GSE4 peptide suppresses oxidative and telomere deficiencies in ataxia telangiectasia patient cells
Pintado-Berninches, Laura, Fernandez-Varas, Beatriz, Benitez-Buelga, Carlos, Manguan-Garcia, Cristina, Serrano-Benitez, Almudena, Iarriccio, Laura, Carrillo, Jaime, Guenechea, Guillermo, Egusquiaguirre, Susana P., Pedraz, Jose-Luis, Hernández, Rosa M., Igartua, Manoli, Arias-Salgado, Elena G., Cortés-Ledesma, Felipe, Sastre, Leandro, Perona, Rosario
Published in Cell death and differentiation (01.10.2019)
Published in Cell death and differentiation (01.10.2019)
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Generation of dyskeratosis congenita-like hematopoietic stem cells through the stable inhibition of DKC1
Carrascoso-Rubio, Carlos, Zittersteijn, Hidde A, Pintado-Berninches, Laura, Fernández-Varas, Beatriz, Lozano, M Luz, Manguan-Garcia, Cristina, Sastre, Leandro, Bueren, Juan A, Perona, Rosario, Guenechea, Guillermo
Published in Stem cell research & therapy (29.01.2021)
Published in Stem cell research & therapy (29.01.2021)
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A protocol describing the genetic correction of somatic human cells and subsequent generation of iPS cells
Belmonte, Juan Carlos Izpisúa, Raya, Ángel, Rodríguez-Pizà, Ignasi, Navarro, Susana, Richaud-Patin, Yvonne, Guenechea, Guillermo, Sánchez-Danés, Adriana, Consiglio, Antonella, Bueren, Juan
Published in Nature protocols (01.04.2010)
Published in Nature protocols (01.04.2010)
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Lentiviral-Mediated Gene Therapy in Fanconi Anemia-A Mice Reveals Long-Term Engraftment and Continuous Turnover of Corrected HSCs
Molina-Estevez, F Javier, Nowrouzi, Ali, Lozano, M Luz, Galy, Anne, Charrier, Sabine, von Kalle, Christof, Guenechea, Guillermo, Bueren, Juan A, Schmidt, Manfred
Published in Current gene therapy (01.01.2015)
Published in Current gene therapy (01.01.2015)
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Generation of a High Number of Healthy Erythroid Cells from Gene-Edited Pyruvate Kinase Deficiency Patient-Specific Induced Pluripotent Stem Cells
Garate, Zita, Quintana-Bustamante, Oscar, Crane, Ana M., Olivier, Emmanuel, Poirot, Laurent, Galetto, Roman, Kosinski, Penelope, Hill, Collin, Kung, Charles, Agirre, Xabi, Orman, Israel, Cerrato, Laura, Alberquilla, Omaira, Rodriguez-Fornes, Fatima, Fusaki, Noemi, Garcia-Sanchez, Felix, Maia, Tabita M., Ribeiro, Maria L., Sevilla, Julian, Prosper, Felipe, Jin, Shengfang, Mountford, Joanne, Guenechea, Guillermo, Gouble, Agnes, Bueren, Juan A., Davis, Brian R., Segovia, Jose C.
Published in Stem cell reports (08.12.2015)
Published in Stem cell reports (08.12.2015)
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Parvovirus Infection Suppresses Long-Term Repopulating Hematopoietic Stem Cells
Segovia, José C, Guenechea, Guillermo, Gallego, Jesús M, Almendral, José M, Bueren, Juan A
Published in Journal of Virology (01.08.2003)
Published in Journal of Virology (01.08.2003)
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Successful engraftment of gene-corrected hematopoietic stem cells in non-conditioned patients with Fanconi anemia
Río, Paula, Navarro, Susana, Wang, Wei, Sánchez-Domínguez, Rebeca, Pujol, Roser M., Segovia, José C., Bogliolo, Massimo, Merino, Eva, Wu, Ning, Salgado, Rocío, Lamana, María L., Yañez, Rosa M., Casado, José A., Giménez, Yari, Román-Rodríguez, Francisco J., Álvarez, Lara, Alberquilla, Omaira, Raimbault, Anna, Guenechea, Guillermo, Lozano, M. Luz, Cerrato, Laura, Hernando, Miriam, Gálvez, Eva, Hladun, Raquel, Giralt, Irina, Barquinero, Jordi, Galy, Anne, García de Andoín, Nagore, López, Ricardo, Catalá, Albert, Schwartz, Jonathan D., Surrallés, Jordi, Soulier, Jean, Schmidt, Manfred, Díaz de Heredia, Cristina, Sevilla, Julián, Bueren, Juan A.
