Mery, Erhart, Friedrich, Grissenberger, Sarah, Wenninger-Weinzierl, Andrea, Sturtzel, Caterina, Kiesel, Barbara, Lang, Alexandra, Marian, Brigitte, Grasl-Kraupp, Bettina, Distel, Martin, Schüler, Julia, Gojo, Johannes, Grusch, Michael, Spiegl-Kreinecker, Sabine, Donoghue, Daniel J, Lötsch, Daniela, Berger, Walter
Published in Acta neuropathologica communications (28.04.2022)
Published in Acta neuropathologica communications (28.04.2022)
Get full text
Journal Article
Cerebrospinal Fluid Penetration and Combination Therapy of Entrectinib for Disseminated ROS1/NTRK -Fusion Positive Pediatric High-Grade Glioma
Mayr, Lisa, Guntner, Armin S, Madlener, Sibylle, Schmook, Maria T, Peyrl, Andreas, Azizi, Amedeo A, Dieckmann, Karin, Reisinger, Dominik, Stepien, Natalia M, Schramm, Kathrin, Laemmerer, Anna, Jones, David T W, Ecker, Jonas, Sahm, Felix, Milde, Till, Pajtler, Kristian W, Blattner-Johnson, Mirjam, Strbac, Miroslav, Dorfer, Christian, Czech, Thomas, Kirchhofer, Dominik, Gabler, Lisa, Berger, Walter, Haberler, Christine, Müllauer, Leonhard, Buchberger, Wolfgang, Slavc, Irene, Lötsch-Gojo, Daniela, Gojo, Johannes
Published in Journal of personalized medicine (18.12.2020)
Published in Journal of personalized medicine (18.12.2020)
Get full text
Journal Article
Lysosomal Sequestration Impairs the Activity of the Preclinical FGFR Inhibitor PD173074
Englinger, Bernhard, Kallus, Sebastian, Senkiv, Julia, Laemmerer, Anna, Moser, Patrick, Gabler, Lisa, Groza, Diana, Kowol, Christian R, Heffeter, Petra, Grusch, Michael, Berger, Walter
Published in Cells (Basel, Switzerland) (08.12.2018)
Published in Cells (Basel, Switzerland) (08.12.2018)
Get full text
Journal Article
NFS-20. DECIPHERING CELLULAR CROSSTALK IN PERIPHERAL NERVOUS SYSTEM TUMORS ASSOCIATED WITH NEUROFIBROMATOSIS TYPE 1 THROUGH SINGLE-CELL RNA SEQUENCING
Freund, Julia, Robl, Bernhard, Gabler, Lisa, Machreich, Sarah, Madlener, Sibylle, Baumgartner, Alicia, Lötsch-Gojo, Daniela, Azizi, Amedeo, Gojo, Johannes
Published in Neuro-oncology (Charlottesville, Va.) (18.06.2024)
Published in Neuro-oncology (Charlottesville, Va.) (18.06.2024)
Get full text
Journal Article
EPCO-45. CELLULAR HIERARCHIES OF ETMR ARE SHAPED BY ONCOGENIC MICRORNAS AND RECEPTOR-LIGAND INTERACTIONS
Gabler, Lisa, Beck, Alexander, Cruzeiro, Gustavo, Lambo, Sander, Englinger, Bernhard, Shaw, McKenzie L, Hack, Olivia, Chi, Susan, Alexandrescu, Sanda, Gojo, Johannes, Kool, Marcel, Hovestadt, Volker, Filbin, Mariella
Published in Neuro-oncology (Charlottesville, Va.) (10.11.2023)
Published in Neuro-oncology (Charlottesville, Va.) (10.11.2023)
Get full text
Journal Article
MEDB-82. Exploring cell-cell communication networks in medulloblastoma using single-cell genomics
Gabler, Lisa, Gojo, Johannes, Smith, Kyle S, Bihannic, Laure, Filbin, Mariella G, Northcott, Paul A, Berger, Walter, Hovestadt, Volker
Published in Neuro-oncology (Charlottesville, Va.) (03.06.2022)
Published in Neuro-oncology (Charlottesville, Va.) (03.06.2022)
Get full text
Journal Article
HGG-08. COMBINATORIAL ACTIVITY OF CDK4/6-INHIBITORS AND TRAMETINIB IN PEDIATRIC HIGH-GRADE GLIOMA WITH BRAFV600E MUTATION AND HOMOZYGOUS CDKN2A DELETION
