The Molecular Tweezer CLR01 Stabilizes a Disordered Protein–Protein Interface
Bier, David, Mittal, Sumit, Bravo-Rodriguez, Kenny, Sowislok, Andrea, Guillory, Xavier, Briels, Jeroen, Heid, Christian, Bartel, Maria, Wettig, Burkhard, Brunsveld, Luc, Sanchez-Garcia, Elsa, Schrader, Thomas, Ottmann, Christian
Published in Journal of the American Chemical Society (15.11.2017)
Published in Journal of the American Chemical Society (15.11.2017)
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Journal Article
Different binding modalities of quercetin to inositol-requiring enzyme 1 of S. cerevisiae and human lead to opposite regulation
Mahdizadeh, S. Jalil, Grandén, Johan, Pelizzari-Raymundo, Diana, Guillory, Xavier, Carlesso, Antonio, Chevet, Eric, Eriksson, Leif A.
Published in Communications chemistry (05.01.2024)
Published in Communications chemistry (05.01.2024)
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Journal Article
A novel IRE1 kinase inhibitor for adjuvant glioblastoma treatment
Pelizzari-Raymundo, Diana, Doultsinos, Dimitrios, Pineau, Raphael, Sauzay, Chloé, Koutsandreas, Thodoris, Langlais, Timothy, Carlesso, Antonio, Gkotsi, Elena, Negroni, Luc, Avril, Tony, Chatziioannou, Aristotelis, Chevet, Eric, Eriksson, Leif A., Guillory, Xavier
Published in iScience (19.05.2023)
Published in iScience (19.05.2023)
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Journal Article
Coalescent simulations indicate that the São Francisco River is a biogeographic barrier for six vertebrates in a seasonally dry South American forest
Coelho, Felipe Eduardo Alves, Guillory, Wilson Xavier, Gehara, Marcelo
Published in Frontiers in ecology and evolution (23.09.2022)
Published in Frontiers in ecology and evolution (23.09.2022)
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Journal Article
Stereoselective Synthesis of a Bicyclic Norsesquiterpene Backbone - A Possible Route to Nardosinane Derivatives
Selaïmia-Ferdjani, Ouassila, Kar, Anirban, Chavan, Sambhaji P., Horeau, Maxime, Viault, Guillaume, Pouessel, Jacky, Guillory, Xavier, Blot, Virginie, Tessier, Arnaud, Planchat, Aurelien, Jacquemin, Denis, Dubreuil, Didier, Pipelier, Muriel
Published in European journal of organic chemistry (01.11.2013)
Published in European journal of organic chemistry (01.11.2013)
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Journal Article
Discovery of 14‐3‐3 PPI Stabilizers by Extension of an Amidine‐Substituted Thiophene Fragment
Wu, Qi, Centorrino, Federica, Guillory, Xavier, Wolter, Madita, Ottmann, Christian, Cossar, Peter J., Brunsveld, Luc
Published in Chembiochem : a European journal of chemical biology (02.01.2024)
Published in Chembiochem : a European journal of chemical biology (02.01.2024)
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Journal Article
Supramolecular Enhancement of a Natural 14–3–3 Protein Ligand
Guillory, Xavier, Hadrović, Inesa, de Vink, Pim J, Sowislok, Andrea, Brunsveld, Luc, Schrader, Thomas, Ottmann, Christian
Published in Journal of the American Chemical Society (01.09.2021)
Published in Journal of the American Chemical Society (01.09.2021)
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Journal Article
Pharmacological Targeting of IRE1 in Cancer
Raymundo, Diana Pelizzari, Doultsinos, Dimitrios, Guillory, Xavier, Carlesso, Antonio, Eriksson, Leif A, Chevet, Eric
Published in Trends in cancer (01.12.2020)
Published in Trends in cancer (01.12.2020)
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Journal Article
Structure simplification of the Securinine skeleton reveals the importance of BCD ring system for the cytotoxic activity on HCT116 and HL60 cell lines
Le Roch, Myriam, Afonso, Damien, Chirkin, Egor, Guillory, Xavier, Porée, François-Hugues
Published in Bioorganic & medicinal chemistry (15.03.2022)
