Thbs1 induces lethal cardiac atrophy through PERK-ATF4 regulated autophagy
Vanhoutte, Davy, Schips, Tobias G, Vo, Alexander, Grimes, Kelly M, Baldwin, Tanya A, Brody, Matthew J, Accornero, Federica, Sargent, Michelle A, Molkentin, Jeffery D
Published in Nature communications (24.06.2021)
Published in Nature communications (24.06.2021)
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Journal Article
MCUb Induction Protects the Heart From Postischemic Remodeling
Huo, Jiuzhou, Lu, Shan, Kwong, Jennifer Q, Bround, Michael J, Grimes, Kelly M, Sargent, Michelle A, Brown, Milton E, Davis, Michael E, Bers, Donald M, Molkentin, Jeffery D
Published in Circulation research (17.07.2020)
Published in Circulation research (17.07.2020)
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Journal Article
TGFBI functions similar to periostin but is uniquely dispensable during cardiac injury
Schwanekamp, Jennifer A, Lorts, Angela, Sargent, Michelle A, York, Allen J, Grimes, Kelly M, Fischesser, Demetria M, Gokey, Jason J, Whitsett, Jeffrey A, Conway, Simon J, Molkentin, Jeffery D
Published in PloS one (27.07.2017)
Published in PloS one (27.07.2017)
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Journal Article
Supporting the heart: Functions of the cardiomyocyte's non-sarcomeric cytoskeleton
Grimes, Kelly M., Prasad, Vikram, McNamara, James W.
Published in Journal of molecular and cellular cardiology (01.06.2019)
Published in Journal of molecular and cellular cardiology (01.06.2019)
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Journal Article
Probing Pedomorphy and Prolonged Lifespan in Naked Mole-Rats and Dwarf Mice
Buffenstein, Rochelle, Lewis, Kaitlyn N, Gibney, Patrick A, Narayan, Vikram, Grimes, Kelly M, Smith, Megan, Lin, Tzuhua D, Brown-Borg, Holly M
Published in Physiology (Bethesda, Md.) (01.03.2020)
Published in Physiology (Bethesda, Md.) (01.03.2020)
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Journal Article
A human FLII gene variant alters sarcomeric actin thin filament length and predisposes to cardiomyopathy
Kuwabara, Yasuhide, York, Allen J, Lin, Suh-Chin, Sargent, Michelle A, Grimes, Kelly M, Pirruccello, James P, Molkentin, Jeffery D
Published in Proceedings of the National Academy of Sciences - PNAS (09.05.2023)
Published in Proceedings of the National Academy of Sciences - PNAS (09.05.2023)
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Journal Article
MEK1-ERK1/2 signaling regulates the cardiomyocyte non-sarcomeric actin cytoskeletal network
Grimes, Kelly M, Maillet, Marjorie, Swoboda, Casey O, Bowers, Stephanie L K, Millay, Doug P, Molkentin, Jeffery D
Published in American journal of physiology. Heart and circulatory physiology (01.01.2024)
Published in American journal of physiology. Heart and circulatory physiology (01.01.2024)
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Journal Article
MCUb is an inducible regulator of calcium-dependent mitochondrial metabolism and substrate utilization in muscle
Huo, Jiuzhou, Prasad, Vikram, Grimes, Kelly M., Vanhoutte, Davy, Blair, N. Scott, Lin, Suh-Chin, Bround, Michael J., Bers, Donald M., Molkentin, Jeffery D.