Mayr, Lisa, Mager, Leah, Gabler, Lisa, Madlener, Sibylle, Berger, Julia, Kirchhofer, Dominik, Lämmerer, Anna, Bruckner, Katharina, Lötsch, Daniela, Berger, Walter, Gojo, Johannes
Published in Neuro-oncology (Charlottesville, Va.) (12.06.2023)
Published in Neuro-oncology (Charlottesville, Va.) (12.06.2023)
Get full text
Journal Article
EPEN-12. EZHIP IMPACTS CELLULAR DIFFERENTIATION IN POSTERIOR FOSSA GROUP A EPENDYMOMA
Jaunecker, Carola, Jenseit, Anne, Zehetbauer, Theresa, Stepien, Natalia, Wang, Shanzheng, Bruckner, Katharina, Hübner, Jens-Martin, Gabler, Lisa, Lang, Alexandra, Madlener, Sibylle, Mager, Leah, Haberler, Christine, Berger, Walter, Dorfer, Christian, Filbin, Mariella, Kool, Marcel, Gojo, Johannes, Lötsch-Gojo, Daniela
Published in Neuro-oncology (Charlottesville, Va.) (18.06.2024)
Published in Neuro-oncology (Charlottesville, Va.) (18.06.2024)
Get full text
Journal Article
HGG-15. SYNERGISTIC EFFECTS OF COMBINED MEK/CDK4/6 INHIBITOR TREATMENT ON BRAFV600E POSITIVE HIGH-GRADE GLIOMA
Mayr, Lisa, Mager, Leah, Gabler, Lisa, Madlener, Sibylle, Kirchhofer, Dominik, Lämmerer, Anna, Bruckner, Katharina, Lang, Alexandra, Walter, Romina, Schueler, Julia, Peyrl, Andreas, Azizi, Amedeo A, Dorfer, Christian, Haberler, Christine, Müllauer, Leonhard, Berger, Walter, Lötsch-Gojo, Daniela, Gojo, Johannes
Published in Neuro-oncology (Charlottesville, Va.) (18.06.2024)
Published in Neuro-oncology (Charlottesville, Va.) (18.06.2024)
Get full text
Journal Article
ETMR-11. Transcriptional changes upon knockdown of alteredBCOR/BCORL1 transcripts in preclinical models of CNS embryonal tumors with BCOR-related alterations
Piontek, Martin, Kirchhofer, Dominik, Gabler, Lisa, Lötsch-Gojo, Daniela, Pirker, Christine, Schmitt-Hoffner, Felix, Jaunecker, Carola N, Kool, Marcel, Berger, Walter, Gojo, Johannes
Published in Neuro-oncology (Charlottesville, Va.) (03.06.2022)
Published in Neuro-oncology (Charlottesville, Va.) (03.06.2022)
Get full text
Journal Article
ETMR-11. Transcriptional changes upon knockdown of altered BCOR/BCORL1 transcripts in preclinical models of CNS embryonal tumors with BCOR-related alterations
Piontek, Martin, Kirchhofer, Dominik, Gabler, Lisa, Lötsch-Gojo, Daniela, Pirker, Christine, Schmitt-Hoffner, Felix, Jaunecker, Carola N, Kool, Marcel, Berger, Walter, Gojo, Johannes
Published in Neuro-oncology (Charlottesville, Va.) (03.06.2022)
Published in Neuro-oncology (Charlottesville, Va.) (03.06.2022)
Get full text
Journal Article
EPEN-11. CHARACTERIZATION OF THE SPATIAL ARCHITECTURE OF INTRATUMORAL CELL STATES IN PEDIATRIC HIGH-RISK EPENDYMOMA
Bruckner, Katharina, Madlener, Sibylle, Biagi Junior, Carlos A O, Gabler, Lisa, Senfter, Daniel, Jeong, Daeun, Jiang, Li, Englinger, Bernhard, Jaunecker, Carola, Bilban, Martin, Haberler, Christine, Dorfer, Christian, Rössler, Karl, Kool, Marcel, Berger, Walter, Filbin, Mariella G, Lötsch-Gojo, Daniela, Gojo, Johannes
Published in Neuro-oncology (Charlottesville, Va.) (12.06.2023)
Published in Neuro-oncology (Charlottesville, Va.) (12.06.2023)
Get full text
Journal Article
