Low Doses of Psilocybin and Ketamine Enhance Motivation and Attention in Poor Performing Rats: Evidence for an Antidepressant Property
Higgins, Guy A, Carroll, Nicole K, Brown, Matt, MacMillan, Cam, Silenieks, Leo B, Thevarkunnel, Sandy, Izhakova, Julia, Magomedova, Lilia, DeLannoy, Ines, Sellers, Edward M
Published in Frontiers in pharmacology (26.02.2021)
Published in Frontiers in pharmacology (26.02.2021)
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Journal Article
The 5-HT2C Receptor Agonist Lorcaserin Reduces Nicotine Self-Administration, Discrimination, and Reinstatement: Relationship to Feeding Behavior and Impulse Control
HIGGINS, Guy A, SILENIEKS, Leo B, ROSSMANN, Anne, RIZOS, Zoe, NOBLE, Kevin, SOKO, Ashlie D, FLETCHER, Paul J
Published in Neuropsychopharmacology (New York, N.Y.) (01.04.2012)
Published in Neuropsychopharmacology (New York, N.Y.) (01.04.2012)
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Journal Article
Pharmacological Modulation of 5-HT2C Receptor Activity Produces Bidirectional Changes in Locomotor Activity, Responding for a Conditioned Reinforcer, and Mesolimbic DA Release in C57BL/6 Mice
Browne, Caleb J, Ji, Xiaodong, Higgins, Guy A, Fletcher, Paul J, Harvey-Lewis, Colin
Published in Neuropsychopharmacology (New York, N.Y.) (01.10.2017)
Published in Neuropsychopharmacology (New York, N.Y.) (01.10.2017)
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Journal Article
Characterization of Amphetamine, Methylphenidate, Nicotine, and Atomoxetine on Measures of Attention, Impulsive Action, and Motivation in the Rat: Implications for Translational Research
Higgins, Guy A, Silenieks, Leo B, MacMillan, Cam, Thevarkunnel, Sandy, Parachikova, Anna I, Mombereau, Cedric, Lindgren, Hanna, Bastlund, Jesper F
Published in Frontiers in pharmacology (24.04.2020)
Published in Frontiers in pharmacology (24.04.2020)
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Journal Article
Profile of Antiemetic Activity of Netupitant Alone or in Combination with Palonosetron and Dexamethasone in Ferrets and Suncus murinus (House Musk Shrew)
Rudd, John A, Ngan, Man P, Lu, Zengbing, Higgins, Guy A, Giuliano, Claudio, Lovati, Emanuela, Pietra, Claudio
Published in Frontiers in pharmacology (31.08.2016)
Published in Frontiers in pharmacology (31.08.2016)
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Journal Article
Lorcaserin: A review of its preclinical and clinical pharmacology and therapeutic potential
Higgins, Guy A., Fletcher, Paul J., Shanahan, William R.
Published in Pharmacology & therapeutics (Oxford) (01.01.2020)
Published in Pharmacology & therapeutics (Oxford) (01.01.2020)
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Journal Article
The antinociceptive and anxiolytic-like effects of the metabotropic glutamate receptor 5 (mGluR5) antagonists, MPEP and MTEP, and the mGluR1 antagonist, LY456236, in rodents: a comparison of efficacy and side-effect profiles
Varty, Geoffrey B, Grilli, Mariagrazia, Forlani, Angelo, Fredduzzi, Silva, Grzelak, Michael E, Guthrie, Donald H, Hodgson, Robert A, Lu, Sherry X, Nicolussi, Elisa, Pond, Annamarie J, Parker, Eric M, Hunter, John C, Higgins, Guy A, Reggiani, Angelo, Bertorelli, Rosalia
Published in Psychopharmacology (01.04.2005)
Published in Psychopharmacology (01.04.2005)
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Journal Article
Pharmacological manipulation of mGlu2 receptors influences cognitive performance in the rodent
Higgins, Guy A., Ballard, Theresa M., Kew, James N.C., Grayson Richards, J., Kemp, John A., Adam, Geo, Woltering, Thomas, Nakanishi, Shigetada, Mutel, Vincent
Published in Neuropharmacology (01.06.2004)
Published in Neuropharmacology (01.06.2004)
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Journal Article
Enhancing effects of nicotine and impairing effects of scopolamine on distinct aspects of performance in computerized attention and working memory tasks in marmoset monkeys
Spinelli, Simona, Ballard, Theresa, Feldon, Joram, Higgins, Guy A., Pryce, Christopher R.
Published in Neuropharmacology (01.08.2006)
Published in Neuropharmacology (01.08.2006)
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Journal Article
Influence of the 5-HT2C receptor antagonist, SB-242084, in tests of anxiety
Martin, James R, Ballard, Theresa M, Higgins, Guy A
Published in Pharmacology, biochemistry and behavior (01.04.2002)
Published in Pharmacology, biochemistry and behavior (01.04.2002)
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Journal Article
Severe Impairment of NMDA Receptor Function in Mice Carrying Targeted Point Mutations in the Glycine Binding Site Results in Drug-Resistant Nonhabituating Hyperactivity
Ballard, Theresa M, Pauly-Evers, Meike, Higgins, Guy A, Ouagazzal, Abdel-Mouttalib, Mutel, Vincent, Borroni, Edilio, Kemp, John A, Bluethmann, Horst, Kew, James N. C
Published in The Journal of neuroscience (01.08.2002)
Published in The Journal of neuroscience (01.08.2002)
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Journal Article
The effect of caffeine to increase reaction time in the rat during a test of attention is mediated through antagonism of adenosine A2A receptors
Higgins, Guy A, Grzelak, Michael E, Pond, Annamarie J, Cohen-Williams, Mary E, Hodgson, Robert A, Varty, Geoffrey B
Published in Behavioural brain research (11.12.2007)
Published in Behavioural brain research (11.12.2007)
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Journal Article
Effect of a single psilocybin treatment on Fos protein expression in male rat brain
Funk, Douglas, Araujo, Joseph, Slassi, Malik, Lanthier, James, Atkinson, Jason, Feng, Daniel, Lau, Winnie, Lê, Anh, Higgins, Guy A.
Published in Neuroscience (16.02.2024)
Published in Neuroscience (16.02.2024)
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Journal Article
Effects of 5-HT2C receptor modulation and the NA reuptake inhibitor atomoxetine in tests of compulsive and impulsive behaviour
Higgins, Guy A., Brown, Matt, St John, Jessica, MacMillan, Cam, Silenieks, Leo B., Thevarkunnel, Sandy
Published in Neuropharmacology (15.06.2020)
Published in Neuropharmacology (15.06.2020)
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Journal Article