Preclinical characterization of ISB 1342, a CD38 × CD3 T-cell engager for relapsed/refractory multiple myeloma
Pouleau, Blandine, Estoppey, Carole, Suere, Perrine, Nallet, Emilie, Laurendon, Amélie, Monney, Thierry, Pais Ferreira, Daniela, Drake, Adam, Carretero-Iglesia, Laura, Macoin, Julie, Berret, Jérémy, Pihlgren, Maria, Doucey, Marie-Agnès, Gudi, Girish S., Menon, Vinu, Udupa, Venkatesha, Maiti, Abhishek, Borthakur, Gautam, Srivastava, Ankita, Blein, Stanislas, Mbow, M. Lamine, Matthes, Thomas, Kaya, Zeynep, Edwards, Claire M., Edwards, James R., Menoret, Emmanuelle, Kervoëlen, Charlotte, Pellat-Deceunynck, Catherine, Moreau, Philippe, Zhukovsky, Eugene, Perro, Mario, Chimen, Myriam
Published in Blood (20.07.2023)
Published in Blood (20.07.2023)
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Pre-clinical characterization of ISB 1342, a CD38xCD3 T-cell engager for relapsed/refractory multiple myeloma
Pouleau, Blandine, Estoppey, Carole, Suere, Perrine, Nallet, Emilie, Laurendon, Amélie, Monney, Thierry, Pais Ferreira, Daniela, Drake, Adam, Carretero-Iglesia, Laura, Macoin, Julie, Berret, Jeremy, Pihlgren, Maria, Doucey, Marie-Agnes, Gudi, Girish S, Menon, Vinu, Udupa, Venkatesha, Maiti, Abhishek, Borthakur, Gautam, Srivastava, Ankita, Blein, Stanislas, Mbow, Lamine, Matthes, Thomas, Kaya, Zeynep, Edwards, Claire M, Edwards, James R, Menoret, Emmanuelle, Kervoelen, Charlotte, Pellat-Deceunynck, Catherine, Moreau, Philippe, Zhukovsky, Eugene Alexander, Perro, Mario, Chimen, Myriam
Published in Blood (16.05.2023)
Published in Blood (16.05.2023)
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Single-step Protein A and Protein G avidity purification methods to support bispecific antibody discovery and development
Ollier, Romain, Wassmann, Paul, Monney, Thierry, Ries Fecourt, Christelle, Gn, Sunitha, C A, Vinu, Ayoub, Daniel, Stutz, Cian, Gudi, Girish S, Blein, Stanislas
Published in mAbs (17.11.2019)
Published in mAbs (17.11.2019)
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Discovery of 5-(2-chloro-4′-(1H-imidazol-1-yl)-[1,1′-biphenyl]-4-yl)-1H-tetrazole as potent and orally efficacious S-nitrosoglutathione reductase (GSNOR) inhibitors for the potential treatment of COPD
Muthukaman, Nagarajan, Deshmukh, Sanjay, Tondlekar, Shital, Tambe, Macchindra, Pisal, Dnyandeo, Sarode, Neelam, Mhatre, Siddharth, Chakraborti, Samitabh, Shah, Daisy, Bhosale, Vikram M., Kulkarni, Abhay, Mahat, Mahamad Yunnus A., Jadhav, Satyawan B., Gudi, Girish S., Khairatkar-Joshi, Neelima, Gharat, Laxmikant A.
Published in Bioorganic & medicinal chemistry letters (15.12.2018)
Published in Bioorganic & medicinal chemistry letters (15.12.2018)
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Alleviating CYP and hERG liabilities by structure optimization of dihydrofuran-fused tricyclic benzo[d]imidazole series – Potent, selective and orally efficacious microsomal prostaglandin E synthase-1 (mPGES-1) inhibitors: Part-2
Muthukaman, Nagarajan, Deshmukh, Sanjay, Tambe, Macchindra, Pisal, Dnyandeo, Tondlekar, Shital, Shaikh, Mahamadhanif, Sarode, Neelam, Kattige, Vidya G., Sawant, Pooja, Pisat, Monali, Karande, Vikas, Honnegowda, Srinivasa, Kulkarni, Abhay, Behera, Dayanidhi, Jadhav, Satyawan B., Sangana, Ramchandra R., Gudi, Girish S., Khairatkar-Joshi, Neelima, Gharat, Laxmikant A.
Published in Bioorganic & medicinal chemistry letters (15.04.2018)
Published in Bioorganic & medicinal chemistry letters (15.04.2018)
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Discovery of furan and dihydrofuran-fused tricyclic benzo[d]imidazole derivatives as potent and orally efficacious microsomal prostaglandin E synthase-1 (mPGES-1) inhibitors: Part-1
Muthukaman, Nagarajan, Tambe, Macchindra, Deshmukh, Sanjay, Pisal, Dnyandeo, Tondlekar, Shital, Shaikh, Mahamadhanif, Sarode, Neelam, Kattige, Vidya G., Pisat, Monali, Sawant, Pooja, Honnegowda, Srinivasa, Karande, Vikas, Kulkarni, Abhay, Behera, Dayanidhi, Jadhav, Satyawan B., Sangana, Ramchandra R., Gudi, Girish S., Khairatkar-Joshi, Neelima, Gharat, Laxmikant A.
