Regulation of the Hippo pathway and implications for anticancer drug development
Park, Hyun Woo, Guan, Kun-Liang
Published in Trends in pharmacological sciences (Regular ed.) (01.10.2013)
Published in Trends in pharmacological sciences (Regular ed.) (01.10.2013)
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Journal Article
ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase
Russell, Ryan C., Tian, Ye, Yuan, Haixin, Park, Hyun Woo, Chang, Yu-Yun, Kim, Joungmok, Kim, Haerin, Neufeld, Thomas P., Dillin, Andrew, Guan, Kun-Liang
Published in Nature cell biology (01.07.2013)
Published in Nature cell biology (01.07.2013)
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Journal Article
Flow-dependent YAP/TAZ activities regulate endothelial phenotypes and atherosclerosis
Wang, Kuei-Chun, Yeh, Yi-Ting, Nguyen, Phu, Limqueco, Elaine, Lopez, Jocelyn, Thorossian, Satenick, Guan, Kun-Liang, Li, Yi-Shuan J., Chien, Shu
Published in Proceedings of the National Academy of Sciences - PNAS (11.10.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (11.10.2016)
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Journal Article
Cell detachment activates the Hippo pathway via cytoskeleton reorganization to induce anoikis
Zhao, Bin, Li, Li, Wang, Lloyd, Wang, Cun-Yu, Yu, Jindan, Guan, Kun-Liang
Published in Genes & development (01.01.2012)
Published in Genes & development (01.01.2012)
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Journal Article
A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP)
Zhao, Bin, Li, Li, Tumaneng, Karen, Wang, Cun-Yu, Guan, Kun-Liang
Published in Genes & development (01.01.2010)
Published in Genes & development (01.01.2010)
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Journal Article
SIRT3-dependent GOT2 acetylation status affects the malate-aspartate NADH shuttle activity and pancreatic tumor growth
Yang, Hui, Zhou, Lisha, Shi, Qian, Zhao, Yuzheng, Lin, Huaipeng, Zhang, Mengli, Zhao, Shimin, Yang, Yi, Ling, Zhi-Qiang, Guan, Kun-Liang, Xiong, Yue, Ye, Dan
Published in The EMBO journal (15.04.2015)
Published in The EMBO journal (15.04.2015)
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Journal Article
The Hippo signalling pathway and its implications in human health and diseases
Fu, Minyang, Hu, Yuan, Lan, Tianxia, Guan, Kun-Liang, Luo, Ting, Luo, Min
Published in Signal transduction and targeted therapy (08.11.2022)
Published in Signal transduction and targeted therapy (08.11.2022)
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Journal Article
Small Molecule Inhibitors of TEAD Auto-palmitoylation Selectively Inhibit Proliferation and Tumor Growth of NF2 -deficient Mesothelioma
Tang, Tracy T, Konradi, Andrei W, Feng, Ying, Peng, Xiao, Ma, Mingyue, Li, Jian, Yu, Fa-Xing, Guan, Kun-Liang, Post, Leonard
Published in Molecular cancer therapeutics (01.06.2021)
Published in Molecular cancer therapeutics (01.06.2021)
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Journal Article
Rag GTPases regulate cellular amino acid homeostasis
Inoki, Ken, Guan, Kun-Liang
Published in Proceedings of the National Academy of Sciences - PNAS (22.02.2022)
Published in Proceedings of the National Academy of Sciences - PNAS (22.02.2022)
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Journal Article
Amino Acids License Kinase mTORC1 Activity and Treg Cell Function via Small G Proteins Rag and Rheb
