Two Phase 3 Trials of Bapineuzumab in Mild-to-Moderate Alzheimer's Disease
Salloway, Stephen, Sperling, Reisa, Fox, Nick C, Blennow, Kaj, Klunk, William, Raskind, Murray, Sabbagh, Marwan, Honig, Lawrence S, Porsteinsson, Anton P, Ferris, Steven, Reichert, Marcel, Ketter, Nzeera, Nejadnik, Bijan, Guenzler, Volkmar, Miloslavsky, Maja, Wang, Daniel, Lu, Yuan, Lull, Julia, Tudor, Iulia Cristina, Liu, Enchi, Grundman, Michael, Yuen, Eric, Black, Ronald, Brashear, H. Robert
Published in The New England journal of medicine (23.01.2014)
Published in The New England journal of medicine (23.01.2014)
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Evaluation of smartphone‐based testing to generate exploratory outcome measures in a phase 1 Parkinson's disease clinical trial
Lipsmeier, Florian, Taylor, Kirsten I., Kilchenmann, Timothy, Wolf, Detlef, Scotland, Alf, Schjodt‐Eriksen, Jens, Cheng, Wei‐Yi, Fernandez‐Garcia, Ignacio, Siebourg‐Polster, Juliane, Jin, Liping, Soto, Jay, Verselis, Lynne, Boess, Frank, Koller, Martin, Grundman, Michael, Monsch, Andreas U., Postuma, Ronald B., Ghosh, Anirvan, Kremer, Thomas, Czech, Christian, Gossens, Christian, Lindemann, Michael
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Published in Movement disorders (01.08.2018)
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The clinical promise of biomarkers of synapse damage or loss in Alzheimer's disease
Colom-Cadena, Martí, Spires-Jones, Tara, Zetterberg, Henrik, Blennow, Kaj, Caggiano, Anthony, DeKosky, Steven T, Fillit, Howard, Harrison, John E, Schneider, Lon S, Scheltens, Phillip, de Haan, Willem, Grundman, Michael, van Dyck, Christopher H, Izzo, Nicholas J, Catalano, Susan M
Published in Alzheimer's research & therapy (02.03.2020)
Published in Alzheimer's research & therapy (02.03.2020)
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Amyloid-related imaging abnormalities in patients with Alzheimer's disease treated with bapineuzumab: a retrospective analysis
Sperling, Reisa, Dr, Salloway, Stephen, Prof, Brooks, David J, Prof, Tampieri, Donatella, MD, Barakos, Jerome, MD, Fox, Nick C, Prof, Raskind, Murray, Prof, Sabbagh, Marwan, MD, Honig, Lawrence S, MD, Porsteinsson, Anton P, Prof, Lieberburg, Ivan, MD, Arrighi, H Michael, PhD, Morris, Kristen A, MS, Lu, Yuan, MS, Liu, Enchi, PhD, Gregg, Keith M, PhD, Brashear, H Robert, MD, Kinney, Gene G, PhD, Black, Ronald, MD, Grundman, Michael, MD
Published in Lancet neurology (01.03.2012)
Published in Lancet neurology (01.03.2012)
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Vitamin E and Alzheimer disease : the basis for additional clinical trials
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Conference Proceeding
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Sigma-2 Receptors-From Basic Biology to Therapeutic Target: A Focus on Age-Related Degenerative Diseases
Lizama, Britney N, Kahle, Jennifer, Catalano, Susan M, Caggiano, Anthony O, Grundman, Michael, Hamby, Mary E
Published in International journal of molecular sciences (26.03.2023)
Published in International journal of molecular sciences (26.03.2023)
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Amyloid-related imaging abnormalities in amyloid-modifying therapeutic trials: Recommendations from the Alzheimer’s Association Research Roundtable Workgroup
Sperling, Reisa A, Jack, Clifford R, Black, Sandra E, Frosch, Matthew P, Greenberg, Steven M, Hyman, Bradley T, Scheltens, Philip, Carrillo, Maria C, Thies, William, Bednar, Martin M, Black, Ronald S, Brashear, H. Robert, Grundman, Michael, Siemers, Eric R, Feldman, Howard H, Schindler, Rachel J
Published in Alzheimer's & dementia (01.07.2011)
Published in Alzheimer's & dementia (01.07.2011)
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Preclinical and clinical biomarker studies of CT1812: A novel approach to Alzheimer's disease modification
Izzo, Nicholas J., Yuede, Carla M., LaBarbera, Kelsie M., Limegrover, Colleen S., Rehak, Courtney, Yurko, Raymond, Waybright, Lora, Look, Gary, Rishton, Gilbert, Safferstein, Hank, Hamby, Mary E., Williams, Claire, Sadlek, Kelsey, Edwards, Hannah M., Davis, Charles S., Grundman, Michael, Schneider, Lon S., DeKosky, Steven T., Chelsky, Daniel, Pike, Ian, Henstridge, Christopher, Blennow, Kaj, Zetterberg, Henrik, LeVine, Harry, Spires‐Jones, Tara L., Cirrito, John R., Catalano, Susan M.
