Inhibition of arginase by CB-1158 blocks myeloid cell-mediated immune suppression in the tumor microenvironment
Steggerda, Susanne M, Bennett, Mark K, Chen, Jason, Emberley, Ethan, Huang, Tony, Janes, Julie R, Li, Weiqun, MacKinnon, Andrew L, Makkouk, Amani, Marguier, Gisele, Murray, Peter J, Neou, Silinda, Pan, Alison, Parlati, Francesco, Rodriguez, Mirna L M, Van de Velde, Lee-Ann, Wang, Tracy, Works, Melissa, Zhang, Jing, Zhang, Winter, Gross, Matthew I
Published in Journal for immunotherapy of cancer (19.12.2017)
Published in Journal for immunotherapy of cancer (19.12.2017)
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Journal Article
The glial modulatory drug AV411 attenuates mechanical allodynia in rat models of neuropathic pain
Ledeboer, Annemarie, Liu, Tongyao, Shumilla, Jennifer A., Mahoney, John H., Vijay, Sharmila, Gross, Matthew I., Vargas, Joseph A., Sultzbaugh, Lance, Claypool, Mark D., Sanftner, Laura M., Watkins, Linda R., Johnson, Kirk W.
Published in Neuron glia biology (01.11.2006)
Published in Neuron glia biology (01.11.2006)
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Journal Article
Ibudilast in healthy volunteers: safety, tolerability and pharmacokinetics with single and multiple doses
Rolan, Paul, Gibbons, Jacqueline A., He, Lin, Chang, Eppie, Jones, Drew, Gross, Matthew I., Davidson, Jennifer Bahr, Sanftner, Laura M., Johnson, Kirk W.
Published in British journal of clinical pharmacology (01.12.2008)
Published in British journal of clinical pharmacology (01.12.2008)
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Journal Article
DNA Binding Ligands with Improved in Vitro and in Vivo Potency against Drug-Resistant Staphylococcus aureus
Hu, Wenhao, Bürli, Roland W, Kaizerman, Jacob A, Johnson, Kirk W, Gross, Matthew I, Iwamoto, Mari, Jones, Peter, Lofland, Denene, Difuntorum, Stacey, Chen, Hsiu, Bozdogan, Bülent, Appelbaum, Peter C, Moser, Heinz E
Published in Journal of medicinal chemistry (26.08.2004)
Published in Journal of medicinal chemistry (26.08.2004)
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Journal Article
글루타미나제 억제제와 면역-종양학적 약제에 의한 병용 요법
MOLINEAUX SUSAN M, BROMLEY SUSAN D, BENNETT MARK K, PARLATI FRANCESCO, GROSS MATTHEW I
Year of Publication 04.06.2018
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Year of Publication 04.06.2018
Patent
DNA Binding Ligands Targeting Drug-Resistant Bacteria: Structure, Activity, and Pharmacology
Kaizerman, Jacob A, Gross, Matthew I, Ge, Yigong, White, Sarah, Hu, Wenhao, Duan, Jian-Xin, Baird, Eldon E, Johnson, Kirk W, Tanaka, Richard D, Moser, Heinz E, Bürli, Roland W
Published in Journal of medicinal chemistry (28.08.2003)
Published in Journal of medicinal chemistry (28.08.2003)
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Journal Article
아르기나제 활성을 억제시키기 위한 조성물 및 방법
PETERSEN LENE RAUNKJAER, STANTON TIMOTHY F, CHEN LIJING, WHITEHOUSE DARREN, LI JIM, PARLATI FRANCESCO, JAGDMANN GUNNAR E. JR, SJOGREN ERIC B, BILLEDEAU ROLAND J, GROSS MATTHEW I, VAN ZANDT MICHAEL
Year of Publication 22.10.2019
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Year of Publication 22.10.2019
Patent
TREATMENT OF CANCER WITH HETEROCYCLIC INHIBITORS OF GLUTAMINASE
STANTON TIMOTHY FRIEND, GOYAL BINDU, CHEN LIJING, LAIDIG GUY, BENNETT MARK K, BROMLEY SUSAN D, SJOGREN ERIC BRIAN, LI JIM, GROSS MATTHEW I
Year of Publication 10.08.2015
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Year of Publication 10.08.2015
Patent
Abstract 4134: Reversal of adenosine-mediated immune suppression by CB-708, an orally bioavailable and potent small molecule inhibitor of CD73
Lee, Clarissa C., Bhupathi, Deepthi, Billedeau, Roland J., Chen, Jason, Chen, Lijing, Emberley, Ethan D., Gross, Matthew I., Huang, Tony, Li, Weiqun, Ma, Yong, Mackinnon, Andrew L., Makkouk, Amani, Marguier, Gisele M., Neou, Silinda, Parlati, Francesco, Sotirovska, Natalija, Stanton, Timothy F., Steggerda, Susanne M., Zhang, Jing, Zhang, Winter, Li, Jim
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Journal Article
Abstract 1416: CB-839, a novel potent and selective glutaminase inhibitor, has broad antiproliferative activity in cell lines derived from both solid tumors and hematological malignancies
Parlati, Francesco, Demo, Susan D., Gross, Matthew I., Janes, Julie R., Lewis, Evan R., MacKinnon, Andy L., Rodriguez, Mirna L.M., Shwonek, Peter J., Wang, Taotao, Yang, Jinfu, Zhang, Dong, Zhao, Frances, Bennett, Mark K.
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
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Abstract 966: Novel pharmacodynamic assays to measure glutaminase inhibition following oral administration of CB-839
MacKinnon, Andy L., Bennett, Mark K., Gross, Matthew I., Janes, Julie R., Lewis, Evan R., Rodriguez, Mirna L.M., Shwonek, Peter J., Taotao, Wang, Yang, Jinfu, Zhao, Frances, Parlati, Francesco
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
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