Hepatic leukemia factor is a novel leukemic stem cell regulator in DNMT3A, NPM1, and FLT3-ITD triple-mutated AML
Garg, Swati, Reyes-Palomares, Armando, He, Lixiazi, Bergeron, Anne, Lavallée, Vincent-Philippe, Lemieux, Sébastien, Gendron, Patrick, Rohde, Christian, Xia, Jianglong, Jagdhane, Prarabdha, Müller-Tidow, Carsten, Lipka, Daniel B., Imren, Suzan, Humphries, R. Keith, Waskow, Claudia, Vick, Binje, Jeremias, Irmela, Richard-Carpentier, Guillaume, Hébert, Josée, Sauvageau, Guy, Zaugg, Judith B., Barabé, Frédéric, Pabst, Caroline
Published in Blood (18.07.2019)
Published in Blood (18.07.2019)
Get full text
Journal Article
anticlastogenic function for the Polycomb Group gene Bmi1
Chagraoui, Jalila, Hébert, Josée, Girard, Simon, Sauvageau, Guy
Published in Proceedings of the National Academy of Sciences - PNAS (29.03.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (29.03.2011)
Get full text
Journal Article
An RNAi Screen Identifies Msi2 and Prox1 as Having Opposite Roles in the Regulation of Hematopoietic Stem Cell Activity
Hope, Kristin J., Cellot, Sonia, Ting, Stephen B., MacRae, Tara, Mayotte, Nadine, Iscove, Norman N., Sauvageau, Guy
Published in Cell stem cell (02.07.2010)
Published in Cell stem cell (02.07.2010)
Get full text
Journal Article
SCL, LMO1 and Notch1 reprogram thymocytes into self-renewing cells
Gerby, Bastien, Tremblay, Cedric S, Tremblay, Mathieu, Rojas-Sutterlin, Shanti, Herblot, Sabine, Hébert, Josée, Sauvageau, Guy, Lemieux, Sébastien, Lécuyer, Eric, Veiga, Diogo F T, Hoang, Trang
Published in PLoS genetics (01.12.2014)
Published in PLoS genetics (01.12.2014)
Get full text
Journal Article
Haploinsufficiency screen highlights two distinct groups of ribosomal protein genes essential for embryonic stem cell fate
Fortier, Simon, MacRae, Tara, Bilodeau, Mélanie, Sargeant, Tobias, Sauvageau, Guy
Published in Proceedings of the National Academy of Sciences - PNAS (17.02.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (17.02.2015)
Get full text
Journal Article
RNA-Seq reveals spliceosome and proteasome genes as most consistent transcripts in human cancer cells
Macrae, Tara, Sargeant, Tobias, Lemieux, Sébastien, Hébert, Josée, Deneault, Eric, Sauvageau, Guy
Published in PloS one (17.09.2013)
Published in PloS one (17.09.2013)
Get full text
Journal Article
RNAi screen identifies Jarid1b as a major regulator of mouse HSC activity
Cellot, Sonia, Hope, Kristin J., Chagraoui, Jalila, Sauvageau, Martin, Deneault, Éric, MacRae, Tara, Mayotte, Nadine, Wilhelm, Brian T., Landry, Josette R., Ting, Stephen B., Krosl, Jana, Humphries, Keith, Thompson, Alexander, Sauvageau, Guy
Published in Blood (29.08.2013)
Published in Blood (29.08.2013)
Get full text
Journal Article
Immunotherapeutic targeting of surfaceome heterogeneity in AML
Bordeleau, Marie-Eve, Audemard, Éric, Métois, Arnaud, Theret, Louis, Lisi, Véronique, Farah, Azer, Spinella, Jean-François, Chagraoui, Jalila, Moujaber, Ossama, Aubert, Léo, Khakipoor, Banafsheh, Mallinger, Laure, Boivin, Isabel, Mayotte, Nadine, Hajmirza, Azadeh, Bonneil, Éric, Béliveau, François, Pfammatter, Sybille, Feghaly, Albert, Boucher, Geneviève, Gendron, Patrick, Thibault, Pierre, Barabé, Frédéric, Lemieux, Sébastien, Richard-Carpentier, Guillaume, Hébert, Josée, Lavallée, Vincent-Philippe, Roux, Philippe P., Sauvageau, Guy
Published in Cell reports (Cambridge) (25.06.2024)