Published in Nature medicine (01.09.2019)
Published in Nature medicine (01.09.2019)
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Disease-corrected haematopoietic progenitors from Fanconi anaemia induced pluripotent stem cells
Raya, Ángel, Rodríguez-Pizà, Ignasi, Guenechea, Guillermo, Vassena, Rita, Navarro, Susana, Barrero, María José, Consiglio, Antonella, Castellà, Maria, Río, Paula, Sleep, Eduard, González, Federico, Tiscornia, Gustavo, Garreta, Elena, Aasen, Trond, Veiga, Anna, Verma, Inder M., Surrallés, Jordi, Bueren, Juan, Belmonte, Juan Carlos Izpisúa
Published in Nature (London) (02.07.2009)
Published in Nature (London) (02.07.2009)
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Advances in the gene therapy of monogenic blood cell diseases
Bueren, Juan A., Quintana‐Bustamante, Oscar, Almarza, Elena, Navarro, Susana, Río, Paula, Segovia, José C., Guenechea, Guillermo
Published in Clinical genetics (01.01.2020)
Published in Clinical genetics (01.01.2020)
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Efficient Non-viral Gene Delivery into Human Hematopoietic Stem Cells by Minicircle Sleeping Beauty Transposon Vectors
Holstein, Marta, Mesa-Nuñez, Cristina, Miskey, Csaba, Almarza, Elena, Poletti, Valentina, Schmeer, Marco, Grueso, Esther, Ordóñez Flores, Juan Carlos, Kobelt, Dennis, Walther, Wolfgang, Aneja, Manish K., Geiger, Johannes, Bonig, Halvard B., Izsvák, Zsuzsanna, Schleef, Martin, Rudolph, Carsten, Mavilio, Fulvio, Bueren, Juan A., Guenechea, Guillermo, Ivics, Zoltán
Published in Molecular therapy (04.04.2018)
Published in Molecular therapy (04.04.2018)
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Engraftment and in vivo proliferation advantage of gene-corrected mobilized CD34+ cells from Fanconi anemia patients
Río, Paula, Navarro, Susana, Guenechea, Guillermo, Sánchez-Domínguez, Rebeca, Lamana, Maria Luisa, Yañez, Rosa, Casado, Jose A., Mehta, Parinda A., Pujol, Maria Roser, Surrallés, Jordi, Charrier, Sabine, Galy, Anne, Segovia, José C., Díaz de Heredia, Cristina, Sevilla, Julián, Bueren, Juan A.
Published in Blood (28.09.2017)
Published in Blood (28.09.2017)
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Conversion of Human Fibroblasts Into Monocyte‐Like Progenitor Cells
Pulecio, Julian, Nivet, Emmanuel, Sancho‐Martinez, Ignacio, Vitaloni, Marianna, Guenechea, Guillermo, Xia, Yun, Kurian, Leo, Dubova, Ilir, Bueren, Juan, Laricchia‐Robbio, Leopoldo, Belmonte, Juan Carlos Izpisua
Published in Stem cells (Dayton, Ohio) (01.11.2014)
Published in Stem cells (Dayton, Ohio) (01.11.2014)
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GSE4‐loaded nanoparticles a potential therapy for lung fibrosis that enhances pneumocyte growth, reduces apoptosis and DNA damage
Pintado‐Berninches, Laura, Montes‐Worboys, Ana, Manguan‐García, Cristina, Arias‐Salgado, Elena G., Serrano, Adela, Fernandez‐Varas, Beatriz, Guerrero‐López, Rosa, Iarriccio, Laura, Planas, Lurdes, Guenechea, Guillermo, Egusquiaguirre, Susana P., Hernandez, Rosa M., Igartua, Manoli, Luis Pedraz, Jose, Cortijo, Julio, Sastre, Leandro, Molina‐Molina, Maria, Perona, Rosario
Published in The FASEB journal (01.03.2021)
Published in The FASEB journal (01.03.2021)
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Mutations in XLF/NHEJ1/Cernunnos gene results in downregulation of telomerase genes expression and telomere shortening
Carrillo, Jaime, Calvete, Oriol, Pintado-Berninches, Laura, Manguan-García, Cristina, Sevilla Navarro, Julian, Arias-Salgado, Elena G, Sastre, Leandro, Guenechea, Guillermo, López Granados, Eduardo, de Villartay, Jean-Pierre, Revy, Patrick, Benitez, Javier, Perona, Rosario
Published in Human molecular genetics (15.05.2017)
Published in Human molecular genetics (15.05.2017)
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Distinct classes of human stem cells that differ in proliferative and self-renewal potential
Dick, John E, Guenechea, Guillermo, Gan, Olga I, Dorrell, Craig
Published in Nature immunology (01.01.2001)
Published in Nature immunology (01.01.2001)
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753. Lentiviral-Mediated Gene Correction of Mobilized Peripheral Blood Progenitors and Repopulating Cells from FA-A Patients
Río, Paula, Navarro, Susana, Guenechea, Guillermo, Galy, Anne, Sánchez, Rebeca, Lamana, María L., Yañez, Rosa, Casado, José A., Segovia, José C., Surrallés, Jordi, López, Ricardo, de Andoaín, Nagore García, Ruiz, Pedro, Catalá, Albert, de Heredia, Cristina Díaz, Sevilla, Julián, Bueren, Juan A.
Published in Molecular therapy (01.05.2016)
Published in Molecular therapy (01.05.2016)
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Brief Report: Impaired Cell Reprogramming in Nonhomologous End Joining Deficient Cells
Molina‐Estevez, F. Javier, Lozano, M. Luz, Navarro, Susana, Torres, Yaima, Grabundzija, Ivana, Ivics, Zoltan, Samper, Enrique, Bueren, Juan A., Guenechea, Guillermo
Published in Stem cells (Dayton, Ohio) (01.08.2013)
Published in Stem cells (Dayton, Ohio) (01.08.2013)
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