Shi, Hao, Chapman, Nicole M., Wen, Jing, Guy, Cliff, Long, Lingyun, Dhungana, Yogesh, Rankin, Sherri, Pelletier, Stephane, Vogel, Peter, Wang, Hong, Peng, Junmin, Guan, Kun-Liang, Chi, Hongbo
Published in Immunity (Cambridge, Mass.) (17.12.2019)
Published in Immunity (Cambridge, Mass.) (17.12.2019)
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Journal Article
SIRT5 inhibits peroxisomal ACOX1 to prevent oxidative damage and is downregulated in liver cancer
Chen, Xiu‐Fei, Tian, Meng‐Xin, Sun, Ren‐Qiang, Zhang, Meng‐Li, Zhou, Li‐Sha, Jin, Lei, Chen, Lei‐Lei, Zhou, Wen‐Jie, Duan, Kun‐Long, Chen, Yu‐Jia, Gao, Chao, Cheng, Zhou‐Li, Wang, Fang, Zhang, Jin‐Ye, Sun, Yi‐Ping, Yu, Hong‐Xiu, Zhao, Yu‐Zheng, Yang, Yi, Liu, Wei‐Ren, Shi, Ying‐Hong, Xiong, Yue, Guan, Kun‐Liang, Ye, Dan
Published in EMBO reports (01.05.2018)
Published in EMBO reports (01.05.2018)
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Journal Article
Heat stress activates YAP/TAZ to induce the heat shock transcriptome
Luo, Min, Meng, Zhipeng, Moroishi, Toshiro, Lin, Kimberly C., Shen, Guobo, Mo, Fei, Shao, Bin, Wei, Xiawei, Zhang, Ping, Wei, Yuquan, Guan, Kun-Liang
Published in Nature cell biology (01.12.2020)
Published in Nature cell biology (01.12.2020)
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Journal Article
Acetylation accumulates PFKFB3 in cytoplasm to promote glycolysis and protects cells from cisplatin-induced apoptosis
Li, Fu-Long, Liu, Jin-Ping, Bao, Ruo-Xuan, Yan, GuoQuan, Feng, Xu, Xu, Yan-Ping, Sun, Yi-Ping, Yan, Weili, Ling, Zhi-Qiang, Xiong, Yue, Guan, Kun-Liang, Yuan, Hai-Xin
Published in Nature communications (06.02.2018)
Published in Nature communications (06.02.2018)
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Journal Article
Metabolic reprogramming by PCK1 promotes TCA cataplerosis, oxidative stress and apoptosis in liver cancer cells and suppresses hepatocellular carcinoma
Liu, Meng-Xi, Jin, Lei, Sun, Si-Jia, Liu, Peng, Feng, Xu, Cheng, Zhou-Li, Liu, Wei-Ren, Guan, Kun-Liang, Shi, Ying-Hong, Yuan, Hai-Xin, Xiong, Yue
Published in Oncogene (01.03.2018)
Published in Oncogene (01.03.2018)
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Journal Article
The Hippo pathway effector proteins YAP and TAZ have both distinct and overlapping functions in the cell
Plouffe, Steven W., Lin, Kimberly C., Moore, Jerrell L., Tan, Frederick E., Ma, Shenghong, Ye, Zhen, Qiu, Yunjiang, Ren, Bing, Guan, Kun-Liang
Published in The Journal of biological chemistry (13.07.2018)
Published in The Journal of biological chemistry (13.07.2018)
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Journal Article
Structural insights into TSC complex assembly and GAP activity on Rheb
Yang, Huirong, Yu, Zishuo, Chen, Xizi, Li, Jiabei, Li, Ningning, Cheng, Jiaxuan, Gao, Ning, Yuan, Hai-Xin, Ye, Dan, Guan, Kun-Liang, Xu, Yanhui
Published in Nature communications (12.01.2021)
Published in Nature communications (12.01.2021)
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Journal Article
Differential Regulation of Distinct Vps34 Complexes by AMPK in Nutrient Stress and Autophagy
Kim, Joungmok, Kim, Young Chul, Fang, Chong, Russell, Ryan C., Kim, Jeong Hee, Fan, Weiliang, Liu, Rong, Zhong, Qing, Guan, Kun-Liang
Published in Cell (17.01.2013)
Published in Cell (17.01.2013)
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