Inhibition of Bruton's TK regulates macrophage NF‐κB and NLRP3 inflammasome activation in metabolic inflammation
Purvis, Gareth S.D., Collino, Massimo, Aranda‐Tavio, Haidee, Chiazza, Fausto, O'Riordan, Caroline E., Zeboudj, Lynda, Mohammad, Shireen, Collotta, Debora, Verta, Roberta, Guisot, Nicolas E.S., Bunyard, Peter, Yaqoob, Magdi M., Greaves, David R., Thiemermann, Christoph
Published in British journal of pharmacology (01.10.2020)
Published in British journal of pharmacology (01.10.2020)
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Journal Article
Reaction of Glyconitriles with Organometallic Reagents: Access to Acyl β‑C‑Glycosides
Guisot, Nicolas E. S, Ella Obame, Idriss, Ireddy, Prathap, Nourry, Arnaud, Saluzzo, Christine, Dujardin, Gilles, Dubreuil, Didier, Pipelier, Muriel, Guillarme, Stéphane
Published in Journal of organic chemistry (18.03.2016)
Published in Journal of organic chemistry (18.03.2016)
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Journal Article
Addition of Organozinc Reagents to Glycopyranosyl Cyanides: Access to Keto Ester‐C‐glycosides or Unsaturated Acyl‐C‐glycosides
Ella Obame, Idriss, Ireddy, Prathap, Guisot, Nicolas E. S., Nourry, Arnaud, Saluzzo, Christine, Dujardin, Gilles, Dubreuil, Didier, Pipelier, Muriel, Guillarme, Stéphane
Published in European journal of organic chemistry (17.04.2018)
Published in European journal of organic chemistry (17.04.2018)
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Journal Article
Rho-associated protein kinase 1 inhibition in hepatocytes attenuates nonalcoholic steatohepatitis
Dohnalkova, Ester, Bayer, Rachel L, Guo, Qianqian, Bamidele, Adebowale O, Kim Lee, Hyun Se, Valenzuela-Pérez, Lucía, Krishnan, Anuradha, Pavelko, Kevin D, Guisot, Nicolas E S, Bunyard, Peter, Kim, Young-Bum, Ibrahim, Samar H, Gores, Gregory J, Hirsova, Petra
Published in Hepatology communications (01.06.2023)
Published in Hepatology communications (01.06.2023)
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Journal Article
REDX08608, a Novel, Potent and Selective, Reversible BTK Inhibitor with Efficacy and Equivalent Potency Against Wild-Type and Mutant C481S BTK
Guisot, Nicolas E.S., Best, Stuart A., Wright, Victoria, Thomason, Andrew, Woyach, Jennifer A., Mantel, Rose, McClanahan, Fabienne, Abet, Valentina, Castagna, Diana, Cousin, Peggy, Emmerich, Juliette, Ho, Kelvin, Kelly, James Russell, King-Tours, James, Lyons, Kristina, Muller, Melanie, Refuerzo, Julienne, Sargent, Louise, Talab, Fatima, Bingham, Matilda, Phillips, Caroline, Armer, Richard
Published in Blood (02.12.2016)
Published in Blood (02.12.2016)
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Journal Article
A straightforward route to spiroketals
Ardes-Guisot, Nicolas, Ouled-Lahoucine, Bani, Canet, Isabelle, Sinibaldi, Marie-Eve
Published in Tetrahedron letters (26.11.2007)
Published in Tetrahedron letters (26.11.2007)
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Journal Article
Selection of the biological activity of DNJ neoglycoconjugates through click length variation of the side chain
Ardes-Guisot, Nicolas, Alonzi, Dominic S., Reinkensmeier, Gabriele, Butters, Terry D., Norez, Caroline, Becq, Frederic, Shimada, Yousuke, Nakagawa, Shinpei, Kato, Atsushi, Bleriot, Yves, Sollogoub, Matthieu, Vauzeilles, Boris