Published in Bioorganic & medicinal chemistry letters (01.12.2017)
Published in Bioorganic & medicinal chemistry letters (01.12.2017)
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Design, Synthesis, and Pharmacological Evaluation of 5,6-Disubstituted Pyridin-2(1H)‑one Derivatives as Phosphodiesterase 10A (PDE10A) Antagonists
Lingam, V. S. Prasadarao, Dahale, Dnyaneshwar H, Rathi, Vijay E, Shingote, Yogesh B, Thakur, Rajni R, Mindhe, Ajit S, Kummari, Srinivas, Khairatkar-Joshi, Neelima, Bajpai, Malini, Shah, Daisy M, Sapalya, Ratika S, Gullapalli, Srinivas, Gupta, Praveen K, Gudi, Girish S, Jadhav, Satyawan B, Pattem, Rambabu, Thomas, Abraham
Published in Journal of medicinal chemistry (22.10.2015)
Published in Journal of medicinal chemistry (22.10.2015)
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Tricyclic 4,4-dimethyl-3,4-dihydrochromeno[3,4-d]imidazole derivatives as microsomal prostaglandin E-2 synthase-1 (mPGES-1) inhibitors: SAR and in vivo efficacy in hyperalgesia pain model
Muthukaman, Nagarajan, Tambe, Macchindra, Shaikh, Mahamadhanif, Pisal, Dnyandeo, Deshmukh, Sanjay, Tondlekar, Shital, Sarode, Neelam, Narayana, Lakshminarayana, Gajera, Jitendra M., Kattige, Vidya G., Honnegowda, Srinivasa, Karande, Vikas, Kulkarni, Abhay, Behera, Dayanidhi, Jadhav, Satyawan B., Gudi, Girish S., Khairatkar-Joshi, Neelima, Gharat, Laxmikant A.
Published in Bioorganic & medicinal chemistry letters (01.06.2017)
Published in Bioorganic & medicinal chemistry letters (01.06.2017)
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Tricyclic 4,4-dimethyl-3,4-dihydrochromeno[3,4-d]imidazole derivatives as microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitors: SAR and in vivo efficacy in hyperalgesia pain model
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Published in Bioorganic & medicinal chemistry letters (01.06.2017)
Published in Bioorganic & medicinal chemistry letters (01.06.2017)
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Discovery of 2-(2-chloro-6-fluorophenyl)amino)-N-(3-fluoro-5-(trifluoromethyl)phenyl)-1-methyl-7,8-dihydro-1H-[1,4]dioxino [2 ',3 ':3,4]benzo[1,2-d]imidazole-5-carboxamide as potent, selective and efficacious microsomal prostaglandin E-2 synthase-1 (mPGES-1) inhibitor
Muthukaman, Nagarajan, Deshmukh, Sanjay, Sarode, Neelam, Tondlekar, Shital, Tambe, Macchindra, Pisal, Dnyandeo, Shaikh, Mahamadhanif, Kattige, Vidya G., Honnegowda, Srinivasa, Karande, Vikas, Kulkarni, Abhay, Jadhav, Satyawan B., Mahat, Mahamad Yunnus A., Gudi, Girish S., Khairatkar-Joshi, Neelima, Gharat, Laxmikant A.
Published in Bioorganic & medicinal chemistry letters (15.12.2016)
Published in Bioorganic & medicinal chemistry letters (15.12.2016)
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Phase 2b randomized trial of OX40 inhibitor telazorlimab for moderate-to-severe atopic dermatitis
Rewerska, Barbara, Sher, Lawrence D., Alpizar, Sady, Pauser, Sylvia, Pulka, Grazyna, Mozaffarian, Neelufar, Salhi, Yacine, Martinet, Camille, Jabert, Wafaa, Gudi, Girish, CA, Vinu, GN, Sunitha, Macoin, Julie, Anstett, Victor, Turrini, Riccardo, Doucey, Marie-Agnès, Blein, Stanislas, Konto, Cyril, Machkova, Martina
Published in The journal of allergy and clinical immunology. Global (01.02.2024)
Published in The journal of allergy and clinical immunology. Global (01.02.2024)
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Synthesis and pharmacological evaluation of novel N-aryl-3,4-dihydro-1′H-spiro[chromene-2,4′-piperidine]-1′-carboxamides as TRPM8 antagonists
Chaudhari, Sachin S., Kadam, Ashok B., Khairatkar-Joshi, Neelima, Mukhopadhyay, Indranil, Karnik, Pallavi V., Raghuram, Anupindi, Rao, Shobha S., Vaiyapuri, Thamil Selvan, Wale, Dinesh P., Bhosale, Vikram M., Gudi, Girish S., Sangana, Ramchandra R., Thomas, Abraham
Published in Bioorganic & medicinal chemistry (01.11.2013)
Published in Bioorganic & medicinal chemistry (01.11.2013)
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Imidazopyridazinones as novel PDE7 inhibitors: SAR and in vivo studies in Parkinson’s disease model
Banerjee, Abhisek, Patil, Sandip, Pawar, Mahesh Y., Gullapalli, Srinivas, Gupta, Praveen K., Gandhi, Maulik N., Bhateja, Deepak K., Bajpai, Malini, Sangana, Ramachandra Rao, Gudi, Girish S., Khairatkar-Joshi, Neelima, Gharat, Laxmikant A.
