HER2YVMA drives rapid development of adenosquamous lung tumors in mice that are sensitive to BIBW2992 and rapamycin combination therapy
Perera, Samanthi A, Li, Danan, Shimamura, Takeshi, Raso, Maria G, Ji, Hongbin, Chen, Liang, Borgman, Christa L, Zaghlul, Sara, Brandstetter, Kathleyn A, Kubo, Shigeto, Takahashi, Masaya, Chirieac, Lucian R, Padera, Robert F, Bronson, Roderick T, Shapiro, Geoffrey I, Greulich, Heidi, Meyerson, Matthew, Guertler, Ulrich, Chesa, Pilar Garin, Solca, Flavio, Wistuba, Ignacio I, Wong, Kwok-Kin
Published in Proceedings of the National Academy of Sciences - PNAS (13.01.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (13.01.2009)
Get full text
Journal Article
BI 2536, a Potent and Selective Inhibitor of Polo-like Kinase 1, Inhibits Tumor Growth In Vivo
Steegmaier, Martin, Hoffmann, Matthias, Baum, Anke, Lénárt, Péter, Petronczki, Mark, Krššák, Martin, Gürtler, Ulrich, Garin-Chesa, Pilar, Lieb, Simone, Quant, Jens, Grauert, Matthias, Adolf, Günther R., Kraut, Norbert, Peters, Jan-Michael, Rettig, Wolfgang J.
Published in Current biology (20.02.2007)
Published in Current biology (20.02.2007)
Get full text
Journal Article
Pharmacological Profile of BI 847325, an Orally Bioavailable, ATP-Competitive Inhibitor of MEK and Aurora Kinases
Sini, Patrizia, Gürtler, Ulrich, Zahn, Stephan K, Baumann, Christoph, Rudolph, Dorothea, Baumgartinger, Rosa, Strauss, Eva, Haslinger, Christian, Tontsch-Grunt, Ulrike, Waizenegger, Irene C, Solca, Flavio, Bader, Gerd, Zoephel, Andreas, Treu, Matthias, Reiser, Ulrich, Garin-Chesa, Pilar, Boehmelt, Guido, Kraut, Norbert, Quant, Jens, Adolf, Günther R
Published in Molecular cancer therapeutics (01.10.2016)
Published in Molecular cancer therapeutics (01.10.2016)
Get full text
Journal Article
Discovery of novel amino-pyrimidine inhibitors of the insulin-like growth factor 1 (IGF1R) and insulin receptor (INSR) kinases; parallel optimization of cell potency and hERG inhibition
Tye, Heather, Guertler, Ulrich, Hofmann, Marco H., Mayer, Moriz, Pal, Sandeep, Rast, Georg, Sanderson, Michael P., Schaaf, Otmar, Treu, Matthias, Zahn, Stephan K.
Published in MedChemComm (01.01.2015)
Published in MedChemComm (01.01.2015)
Get full text
Journal Article
Discovery of novel amino-pyrimidine inhibitors of the insulin-like growth factor 1 (IGF1R) and insulin receptor (INSR) kinases; parallel optimization of cell potency and hERG inhibitionElectronic supplementary information (ESI) available: Details of synthetic procedures, in vitro assays and in vivo experiments. See DOI: 10.1039/c5md00097a
Tye, Heather, Guertler, Ulrich, Hofmann, Marco H, Mayer, Moriz, Pal, Sandeep, Rast, Georg, Sanderson, Michael P, Schaaf, Otmar, Treu, Matthias, Zahn, Stephan K
Year of Publication 08.07.2015
Year of Publication 08.07.2015
Get full text
Journal Article
ANTICANCER THERAPY WITH DUAL AURORA KINASE/MEK INHIBITORS
GUERTLER ULRICH, WAIZENEGGER IRENE, TONTSCH GRUNT ULRIKE, SOLCA FLAVIO, SANDERSON MICHAEL
Year of Publication 09.04.2014
Get full text
Year of Publication 09.04.2014
Patent
HER2^sup YVMA^ drives rapid development of adenosquamous lung tumors in mice that are sensitive to BIBW2992 and rapamycin combination therapy
Perera, Samanthi A, Li, Danan, Shimamura, Takeshi, Raso, Maria G, Ji, Hongbin, Chen, Liang, Borgman, Christa L, Zaghlul, Sara, Brandstetter, Kathleyn A, Kubo, Shigeto, Takahashi, Masaya, Chirieac, Lucian R, Padera, Robert F, Bronson, Roderick T, Shapiro, Geoffrey I, Greulich, Heidi, Meyerson, Matthew, Guertler, Ulrich, Chesa, Pilar Garin, Solca, Flavio, Wistuba, Ignacio I, Wong, Kwok-Kin
Published in Proceedings of the National Academy of Sciences - PNAS (13.01.2009)
Get full text
Published in Proceedings of the National Academy of Sciences - PNAS (13.01.2009)
Journal Article
HER2 YVMA drives rapid development of adenosquamous lung tumors in mice that are sensitive to BIBW2992 and rapamycin combination therapy
Perera, Samanthi A., Li, Danan, Shimamura, Takeshi, Raso, Maria G., Ji, Hongbin, Chen, Liang, Borgman, Christa L., Zaghlul, Sara, Brandstetter, Kathleyn A., Kubo, Shigeto, Takahashi, Masaya, Chirieac, Lucian R., Padera, Robert F., Bronson, Roderick T., Shapiro, Geoffrey I., Greulich, Heidi, Meyerson, Matthew, Guertler, Ulrich, Chesa, Pilar Garin, Solca, Flavio, Wistuba, Ignacio I., Wong, Kwok-Kin
Published in Proceedings of the National Academy of Sciences - PNAS (13.01.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (13.01.2009)
Get full text
Journal Article
ANTICANCER THERAPY
TONTSCH-GRUNT ULRIKE, GUERTLER ULRICH, WAIZENEGGER IRENE, SOLCA FLAVIO, SANDERSON MICHAEL
Year of Publication 10.07.2014
Get full text
Year of Publication 10.07.2014
Patent
2,4-DI(AMINOPHENYL)PYRIMIDINE DERIVATIVES AS PLK INHIBITORS
QUANT, Jens, Juergen, ENGELHARDT, Harald, STEEGMAIER, Martin, REISER, Ulrich, SCHOOP, Andreas, HERFURTH, Lars, SOLCA, Flavio, STADTMUELLER, Heinz, BAUM, Anke, GUERTLER, Ulrich, HAUPTMANN, Rudolf, ZAHN, Stephan Karl
Year of Publication 29.03.2016
Get full text
Year of Publication 29.03.2016
Patent
ANTICANCER THERAPY WITH DUAL AURORA KINASE / MEK INHIBITORS
GUERTLER, ULRICH, TONTSCH-GRUNT, ULRIKE, SANDERSON, MICHAEL, WAIZENEGGER, IRENE, SOLCA, FLAVIO
Year of Publication 20.11.2013
Get full text
Year of Publication 20.11.2013
Patent