Fah Knockout Animals as Models for Therapeutic Liver Repopulation
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Book Chapter
Journal Article
Proliferative polyploid cells give rise to tumors via ploidy reduction
Matsumoto, Tomonori, Wakefield, Leslie, Peters, Alexander, Peto, Myron, Spellman, Paul, Grompe, Markus
Published in Nature communications (28.01.2021)
Published in Nature communications (28.01.2021)
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Journal Article
Generation and Regeneration of Cells of the Liver and Pancreas
Zaret, Kenneth S, Grompe, Markus
Published in Science (American Association for the Advancement of Science) (05.12.2008)
Published in Science (American Association for the Advancement of Science) (05.12.2008)
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Journal Article
Clonal tracing of Sox9+ liver progenitors in mouse oval cell injury
Tarlow, Branden D., Finegold, Milton J., Grompe, Markus
Published in Hepatology (Baltimore, Md.) (01.07.2014)
Published in Hepatology (Baltimore, Md.) (01.07.2014)
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Journal Article
Directed differentiation of cholangiocytes from human pluripotent stem cells
Ogawa, Mina, Ogawa, Shinichiro, Bear, Christine E, Ahmadi, Saumel, Chin, Stephanie, Li, Bin, Grompe, Markus, Keller, Gordon, Kamath, Binita M, Ghanekar, Anand
Published in Nature biotechnology (01.08.2015)
Published in Nature biotechnology (01.08.2015)
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Journal Article
Selection and evaluation of clinically relevant AAV variants in a xenograft liver model
Lisowski, Leszek, Dane, Allison P., Chu, Kirk, Zhang, Yue, Cunningham, Sharon C., Wilson, Elizabeth M., Nygaard, Sean, Grompe, Markus, Alexander, Ian E., Kay, Mark A.
Published in Nature (London) (20.02.2014)
Published in Nature (London) (20.02.2014)
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Journal Article
Human islets contain four distinct subtypes of β cells
Dorrell, Craig, Schug, Jonathan, Canaday, Pamela S., Russ, Holger A., Tarlow, Branden D., Grompe, Maria T., Horton, Tamara, Hebrok, Matthias, Streeter, Philip R., Kaestner, Klaus H., Grompe, Markus
Published in Nature communications (11.07.2016)
Published in Nature communications (11.07.2016)
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Journal Article
Comprehensive human cell-type methylation atlas reveals origins of circulating cell-free DNA in health and disease
Moss, Joshua, Magenheim, Judith, Neiman, Daniel, Zemmour, Hai, Loyfer, Netanel, Korach, Amit, Samet, Yaacov, Maoz, Myriam, Druid, Henrik, Arner, Peter, Fu, Keng-Yeh, Kiss, Endre, Spalding, Kirsty L., Landesberg, Giora, Zick, Aviad, Grinshpun, Albert, Shapiro, A. M. James, Grompe, Markus, Wittenberg, Avigail Dreazan, Glaser, Benjamin, Shemer, Ruth, Kaplan, Tommy, Dor, Yuval
Published in Nature communications (29.11.2018)
Published in Nature communications (29.11.2018)
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Journal Article
In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration
Huch, Meritxell, Dorrell, Craig, Boj, Sylvia F., van Es, Johan H., Li, Vivian S. W., van de Wetering, Marc, Sato, Toshiro, Hamer, Karien, Sasaki, Nobuo, Finegold, Milton J., Haft, Annelise, Vries, Robert G., Grompe, Markus, Clevers, Hans
Published in Nature (London) (14.02.2013)
Published in Nature (London) (14.02.2013)
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Journal Article
Liver Injury Increases the Incidence of HCC following AAV Gene Therapy in Mice
Dalwadi, Dhwanil A., Torrens, Laura, Abril-Fornaguera, Jordi, Pinyol, Roser, Willoughby, Catherine, Posey, Jeffrey, Llovet, Josep M., Lanciault, Christian, Russell, David W., Grompe, Markus, Naugler, Willscott E.
