Search Results - "GUILFORD WILLIAM J" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

A β-Oxidation-Resistant Lipoxin A4 Analog Treats Hapten-Induced Colitis by Attenuating Inflammation and Immune Dysfunction

A β-Oxidation-Resistant Lipoxin A4 Analog Treats Hapten-Induced Colitis by Attenuating Inflammation and Immune Dysfunction

by Fiorucci, Stefano, Wallace, John L., Mencarelli, Andrea, Distrutti, Eleonora, Rizzo, Giovanni, Farneti, Silvana, Morelli, Antonio, Tseng, Jih-Lie, Suramanyam, Babu, Guilford, William J., Parkinson, John F., Ignarro, Louis J.
Published in Proceedings of the National Academy of Sciences - PNAS (02.11.2004)

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Journal Article

Lipoxin A4 Analogs Attenuate Induction of Intestinal Epithelial Proinflammatory Gene Expression and Reduce the Severity of Dextran Sodium Sulfate-Induced Colitis

Lipoxin A4 Analogs Attenuate Induction of Intestinal Epithelial Proinflammatory Gene Expression and Reduce the Severity of Dextran Sodium Sulfate-Induced Colitis

by Gewirtz, Andrew T, Collier-Hyams, Lauren S, Young, Andrew N, Kucharzik, Torsten, Guilford, William J, Parkinson, John F, Williams, Ifor R, Neish, Andrew S, Madara, James L
Published in The Journal of immunology (1950) (15.05.2002)

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Journal Article

Lipoxins and novel 15‐epi‐lipoxin analogs display potent anti‐inflammatory actions after oral administration

Lipoxins and novel 15‐epi‐lipoxin analogs display potent anti‐inflammatory actions after oral administration

by Bannenberg, Gerard, Moussignac, Rose‐Laure, Gronert, Karsten, Devchand, Pallavi R, Schmidt, Birgitta A, Guilford, William J, Bauman, John G, Subramanyam, Babu, Daniel Perez, H, Parkinson, John F, Serhan, Charles N
Published in British journal of pharmacology (01.09.2004)

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Journal Article

Second-generation beta-oxidation resistant 3-oxa-lipoxin A4 analogs

Second-generation beta-oxidation resistant 3-oxa-lipoxin A4 analogs

by Guilford, William J, Parkinson, John F
Published in Prostaglandins, leukotrienes and essential fatty acids (01.09.2005)

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Journal Article

Lipoxin A₄ stable analogs reduce allergic airway responses via mechanisms distinct from CysLT1 receptor antagonism

Lipoxin A₄ stable analogs reduce allergic airway responses via mechanisms distinct from CysLT1 receptor antagonism

by Levy, Bruce D, Lukacs, Nicholas W, Berlin, Aaron A, Schmidt, Birgitta, Guilford, William J, Serhan, Charles N, Parkinson, John F
Published in The FASEB journal (01.12.2007)

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Design, Synthesis, and Activity of a Novel Series of Factor Xa Inhibitors: Optimization of Arylamidine Groups

Design, Synthesis, and Activity of a Novel Series of Factor Xa Inhibitors: Optimization of Arylamidine Groups

by Phillips, Gary, Guilford, William J, Buckman, Brad O, Davey, David D, Eagen, Keith A, Koovakkat, Sunil, Liang, Amy, McCarrick, Meg, Mohan, Raju, Ng, Howard P, Pinkerton, Michael, Subramanyam, Babu, Ho, Elena, Trinh, Lan, Whitlow, Marc, Wu, Shung, Xu, Wei, Morrissey, Michael M
Published in Journal of medicinal chemistry (06.06.2002)

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Novel 3-Oxa Lipoxin A4 Analogues with Enhanced Chemical and Metabolic Stability Have Anti-inflammatory Activity in Vivo

