The future is now: chimeric antigen receptors as new targeted therapies for childhood cancer
Lee, Daniel W, Barrett, David M, Mackall, Crystal, Orentas, Rimas, Grupp, Stephan A
Published in Clinical cancer research (15.05.2012)
Published in Clinical cancer research (15.05.2012)
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High-Affinity GD2-Specific CAR T Cells Induce Fatal Encephalitis in a Preclinical Neuroblastoma Model
Richman, Sarah A, Nunez-Cruz, Selene, Moghimi, Babak, Li, Lucy Z, Gershenson, Zachary T, Mourelatos, Zissimos, Barrett, David M, Grupp, Stephan A, Milone, Michael C
Published in Cancer immunology research (01.01.2018)
Published in Cancer immunology research (01.01.2018)
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Dissecting the Tumor-Immune Landscape in Chimeric Antigen Receptor T-cell Therapy: Key Challenges and Opportunities for a Systems Immunology Approach
Chen, Gregory M, Azzam, Andrew, Ding, Yang-Yang, Barrett, David M, Grupp, Stephan A, Tan, Kai
Published in Clinical cancer research (15.07.2020)
Published in Clinical cancer research (15.07.2020)
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Measuring IL-6 and sIL-6R in serum from patients treated with tocilizumab and/or siltuximab following CAR T cell therapy
Chen, Fang, Teachey, David T., Pequignot, Edward, Frey, Noelle, Porter, David, Maude, Shannon L., Grupp, Stephan A., June, Carl H., Melenhorst, Jan J., Lacey, Simon F.
Published in Journal of immunological methods (01.07.2016)
Published in Journal of immunological methods (01.07.2016)
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CD19-targeting CAR T cell immunotherapy outcomes correlate with genomic modification by vector integration
Nobles, Christopher L, Sherrill-Mix, Scott, Everett, John K, Reddy, Shantan, Fraietta, Joseph A, Porter, David L, Frey, Noelle, Gill, Saar I, Grupp, Stephan A, Maude, Shannon L, Siegel, Donald L, Levine, Bruce L, June, Carl H, Lacey, Simon F, Melenhorst, J Joseph, Bushman, Frederic D
Published in The Journal of clinical investigation (01.02.2020)
Published in The Journal of clinical investigation (01.02.2020)
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Targeting JAK1/2 and mTOR in murine xenograft models of Ph-like acute lymphoblastic leukemia
Maude, Shannon L., Tasian, Sarah K., Vincent, Tiffaney, Hall, Junior W., Sheen, Cecilia, Roberts, Kathryn G., Seif, Alix E., Barrett, David M., Chen, I-Ming, Collins, J. Racquel, Mullighan, Charles G., Hunger, Stephen P., Harvey, Richard C., Willman, Cheryl L., Fridman, Jordan S., Loh, Mignon L., Grupp, Stephan A., Teachey, David T.
Published in Blood (25.10.2012)
Published in Blood (25.10.2012)
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Real-world evidence of tisagenlecleucel for pediatric acute lymphoblastic leukemia and non-Hodgkin lymphoma
Pasquini, Marcelo C., Hu, Zhen-Huan, Curran, Kevin, Laetsch, Theodore, Locke, Frederick, Rouce, Rayne, Pulsipher, Michael A., Phillips, Christine L., Keating, Amy, Frigault, Matthew J., Salzberg, Dana, Jaglowski, Samantha, Sasine, Joshua P., Rosenthal, Joseph, Ghosh, Monalisa, Landsburg, Daniel, Margossian, Steven, Martin, Paul L., Kamdar, Manali K., Hematti, Peiman, Nikiforow, Sarah, Turtle, Cameron, Perales, Miguel-Angel, Steinert, Patricia, Horowitz, Mary M., Moskop, Amy, Pacaud, Lida, Yi, Lan, Chawla, Raghav, Bleickardt, Eric, Grupp, Stephan
Published in Blood advances (10.11.2020)
Published in Blood advances (10.11.2020)
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CAR-T cells: Early successes in blood cancer and challenges in solid tumors
Dana, Hassan, Chalbatani, Ghanbar Mahmoodi, Jalali, Seyed Amir, Mirzaei, Hamid Reza, Grupp, Stephan A., Suarez, Eloah Rabello, Rapôso, Catarina, Webster, Thomas J.
Published in Acta pharmaceutica Sinica. B (01.05.2021)
Published in Acta pharmaceutica Sinica. B (01.05.2021)
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Earlier defibrotide initiation post‐diagnosis of veno‐occlusive disease/sinusoidal obstruction syndrome improves Day +100 survival following haematopoietic stem cell transplantation
Richardson, Paul G., Smith, Angela R., Triplett, Brandon M., Kernan, Nancy A., Grupp, Stephan A., Antin, Joseph H., Lehmann, Leslie, Miloslavsky, Maja, Hume, Robin, Hannah, Alison L., Nejadnik, Bijan, Soiffer, Robert J.
