GalNAc Conjugation Attenuates the Cytotoxicity of Antisense Oligonucleotide Drugs in Renal Tubular Cells
Sewing, Sabine, Gubler, Marcel, Gérard, Régine, Avignon, Blandine, Mueller, Yasmin, Braendli-Baiocco, Annamaria, Odin, Marielle, Moisan, Annie
Published in Molecular therapy. Nucleic acids (01.03.2019)
Published in Molecular therapy. Nucleic acids (01.03.2019)
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Determination of Protein–Ligand Binding Constants of a Cooperatively Regulated Tetrameric Enzyme Using Electrospray Mass Spectrometry
Cubrilovic, Dragana, Haap, Wolfgang, Barylyuk, Konstantin, Ruf, Armin, Badertscher, Martin, Gubler, Marcel, Tetaz, Tim, Joseph, Catherine, Benz, Jörg, Zenobi, Renato
Published in ACS chemical biology (17.01.2014)
Published in ACS chemical biology (17.01.2014)
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Inhibition of EGF Uptake by Nephrotoxic Antisense Drugs In Vitro and Implications for Preclinical Safety Profiling
Moisan, Annie, Gubler, Marcel, Zhang, Jitao David, Tessier, Yann, Dumong Erichsen, Kamille, Sewing, Sabine, Gérard, Régine, Avignon, Blandine, Huber, Sylwia, Benmansour, Fethallah, Chen, Xing, Villaseñor, Roberto, Braendli-Baiocco, Annamaria, Festag, Matthias, Maunz, Andreas, Singer, Thomas, Schuler, Franz, Roth, Adrian B.
Published in Molecular therapy. Nucleic acids (17.03.2017)
Published in Molecular therapy. Nucleic acids (17.03.2017)
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Immune-infiltrated kidney organoid-on-chip model for assessing T cell bispecific antibodies
Kroll, Katharina T, Mata, Mariana M, Homan, Kimberly A, Micallef, Virginie, Carpy, Alejandro, Hiratsuka, Ken, Morizane, Ryuji, Moisan, Annie, Gubler, Marcel, Walz, Antje-Christine, Marrer-Berger, Estelle, Lewis, Jennifer A
Published in Proceedings of the National Academy of Sciences - PNAS (29.08.2023)
Published in Proceedings of the National Academy of Sciences - PNAS (29.08.2023)
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Allosteric FBPase inhibitors gain 10(5) times in potency when simultaneously binding two neighboring AMP sites
Hebeisen, Paul, Kuhn, Bernd, Kohler, Philipp, Gubler, Marcel, Huber, Walter, Kitas, Eric, Schott, Brigitte, Benz, Jörg, Joseph, Catherine, Ruf, Armin
Published in Bioorganic & medicinal chemistry letters (15.08.2008)
Published in Bioorganic & medicinal chemistry letters (15.08.2008)
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The direct effect of leptin on skeletal muscle thermogenesis is mediated by substrate cycling between de novo lipogenesis and lipid oxidation
Solinas, Giovanni, Summermatter, Serge, Mainieri, Davide, Gubler, Marcel, Pirola, Luciano, Wymann, Matthias P., Rusconi, Sandro, Montani, Jean-Pierre, Seydoux, Josiane, Dulloo, Abdul G.
Published in FEBS letters (19.11.2004)
Published in FEBS letters (19.11.2004)
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Sulfonylureido thiazoles as fructose-1,6-bisphosphatase inhibitors for the treatment of Type-2 diabetes
Kitas, Eric, Mohr, Peter, Kuhn, Bernd, Hebeisen, Paul, Wessel, Hans Peter, Haap, Wolfgang, Ruf, Armin, Benz, Jörg, Joseph, Catherine, Huber, Walter, Sanchez, Ruben Alvarez, Paehler, Axel, Benardeau, Agnes, Gubler, Marcel, Schott, Brigitte, Tozzo, Effie
Published in Bioorganic & medicinal chemistry letters (15.01.2010)
Published in Bioorganic & medicinal chemistry letters (15.01.2010)
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HepG2/C3A 3D spheroids exhibit stable physiological functionality for at least 24 days after recovering from trypsinisation
Wrzesinski, Krzysztof, Magnone, Maria Chiara, Hansen, Line Visby, Kruse, Marianne Ehrhorn, Bergauer, Tobias, Bobadilla, Maria, Gubler, Marcel, Mizrahi, Jacques, Zhang, Kelan, Andreasen, Christina M., Joensen, Kira Eyð, Andersen, Signe Marie, Olesen, Jacob Bastholm, Schaffalitzky de Muckadell, Ove B., Fey, Stephen J.
Published in Toxicology research (Cambridge) (01.01.2013)
Published in Toxicology research (Cambridge) (01.01.2013)
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Orally active aminopyridines as inhibitors of tetrameric fructose-1,6-bisphosphatase
Hebeisen, Paul, Haap, Wolfgang, Kuhn, Bernd, Mohr, Peter, Wessel, Hans Peter, Zutter, Ulrich, Kirchner, Stephan, Ruf, Armin, Benz, Jörg, Joseph, Catherine, Alvarez-Sánchez, Rubén, Gubler, Marcel, Schott, Brigitte, Benardeau, Agnes, Tozzo, Effie, Kitas, Eric
Published in Bioorganic & medicinal chemistry letters (01.06.2011)
Published in Bioorganic & medicinal chemistry letters (01.06.2011)
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Allosteric FBPase inhibitors gain 10 super(5) times in potency when simultaneously binding two neighboring AMP sites
Hebeisen, Paul, Kuhn, Bernd, Kohler, Philipp, Gubler, Marcel, Huber, Walter, Kitas, Eric, Schott, Brigitte, Benz, Joerg, Joseph, Catherine, Ruf, Armin
Published in Bioorganic & medicinal chemistry (01.08.2008)
Published in Bioorganic & medicinal chemistry (01.08.2008)
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Allosteric FBPase inhibitors gain 105 times in potency when simultaneously binding two neighboring AMP sites
HEBEISEN, Paul, KUHN, Bernd, KOHLER, Philipp, GUBLER, Marcel, HUBER, Walter, KITAS, Eric, SCHOTT, Brigitte, BENZ, Jörg, JOSEPH, Catherine, RUF, Armin
Published in Bioorganic & medicinal chemistry letters (01.08.2008)
Published in Bioorganic & medicinal chemistry letters (01.08.2008)
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Corticotropin-Releasing Hormone Directly Stimulates Thermogenesis in Skeletal Muscle Possibly through Substrate Cycling between de Novo Lipogenesis and Lipid Oxidation
Solinas, G, Summermatter, S, Mainieri, D, Gubler, M, Montani, J. P, Seydoux, J, Smith, S. R, Dulloo, A. G
Published in Endocrinology (Philadelphia) (01.01.2006)
Published in Endocrinology (Philadelphia) (01.01.2006)
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Journal Article
Allosteric FBPase inhibitors gain 10 5 times in potency when simultaneously binding two neighboring AMP sites
Hebeisen, Paul, Kuhn, Bernd, Kohler, Philipp, Gubler, Marcel, Huber, Walter, Kitas, Eric, Schott, Brigitte, Benz, Jörg, Joseph, Catherine, Ruf, Armin
Published in Bioorganic & medicinal chemistry letters (2008)
Published in Bioorganic & medicinal chemistry letters (2008)
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