Novel 3-Oxa Lipoxin A4 Analogues with Enhanced Chemical and Metabolic Stability Have Anti-inflammatory Activity in Vivo

by Guilford, William J, Bauman, John G, Skuballa, Werner, Bauer, Shawn, Wei, Guo Ping, Davey, David, Schaefer, Caralee, Mallari, Cornell, Terkelsen, Jennifer, Tseng, Jih-Lie, Shen, Jun, Subramanyam, Babu, Schottelius, Arndt J, Parkinson, John F
Published in Journal of medicinal chemistry (08.04.2004)

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Synthesis of glutamic acid analogs as potent inhibitors of leukotriene A4 hydrolase

Synthesis of glutamic acid analogs as potent inhibitors of leukotriene A4 hydrolase

by KIRKLAND, Thomas A, ADLER, Marc, THUNNISSEN, Marjolein, TRINH, Lan, WHITLOW, Marc, BIN YE, HONG YE, PARKINSON, John, GUILFORD, William J, BAUMAN, John G, MING CHEN, HAEGGSTRÖM, Jesper Z, KING, Beverly, KOCHANNY, Monica J, LIANG, Amy M, MENDOZA, Lisa, PHILLIPS, Gary B
Published in Bioorganic & medicinal chemistry (01.05.2008)

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Synthesis of N-alkyl glycine amides as potent inhibitors of leukotriene A4 hydrolase

Synthesis of N-alkyl glycine amides as potent inhibitors of leukotriene A4 hydrolase

by BIN YE, BAUMAN, John, MAY, Karen, MENDOZA, Lisa, PHILLIPS, Gary, SELCHAU, Victor, SCHLYER, Sabine, TSENG, Jih-Lie, WEI, Robert G, HONG YE, PARKINSON, John, GUILFORD, William J, MING CHEN, DAVEY, David, KHIM, Seock-Kyu, KING, Beverly, KIRKLAND, Thomas, KOCHANNY, Monica, LIANG, Amy, LENTZ, Dao
Published in Bioorganic & medicinal chemistry letters (15.07.2008)

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Discovery of novel and potent aryl diamines as leukotriene A4 hydrolase inhibitors

Discovery of novel and potent aryl diamines as leukotriene A4 hydrolase inhibitors

by KHIM, Seock-Kyu, BAUMAN, John, PHILLIPS, Gary, TSENG, Jih-Lie, WEI, Robert G, HONG YE, LIMEI YU, PARKINSON, John, GUILFORD, William J, EVANS, Jarred, FREEMAN, Beverly, KING, Beverly, KIRKLAND, Thomas, KOCHANNY, Monica, LENTZ, Dao, LIANG, Amy, MENDOZA, Lisa
Published in Bioorganic & medicinal chemistry letters (15.07.2008)

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Journal Article

The mechanism of the chorismate mutase reaction

The mechanism of the chorismate mutase reaction

by Guilford, William J, Copley, Shelley D, Knowles, Jeremy R
Published in Journal of the American Chemical Society (01.08.1987)

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Journal Article

BERAPROST ISOMER AS AGENT FOR THE TREATMENT OF VIRAL INFECTION

BERAPROST ISOMER AS AGENT FOR THE TREATMENT OF VIRAL INFECTION

by FAULDS DARYL H, GUILFORD WILLIAM J
Year of Publication 25.11.2015

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Patent

EP2 AND EP4 AGONISTS AS AGENTS FOR TREATMENT OF INFLUENZA A VIRAL INFECTION

EP2 AND EP4 AGONISTS AS AGENTS FOR TREATMENT OF INFLUENZA A VIRAL INFECTION

by SEIFERT WOLFGANG, FAULDS DARYL, GUILFORD WILLIAM J
Year of Publication 02.04.2015

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Patent

COMBINATION THERAPY TREATMENT FOR VIRAL INFECTIONS

COMBINATION THERAPY TREATMENT FOR VIRAL INFECTIONS

by FAULDS DARYL H, GUILFORD WILLIAM J
Year of Publication 23.08.2012

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Patent

Discovery of N-[2-[5-[Amino(imino)methyl]-2-hydroxyphenoxy]-3,5-difluoro- 6-[3-(4,5-dihydro-1-methyl-1H-imidazol-2-yl)phenoxy]pyridin-4-yl]-N-methylglycine (ZK-807834): A Potent, Selective, and Orally Active Inhibitor of the Blood Coagulation Enzyme Factor Xa