Published in Cell reports (Cambridge) (28.11.2023)
Published in Cell reports (Cambridge) (28.11.2023)
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Journal Article
Basic Cardiovascular Sciences Scientific Sessions 2018: Innovating in Cardiovascular Research
McNamara, James W, Grimes, Kelly M, Sadayappan, Sakthivel
Published in Circulation research (12.10.2018)
Published in Circulation research (12.10.2018)
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Journal Article
And the beat goes on: maintained cardiovascular function during aging in the longest-lived rodent, the naked mole-rat
Grimes, Kelly M, Reddy, Anilkumar K, Lindsey, Merry L, Buffenstein, Rochelle
Published in American journal of physiology. Heart and circulatory physiology (01.08.2014)
Published in American journal of physiology. Heart and circulatory physiology (01.08.2014)
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Journal Article
Overlapping and differential functions of ATF6α versus ATF6β in the mouse heart
Correll, Robert N, Grimes, Kelly M, Prasad, Vikram, Lynch, Jeffrey M, Khalil, Hadi, Molkentin, Jeffery D
Published in Scientific reports (14.02.2019)
Published in Scientific reports (14.02.2019)
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Journal Article
Cardiac function of the naked mole-rat: ecophysiological responses to working underground
Grimes, Kelly M, Voorhees, Andrew, Chiao, Ying Ann, Han, Hai-Chao, Lindsey, Merry L, Buffenstein, Rochelle
Published in American journal of physiology. Heart and circulatory physiology (01.03.2014)
Published in American journal of physiology. Heart and circulatory physiology (01.03.2014)
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Journal Article
ERK1/2 signaling induces skeletal muscle slow fiber-type switching and reduces muscular dystrophy disease severity
Boyer, Justin G, Prasad, Vikram, Song, Taejeong, Lee, Donghoon, Fu, Xing, Grimes, Kelly M, Sargent, Michelle A, Sadayappan, Sakthivel, Molkentin, Jeffery D
Published in JCI insight (16.05.2019)
Published in JCI insight (16.05.2019)
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Journal Article
The naked mole-rat exhibits an unusual cardiac myofilament protein profile providing new insights into heart function of this naturally subterranean rodent
Grimes, Kelly M., Barefield, David Y., Kumar, Mohit, McNamara, James W., Weintraub, Susan T., de Tombe, Pieter P., Sadayappan, Sakthivel, Buffenstein, Rochelle
Published in Pflügers Archiv (01.12.2017)
Published in Pflügers Archiv (01.12.2017)
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Journal Article
Rpl3l gene deletion in mice reduces heart weight over time
Grimes, Kelly M, Prasad, Vikram, Huo, Jiuzhou, Kuwabara, Yasuhide, Vanhoutte, Davy, Baldwin, Tanya A, Bowers, Stephanie L K, Johansen, Anne Katrine Z, Sargent, Michelle A, Lin, Suh-Chin J, Molkentin, Jeffery D
Published in Frontiers in physiology (17.01.2023)
Published in Frontiers in physiology (17.01.2023)
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Journal Article
Age-related changes in the proteostasis network in the brain of the naked mole-rat: Implications promoting healthy longevity
Triplett, Judy C., Tramutola, Antonella, Swomley, Aaron, Kirk, Jessime, Grimes, Kelly, Lewis, Kaitilyn, Orr, Miranda, Rodriguez, Karl, Cai, Jian, Klein, Jon B., Perluigi, Marzia, Buffenstein, Rochelle, Butterfield, D. Allan
Published in Biochimica et biophysica acta (01.10.2015)
Published in Biochimica et biophysica acta (01.10.2015)
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Journal Article
Getting to the heart of the matter: age-related changes in diastolic heart function in the longest-lived rodent, the naked mole rat
Grimes, Kelly M, Lindsey, Merry L, Gelfond, Jonathan A L, Buffenstein, Rochelle
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (01.04.2012)
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (01.04.2012)
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Journal Article
Reaching Out to Send a Message: Proteins Associated with Neurite Outgrowth and Neurotransmission are Altered with Age in the Long-Lived Naked Mole-Rat
Triplett, Judy C., Swomley, Aaron M., Kirk, Jessime, Grimes, Kelly M., Lewis, Kaitilyn N., Orr, Miranda E., Rodriguez, Karl A., Cai, Jian, Klein, Jon B., Buffenstein, Rochelle, Butterfield, D. Allan
Published in Neurochemical research (01.07.2016)
Published in Neurochemical research (01.07.2016)
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Journal Article