Transforming growth factor-β superfamily ligand trap ACE-536 corrects anemia by promoting late-stage erythropoiesis
Suragani, Rajasekhar N V S, Cadena, Samuel M, Cawley, Sharon M, Sako, Dianne, Mitchell, Dianne, Li, Robert, Davies, Monique V, Alexander, Mark J, Devine, Matthew, Loveday, Kenneth S, Underwood, Kathryn W, Grinberg, Asya V, Quisel, John D, Chopra, Rajesh, Pearsall, R Scott, Seehra, Jasbir, Kumar, Ravindra
Published in Nature medicine (01.04.2014)
Published in Nature medicine (01.04.2014)
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ActRIIB:ALK4-Fc alleviates muscle dysfunction and comorbidities in murine models of neuromuscular disorders
Li, Jia, Fredericks, Maureen, Cannell, Marishka, Wang, Kathryn, Sako, Dianne, Maguire, Michelle C, Grenha, Rosa, Liharska, Katia, Krishnan, Lavanya, Bloom, Troy, Belcheva, Elitza P, Martinez, Pedro A, Castonguay, Roselyne, Keates, Sarah, Alexander, Mark J, Choi, Hyunwoo, Grinberg, Asya V, Pearsall, R Scott, Oh, Paul, Kumar, Ravindra, Suragani, Rajasekhar Nvs
Published in The Journal of clinical investigation (15.02.2021)
Published in The Journal of clinical investigation (15.02.2021)
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Journal Article
Specificity and Structure of a High Affinity Activin Receptor-like Kinase 1 (ALK1) Signaling Complex
Townson, Sharon A., Martinez-Hackert, Erik, Greppi, Chloe, Lowden, Patricia, Sako, Dianne, Liu, June, Ucran, Jeffrey A., Liharska, Katia, Underwood, Kathryn W., Seehra, Jasbir, Kumar, Ravindra, Grinberg, Asya V.
Published in The Journal of biological chemistry (10.08.2012)
Published in The Journal of biological chemistry (10.08.2012)
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Journal Article
Soluble Endoglin Specifically Binds Bone Morphogenetic Proteins 9 and 10 via Its Orphan Domain, Inhibits Blood Vessel Formation, and Suppresses Tumor Growth
Castonguay, Roselyne, Werner, Eric D., Matthews, Robert G., Presman, Eleonora, Mulivor, Aaron W., Solban, Nicolas, Sako, Dianne, Pearsall, R. Scott, Underwood, Kathryn W., Seehra, Jasbir, Kumar, Ravindra, Grinberg, Asya V.
Published in The Journal of biological chemistry (26.08.2011)
Published in The Journal of biological chemistry (26.08.2011)
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Journal Article
Modified activin receptor IIB ligand trap mitigates ineffective erythropoiesis and disease complications in murine β-thalassemia
Suragani, Rajasekhar N.V.S., Cawley, Sharon M., Li, Robert, Wallner, Samantha, Alexander, Mark J., Mulivor, Aaron W., Gardenghi, Sara, Rivella, Stefano, Grinberg, Asya V., Pearsall, R. Scott, Kumar, Ravindra
Published in Blood (19.06.2014)
Published in Blood (19.06.2014)
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Journal Article
Functionally diverse heteromeric traps for ligands of the transforming growth factor-β superfamily
Kumar, Ravindra, Grinberg, Asya V., Li, Huiming, Kuo, Tzu-Hsing, Sako, Dianne, Krishnan, Lavanya, Liharska, Katia, Li, Jia, Grenha, Rosa, Maguire, Michelle C., Briscoe, Steven D., Pearsall, R. Scott, Herrin, Brantley R., Suragani, Rajasekhar N. V. S., Castonguay, Roselyne
Published in Scientific reports (15.09.2021)
Published in Scientific reports (15.09.2021)
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Journal Article
A Novel Therapeutic Approach to Treating Obesity through Modulation of TGFβ Signaling
Koncarevic, Alan, Kajimura, Shingo, Cornwall-Brady, Milton, Andreucci, Amy, Pullen, Abigail, Sako, Dianne, Kumar, Ravindra, Grinberg, Asya V, Liharska, Katia, Ucran, Jeffrey A, Howard, Elizabeth, Spiegelman, Bruce M, Seehra, Jasbir, Lachey, Jennifer
Published in Endocrinology (Philadelphia) (01.07.2012)
Published in Endocrinology (Philadelphia) (01.07.2012)