Published in Organic & biomolecular chemistry (07.08.2011)
Published in Organic & biomolecular chemistry (07.08.2011)
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Journal Article
Hybrid Bioorganic-Inorganic Materials Prepared by Site-Specific Ligation of Peptides to Functionalized Polydisperse Silica Particles
Joly, Pascal, Ardès-Guisot, Nicolas, Kar, Samiran, Granier, Michel, Durand, Jean-Olivier, Melnyk, Oleg
Published in European Journal of Organic Chemistry (01.06.2005)
Published in European Journal of Organic Chemistry (01.06.2005)
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Book Review
Journal Article
Trichlorosilane Isocyanate as Coupling Agent for Mild Conditions Functionalization of Silica-Coated Surfaces
Ardès-Guisot, Nicolas, Durand, Jean-Olivier, Granier, Michel, Perzyna, Aurore, Coffinier, Yannick, Grandidier, Bruno, Wallart, Xavier, Stievenard, Didier
Published in Langmuir (11.10.2005)
Published in Langmuir (11.10.2005)
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Journal Article
Development of Novel Selective DDR1 Inhibitors with the Potential to Treat CKD: SA-OR90
Guisot, Nicolas E., Wilcock, Daniel J., Bhamra, Inder, Eckersley, Kay, Douglas, Gayle E., Ho, Kelvin, Jones, Cliff, Leng, Daniel J., Lloyd-Weston, Jack W., Marshall, Amy B., Mckeever, Helen, Phillips, Caroline, Preece, Shân, Ryan, James, Street, Robert J., Armer, Richard
Published in Journal of the American Society of Nephrology (01.11.2023)
Published in Journal of the American Society of Nephrology (01.11.2023)
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Journal Article
암 및 섬유성 질환의 치료를 위한 DDR1 및 DDR2 억제제
JONES CLIFFORD D, BHAMRA INDER, VARELA RODRIGUEZ ANA, GUISOT NICOLAS E.S
Year of Publication 24.06.2024
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Year of Publication 24.06.2024
Patent
Abstract 720: Combining zelasudil, a small molecule ROCK2 inhibitor, with chemotherapy or immunotherapy improves response in preclinical models of pancreatic cancer
Pajic, Marina, McLean, Benjamin, Fajardo, Diego Chacon, Porazinski, Sean, Upton, Dannielle H., Schuhmacher, Diana, Istadi, Aji, Cox, Thomas, Timpson, Paul, Wilcock, Daniel J., Anderson, Katie J., Mason, Helen, Guisot, Nicolas E., Jones, Clifford D., Phillips, Caroline, Armer, Richard
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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Journal Article
S-5--3-4-5--2--1-111--2--1H--4- - SPRAY-DRIED DISPERSIONS AND FORMULATIONS OF S-5-AMINO-3-4-5-FLUORO-2-METHOXYBENZAMIDOMETHYLPHENYL-1-111-TRIFLUORO PROPAN-2-YL-lH-PYRAZOLE-4-CARBOXAMIDE
BRANDHUBER BARBARA J, EARY CHARLES TODD, SPENCER STACEY RENEE, KHAN FIRAS, GUISOT NICOLAS, KENNA ANDREW, RENSHAW VIVIAN F. H, BRENT LAUREN T
Year of Publication 19.12.2023
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Year of Publication 19.12.2023
Patent
S-5--3-4-5--2--1-111--2--1H--4- - SPRAY-DRIED DISPERSIONS AND FORMULATIONS OF S-5-AMINO-3-4-5-FLUORO-2-METHOXYBENZAMIDOMETHYLPHENYL-1-111-TRIFLUORO PROPAN-2-YL-lH-PYRAZOLE-4-CARBOXAMIDE
BRANDHUBER BARBARA J, EARY CHARLES TODD, SPENCER STACEY RENEE, KHAN FIRAS, GUISOT NICOLAS, KENNA ANDREW, RENSHAW VIVIAN F. H, BRENT LAUREN T
Year of Publication 27.06.2023
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Year of Publication 27.06.2023
Patent