Published in Bioorganic & medicinal chemistry letters (01.10.2012)
Published in Bioorganic & medicinal chemistry letters (01.10.2012)
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Journal Article
Discovery of benzo[d]imidazo[5,1-b]thiazole as a new class of phosphodiesterase 10A inhibitors
Banerjee, Abhisek, Narayana, Lakshminarayana, Raje, Firoj A., Pisal, Dnyandeo V., Kadam, Pradip A., Gullapalli, Srinivas, Kumar, Hemant, More, Sandeep V., Bajpai, Malini, Sangana, Ramachandra Rao, Jadhav, Satyawan, Gudi, Girish S., Khairatkar-Joshi, Neelima, Merugu, Ravi R.T., Voleti, Sreedhara R., Gharat, Laxmikant A.
Published in Bioorganic & medicinal chemistry letters (15.12.2013)
Published in Bioorganic & medicinal chemistry letters (15.12.2013)
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Journal Article
Discovery of 2-((2-chloro-6-fluorophenyl)amino)-N-(3-fluoro-5-(trifluoromethyl)phenyl)-1-methyl-7,8-dihydro-1H-[1,4]dioxino[2′,3′:3,4]benzo[1,2-d]imidazole-5-carboxamide as potent, selective and efficacious microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitor
Muthukaman, Nagarajan, Deshmukh, Sanjay, Sarode, Neelam, Tondlekar, Shital, Tambe, Macchindra, Pisal, Dnyandeo, Shaikh, Mahamadhanif, Kattige, Vidya G., Honnegowda, Srinivasa, Karande, Vikas, Kulkarni, Abhay, Jadhav, Satyawan B., Mahat, Mahamad Yunnus A., Gudi, Girish S., Khairatkar-Joshi, Neelima, Gharat, Laxmikant A.
Published in Bioorganic & medicinal chemistry letters (15.12.2016)
Published in Bioorganic & medicinal chemistry letters (15.12.2016)
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Design, synthesis and pharmacological evaluation of novel polycyclic heteroarene ethers as PDE10A inhibitors: Part I
Das, Sanjib, Harde, Rajendra L., Shelke, Dnyaneshwar E., Khairatkar-Joshi, Neelima, Bajpai, Malini, Sapalya, Ratika S., Surve, Harshada V., Gudi, Girish S., Pattem, Rambabu, Behera, Dayanidhi B., Jadhav, Satyawan B., Thomas, Abraham
Published in Bioorganic & medicinal chemistry letters (01.05.2014)
Published in Bioorganic & medicinal chemistry letters (01.05.2014)
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Journal Article
Isothiazole and isoxazole fused pyrimidones as PDE7 inhibitors: SAR and pharmacokinetic evaluation
Banerjee, Abhisek, Yadav, Pravin S., Bajpai, Malini, Sangana, Ramachandra Rao, Gullapalli, Srinivas, Gudi, Girish S., Gharat, Laxmikant A.
Published in Bioorganic & medicinal chemistry letters (01.05.2012)
Published in Bioorganic & medicinal chemistry letters (01.05.2012)
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Journal Article
Design, synthesis and pharmacological evaluation of novel polycyclic heteroarene ethers as PDE10A inhibitors: Part II
Das, Sanjib, Shelke, Dnyaneshwar E., Harde, Rajendra L., Avhad, Vijayshree B., Khairatkar-Joshi, Neelima, Gullapalli, Srinivas, Gupta, Praveen K., Gandhi, Maulik N., Bhateja, Deepak K., Bajpai, Malini, Joshi, Ashwini A., Marathe, Megha Y., Gudi, Girish S., Jadhav, Satyawan B., Mahat, Mahamad Yunnus A., Thomas, Abraham
Published in Bioorganic & medicinal chemistry letters (01.08.2014)
Published in Bioorganic & medicinal chemistry letters (01.08.2014)
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