Serum C-reactive protein metabolite (CRPM) is associated with incidence of contralateral knee osteoarthritis
Bay-Jensen, Anne-Christine, Bihlet, Asger, Byrjalsen, Inger, Andersen, Jeppe Ragnar, Riis, Bente Juhl, Christiansen, Claus, Michaelis, Martin, Guehring, Hans, Ladel, Christoph, Karsdal, Morten A.
Published in Scientific reports (22.03.2021)
Published in Scientific reports (22.03.2021)
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Journal Article
99mTc-NTP 15-5 is a companion radiotracer for assessing joint functional response to sprifermin (rhFGF-18) in a murine osteoarthritis model
Briat, Arnaud, Jacques, Claire, Malige, Mélodie, Sudre, Laure, Nourissat, Geoffroy, Auzeloux, Philippe, Guehring, Hans, Cachin, Florent, Berenbaum, Francis, Miot-Noirault, Elisabeth
Published in Scientific reports (17.05.2022)
Published in Scientific reports (17.05.2022)
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Journal Article
Efficacy and safety results after >3.5 years of treatment with the Bruton’s tyrosine kinase inhibitor evobrutinib in relapsing multiple sclerosis: Long-term follow-up of a Phase II randomised clinical trial with a cerebrospinal fluid sub-study
Montalban, Xavier, Piasecka-Stryczynska, Karolina, Kuhle, Jens, Benkert, Pascal, Arnold, Douglas L, Weber, Martin S, Seitzinger, Andrea, Guehring, Hans, Shaw, Jamie, Tomic, Davorka, Hyvert, Yann, Harlow, Danielle E, Dyroff, Martin, Wolinsky, Jerry S
Published in Multiple sclerosis (01.04.2024)
Published in Multiple sclerosis (01.04.2024)
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Journal Article
Identification of Fibroblast Growth Factor-18 as a Molecule to Protect Adult Articular Cartilage by Gene Expression Profiling
Mori, Yoshifumi, Saito, Taku, Chang, Song Ho, Kobayashi, Hiroshi, Ladel, Christoph H., Guehring, Hans, Chung, Ung-il, Kawaguchi, Hiroshi
Published in The Journal of biological chemistry (04.04.2014)
Published in The Journal of biological chemistry (04.04.2014)
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Journal Article
Efficacy and Safety of the Bruton's Tyrosine Kinase Inhibitor Evobrutinib in Systemic Lupus Erythematosus: Results of a Phase II, Randomized, Double‐Blind, Placebo‐Controlled Dose‐Ranging Trial
Wallace, Daniel J., Dörner, Thomas, Pisetsky, David S., Sanchez‐Guerrero, Jorge, Patel, Anand C., Parsons‐Rich, Dana, Le Bolay, Claire, Drouin, Elise E., Kao, Amy H., Guehring, Hans, Dall'Era, Maria
Published in ACR open rheumatology (01.01.2023)
Published in ACR open rheumatology (01.01.2023)
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Journal Article
Safety, Tolerability, and Pharmacodynamics of the ADAMTS‐5 Nanobody M6495: Two Phase 1, Single‐Center, Double‐Blind, Randomized, Placebo‐Controlled Studies in Healthy Subjects and Patients With Osteoarthritis
Bihlet, Asger Reinstrup, Balchen, Torben, Goteti, Kosalaram, Sonne, Jesper, Ladel, Christoph, Karsdal, Morten Asser, Ona, Victor, Moreau, Flavie, Waterhouse, Roseann, Bay‐Jensen, Anne‐Christine, Guehring, Hans
Published in ACR open rheumatology (01.04.2024)
Published in ACR open rheumatology (01.04.2024)
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Journal Article
Inducible nitric oxide synthase is critical for immune-mediated liver injury in mice
Sass, G, Koerber, K, Bang, R, Guehring, H, Tiegs, G
Published in The Journal of clinical investigation (15.02.2001)
Published in The Journal of clinical investigation (15.02.2001)
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Journal Article
Osteochondral tissue engineering using a biphasic collagen/GAG scaffold containing rhFGF18 or BMP-7 in an ovine model
Getgood, Alan, Henson, Frances, Skelton, Carrie, Brooks, Roger, Guehring, Hans, Fortier, Lisa A, Rushton, Neil
Published in Journal of experimental orthopaedics (01.12.2014)
Published in Journal of experimental orthopaedics (01.12.2014)