Published in Molecular therapy (03.02.2021)
Published in Molecular therapy (03.02.2021)
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Journal Article
Diagnosis and treatment of tyrosinemia type I: a US and Canadian consensus group review and recommendations
Chinsky, Jeffrey M, Singh, Rani, Ficicioglu, Can, van Karnebeek, Clara D M, Grompe, Markus, Mitchell, Grant, Waisbren, Susan E, Gucsavas-Calikoglu, Muge, Wasserstein, Melissa P, Coakley, Katie, Scott, C Ronald
Published in Genetics in medicine (01.12.2017)
Published in Genetics in medicine (01.12.2017)
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Journal Article
Generation of functional ciliated cholangiocytes from human pluripotent stem cells
Ogawa, Mina, Jiang, Jia-Xin, Xia, Sunny, Yang, Donghe, Ding, Avrilynn, Laselva, Onofrio, Hernandez, Marcela, Cui, Changyi, Higuchi, Yuichiro, Suemizu, Hiroshi, Dorrell, Craig, Grompe, Markus, Bear, Christine E., Ogawa, Shinichiro
Published in Nature communications (11.11.2021)
Published in Nature communications (11.11.2021)
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Journal Article
Identification of tissue-specific cell death using methylation patterns of circulating DNA
Lehmann-Werman, Roni, Neiman, Daniel, Zemmour, Hai, Moss, Joshua, Magenheim, Judith, Vaknin-Dembinsky, Adi, Rubertsson, Sten, Nellgård, Bengt, Blennow, Kaj, Zetterberg, Henrik, Spalding, Kirsty, Haller, Michael J., Wasserfall, Clive H., Schatz, Desmond A., Greenbaum, Carla J., Dorrell, Craig, Grompe, Markus, Zick, Aviad, Hubert, Ayala, Maoz, Myriam, Fendrich, Volker, Bartsch, Detlef K., Golan, Talia, Sasson, Shmuel A. Ben, Zamir, Gideon, Razin, Aharon, Cedar, Howard, Shapiro, A. M. James, Glaser, Benjamin, Shemer, Ruth, Dor, Yuval
Published in Proceedings of the National Academy of Sciences - PNAS (29.03.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (29.03.2016)
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Journal Article
Self-cleaving guide RNAs enable pharmacological selection of precise gene editing events in vivo
Tiyaboonchai, Amita, Vonada, Anne, Posey, Jeffrey, Pelz, Carl, Wakefield, Leslie, Grompe, Markus
Published in Nature communications (30.11.2022)
Published in Nature communications (30.11.2022)
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Journal Article
The ploidy conveyor of mature hepatocytes as a source of genetic variation
Duncan, Andrew W, Taylor, Matthew H, Hickey, Raymond D, Hanlon Newell, Amy E, Lenzi, Michelle L, Olson, Susan B, Finegold, Milton J, Grompe, Markus
Published in Nature (London) (07.10.2010)
Published in Nature (London) (07.10.2010)
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Journal Article
Glycoprotein 2 is a specific cell surface marker of human pancreatic progenitors
Cogger, Kathryn F., Sinha, Ankit, Sarangi, Farida, McGaugh, Emily C., Saunders, Diane, Dorrell, Craig, Mejia-Guerrero, Salvador, Aghazadeh, Yasaman, Rourke, Jillian L., Screaton, Robert A., Grompe, Markus, Streeter, Philip R., Powers, Alvin C., Brissova, Marcela, Kislinger, Thomas, Nostro, M. Cristina
Published in Nature communications (24.08.2017)
Published in Nature communications (24.08.2017)
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Journal Article
A universal system to select gene-modified hepatocytes in vivo
Nygaard, Sean, Barzel, Adi, Haft, Annelise, Major, Angela, Finegold, Milton, Kay, Mark A, Grompe, Markus
Published in Science translational medicine (08.06.2016)
Published in Science translational medicine (08.06.2016)
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Journal Article
Robust expansion of human hepatocytes in Fah −/− / Rag2 −/− / Il2rg −/− mice
Grompe, Markus, Azuma, Hisaya, Paulk, Nicole, Ranade, Aarati, Dorrell, Craig, Al-Dhalimy, Muhsen, Ellis, Ewa, Strom, Stephen, Kay, Mark A, Finegold, Milton
Published in Nature biotechnology (01.08.2007)
Published in Nature biotechnology (01.08.2007)
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Journal Article
Metformin improves defective hematopoiesis and delays tumor formation in Fanconi anemia mice
Zhang, Qing-Shuo, Tang, Weiliang, Deater, Matthew, Phan, Ngoc, Marcogliese, Andrea N., Li, Hui, Al-Dhalimy, Muhsen, Major, Angela, Olson, Susan, Monnat, Raymond J., Grompe, Markus
Published in Blood (15.12.2016)
Published in Blood (15.12.2016)
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