Published in Cell reports (Cambridge) (25.06.2024)
Get full text
Journal Article
CDK7/12/13 inhibition targets an oscillating leukemia stem cell network and synergizes with venetoclax in acute myeloid leukemia
He, Lixiazi, Arnold, Christian, Thoma, Judith, Rohde, Christian, Kholmatov, Maksim, Garg, Swati, Hsiao, Cheng‐Chih, Viol, Linda, Zhang, Kaiqing, Sun, Rui, Schmidt, Christina, Janssen, Maike, MacRae, Tara, Huber, Karin, Thiede, Christian, Hébert, Josée, Sauvageau, Guy, Spratte, Julia, Fluhr, Herbert, Aust, Gabriela, Müller‐Tidow, Carsten, Niehrs, Christof, Pereira, Gislene, Hamann, Jörg, Tanaka, Motomu, Zaugg, Judith B, Pabst, Caroline
Published in EMBO molecular medicine (07.04.2022)
Published in EMBO molecular medicine (07.04.2022)
Get full text
Journal Article
A Functional Screen to Identify Novel Effectors of Hematopoietic Stem Cell Activity
Deneault, Eric, Cellot, Sonia, Faubert, Amélie, Laverdure, Jean-Philippe, Fréchette, Mélanie, Chagraoui, Jalila, Mayotte, Nadine, Sauvageau, Martin, Ting, Stephen B., Sauvageau, Guy
Published in Cell (17.04.2009)
Published in Cell (17.04.2009)
Get full text
Journal Article
Integrin-α3 Is a Functional Marker of Ex Vivo Expanded Human Long-Term Hematopoietic Stem Cells
Tomellini, Elisa, Fares, Iman, Lehnertz, Bernhard, Chagraoui, Jalila, Mayotte, Nadine, MacRae, Tara, Bordeleau, Marie-Ève, Corneau, Sophie, Bisaillon, Richard, Sauvageau, Guy
Published in Cell reports (Cambridge) (23.07.2019)
Published in Cell reports (Cambridge) (23.07.2019)
Get full text
Journal Article
Donor Age and Non-Relapse Mortality: Study of Their Association after HLA-Matched Allogeneic Hematopoietic Cell Transplantation for Acute Myeloid Leukemia and Myelodysplastic Syndrome
Kadri, Yasmine, Phan, Michelle, Bambace, Nadia, Bernard, Léa, Cohen, Sandra, Delisle, Jean-Sébastien, Kiss, Thomas, Lachance, Sylvie, Roy, Denis-Claude, Sauvageau, Guy, Veilleux, Olivier, Roy, Jean, Ahmad, Imran
Published in Current oncology (Toronto) (01.08.2022)
Published in Current oncology (Toronto) (01.08.2022)
Get full text
Journal Article
Overexpression of CD200 is a stem cell-specific mechanism of immune evasion in AML
Herbrich, Shelley, Baran, Natalia, Cai, Tianyu, Weng, Connie, Aitken, Marisa J L, Post, Sean M, Henderson, Jared, Shi, Chunhua, Havranek, Ondrej, Richard-Carpentier, Guillame, Sauvageau, Guy, Baggerly, Keith, Al-Atrash, Gheath, Davis, R Eric, Daver, Naval, Zha, Dongxing, Konopleva, Marina
Published in Journal for immunotherapy of cancer (01.07.2021)
Published in Journal for immunotherapy of cancer (01.07.2021)
Get full text
Journal Article
UBAP2L is a novel BMI1-interacting protein essential for hematopoietic stem cell activity
Bordeleau, Marie-Eve, Aucagne, Romain, Chagraoui, Jalila, Girard, Simon, Mayotte, Nadine, Bonneil, Éric, Thibault, Pierre, Pabst, Caroline, Bergeron, Anne, Barabé, Frédéric, Hébert, Josée, Sauvageau, Martin, Boutonnet, Christel, Meloche, Sylvain, Sauvageau, Guy
Published in Blood (09.10.2014)
Published in Blood (09.10.2014)
Get full text
Journal Article
Scl regulates the quiescence and the long-term competence of hematopoietic stem cells
Lacombe, Julie, Herblot, Sabine, Rojas-Sutterlin, Shanti, Haman, André, Barakat, Stéphane, Iscove, Norman N., Sauvageau, Guy, Hoang, Trang
Published in Blood (28.01.2010)
Published in Blood (28.01.2010)
Get full text
Journal Article