Regulation of a Xenobiotic Sulfonation Cascade by Nuclear Pregnane X Receptor (PXR)
Sonoda, Junichiro, Xie, Wen, Rosenfeld, John M., Barwick, Joyce L., Guzelian, Philip S., Evans, Ronald M.
Published in Proceedings of the National Academy of Sciences - PNAS (15.10.2002)
Published in Proceedings of the National Academy of Sciences - PNAS (15.10.2002)
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Humanized xenobiotic response in mice expressing nuclear receptor SXR
Evans, Ronald M, Xie, Wen, Barwick, Joyce L, Downes, Michael, Blumberg, Bruce, Simon, Cynthia M, Nelson, Michael C, Neuschwander-Tetri, Brent A, Brunt, Elizabeth M, Guzelian, Philip S
Published in Nature (London) (27.07.2000)
Published in Nature (London) (27.07.2000)
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Evidence-based toxicology: a comprehensive framework for causation
Guzelian, Philip S, Victoroff, Michael S, Halmes, N Christine, James, Robert C, Guzelian, Christopher P
Published in Human & experimental toxicology (01.04.2005)
Published in Human & experimental toxicology (01.04.2005)
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Reciprocal activation of xenobiotic response genes by nuclear receptors SXR/PXR and CAR
Xie, W, Barwick, J L, Simon, C M, Pierce, A M, Safe, S, Blumberg, B, Guzelian, P S, Evans, R M
Published in Genes & development (01.12.2000)
Published in Genes & development (01.12.2000)
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Identification of Genes Controlled by the Pregnane X Receptor by Microarray Analysis of mRNAs from Pregnenolone 16α-Carbonitrile–Treated Rats
Guzelian, Jeffrey, Barwick, Joyce L., Hunter, Lawrence, Phang, Tzu L., Quattrochi, Linda C., Guzelian, Philip S.
Published in Toxicological sciences (01.12.2006)
Published in Toxicological sciences (01.12.2006)
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Identification of the cytochrome P-450 induced by macrolide antibiotics in rat liver as the glucocorticoid responsive cytochrome P-450p
Wrighton, Steven A, Maurel, Patrick, Schuetz, Erin G, Watkins, Paul B, Young, Beverly, Guzelian, Philip S
Published in Biochemistry (Easton) (01.04.1985)
Published in Biochemistry (Easton) (01.04.1985)
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Isolation and characterization of cloned cDNAs encoding human liver chlordecone reductase
Winters, Charles J, Molowa, David T, Guzelian, Philip S
Published in Biochemistry (Easton) (01.01.1990)
Published in Biochemistry (Easton) (01.01.1990)
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Authority-Based Explanation
Guzelian, Philip S., Guzelian, Christopher P.
Published in Science (American Association for the Advancement of Science) (05.03.2004)
Published in Science (American Association for the Advancement of Science) (05.03.2004)
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Regulation of human liver cytochromes P-450 in family 3A in primary and continuous culture of human hepatocytes
Schuetz, E G, Schuetz, J D, Strom, S C, Thompson, M T, Fisher, R A, Molowa, D T, Li, D, Guzelian, P S
Published in Hepatology (Baltimore, Md.) (01.11.1993)
Published in Hepatology (Baltimore, Md.) (01.11.1993)
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A Novel cis-Acting Element in a Liver Cytochrome P450 3A Gene Confers Synergistic Induction by Glucocorticoids plus Antiglucocorticoids
Quattrochi, Linda C., Mills, A. Scott, Barwick, Joyce L., Yockey, Charles B., Guzelian, Philip S.
Published in The Journal of biological chemistry (01.12.1995)
Published in The Journal of biological chemistry (01.12.1995)
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Comparison of urinary 6-beta-cortisol and the erythromycin breath test as measures of hepatic P450IIIA (CYP3A) activity
Watkins, P B, Turgeon, D K, Saenger, P, Lown, K S, Kolars, J C, Hamilton, T, Fishman, K, Guzelian, P S, Voorhees, J J
Published in Clinical pharmacology and therapeutics (01.09.1992)
Published in Clinical pharmacology and therapeutics (01.09.1992)
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Ectopic expression of MHC class II genes (RT1.B(I) β/α) in rat hepatocytes in vivo and in culture can be elicited by treatment with the pregnane X receptor agonists pregnenolone 16α-carbonitrile and dexamethasone
Jiménez, Braulio D., Maldonado, Lymarie, Dahl, Rolf H., Quattrochi, Linda C., Guzelian, Philip S.
Published in Life sciences (1973) (07.06.2002)
Published in Life sciences (1973) (07.06.2002)
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Induction of cytochrome P-450 and 5-aminolevulinate synthase activities in cultured rat hepatocytes
Sinclair, P R, Bement, W J, Haugen, S A, Sinclair, J F, Guzelian, P S
Published in Cancer research (Chicago, Ill.) (01.09.1990)
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Published in Cancer research (Chicago, Ill.) (01.09.1990)
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Drug metabolism in adult rat hepatocytes in primary monolayer culture
Guzelian, P S, Bissell, D M, Meyer, U A
Published in Gastroenterology (New York, N.Y. 1943) (01.06.1977)
Published in Gastroenterology (New York, N.Y. 1943) (01.06.1977)
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