Published in Bioorganic & medicinal chemistry (15.03.2022)
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Journal Article
From Tethered to Freestanding Stabilizers of 14‐3‐3 Protein‐Protein Interactions through Fragment Linking
Visser, Emira J., Jaishankar, Priyadarshini, Sijbesma, Eline, Pennings, Marloes A. M., Vandenboorn, Edmee M. F., Guillory, Xavier, Neitz, R. Jeffrey, Morrow, John, Dutta, Shubhankar, Renslo, Adam R., Brunsveld, Luc, Arkin, Michelle R., Ottmann, Christian
Published in Angewandte Chemie International Edition (11.09.2023)
Published in Angewandte Chemie International Edition (11.09.2023)
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Journal Article
Fragment-based Differential Targeting of PPI Stabilizer Interfaces
Guillory, Xavier, Wolter, Madita, Leysen, Seppe, Neves, João Filipe, Kuusk, Ave, Genet, Sylvia, Somsen, Bente, Morrow, John Kenneth, Rivers, Emma, van Beek, Lotte, Patel, Joe, Goodnow, Robert, Schoenherr, Heike, Fuller, Nathan, Cao, Qing, Doveston, Richard G, Brunsveld, Luc, Arkin, Michelle R, Castaldi, Paola, Boyd, Helen, Landrieu, Isabelle, Chen, Hongming, Ottmann, Christian
Published in Journal of medicinal chemistry (09.07.2020)
Published in Journal of medicinal chemistry (09.07.2020)
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Journal Article
Mono‐ and Bivalent 14‐3‐3 Inhibitors for Characterizing Supramolecular “Lysine Wrapping” of Oligoethylene Glycol (OEG) Moieties in Proteins
Yilmaz, Elvan, Bier, David, Guillory, Xavier, Briels, Jeroen, Ruiz‐Blanco, Yasser B., Sanchez‐Garcia, Elsa, Ottmann, Christian, Kaiser, Markus
Published in Chemistry : a European journal (18.09.2018)
Published in Chemistry : a European journal (18.09.2018)
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Journal Article
From Tethered to Freestanding Stabilizers of 14‐3‐3 Protein‐Protein Interactions through Fragment Linking
Visser, Emira J., Jaishankar, Priyadarshini, Sijbesma, Eline, Pennings, Marloes A. M., Vandenboorn, Edmee M. F., Guillory, Xavier, Neitz, R. Jeffrey, Morrow, John, Dutta, Shubhankar, Renslo, Adam R., Brunsveld, Luc, Arkin, Michelle R., Ottmann, Christian
Published in Angewandte Chemie (11.09.2023)
Published in Angewandte Chemie (11.09.2023)
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Journal Article
Gene Editing Corrects In Vitro a G > A GLB1 Transition from a GM1 Gangliosidosis Patient
Leclerc, Delphine, Goujon, Louise, Jaillard, Sylvie, Nouyou, Bénédicte, Cluzeau, Laurence, Damaj, Léna, Dubourg, Christèle, Etcheverry, Amandine, Levade, Thierry, Froissart, Roseline, Dréano, Stéphane, Guillory, Xavier, Eriksson, Leif A, Launay, Erika, Mouriaux, Frédéric, Belaud-Rotureau, Marc-Antoine, Odent, Sylvie, Gilot, David
Published in CRISPR journal (01.02.2023)
Published in CRISPR journal (01.02.2023)
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Journal Article
COMPOUNDS CONTAINING A HYDROXYPHENYL MOIETY AND THEIR USE
PELIZZARI-RAYMUNDO, Diana, DOULTSINOS, Dimitrios, ERIKSSON, Leif A, LANGLAIS, Timothy, SUERON, Sébastien, GOUAULT, Nicolas, GUILLORY, Xavier, CHEVET, Eric, CARREAUX, François, CARLESSO, Antonio, PORÉE, François-Hugues
Year of Publication 13.07.2023
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Year of Publication 13.07.2023
Patent
Gene editing is suitable to treat GM1 Gangliosidosis: a proof-of-concept study
Leclerc, Delphine, Goujon, Louise, Jaillard, Sylvie, Nouyou, Benedicte, Cluzeau, Laurence, Damaj, Lena, Dubourg, Christele, Etcheverry, Amandine, Levade, Thierry, Froissart, Roseline, Dreano, Stephane, Guillory, Xavier, Eriksson, Leif A, Launay, Erika, Mouriaux, Frederic, Marc-Antoine Belaud-Rotureau, Odent, Sylvie, Gilot, David
Published in bioRxiv (17.04.2022)
Published in bioRxiv (17.04.2022)
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