The dynamic plasticity of insulin production in β-cells
Boland, Brandon B, Rhodes, Christopher J, Grimsby, Joseph S
Published in Molecular metabolism (Germany) (01.09.2017)
Published in Molecular metabolism (Germany) (01.09.2017)
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Differences in levels of phosphatidylinositols in healthy and stable Coronary Artery Disease subjects revealed by HILIC-MRM method with SERRF normalization
Huang, Yue, Mu, Ruipeng, Wen, David, Grimsby, Joseph S, Liang, Meina, Rosenbaum, Anton I
Published in PloS one (04.06.2021)
Published in PloS one (04.06.2021)
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Characterization of Signaling Pathways Associated with Pancreatic β-cell Adaptive Flexibility in Compensation of Obesity-linked Diabetes in db/db Mice
Kang, Taewook, Boland, Brandon B., Jensen, Pia, Alarcon, Cristina, Nawrocki, Arkadiusz, Grimsby, Joseph S., Rhodes, Christopher J., Larsen, Martin R.
Published in Molecular & cellular proteomics (01.06.2020)
Published in Molecular & cellular proteomics (01.06.2020)
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Proteomic Analysis of Restored Insulin Production and Trafficking in Obese Diabetic Mouse Pancreatic Islets Following Euglycemia
Kang, Taewook, Boland, Brandon B, Alarcon, Cristina, Grimsby, Joseph S, Rhodes, Christopher J, Larsen, Martin R
Published in Journal of proteome research (06.09.2019)
Published in Journal of proteome research (06.09.2019)
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The prevalence of low muscle mass associated with obesity in the USA
Murdock, Dana J, Wu, Ning, Grimsby, Joseph S, Calle, Roberto A, Donahue, Stephen, Glass, David J, Sleeman, Mark W, Sanchez, Robert J
Published in Skeletal muscle (21.12.2022)
Published in Skeletal muscle (21.12.2022)
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Pancreatic β-Cell Rest Replenishes Insulin Secretory Capacity and Attenuates Diabetes in an Extreme Model of Obese Type 2 Diabetes
Boland, Brandon B, Brown, Jr, Charles, Boland, Michelle L, Cann, Jennifer, Sulikowski, Michal, Hansen, Gitte, Grønlund, Rikke V, King, Wanda, Rondinone, Cristina, Trevaskis, James, Rhodes, Christopher J, Grimsby, Joseph S
Published in Diabetes (New York, N.Y.) (01.01.2019)
Published in Diabetes (New York, N.Y.) (01.01.2019)
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1200-P: The Prevalence of Obesity-Associated Loss of Lean Muscle Mass
MURDOCK, DANA J., WU, NING, GLASS, DAVID J., GRIMSBY, JOSEPH S., CALLE, ROBERTO A., DONAHUE, STEPHEN, SLEEMAN, MARK, SANCHEZ, ROBERT J.
Published in Diabetes (New York, N.Y.) (01.06.2022)
Published in Diabetes (New York, N.Y.) (01.06.2022)
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Resolution of NASH and hepatic fibrosis by the GLP-1R/GcgR dual-agonist Cotadutide via modulating mitochondrial function and lipogenesis
Boland, Michelle L, Laker, Rhianna C, Mather, Karly, Nawrocki, Arkadiusz, Oldham, Stephanie, Boland, Brandon B, Lewis, Hilary, Conway, James, Naylor, Jacqueline, Guionaud, Silvia, Feigh, Michael, Veidal, Sanne S, Lantier, Louise, McGuinness, Owen P, Grimsby, Joseph, Rondinone, Cristina M, Jermutus, Lutz, Larsen, Martin R, Trevaskis, James L, Rhodes, Christopher J
Published in Nature metabolism (01.05.2020)
Published in Nature metabolism (01.05.2020)
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Development of an orally delivered GLP-1 receptor agonist through peptide engineering and drug delivery to treat chronic disease
Pechenov, Sergei, Revell, Jefferson, Will, Sarah, Naylor, Jacqueline, Tyagi, Puneet, Patel, Chandresh, Liang, Lihuan, Tseng, Leo, Huang, Yue, Rosenbaum, Anton I, Balic, Kemal, Konkar, Anish, Grimsby, Joseph, Subramony, J Anand
Published in Scientific reports (18.11.2021)
Published in Scientific reports (18.11.2021)
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Journal Article
Pancreatic Beta Cells in Very Old Mice Retain Capacity for Compensatory Proliferation
Stolovich-Rain, Miri, Hija, Ayat, Grimsby, Joseph, Glaser, Benjamin, Dor, Yuval
Published in The Journal of biological chemistry (10.08.2012)
Published in The Journal of biological chemistry (10.08.2012)
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Journal Article
A novel glucagon‐like peptide 1/glucagon receptor dual agonist improves steatohepatitis and liver regeneration in mice
Valdecantos, M. Pilar, Pardo, Virginia, Ruiz, Laura, Castro‐Sánchez, Luis, Lanzón, Borja, Fernández‐Millán, Elisa, García‐Monzón, Carmelo, Arroba, Ana I., González‐Rodríguez, Águeda, Escrivá, Fernando, Álvarez, Carmen, Rupérez, Francisco J., Barbas, Coral, Konkar, Anish, Naylor, Jacqui, Hornigold, David, Santos, Ana Dos, Bednarek, Maria, Grimsby, Joseph, Rondinone, Cristina M., Valverde, Ángela M.
