Validation of an IFN-gamma ELISpot assay to measure cellular immune responses against viral antigens in non-human primates
Yang, Fan, Patton, Kathryn, Kasprzyk, Theresa, Long, Brian, Gupta, Soumi, Zoog, Stephen J., Tracy, Kristin, Vettermann, Christian
Published in Gene therapy (01.02.2022)
Published in Gene therapy (01.02.2022)
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Journal Article
Loss of Raltegravir Susceptibility by Human Immunodeficiency Virus Type 1 Is Conferred via Multiple Nonoverlapping Genetic Pathways
FRANSEN, Signe, GUPTA, Soumi, DANOVICH, Robert, HAZUDA, Daria, MILLER, Michael, WITMER, Marc, PETROPOULOS, Christos J, WEI HUANG
Published in Journal of Virology (15.11.2009)
Published in Journal of Virology (15.11.2009)
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Journal Article
Pharmacokinetic, pharmacodynamic, and immunogenic rationale for optimal dosing of pegvaliase, a PEGylated bacterial enzyme, in adult patients with phenylketonuria
Qi, Yulan, Patel, Gina, Henshaw, Joshua, Gupta, Soumi, Olbertz, Joy, Larimore, Kevin, Harding, Cary O., Merilainen, Markus, Zori, Roberto, Longo, Nicola, Burton, Barbara K., Li, Mingjin, Gu, Zhonghua, Zoog, Stephen J., Weng, Haoling H., Schweighardt, Becky
Published in Clinical and translational science (01.09.2021)
Published in Clinical and translational science (01.09.2021)
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Journal Article
Combinations of Mutations in the Connection Domain of Human Immunodeficiency Virus Type 1 Reverse Transcriptase: Assessing the Impact on Nucleoside and Nonnucleoside Reverse Transcriptase Inhibitor Resistance
GUPTA, Soumi, FRANSEN, Signe, PAXINOS, Ellen E, STAWISKI, Eric, WEI HUANG, PETROPOULOS, Christos J
Published in Antimicrobial Agents and Chemotherapy (01.05.2010)
Published in Antimicrobial Agents and Chemotherapy (01.05.2010)
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Journal Article
Connection Domain Mutations in HIV-1 Reverse Transcriptase Do Not Impact Etravirine Susceptibility and Virologic Responses to Etravirine-Containing Regimens
GUPTA, Soumi, VINGERHOETS, Johan, PETROPOULOS, Christos J, SCHAPIRO, Jonathan, WEI HUANG, PICCHIO, Gaston, FRANSEN, Signe, TAMBUYZER, Lotke, AZIJN, Hilde, FRANTZELL, Arne, PAREDES, Roger, COAKLEY, Eoin, NIJS, Steven, CLOTET, Bonaventura
Published in Antimicrobial Agents and Chemotherapy (01.06.2011)
Published in Antimicrobial Agents and Chemotherapy (01.06.2011)
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Journal Article
Comparison of Human Immunodeficiency Virus Type 1 Tropism Profiles in Clinical Samples by the Trofile and MT-2 Assays
Coakley, Eoin, Reeves, Jacqueline D, Huang, Wei, Mangas-Ruiz, Marga, Maurer, Irma, Harskamp, Agnes M, Gupta, Soumi, Lie, Yolanda, Petropoulos, Christos J, Schuitemaker, Hanneke, van 't Wout, Angélique B
Published in Antimicrobial Agents and Chemotherapy (01.11.2009)
Published in Antimicrobial Agents and Chemotherapy (01.11.2009)
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Journal Article
The K101P and K103R/V179D Mutations in Human Immunodeficiency Virus Type 1 Reverse Transcriptase Confer Resistance to Nonnucleoside Reverse Transcriptase Inhibitors
PARKIN, Neil T, GUPTA, Soumi, CHAPPEY, Colombe, PETROPOULOS, Christos J
Published in Antimicrobial Agents and Chemotherapy (01.01.2006)
Published in Antimicrobial Agents and Chemotherapy (01.01.2006)
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Journal Article
Characterization of Human Immunodeficiency Virus Gag-Specific Gamma Interferon-Expressing Cells following Protective Mucosal Immunization with Alphavirus Replicon Particles
GUPTA, Soumi, JANANI, Ramesh, POLO, John M, VAJDY, Michael, QIAN BIN, LUCIW, Paul, GREER, Catherine, PERRI, Silvia, LEGG, Harold, DONNELLY, John, BARNETT, Susan, O'HAGAN, Derek