Discovery of N-[2-[5-[Amino(imino)methyl]-2-hydroxyphenoxy]-3,5-difluoro- 6-[3-(4,5-dihydro-1-methyl-1H-imidazol-2-yl)phenoxy]pyridin-4-yl]-N-methylglycine (ZK-807834): A Potent, Selective, and Orally Active Inhibitor of the Blood Coagulation Enzyme Factor Xa

by Phillips, Gary B, Buckman, Brad O, Davey, David D, Eagen, Keith A, Guilford, William J, Hinchman, Josephine, Ho, Elena, Koovakkat, Sunil, Liang, Amy, Light, David R, Mohan, Raju, Ng, Howard P, Post, Joseph M, Shaw, Kenneth J, Smith, Dave, Subramanyam, Babu, Sullivan, Mark E, Trinh, Lan, Vergona, Ron, Walters, Janette, White, Kathy, Whitlow, Marc, Wu, Shung, Xu, Wei, Morrissey, Michael M
Published in Journal of medicinal chemistry (10.09.1998)

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Journal Article

Conformation of a Bound Inhibitor of Blood Coagulant Factor Xa

Conformation of a Bound Inhibitor of Blood Coagulant Factor Xa

by Studelska, Daniel R, McDowell, Lynda M, Adler, Marc, O'Connor, Robert D, Mehta, Anil K, Guilford, William J, Dallas, Jerry L, Arnaiz, Damian, Light, David R, Schaefer, Jacob
Published in Biochemistry (Easton) (08.07.2003)

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Journal Article

Synthesis, Characterization, and Structure−Activity Relationships of Amidine-Substituted (Bis)benzylidene-Cycloketone Olefin Isomers as Potent and Selective Factor Xa Inhibitors

Synthesis, Characterization, and Structure−Activity Relationships of Amidine-Substituted (Bis)benzylidene-Cycloketone Olefin Isomers as Potent and Selective Factor Xa Inhibitors

by Guilford, William J, Shaw, Kenneth J, Dallas, Jerry L, Koovakkat, Sunil, Lee, Wheeseong, Liang, Amy, Light, David R, McCarrick, Margaret A, Whitlow, Marc, Ye, Bin, Morrissey, Michael M
Published in Journal of medicinal chemistry (30.12.1999)

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Journal Article

Development of a homogeneous time-resolved fluorescence leukotriene B4 assay for determining the activity of leukotriene A4 hydrolase

Development of a homogeneous time-resolved fluorescence leukotriene B4 assay for determining the activity of leukotriene A4 hydrolase

by Liang, Amy M, Claret, Emmanuel, Ouled-Diaf, Josy, Jean, Alexandre, Vogel, David, Light, David R, Jones, Steven W, Guilford, William J, Parkinson, John F, Snider, R Michael
Published in Journal of biomolecular screening (01.06.2007)

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Journal Article

Human Factor Xa Bound Amidine Inhibitor Conformation by Double Rotational-Echo Double Resonance Nuclear Magnetic Resonance and Molecular Dynamics Simulations

Human Factor Xa Bound Amidine Inhibitor Conformation by Double Rotational-Echo Double Resonance Nuclear Magnetic Resonance and Molecular Dynamics Simulations

by McDowell, Lynda M, McCarrick, Margaret A, Studelska, Daniel R, O'Connor, Robert D, Light, David R, Guilford, William J, Arnaiz, Damian, Adler, Marc, Dallas, Jerry L, Poliks, Barbara, Schaefer, Jacob
Published in Journal of medicinal chemistry (30.01.2003)

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Journal Article

Synthesis of 13C3,15N4-labeled factor Xa inhibitor

Synthesis of 13C3,15N4-labeled factor Xa inhibitor

by Guilford, William J., Dallas, Jerry, Arnaiz, Damian
Published in Journal of labelled compounds & radiopharmaceuticals (30.03.2001)

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