Published in Hepatology (Baltimore, Md.) (01.03.2017)
Published in Hepatology (Baltimore, Md.) (01.03.2017)
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Journal Article
LOX-1: A potential driver of cardiovascular risk in SLE patients
Sagar, Divya, Gaddipati, Ranjitha, Ongstad, Emily L, Bhagroo, Nicholas, An, Ling-Ling, Wang, Jingya, Belkhodja, Mehdi, Rahman, Saifur, Manna, Zerai, Davis, Michael A, Hasni, Sarfaraz, Siegel, Richard, Sanjuan, Miguel, Grimsby, Joseph, Kolbeck, Roland, Karathanasis, Sotirios, Sims, Gary P, Gupta, Ruchi
Published in PloS one (17.03.2020)
Published in PloS one (17.03.2020)
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High-throughput mediation analysis of human proteome and metabolome identifies mediators of post-bariatric surgical diabetes control
Dreyfuss, Jonathan M, Yuchi, Yixing, Dong, Xuehong, Efthymiou, Vissarion, Pan, Hui, Simonson, Donald C, Vernon, Ashley, Halperin, Florencia, Aryal, Pratik, Konkar, Anish, Sebastian, Yinong, Higgs, Brandon W, Grimsby, Joseph, Rondinone, Cristina M, Kasif, Simon, Kahn, Barbara B, Foster, Kathleen, Seeley, Randy, Goldfine, Allison, Djordjilović, Vera, Patti, Mary Elizabeth
Published in Nature communications (29.11.2021)
Published in Nature communications (29.11.2021)
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Blocking endothelial lipase with monoclonal antibody MEDI5884 durably increases high density lipoprotein in nonhuman primates and in a phase 1 trial
Le Lay, John E, Du, Qun, Mehta, Minal B, Bhagroo, Nicholas, Hummer, B Timothy, Falloon, Judith, Carlson, Glenn, Rosenbaum, Anton I, Jin, ChaoYu, Kimko, Holly, Tsai, Lan-Feng, Novick, Steven, Cook, Bill, Han, David, Han, Chang Yeop, Vaisar, Tomas, Chait, Alan, Karathanasis, Sotirios K, Rhodes, Christopher J, Hirshberg, Boaz, Damschroder, Melissa M, Hsia, Judith, Grimsby, Joseph S
Published in Science translational medicine (21.04.2021)
Published in Science translational medicine (21.04.2021)
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The Network of Glucokinase-Expressing Cells in Glucose Homeostasis and the Potential of Glucokinase Activators for Diabetes Therapy
Matschinsky, Franz M, Magnuson, Mark A, Zelent, Dorothy, Jetton, Tom L, Doliba, Nicolai, Han, Yi, Taub, Rebecca, Grimsby, Joseph
Published in Diabetes (New York, N.Y.) (01.01.2006)
Published in Diabetes (New York, N.Y.) (01.01.2006)
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Journal Article
Discovery of PiragliatinFirst Glucokinase Activator Studied in Type 2 Diabetic Patients
Sarabu, Ramakanth, Bizzarro, Fred T, Corbett, Wendy L, Dvorozniak, Mark T, Geng, Wanping, Grippo, Joseph F, Haynes, Nancy-Ellen, Hutchings, Stanley, Garofalo, Lisa, Guertin, Kevin R, Hilliard, Darryl W, Kabat, Marek, Kester, Robert F, Ka, Wang, Liang, Zhenmin, Mahaney, Paige E, Marcus, Linda, Matschinsky, Franz M, Moore, David, Racha, Jagdish, Radinov, Roumen, Ren, Yi, Qi, Lida, Pignatello, Michael, Spence, Cheryl L, Steele, Thomas, Tengi, John, Grimsby, Joseph
Published in Journal of medicinal chemistry (23.08.2012)
Published in Journal of medicinal chemistry (23.08.2012)
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Journal Article
Extremes of Clinical and Enzymatic Phenotypes in Children With Hyperinsulinism Caused by Glucokinase Activating Mutations
SAYED, Samir, LANGDON, David R, STANLEY, Charles A, ODILI, Stella, PAN CHEN, BUETTGER, Carol, SCHIFFMAN, Alisa B, SUCHI, Mariko, TAUB, Rebecca, GRIMSBY, Joseph, MATSCHINSKY, Franz M
Published in Diabetes (New York, N.Y.) (01.06.2009)
Published in Diabetes (New York, N.Y.) (01.06.2009)
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Glucokinase activation repairs defective bioenergetics of islets of Langerhans isolated from type 2 diabetics
Doliba, Nicolai M, Qin, Wei, Najafi, Habiba, Liu, Chengyang, Buettger, Carol W, Sotiris, Johanna, Collins, Heather W, Li, Changhong, Stanley, Charles A, Wilson, David F, Grimsby, Joseph, Sarabu, Ramakanth, Naji, Ali, Matschinsky, Franz M
Published in American journal of physiology: endocrinology and metabolism (01.01.2012)
Published in American journal of physiology: endocrinology and metabolism (01.01.2012)
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