Discoidin domain receptor 2 germline gene deletion leads to altered heart structure and function in the mouse
Cowling, Randy T, Yeo, Seon Ju, Kim, In Jai, Park, Joong Il, Gu, Yusu, Dalton, Nancy D, Peterson, Kirk L, Greenberg, Barry H
Published in American journal of physiology. Heart and circulatory physiology (01.09.2014)
Published in American journal of physiology. Heart and circulatory physiology (01.09.2014)
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ErbB2 is essential in the prevention of dilated cardiomyopathy
Lee, Kuo-Fen, Crone, Steven A, Zhao, You-Yang, Fan, Lian, Gu, Yusu, Minamisawa, Susumu, Liu, Yang, Peterson, Kirk L, Chen, Ju, Kahn, Ronald, Condorelli, Gianluigi, Jr, John Ross, Chien, Kenneth R
Published in Nature medicine (01.05.2002)
Published in Nature medicine (01.05.2002)
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β1 Integrin Gene Excision in the Adult Murine Cardiac Myocyte Causes Defective Mechanical and Signaling Responses
Li, Ruixia, Wu, Ying, Manso, Ana Maria, Gu, Yusu, Liao, Peter, Israeli, Sharon, Yajima, Toshitaka, Nguyen, Uyen, Huang, Michael S, Dalton, Nancy D, Peterson, Kirk L, Ross, Robert S
Published in The American journal of pathology (01.03.2012)
Published in The American journal of pathology (01.03.2012)
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Defects in caveolin-1 Cause Dilated Cardiomyopathy and Pulmonary Hypertension in Knockout Mice
Zhao, You-Yang, Liu, Yang, Stan, Radu-Virgil, Fan, Lian, Gu, Yusu, Dalton, Nancy, Chu, Po-Hsien, Peterson, Kirk, Ross, John, Chien, Kenneth R.
Published in Proceedings of the National Academy of Sciences - PNAS (20.08.2002)
Published in Proceedings of the National Academy of Sciences - PNAS (20.08.2002)
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Akt Induces Enhanced Myocardial Contractility and Cell Size in vivo in Transgenic Mice
Condorelli, Gianluigi, Drusco, Alessandra, Stassi, Giorgio, Bellacosa, Alfonso, Roncarati, Roberta, Iaccarino, Guido, Russo, Matteo A., Gu, Yusu, Dalton, Nancy, Chung, Clarence, Michael V. G. Latronico, Napoli, Claudio, Sadoshima, Junichi, Croce, Carlo M., Ross, John
Published in Proceedings of the National Academy of Sciences - PNAS (17.09.2002)
Published in Proceedings of the National Academy of Sciences - PNAS (17.09.2002)
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Selective Life-Long Skeletal Myofiber-Targeted VEGF Gene Ablation Impairs Exercise Capacity in Adult Mice
Tang, Kechun, Gu, Yusu, Dalton, Nancy D., Wagner, Harrieth, Peterson, Kirk L., Wagner, Peter D., Breen, Ellen C.
Published in Journal of cellular physiology (01.02.2016)
Published in Journal of cellular physiology (01.02.2016)
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Cardiac-specific ablation of Cypher leads to a severe form of dilated cardiomyopathy with premature death
Zheng, Ming, Cheng, Hongqiang, Li, Xiaodong, Zhang, Jianlin, Cui, Li, Ouyang, Kunfu, Han, Liang, Zhao, Ting, Gu, Yusu, Dalton, Nancy D., Bang, Marie-Louise, Peterson, Kirk L., Chen, Ju
Published in Human molecular genetics (15.02.2009)
Published in Human molecular genetics (15.02.2009)
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A Defect in the Kv Channel-Interacting Protein 2 (KChIP2) Gene Leads to a Complete Loss of Ito and Confers Susceptibility to Ventricular Tachycardia
Kuo, Hai-Chien, Cheng, Ching-Feng, Clark, Robert B., Lin, Jim J.-C., Lin, Jenny L.-C., Hoshijima, Masahiko, Nguyêñ-Trân, Vân T.B., Gu, Yusu, Ikeda, Yasuhiro, Chu, Po-Hsien, Ross, John, Giles, Wayne R., Chien, Kenneth R.
