Improving the secretory capacity of Chinese hamster ovary cells by ectopic expression of effector genes: Lessons learned and future directions
Hansen, Henning Gram, Pristovšek, Nuša, Kildegaard, Helene Faustrup, Lee, Gyun Min
Published in Biotechnology advances (01.01.2017)
Published in Biotechnology advances (01.01.2017)
Get full text
Journal Article
Genome-scale reconstructions of the mammalian secretory pathway predict metabolic costs and limitations of protein secretion
Gutierrez, Jahir M., Feizi, Amir, Li, Shangzhong, Kallehauge, Thomas B., Hefzi, Hooman, Grav, Lise M., Ley, Daniel, Baycin Hizal, Deniz, Betenbaugh, Michael J., Voldborg, Bjorn, Faustrup Kildegaard, Helene, Min Lee, Gyun, Palsson, Bernhard O., Nielsen, Jens, Lewis, Nathan E.
Published in Nature communications (02.01.2020)
Published in Nature communications (02.01.2020)
Get full text
Journal Article
Accelerated homology-directed targeted integration of transgenes in Chinese hamster ovary cells via CRISPR/Cas9 and fluorescent enrichment
Lee, Jae Seong, Grav, Lise Marie, Pedersen, Lasse Ebdrup, Lee, Gyun Min, Kildegaard, Helene Faustrup
Published in Biotechnology and bioengineering (01.11.2016)
Published in Biotechnology and bioengineering (01.11.2016)
Get full text
Journal Article
Multiplex secretome engineering enhances recombinant protein production and purity
Kol, Stefan, Ley, Daniel, Wulff, Tune, Decker, Marianne, Arnsdorf, Johnny, Schoffelen, Sanne, Hansen, Anders Holmgaard, Jensen, Tanja Lyholm, Gutierrez, Jahir M., Chiang, Austin W. T., Masson, Helen O., Palsson, Bernhard O., Voldborg, Bjørn G., Pedersen, Lasse Ebdrup, Kildegaard, Helene Faustrup, Lee, Gyun Min, Lewis, Nathan E.
Published in Nature communications (20.04.2020)
Published in Nature communications (20.04.2020)
Get full text
Journal Article
Understanding of decreased sialylation of Fc‐fusion protein in hyperosmotic recombinant Chinese hamster ovary cell culture: N‐glycosylation gene expression and N‐linked glycan antennary profile
Lee, Jong Hyun, Jeong, Yeong Ran, Kim, Yeon‐Gu, Lee, Gyun Min
Published in Biotechnology and bioengineering (01.08.2017)
Published in Biotechnology and bioengineering (01.08.2017)
Get full text
Journal Article
Amplification of EBNA-1 through a single-plasmid vector-based gene amplification system in HEK293 cells as an efficient transient gene expression system
Park, Sun-Hye, Park, Jong-Ho, Lee, Joo-Hyoung, Lee, Hoon-Min, Kang, Yeon-Ju, Lee, Eun-Ji, Shin, Seunghyeon, Lee, Gyun Min, Kim, Yeon-Gu
Published in Applied microbiology and biotechnology (2021)
Published in Applied microbiology and biotechnology (2021)
Get full text
Journal Article
Investigation of relationship between EBNA-1 expression level and specific foreign protein productivity in transient gene expression of HEK293 cells
Lee, Joo-Hyoung, Lim, Sung-Min, Park, Sun-Hye, Min, Jeong-Ki, Lee, Gyun Min, Kim, Yeon-Gu
Published in Process biochemistry (1991) (01.04.2017)
Published in Process biochemistry (1991) (01.04.2017)
Get full text
Journal Article
Effect of glucose feeding on the glycosylation quality of antibody produced by a human cell line, F2N78, in fed-batch culture
Seo, Jin Seok, Min, Byung Sup, Kim, Yeon Jung, Cho, Jong Moon, Baek, Eric, Cho, Myung Sam, Lee, Gyun Min
Published in Applied microbiology and biotechnology (01.04.2014)
Published in Applied microbiology and biotechnology (01.04.2014)
Get full text
Journal Article
CHO cells in biotechnology for production of recombinant proteins: current state and further potential
Kim, Jee Yon, Kim, Yeon-Gu, Lee, Gyun Min
Published in Applied microbiology and biotechnology (01.02.2012)
Published in Applied microbiology and biotechnology (01.02.2012)
Get full text
Journal Article
Mitigating Clonal Variation in Recombinant Mammalian Cell Lines
Lee, Jae Seong, Kildegaard, Helene Faustrup, Lewis, Nathan E., Lee, Gyun Min
Published in Trends in biotechnology (Regular ed.) (01.09.2019)
Published in Trends in biotechnology (Regular ed.) (01.09.2019)
Get full text
Journal Article
Electrospun chitosan/poly(vinyl alcohol) reinforced with CaCO3 nanoparticles with enhanced mechanical properties and biocompatibility for cartilage tissue engineering
Sambudi, Nonni Soraya, Sathyamurthy, Madhavi, Lee, Gyun Min, Park, Seung Bin
Published in Composites science and technology (16.01.2015)
Published in Composites science and technology (16.01.2015)
Get full text
Journal Article
Untangling the mechanism of 3‐methyladenine in enhancing the specific productivity: Transcriptome analysis of recombinant Chinese hamster ovary cells treated with 3‐methyladenine
Baek, Eric, Lee, Jae Seong, Lee, Gyun Min
Published in Biotechnology and bioengineering (01.09.2018)
Published in Biotechnology and bioengineering (01.09.2018)
Get full text
Journal Article