The tyrosine kinase inhibitor Nintedanib induces lysosomal dysfunctionality: role of protonation-dependent crystallization processes
Mosca, Elena, Federa, Anja, Pirker, Christine, Schosserer, Markus, Liendl, Lisa, Eckhard, Margret, Sombke, Andy, Dömötör, Orsolya, Kirchhofer, Dominik, Timelthaler, Gerald, Baier, Dina, Gurschka, Patrizia, Gabler, Lisa, Reithofer, Michael, Chin, Jia Min, Elsayad, Kareem, Englinger, Bernhard, Tahir, Ammar, Kowol, Christian R., Berger, Walter
Published in Chemico-biological interactions (14.09.2024)
Published in Chemico-biological interactions (14.09.2024)
Get full text
Journal Article
Lipid droplet‐mediated scavenging as novel intrinsic and adaptive resistance factor against the multikinase inhibitor ponatinib
Englinger, Bernhard, Laemmerer, Anna, Moser, Patrick, Kallus, Sebastian, Röhrl, Clemens, Pirker, Christine, Baier, Dina, Mohr, Thomas, Niederstaetter, Laura, Meier‐Menches, Samuel M., Gerner, Christopher, Gabler, Lisa, Gojo, Johannes, Timelthaler, Gerald, Senkiv, Julia, Jäger, Walter, Kowol, Christian R., Heffeter, Petra, Berger, Walter
Published in International journal of cancer (15.09.2020)
Published in International journal of cancer (15.09.2020)
Get full text
Journal Article
Telomerase Reverse Transcriptase Promoter Mutations Identify a Genomically Defined and Highly Aggressive Human Pleural Mesothelioma Subgroup
Pirker, Christine, Bilecz, Agnes, Grusch, Michael, Mohr, Thomas, Heidenreich, Barbara, Laszlo, Viktoria, Stockhammer, Paul, Lötsch-Gojo, Daniela, Gojo, Johannes, Gabler, Lisa, Spiegl-Kreinecker, Sabine, Dome, Balazs, Steindl, Ariane, Klikovits, Thomas, Hoda, Mir Alireza, Jakopovic, Marko, Samarzija, Miroslav, Mohorcic, Katja, Kern, Izidor, Kiesel, Barbara, Brcic, Luka, Oberndorfer, Felicitas, Müllauer, Leonhard, Klepetko, Walter, Schmidt, Wolfgang M, Kumar, Rajiv, Hegedus, Balazs, Berger, Walter
Published in Clinical cancer research (15.07.2020)
Published in Clinical cancer research (15.07.2020)
Get full text
Journal Article
CSIG-30. TARGETING TELOMERASE VIA MEK INHIBITION IN AGGRESSIVE TERT PROMOTER MUTATED BRAIN TUMORS
Lötsch-Gojo, Daniela, Gabler, Lisa, Jaunecker, Carola, Fürnweger, Kerstin, Bruckner, Katharina, Mayr, Lisa, Madlener, Sibylle, Kirchhofer, Dominik, Spiegl-Kreinecker, Sabine, Roessler, Karl, Berger, Walter, Gojo, Johannes
Published in Neuro-oncology (Charlottesville, Va.) (12.11.2021)
Published in Neuro-oncology (Charlottesville, Va.) (12.11.2021)
Get full text
Journal Article
ETMR-19.BCOR/L1-ALTERATIONS REWIRE HISTONE REGULATION TO INDUCE ONCOGENIC PATHWAYS IN PEDIATRIC CENTRAL NERVOUS SYSTEM TUMORS
Bruckner, Katharina, Lötsch-Gojo, Daniela, Gabler, Lisa, Wang, Shanzheng, Kirchhofer, Dominik, Labelle, Jenna, Madlener, Sibylle, Senfter, Daniel, Schmitt-Hoffner, Felix, Federico, Aniello, Koster, Jan, Dorfer, Christian, Tauziède-Espariat, Arnault, Pahnke, Jens, Hovestadt, Volker, Beck, Alexander, Schueler, Julia, Haberler, Christine, Berger, Walter, Filbin, Mariella G, Kool, Marcel, Gojo, Johannes
Published in Neuro-oncology (Charlottesville, Va.) (18.06.2024)
Published in Neuro-oncology (Charlottesville, Va.) (18.06.2024)
Get full text
Journal Article