Master Transcription Factors Determine Cell-Type-Specific Responses to TGF-β Signaling
Mullen, Alan C., Orlando, David A., Newman, Jamie J., Lovén, Jakob, Kumar, Roshan M., Bilodeau, Steve, Reddy, Jessica, Guenther, Matthew G., DeKoter, Rodney P., Young, Richard A.
Published in Cell (28.10.2011)
Published in Cell (28.10.2011)
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Journal Article
Quantitative ChIP-Seq Normalization Reveals Global Modulation of the Epigenome
Orlando, David A., Chen, Mei Wei, Brown, Victoria E., Solanki, Snehakumari, Choi, Yoon J., Olson, Eric R., Fritz, Christian C., Bradner, James E., Guenther, Matthew G.
Published in Cell reports (Cambridge) (06.11.2014)
Published in Cell reports (Cambridge) (06.11.2014)
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Journal Article
Divergent transcription of long noncoding RNA/mRNA gene pairs in embryonic stem cells
Sigova, Alla A., Mullen, Alan C., Molinie, Benoit, Gupta, Sumeet, Orlando, David A., Guenther, Matthew G., Almada, Albert E., Lin, Charles, Sharp, Phillip A., Giallourakis, Cosmas C., Young, Richard A.
Published in Proceedings of the National Academy of Sciences - PNAS (19.02.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (19.02.2013)
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Journal Article
A chromatin landmark and transcription initiation at most promoters in human cells
Guenther, Matthew G, Levine, Stuart S, Boyer, Laurie A, Jaenisch, Rudolf, Young, Richard A
Published in Cell (13.07.2007)
Published in Cell (13.07.2007)
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Journal Article
Chromatin Structure and Gene Expression Programs of Human Embryonic and Induced Pluripotent Stem Cells
Guenther, Matthew G., Frampton, Garrett M., Soldner, Frank, Hockemeyer, Dirk, Mitalipova, Maya, Jaenisch, Rudolf, Young, Richard A.
Published in Cell stem cell (06.08.2010)
Published in Cell stem cell (06.08.2010)
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Journal Article
Derivation of Pre-X Inactivation Human Embryonic Stem Cells under Physiological Oxygen Concentrations
Lengner, Christopher J., Gimelbrant, Alexander A., Erwin, Jennifer A., Cheng, Albert Wu, Guenther, Matthew G., Welstead, G. Grant, Alagappan, Raaji, Frampton, Garrett M., Xu, Ping, Muffat, Julien, Santagata, Sandro, Powers, Doug, Barrett, C. Brent, Young, Richard A., Lee, Jeannie T., Jaenisch, Rudolf, Mitalipova, Maisam
Published in Cell (28.05.2010)
Published in Cell (28.05.2010)
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Journal Article
Connecting microRNA Genes to the Core Transcriptional Regulatory Circuitry of Embryonic Stem Cells
Marson, Alexander, Levine, Stuart S., Cole, Megan F., Frampton, Garrett M., Brambrink, Tobias, Johnstone, Sarah, Guenther, Matthew G., Johnston, Wendy K., Wernig, Marius, Newman, Jamie, Calabrese, J. Mauro, Dennis, Lucas M., Volkert, Thomas L., Gupta, Sumeet, Love, Jennifer, Hannett, Nancy, Sharp, Phillip A., Bartel, David P., Jaenisch, Rudolf, Young, Richard A.
Published in Cell (08.08.2008)
Published in Cell (08.08.2008)
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Journal Article
Aberrant chromatin at genes encoding stem cell regulators in human mixed-lineage leukemia
Guenther, Matthew G, Lawton, Lee N, Rozovskaia, Tatiana, Frampton, Garrett M, Levine, Stuart S, Volkert, Thomas L, Croce, Carlo M, Nakamura, Tatsuya, Canaani, Eli, Young, Richard A
Published in Genes & development (15.12.2008)
Published in Genes & development (15.12.2008)
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Journal Article
Core Transcriptional Regulatory Circuitry in Human Embryonic Stem Cells
Boyer, Laurie A., Lee, Tong Ihn, Cole, Megan F., Johnstone, Sarah E., Levine, Stuart S., Zucker, Jacob P., Guenther, Matthew G., Kumar, Roshan M., Murray, Heather L., Jenner, Richard G., Gifford, David K., Melton, Douglas A., Jaenisch, Rudolf, Young, Richard A.