Published in Alzheimer's & dementia (01.08.2021)
Published in Alzheimer's & dementia (01.08.2021)
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Rationale for use of the Clinical Dementia Rating Sum of Boxes as a primary outcome measure for Alzheimer’s disease clinical trials
Cedarbaum, Jesse M, Jaros, Mark, Hernandez, Chito, Coley, Nicola, Andrieu, Sandrine, Grundman, Michael, Vellas, Bruno
Published in Alzheimer's & dementia (01.02.2013)
Published in Alzheimer's & dementia (01.02.2013)
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A randomized, single ascending dose study of intravenous BIIB092 in healthy participants
Qureshi, Irfan A., Tirucherai, Giridhar, Ahlijanian, Michael K., Kolaitis, Gerry, Bechtold, Clifford, Grundman, Michael
Published in Alzheimer's & dementia : translational research & clinical interventions (2018)
Published in Alzheimer's & dementia : translational research & clinical interventions (2018)
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Vitamin E and Donepezil for the Treatment of Mild Cognitive Impairment
Petersen, Ronald C, Thomas, Ronald G, Grundman, Michael, Bennett, David, Doody, Rachelle, Ferris, Steven, Galasko, Douglas, Jin, Shelia, Kaye, Jeffrey, Levey, Allan, Pfeiffer, Eric, Sano, Mary, van Dyck, Christopher H, Thal, Leon J
Published in The New England journal of medicine (09.06.2005)
Published in The New England journal of medicine (09.06.2005)
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Long-term follow-up of patients immunized with AN1792: reduced functional decline in antibody responders
Vellas, Bruno, Black, R, Thal, Leon J, Fox, Nick C, Daniels, M, McLennan, G, Tompkins, C, Leibman, C, Pomfret, M, Grundman, Michael
Published in Current Alzheimer research (01.04.2009)
Published in Current Alzheimer research (01.04.2009)
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A phase 1 clinical trial of the sigma-2 receptor complex allosteric antagonist CT1812, a novel therapeutic candidate for Alzheimer's disease
Grundman, Michael, Morgan, Roger, Lickliter, Jason D., Schneider, Lon S., DeKosky, Steven, Izzo, Nicholas J., Guttendorf, Robert, Higgin, Michelle, Pribyl, Julie, Mozzoni, Kelsie, Safferstein, Hank, Catalano, Susan M.
Published in Alzheimer's & dementia : translational research & clinical interventions (2019)
Published in Alzheimer's & dementia : translational research & clinical interventions (2019)
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The ADAS-Cog revisited: Novel composite scales based on ADAS-Cog to improve efficiency in MCI and early AD trials
Raghavan, Nandini, Samtani, Mahesh N, Farnum, Michael, Yang, Eric, Novak, Gerald, Grundman, Michael, Narayan, Vaibhav, DiBernardo, Allitia
Published in Alzheimer's & dementia (01.02.2013)
Published in Alzheimer's & dementia (01.02.2013)
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Designing drug trials for Alzheimer’s disease: What we have learned from the release of the phase III antibody trials: A report from the EU/US/CTAD Task Force
Vellas, Bruno, Carrillo, Maria C, Sampaio, Cristina, Brashear, H. Robert, Siemers, Eric, Hampel, Harald, Schneider, Lon S, Weiner, Michael, Doody, Rachelle, Khachaturian, Zaven, Cedarbaum, Jesse, Grundman, Michael, Broich, Karl, Giacobini, Ezio, Dubois, Bruno, Sperling, Reisa, Wilcock, Gordon K, Fox, Nick, Scheltens, Philip, Touchon, Jacques, Hendrix, Suzanne, Andrieu, Sandrine, Aisen, Paul
Published in Alzheimer's & dementia (01.07.2013)
Published in Alzheimer's & dementia (01.07.2013)
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Conference Proceeding
Assessing cognition and function in Alzheimer's disease clinical trials: Do we have the right tools?
Snyder, Peter J, Kahle-Wrobleski, Kristin, Brannan, Stephen, Miller, David S, Schindler, Rachel J, DeSanti, Susan, Ryan, J. Michael, Morrison, Glenn, Grundman, Michael, Chandler, Julie, Caselli, Richard J, Isaac, Maria, Bain, Lisa, Carrillo, Maria C
Published in Alzheimer's & dementia (01.11.2014)
Published in Alzheimer's & dementia (01.11.2014)
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A pilot study to evaluate the effect of CT1812 treatment on synaptic density and other biomarkers in Alzheimer's disease
van Dyck, Christopher H, Mecca, Adam P, O'Dell, Ryan S, Bartlett, Hugh H, Diepenbrock, Nina G, Huang, Yiyun, Hamby, Mary E, Grundman, Michael, Catalano, Susan M, Caggiano, Anthony O, Carson, Richard E
Published in Alzheimer's research & therapy (25.01.2024)
Published in Alzheimer's research & therapy (25.01.2024)
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Effectiveness of Florbetapir PET Imaging in Changing Patient Management
Pontecorvo, Michael J., Siderowf, Andrew, Dubois, Bruno, Doraiswamy, P. Murali, Frisoni, Giovanni B., Grundman, Michael, Nobili, Flavio, Sadowsky, Carl H., Salloway, Stephen, Arora, Anupa K., Chevrette, Antoine, Deberdt, Walter, Dell'Agnello, Grazia, Flitter, Matthew, Galante, Nick, Lowrey, Mark J., Lu, Ming, McGeehan, Anne, Devous Sr, Michael D., Mintun, Mark A.
Published in Dementia and geriatric cognitive disorders (01.11.2017)
Published in Dementia and geriatric cognitive disorders (01.11.2017)
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A phase 1 open-label pilot study of low-dose interleukine-2 immunotherapy in patients with Alzheimer's disease
Faridar, Alireza, Eid, Abdulmunaim M, Thome, Aaron D, Zhao, Weihua, Beers, David R, Pascual, Maria B, Nakawah, Mohammad O, Roman, Gustavo C, Davis, Charles S, Grundman, Michael, Masdeu, Joseph C, Appel, Stanley H
Published in Translational neurodegeneration (16.11.2023)
Published in Translational neurodegeneration (16.11.2023)
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