Published in British journal of haematology (01.07.2017)
Published in British journal of haematology (01.07.2017)
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CAR T-cell therapy is effective for CD19-dim B-lymphoblastic leukemia but is impacted by prior blinatumomab therapy
Pillai, Vinodh, Muralidharan, Kavitha, Meng, Wenzhao, Bagashev, Asen, Oldridge, Derek A., Rosenthal, Jaclyn, Van Arnam, John, Melenhorst, Jos J., Mohan, Diwakar, DiNofia, Amanda M., Luo, Minjie, Cherian, Sindhu, Fromm, Jonathan R., Wertheim, Gerald, Thomas-Tikhonenko, Andrei, Paessler, Michele, June, Carl H., Luning Prak, Eline T., Bhoj, Vijay G., Grupp, Stephan A., Maude, Shannon L., Rheingold, Susan R.
Published in Blood advances (26.11.2019)
Published in Blood advances (26.11.2019)
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Treatment of advanced leukemia in mice with mRNA engineered T cells
Barrett, David M, Zhao, Yangbing, Liu, Xiaojun, Jiang, Shuguang, Carpenito, Carmine, Kalos, Michael, Carroll, Richard G, June, Carl H, Grupp, Stephan A
Published in Human gene therapy (01.12.2011)
Published in Human gene therapy (01.12.2011)
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Patient-reported quality of life after tisagenlecleucel infusion in children and young adults with relapsed or refractory B-cell acute lymphoblastic leukaemia: a global, single-arm, phase 2 trial
Laetsch, Theodore W, Myers, Gary Douglas, Baruchel, André, Dietz, Andrew C, Pulsipher, Michael A, Bittencourt, Henrique, Buechner, Jochen, De Moerloose, Barbara, Davis, Kara L, Nemecek, Eneida, Driscoll, Timothy, Mechinaud, Francoise, Boissel, Nicolas, Rives, Susana, Bader, Peter, Peters, Christina, Sabnis, Himalee S, Grupp, Stephan A, Yanik, Gregory A, Hiramatsu, Hidefumi, Stefanski, Heather E, Rasouliyan, Lawrence, Yi, Lan, Shah, Sweta, Zhang, Jie, Harris, Andrew C
Published in The lancet oncology (01.12.2019)
Published in The lancet oncology (01.12.2019)
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CD19 Alterations Emerging after CD19-Directed Immunotherapy Cause Retention of the Misfolded Protein in the Endoplasmic Reticulum
Bagashev, Asen, Sotillo, Elena, Tang, Chih-Hang Anthony, Black, Kathryn L., Perazzelli, Jessica, Seeholzer, Steven H., Argon, Yair, Barrett, David M., Grupp, Stephan A., Hu, Chih-Chi Andrew, Thomas-Tikhonenko, Andrei
Published in Molecular and cellular biology (01.11.2018)
Published in Molecular and cellular biology (01.11.2018)
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Biomarker correlates with response to NY-ESO-1 TCR T cells in patients with synovial sarcoma
Gyurdieva, Alexandra, Zajic, Stefan, Chang, Ya-Fang, Houseman, E. Andres, Zhong, Shan, Kim, Jaegil, Nathenson, Michael, Faitg, Thomas, Woessner, Mary, Turner, David C., Hasan, Aisha N., Glod, John, Kaplan, Rosandra N., D’Angelo, Sandra P., Araujo, Dejka M., Chow, Warren A., Druta, Mihaela, Demetri, George D., Van Tine, Brian A., Grupp, Stephan A., Fine, Gregg D., Eleftheriadou, Ioanna
Published in Nature communications (08.09.2022)
Published in Nature communications (08.09.2022)
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Reducing Ex Vivo Culture Improves the Antileukemic Activity of Chimeric Antigen Receptor (CAR) T Cells
Ghassemi, Saba, Nunez-Cruz, Selene, O'Connor, Roddy S, Fraietta, Joseph A, Patel, Prachi R, Scholler, John, Barrett, David M, Lundh, Stefan M, Davis, Megan M, Bedoya, Felipe, Zhang, Changfeng, Leferovich, John, Lacey, Simon F, Levine, Bruce L, Grupp, Stephan A, June, Carl H, Melenhorst, J Joseph, Milone, Michael C
Published in Cancer immunology research (01.09.2018)
Published in Cancer immunology research (01.09.2018)
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Repeated loss of target surface antigen after immunotherapy in primary mediastinal large B cell lymphoma
Yu, Hui, Sotillo, Elena, Harrington, Colleen, Wertheim, Gerald, Paessler, Michele, Maude, Shannon L., Rheingold, Susan R., Grupp, Stephan A., Thomas‐Tikhonenko, Andrei, Pillai, Vinodh
Published in American journal of hematology (01.01.2017)
Published in American journal of hematology (01.01.2017)
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Comprehensive Serum Proteome Profiling of Cytokine Release Syndrome and Immune Effector Cell-Associated Neurotoxicity Syndrome Patients with B-Cell ALL Receiving CAR T19
Diorio, Caroline, Shraim, Rawan, Myers, Regina, Behrens, Edward M, Canna, Scott, Bassiri, Hamid, Aplenc, Richard, Burudpakdee, Chakkapong, Chen, Fang, DiNofia, Amanda M, Gill, Saar, Gonzalez, Vanessa, Lambert, Michele P, Leahy, Allison Barz, Levine, Bruce L, Lindell, Robert B, Maude, Shannon L, Melenhorst, J Joseph, Newman, Haley, Perazzelli, Jessica, Seif, Alix E, Lacey, Simon F, June, Carl H, Barrett, David M, Grupp, Stephan A, Teachey, David T
Published in Clinical cancer research (01.09.2022)
Published in Clinical cancer research (01.09.2022)
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