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Journal Article
ALK1-Fc inhibits multiple mediators of angiogenesis and suppresses tumor growth
Mitchell, Dianne, Pobre, Eileen G, Mulivor, Aaron W, Grinberg, Asya V, Castonguay, Roselyne, Monnell, Travis E, Solban, Nicolas, Ucran, Jeffrey A, Pearsall, R Scott, Underwood, Kathryn W, Seehra, Jasbir, Kumar, Ravindra
Published in Molecular cancer therapeutics (01.02.2010)
Published in Molecular cancer therapeutics (01.02.2010)
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Journal Article
Characterization of the Ligand Binding Functionality of the Extracellular Domain of Activin Receptor Type IIB
Sako, Dianne, Grinberg, Asya V., Liu, June, Davies, Monique V., Castonguay, Roselyne, Maniatis, Silas, Andreucci, Amy J., Pobre, Eileen G., Tomkinson, Kathleen N., Monnell, Travis E., Ucran, Jeffrey A., Martinez-Hackert, Erik, Pearsall, R. Scott, Underwood, Kathryn W., Seehra, Jasbir, Kumar, Ravindra
Published in The Journal of biological chemistry (02.07.2010)
Published in The Journal of biological chemistry (02.07.2010)
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Journal Article
A Soluble Activin Type IIA Receptor Induces Bone Formation and Improves Skeletal Integrity
Pearsall, R. Scott, Canalis, Ernesto, Cornwall-Brady, Milton, Underwood, Kathryn W., Haigis, Brendan, Ucran, Jeffrey, Kumar, Ravindra, Pobre, Eileen, Grinberg, Asya, Werner, Eric D., Glatt, Vaida, Stadmeyer, Lisa, Smith, Deanna, Seehra, Jasbir, Bouxsein, Mary L.
Published in Proceedings of the National Academy of Sciences - PNAS (13.05.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (13.05.2008)
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A Soluble Activin Receptor Type IIB Prevents the Effects of Androgen Deprivation on Body Composition and Bone Health
Koncarevic, Alan, Cornwall-Brady, Milton, Pullen, Abigail, Davies, Monique, Sako, Dianne, Liu, June, Kumar, Ravindra, Tomkinson, Kathleen, Baker, Theresa, Umiker, Ben, Monnell, Travis, Grinberg, Asya V, Liharska, Katia, Underwood, Kathryn W, Ucran, Jeffrey A, Howard, Elizabeth, Barberio, Joseph, Spaits, Matthew, Pearsall, Scott, Seehra, Jasbir, Lachey, Jennifer
Published in Endocrinology (Philadelphia) (01.09.2010)
Published in Endocrinology (Philadelphia) (01.09.2010)
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Journal Article
Structures of activin ligand traps using natural sets of type I and type II TGFβ receptors
Goebel, Erich J., Kattamuri, Chandramohan, Gipson, Gregory R., Krishnan, Lavanya, Chavez, Moises, Czepnik, Magdalena, Maguire, Michelle C., Grenha, Rosa, Håkansson, Maria, Logan, Derek T., Grinberg, Asya V., Sako, Dianne, Castonguay, Roselyne, Kumar, Ravindra, Thompson, Thomas B.
Published in iScience (21.01.2022)
Published in iScience (21.01.2022)
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Journal Article
Visualization of Myc/Max/Mad Family Dimers and the Competition for Dimerization in Living Cells
Grinberg, Asya V., Hu, Chang-Deng, Kerppola, Tom K.
Published in Molecular and Cellular Biology (01.05.2004)
Published in Molecular and Cellular Biology (01.05.2004)
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Journal Article
soluble bone morphogenetic protein type IA receptor increases bone mass and bone strength
Baud’huin, Marc, Solban, Nicolas, Cornwall-Brady, Milton, Sako, Dianne, Kawamoto, Yoshimi, Liharska, Katia, Lath, Darren, Bouxsein, Mary L, Underwood, Kathryn W, Ucran, Jeffrey, Kumar, Ravindra, Pobre, Eileen, Grinberg, Asya, Seehra, Jasbir, Canalis, Ernesto, Pearsall, R. Scott, Croucher, Peter I
Published in Proceedings of the National Academy of Sciences - PNAS (24.07.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (24.07.2012)
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