Published in Journal of Virology (01.06.2005)
Published in Journal of Virology (01.06.2005)
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Journal Article
Vaccination of Cats with Attenuated Feline Immunodeficiency Virus Proviral DNA Vaccine Expressing Gamma Interferon
GUPTA, Soumi, LEUTENEGGER, Christian M, DEAN, Gregg A, STECKBECK, Jonathan D, COLE, Kelly Stefano, SPARGER, Ellen E
Published in Journal of Virology (01.01.2007)
Published in Journal of Virology (01.01.2007)
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Journal Article
Pegvaliase for the treatment of phenylketonuria: Results of a long-term phase 3 clinical trial program (PRISM)
Thomas, Janet, Levy, Harvey, Amato, Stephen, Vockley, Jerry, Zori, Roberto, Dimmock, David, Harding, Cary O., Bilder, Deborah A., Weng, Haoling H., Olbertz, Joy, Merilainen, Markus, Jiang, Joy, Larimore, Kevin, Gupta, Soumi, Gu, Zhonghua, Northrup, Hope
Published in Molecular genetics and metabolism (01.05.2018)
Published in Molecular genetics and metabolism (01.05.2018)
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Journal Article
Achieving efficacy in subjects with sustained pegvaliase-neutralizing antibody responses
Aryal, Madhukar, Lau, Kelly, Boyer, Ryan, Zhou, Huiyu, Abend, Johanna, Gu, Karen, Olbertz, Joy, Gupta, Soumi, Zoog, Stephen, Larimore, Kevin
Published in Molecular genetics and metabolism (01.11.2021)
Published in Molecular genetics and metabolism (01.11.2021)
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Journal Article
Interim 52-week analysis of immunogenicity to the vector capsid and transgene-expressed human FVIII in GENEr8-1, a phase 3 clinical study of valoctocogene roxaparvovec, an AAV5-mediated gene therapy for hemophilia A
Long, Brian, Fong, Sylvia, Handyside, Britta, Robinson, Tara, Day, Jonathan, Yu, Hua, Lau, Kelly, Patton, Kathryn, de Hart, Greg, Henshaw, Josh, Agarwal, Suresh, Vettermann, Christian, Gupta, Soumi
Published in Journal of hepatology (01.07.2022)
Published in Journal of hepatology (01.07.2022)
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Journal Article
Clinical immunogenicity outcomes from GENEr8-1, a phase 3 study of valoctocogene roxaparvovec, an AAV5-vectored gene therapy for hemophilia A
Long, Brian R., Robinson, Tara M., Day, Jonathan R.S., Yu, Hua, Lau, Kelly, Imtiaz, Urooj, Patton, Kathryn S., de Hart, Greg, Henshaw, Joshua, Agarwal, Suresh, Vettermann, Christian, Zoog, Stephen J., Gupta, Soumi
Published in Molecular therapy (03.07.2024)
Published in Molecular therapy (03.07.2024)
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Journal Article
Depletion of interfering IgG and IgM is critical to determine the role of IgE in pegvaliase-associated hypersensitivity
Larimore, Kevin, Nguyen, Thom, Badillo, Benjamin, Lau, Kelly, Zori, Roberto, Shepherd, Gillian, Zoog, Stephen J., Weng, Haoling H., Gupta, Soumi
Published in Journal of immunological methods (01.05.2019)
Published in Journal of immunological methods (01.05.2019)
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Journal Article
Association of immune response with efficacy and safety outcomes in adults with phenylketonuria administered pegvaliase in phase 3 clinical trials
Gupta, Soumi, Lau, Kelly, Harding, Cary O., Shepherd, Gillian, Boyer, Ryan, Atkinson, John P., Knight, Vijaya, Olbertz, Joy, Larimore, Kevin, Gu, Zhonghu, Li, Mingjin, Rosen, Orli, Zoog, Stephen J., Weng, Haoling H., Schweighardt, Becky
Published in EBioMedicine (01.11.2018)
Published in EBioMedicine (01.11.2018)
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Journal Article
Trends in darunavir resistance-associated mutations and phenotypic resistance in commercially tested United States clinical samples between 2006 and 2012