Published in Cell (23.09.2005)
Published in Cell (23.09.2005)
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Journal Article
Assembly of the SMRT-histone deacetylase 3 repression complex requires the TCP-1 ring complex
Guenther, Matthew G, Yu, Jiujiu, Kao, Gary D, Yen, Tim J, Lazar, Mitchell A
Published in Genes & development (15.12.2002)
Published in Genes & development (15.12.2002)
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Journal Article
Evidence that gene activation and silencing during stem cell differentiation requires a transcriptionally paused intermediate state
Golob, Jonathan L, Kumar, Roshan M, Guenther, Matthew G, Pabon, Lil M, Pratt, Gabriel A, Loring, Jeanne F, Laurent, Louise C, Young, Richard A, Murry, Charles E
Published in PloS one (19.08.2011)
Published in PloS one (19.08.2011)
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Journal Article
Genome-wide localization of small molecules
Anders, Lars, Guenther, Matthew G, Qi, Jun, Fan, Zi Peng, Marineau, Jason J, Rahl, Peter B, Lovén, Jakob, Sigova, Alla A, Smith, William B, Lee, Tong Ihn, Bradner, James E, Young, Richard A
Published in Nature biotechnology (01.01.2014)
Published in Nature biotechnology (01.01.2014)
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Journal Article
Superenhancer Analysis Defines Novel Epigenomic Subtypes of Non-APL AML, Including an RARα Dependency Targetable by SY-1425, a Potent and Selective RARα Agonist
McKeown, Michael R, Corces, M Ryan, Eaton, Matthew L, Fiore, Chris, Lee, Emily, Lopez, Jeremy T, Chen, Mei Wei, Smith, Darren, Chan, Steven M, Koenig, Julie L, Austgen, Kathryn, Guenther, Matthew G, Orlando, David A, Lovén, Jakob, Fritz, Christian C, Majeti, Ravindra
Published in Cancer discovery (01.10.2017)
Published in Cancer discovery (01.10.2017)
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Journal Article
ΔNp63/p73 drive metastatic colonization by controlling a regenerative epithelial stem cell program in quasi-mesenchymal cancer stem cells
Lambert, Arthur W., Fiore, Christopher, Chutake, Yogesh, Verhaar, Elisha R., Strasser, Patrick C., Chen, Mei Wei, Farouq, Daneyal, Das, Sunny, Li, Xin, Eaton, Elinor Ng, Zhang, Yun, Liu Donaher, Joana, Engstrom, Ian, Reinhardt, Ferenc, Yuan, Bingbing, Gupta, Sumeet, Wollison, Bruce, Eaton, Matthew, Bierie, Brian, Carulli, John, Olson, Eric R., Guenther, Matthew G., Weinberg, Robert A.
Published in Developmental cell (19.12.2022)
Published in Developmental cell (19.12.2022)
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Journal Article
Control of Developmental Regulators by Polycomb in Human Embryonic Stem Cells
Lee, Tong Ihn, Jenner, Richard G., Boyer, Laurie A., Guenther, Matthew G., Levine, Stuart S., Kumar, Roshan M., Chevalier, Brett, Johnstone, Sarah E., Cole, Megan F., Isono, Kyo-ichi, Koseki, Haruhiko, Fuchikami, Takuya, Abe, Kuniya, Murray, Heather L., Zucker, Jacob P., Yuan, Bingbing, Bell, George W., Herbolsheimer, Elizabeth, Hannett, Nancy M., Sun, Kaiming, Odom, Duncan T., Otte, Arie P., Volkert, Thomas L., Bartel, David P., Melton, Douglas A., Gifford, David K., Jaenisch, Rudolf, Young, Richard A.
Published in Cell (21.04.2006)
Published in Cell (21.04.2006)
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Journal Article
Repressive Transcription
Guenther, Matthew G., Young, Richard A.
Published in Science (American Association for the Advancement of Science) (09.07.2010)
Published in Science (American Association for the Advancement of Science) (09.07.2010)
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Journal Article
Histone Deacetylase Is a Direct Target of Valproic Acid, a Potent Anticonvulsant, Mood Stabilizer, and Teratogen
Phiel, Christopher J., Zhang, Fang, Huang, Eric Y., Guenther, Matthew G., Lazar, Mitchell A., Klein, Peter S.
Published in The Journal of biological chemistry (28.09.2001)
Published in The Journal of biological chemistry (28.09.2001)
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Journal Article
The SMRT and N-CoR Corepressors Are Activating Cofactors for Histone Deacetylase 3
Guenther, Matthew G., Barak, Orr, Lazar, Mitchell A.
Published in Molecular and Cellular Biology (01.09.2001)
Published in Molecular and Cellular Biology (01.09.2001)
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Journal Article