Published in Cell (01.12.2001)
Published in Cell (01.12.2001)
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Chronic phospholamban inhibition prevents progressive cardiac dysfunction and pathological remodeling after infarction in rats
Iwanaga, Yoshitaka, Hoshijima, Masahiko, Gu, Yusu, Iwatate, Mitsuo, Dieterle, Thomas, Ikeda, Yasuhiro, Date, Moto-o, Chrast, Jacqueline, Matsuzaki, Masunori, Peterson, Kirk L, Chien, Kenneth R, Ross, Jr, John
Published in The Journal of clinical investigation (01.03.2004)
Published in The Journal of clinical investigation (01.03.2004)
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Journal Article
Impaired exercise capacity and skeletal muscle function in a mouse model of pulmonary inflammation
Tang, Kechun, Murano, George, Wagner, Harrieth, Nogueira, Leonardo, Wagner, Peter D, Tang, Alisa, Dalton, Nancy D, Gu, Yusu, Peterson, Kirk L, Breen, Ellen C
Published in Journal of applied physiology (1985) (01.05.2013)
Published in Journal of applied physiology (1985) (01.05.2013)
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Increased Echogenicity and Radiodense Foci on Echocardiogram and MicroCT in Murine Myocarditis
Peter, Angela K, Bradford, William H, Dalton, Nancy D, Gu, Yusu, Chao, Chieh-Ju, Peterson, Kirk L, Knowlton, Kirk U
Published in PloS one (03.08.2016)
Published in PloS one (03.08.2016)
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Chronic suppression of heart-failure progression by a pseudophosphorylated mutant of phospholamban via in vivo cardiac rAAV gene delivery
Chien, Kenneth R, Hoshijima, Masahiko, Ikeda, Yasuhiro, Iwanaga, Yoshitaka, Minamisawa, Susumu, Date, Moto-o, Gu, Yusu, Iwatate, Mitsuo, Li, Manxiang, Wang, Lili, Wilson, James M, Wang, Yibin, Ross, John
Published in Nature medicine (01.08.2002)
Published in Nature medicine (01.08.2002)
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Selective deletion of long but not short Cypher isoforms leads to late-onset dilated cardiomyopathy
HONGQIANG CHENG, MING ZHENG, YUSU GU, FREY, Norbert, PETERSON, Kirk L, EVANS, Sylvia M, KNOWLTON, Kirk U, SHEIKH, Farah, CHEW, Ju, PETER, Angela K, KIMURA, Kensuke, XIAODONG LI, KUNFU OUYANG, TAO SHEN, LI CUI, FRANK, Derk, DALTON, Nancy D
Published in Human molecular genetics (01.05.2011)
Published in Human molecular genetics (01.05.2011)
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α-E-catenin inactivation disrupts the cardiomyocyte adherens junction, resulting in cardiomyopathy and susceptibility to wall rupture
SHEIKH, Farah, YINGHONG CHEN, PETERSON, Kirk L, PERRIARD, Jean-Claude, JU CHEN, XINGQUN LIANG, HIRSCHY, Alain, STENBIT, Antine E, YUSU GU, DALTON, Nancy D, YAJIMA, Toshitaka, YINGCHUN LU, KNOWLTON, Kirk U
Published in Circulation (New York, N.Y.) (05.09.2006)
Published in Circulation (New York, N.Y.) (05.09.2006)
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Loss of a gp130 cardiac muscle cell survival pathway is a critical event in the onset of heart failure during biomechanical stress
Hirota, H, Chen, J, Betz, U A, Rajewsky, K, Gu, Y, Ross, Jr, J, Müller, W, Chien, K R
Published in Cell (16.04.1999)
Published in Cell (16.04.1999)
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Absence of SOCS3 in the Cardiomyocyte Increases Mortality in a gp130-Dependent Manner Accompanied by Contractile Dysfunction and Ventricular Arrhythmias
YAJIMA, Toshitaka, MUROFUSHI, Yoshiteru, DALTON, Nancy D, YAJIMA, Tomoko, YASUKAWA, Hideo, PETERSON, Kirk L, KNOWLTON, Kirk U, HANBING ZHOU, PARK, Stanley, HOUSMAN, Jonathan, ZHONG, Zhao-Hua, NAKAMURA, Michinari, MACHIDA, Mitsuyo, HWANG, Kyung-Kuk, YUSU GU
Published in Circulation (New York, N.Y.) (13.12.2011)
Published in Circulation (New York, N.Y.) (13.12.2011)
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Journal Article
Intermittent hypoxia and hypercapnia induce pulmonary artery atherosclerosis and ventricular dysfunction in low density lipoprotein receptor deficient mice
Douglas, Robert M, Bowden, Karen, Pattison, Jennifer, Peterson, Alexander B, Juliano, Joseph, Dalton, Nancy D, Gu, Yusu, Alvarez, Erika, Imamura, Toshihiro, Peterson, Kirk L, Witztum, Joseph L, Haddad, Gabriel G, Li, Andrew C
Published in Journal of applied physiology (1985) (01.12.2013)
Published in Journal of applied physiology (1985) (01.12.2013)
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A Cardiac Myocyte Vascular Endothelial Growth Factor Paracrine Pathway Is Required to Maintain Cardiac Function
Giordano, Frank J., Gerber, Hans-Peter, Williams, Simon-Peter, VanBruggen, Nicholas, Bunting, Stuart, Ruiz-Lozano, Pilar, Gu, Yusu, Nath, Anjali K., Huang, Yan, Hickey, Reed, Dalton, Nancy, Peterson, Kirk L., Ross, John, Chien, Kenneth R., Ferrara, Napoleone
Published in Proceedings of the National Academy of Sciences - PNAS (08.05.2001)
Published in Proceedings of the National Academy of Sciences - PNAS (08.05.2001)
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Chronic Phospholamban–Sarcoplasmic Reticulum Calcium ATPase Interaction Is the Critical Calcium Cycling Defect in Dilated Cardiomyopathy
Minamisawa, Susumu, Hoshijima, Masahiko, Chu, Guoxiang, Ward, Christopher A, Frank, Konrad, Gu, Yusu, Martone, Maryann E, Wang, Yibin, Ross, John, Kranias, Evangelia G, Giles, Wayne R, Chien, Kenneth R
Published in Cell (29.10.1999)
Published in Cell (29.10.1999)
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