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Journal Article
Effect of Intra-Articular Sprifermin vs Placebo on Femorotibial Joint Cartilage Thickness in Patients With Osteoarthritis: The FORWARD Randomized Clinical Trial
Hochberg, Marc C, Guermazi, Ali, Guehring, Hans, Aydemir, Aida, Wax, Stephen, Fleuranceau-Morel, Patricia, Reinstrup Bihlet, Asger, Byrjalsen, Inger, Ragnar Andersen, Jeppe, Eckstein, Felix
Published in JAMA : the journal of the American Medical Association (08.10.2019)
Published in JAMA : the journal of the American Medical Association (08.10.2019)
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Journal Article
Long-term structural and symptomatic effects of intra-articular sprifermin in patients with knee osteoarthritis: 5-year results from the FORWARD study
Eckstein, Felix, Hochberg, Marc C, Guehring, Hans, Moreau, Flavie, Ona, Victor, Bihlet, Asger Reinstrup, Byrjalsen, Inger, Andersen, Jeppe Ragnar, Daelken, Benjamin, Guenther, Oliver, Ladel, Christoph, Michaelis, Martin, Conaghan, Philip G
Published in Annals of the rheumatic diseases (01.08.2021)
Published in Annals of the rheumatic diseases (01.08.2021)
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Journal Article
Randomized Phase II JANUS Study of Atacicept in Patients With IgA Nephropathy and Persistent Proteinuria
Barratt, Jonathan, Tumlin, James, Suzuki, Yusuke, Kao, Amy, Aydemir, Aida, Pudota, Kishore, Jin, Hulin, Gühring, Hans, Appel, Gerald
Published in Kidney international reports (01.08.2022)
Published in Kidney international reports (01.08.2022)
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Journal Article
The effects of sprifermin on symptoms and structure in a subgroup at risk of progression in the FORWARD knee osteoarthritis trial
Guehring, Hans, Moreau, Flavie, Daelken, Benjamin, Ladel, Christoph, Guenther, Oliver, Bihlet, Asger Reinstrup, Wirth, Wolfgang, Eckstein, Felix, Hochberg, Marc, Conaghan, Philip G.
Published in Seminars in arthritis and rheumatism (01.04.2021)
Published in Seminars in arthritis and rheumatism (01.04.2021)
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Journal Article
Characterisation of the safety profile of evobrutinib in over 1000 patients from phase II clinical trials in multiple sclerosis, rheumatoid arthritis and systemic lupus erythematosus: an integrated safety analysis
Montalban, Xavier, Wallace, Daniel, Genovese, Mark C, Tomic, Davorka, Parsons-Rich, Dana, Le Bolay, Claire, Kao, Amy H, Guehring, Hans
Published in Journal of neurology, neurosurgery and psychiatry (01.01.2023)
Published in Journal of neurology, neurosurgery and psychiatry (01.01.2023)
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Journal Article
R399E, A Mutated Form of Growth and Differentiation Factor 5, for Disease Modification of Osteoarthritis
Gigout, Anne, Werkmann, Daniela, Menges, Stephanie, Brenneis, Christian, Henson, Frances, Cowan, Kyra J., Musil, Djordje, Thudium, Christian S., Gühring, Hans, Michaelis, Martin, Kleinschmidt‐Doerr, Kerstin
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.03.2023)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.03.2023)
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Journal Article
Safety and efficacy of evobrutinib in relapsing multiple sclerosis (evolutionRMS1 and evolutionRMS2): two multicentre, randomised, double-blind, active-controlled, phase 3 trials
Montalban, Xavier, Vermersch, Patrick, Arnold, Douglas L, Bar-Or, Amit, Cree, Bruce A C, Cross, Anne H, Kubala Havrdova, Eva, Kappos, Ludwig, Stuve, Olaf, Wiendl, Heinz, Wolinsky, Jerry S, Dahlke, Frank, Le Bolay, Claire, Shen Loo, Li, Gopalakrishnan, Sathej, Hyvert, Yann, Javor, Andrija, Guehring, Hans, Tenenbaum, Nadia, Tomic, Davorka
Published in Lancet neurology (01.11.2024)
Published in Lancet neurology (01.11.2024)
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