Lathouwers, Erkki, Gupta, Soumi, Haddad, Mojgan, Paquet, Agnes, de Meyer, Sandra, Baugh, Bryan
Published in AIDS research and human retroviruses (01.06.2015)
Published in AIDS research and human retroviruses (01.06.2015)
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Journal Article
2021 White Paper on Recent Issues in Bioanalysis: TAb/NAb, Viral Vector CDx, Shedding Assays; CRISPR/Cas9 & CAR-T Immunogenicity; PCR & Vaccine Assay Performance; ADA Assay Comparability & Cut Point Appropriateness
Loo, Lina, Harris, Shannon, Milton, Mark, Meena, Lembke, Wibke, Berisha, Flora, Bertholet, Sylvie, Dessy, Francis, Dodge, Robert, Fang, Xiaodong, Fiscella, Michele, Garofolo, Fabio, Gorovits, Boris, Gupta, Soumi, Jawa, Vibha, Ishii-Watabe, Akiko, Long, Brian, Lu, Yanmei, Mack, Timothy, McGuire, Kristina, Nolan, Katrina, Pan, Luying, Potthoff, Bernd, Purushothama, Shobha, Smith, Dean, Solstad, Therese, Sonderegger, Ivo, Taddeo, Frank, Tangri, Shabnam, Wagner, Leslie, Wu, Bonnie, Xu, Yuanxin, Kirshner, Susan, Verthelyi, Daniela, Yan, Haoheng, Maxfield, Kimberly, Pedras-Vasconcelos, Joao, Abhari, Mohsen Rajabi, Gupta, Swati, Wu, Yuling, Rajadhyaksha, Manoj, Andisik, Matthew, Baltrukonis, Daniel, Cherry, Elana, Cludts, Isabelle, Gunn, George, Millner, Anders Holm, Jordan, Gregor, Kar, Sumit, Kubiak, Robert, Lotz, Gregor P, Palmer, Rachel, Peng, Kun, Poetzl, Johann, Richards, Susan, Savoie, Natasha, Staack, Roland F, Stubenrauch, Kay, Wadhwa, Meenu, Waxenecker, Günter, Yang, Tong-Yuan, Zhang, Lucia
Published in Bioanalysis (01.06.2022)
Published in Bioanalysis (01.06.2022)
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Journal Article
2022 White Paper on Recent Issues in Bioanalysis: FDA Draft Guidance on Immunogenicity Information in Prescription Drug Labeling, LNP & Viral Vectors Therapeutics/Vaccines Immunogenicity, Prolongation Effect, ADA Affinity, Risk-based Approaches, NGS, qPCR, ddPCR Assays
Pan, Luying, Mora, Johanna, Walravens, Karl, Wagner, Leslie, Hopper, Shirley, Loo, Lina, Bettoun, David, Bond, Sarah, Dessy, Francis, Downing, Sean, Garofolo, Fabio, Gupta, Soumi, Henderson, Neil, Irwin, Chad, Ishii-Watabe, Akiko, Kar, Sumit, Jawa, Vibha, Joseph, Julie, Malvaux, Ludovic, Marshall, Jean-Claude, McDevitt, Jessica, Mohapatra, Susovan, Seitzer, Jessica, Smith, Justin, Solstad, Therese, Sugimoto, Hiroshi, Tounekti, Omar, Wu, Bonnie, Wu, Yuling, Xu, Yuanxin, Xu, Joshua, Yamamoto, Takenori, Yang, Lin, Torri, Albert, Kirshner, Susan, Maxfield, Kimberly, Vasconcelos, Joao Pedras, Abhari, Mohsen Rajabi, Verthelyi, Daniela, Brodsky, Eric, Carrasco-Triguero, Montserrat, Kamerud, John, Andisik, Matthew, Baltrukonis, Daniel, Bivi, Nicoletta, Cludts, Isabelle, Coble, Kelly, Gorovits, Boris, Gunn, George R, Gupta, Swati, Millner, Anders Holm, Joyce, Alison, Kubiak, Robert J, Kumar, Seema, Liao, Karen, Manangeeswaran, Mohanraj, Partridge, Michael, Pine, Samuel, Poetzl, Johann, Rajadhyaksha, Manoj, Rasamoelisolo, Michele, Richards, Susan, Song, Yuan, Swanson, Steven, Thacker, Seth, Wadhwa, Meenu, Wolf, Andreas, Zhang, Lucia, Zhou, Lin
Published in Bioanalysis (01.07.2023)
Published in Bioanalysis (01.07.2023)
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Journal Article
Evolution of integrase resistance during failure of integrase inhibitor-based antiretroviral therapy
Hatano, Hiroyu, Lampiris, Harry, Fransen, Signe, Gupta, Soumi, Huang, Wei, Hoh, Rebecca, Martin, Jeffrey N, Lalezari, Jacob, Bangsberg, David, Petropoulos, Christos, Deeks, Steven G
Published in Journal of acquired immune deficiency syndromes (1999) (01.08.2010)
Published in Journal of acquired immune deficiency syndromes (1999) (01.08.2010)
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