Betrixaban compared with warfarin in patients with atrial fibrillation: results of a phase 2, randomized, dose-ranging study (Explore-Xa)
Connolly, Stuart J, Eikelboom, John, Dorian, Paul, Hohnloser, Stefan H, Gretler, Daniel D, Sinha, Uma, Ezekowitz, Michael D
Published in European heart journal (01.05.2013)
Published in European heart journal (01.05.2013)
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Recommendation of mavacamten posology by model‐based analyses in adults with obstructive hypertrophic cardiomyopathy
Merali, Samira, Salinger, David H., Palmisano, Maria, Sehnert, Amy J., Thanneer, Neelima, Back, Hyunmoon, Seroogy, Julie D., Gretler, Daniel D., Roy, Amit, Perera, Vidya
Published in CPT: pharmacometrics and systems pharmacology (01.09.2024)
Published in CPT: pharmacometrics and systems pharmacology (01.09.2024)
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Characterization of mavacamten pharmacokinetics in patients with hypertrophic cardiomyopathy to inform dose titration
Chang, Peter, Perera, Vidya, Salinger, David H., Merali, Samira, Thanneer, Neelima, Back, Hyunmoon, Seroogy, Julie D., Gretler, Daniel D., Sehnert, Amy J., Palmisano, Maria, Roy, Amit
Published in CPT: pharmacometrics and systems pharmacology (01.09.2024)
Published in CPT: pharmacometrics and systems pharmacology (01.09.2024)
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A randomized evaluation of betrixaban, an oral factor Xa inhibitor, for prevention of thromboembolic events after total knee replacement (EXPERT)
Turpie, Alexander G G, Bauer, Kenneth A, Davidson, Bruce L, Fisher, William D, Gent, Michael, Huo, Michael H, Sinha, Uma, Gretler, Daniel D
Published in Thrombosis and haemostasis (01.01.2009)
Published in Thrombosis and haemostasis (01.01.2009)
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Rationale and design of the randomized, double-blind trial testing INtraveNous and Oral administration of elinogrel, a selective and reversible P2Y12 -receptor inhibitor, versus clopidogrel to eVAluate Tolerability and Efficacy in nonurgent Percutaneous Coronary Interventions patients (INNOVATE-PCI)
Leonardi, Sergio, MD, Rao, Sunil V., MD, Harrington, Robert A., MD, Bhatt, Deepak L., MD, MPH, Gibson, C. Michael, MS, MD, Roe, Matthew T., MD, Kochman, Janusz, MD, PhD, Huber, Kurt, MD, Zeymer, Uwe, MD, Madan, Mina, MD, MHS, Gretler, Daniel D., MD, McClure, Matthew W., MD, Paynter, Gayle E., RN, BS, Thompson, Vivian, MPH, Welsh, Robert C., MD
Published in The American heart journal (01.07.2010)
Published in The American heart journal (01.07.2010)
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Safety and feasibility of adjunctive antiplatelet therapy with intravenous elinogrel, a direct-acting and reversible P2Y12 ADP-receptor antagonist, before primary percutaneous intervention in patients with ST-elevation myocardial infarction: The Early Rapid ReversAl of Platelet ThromboSis with Intravenous Elinogrel before PCI to Optimize REperfusion in Acute Myocardial Infarction (ERASE MI) pilot trial
Berger, Jeffrey S., MD, MS, Roe, Matthew T., MD, MHS, Gibson, C. Michael, MD, MS, Kilaru, Rakhi, MS, Green, Cynthia L., PhD, Melton, Laura, PhD, Blankenship, James D., MD, Metzger, D. Christopher, MD, Granger, Christopher B., MD, Gretler, Daniel D., MD, Grines, Cindy L., MD, Huber, Kurt, MD, Zeymer, Uwe, MD, Buszman, Pawel, MD, Harrington, Robert A., MD, Armstrong, Paul W., MD
Published in The American heart journal (01.12.2009)
Published in The American heart journal (01.12.2009)
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Pharmacokinetics and pharmacodynamics of voxelotor (GBT440) in healthy adults and patients with sickle cell disease
Hutchaleelaha, Athiwat, Patel, Mira, Washington, Carla, Siu, Vincent, Allen, Elizabeth, Oksenberg, Donna, Gretler, Daniel D., Mant, Timothy, Lehrer‐Graiwer, Josh
Published in British journal of clinical pharmacology (01.06.2019)
Published in British journal of clinical pharmacology (01.06.2019)
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A phase 1/2 ascending dose study and open-label extension study of voxelotor in patients with sickle cell disease
Howard, Jo, Hemmaway, Claire Jane, Telfer, Paul, Layton, D. Mark, Porter, John, Awogbade, Moji, Mant, Timothy, Gretler, Daniel D., Dufu, Kobina, Hutchaleelaha, Athiwat, Patel, Mira, Siu, Vincent, Dixon, Sandra, Landsman, Noel, Tonda, Margaret, Lehrer-Graiwer, Joshua
Published in Blood (25.04.2019)
Published in Blood (25.04.2019)
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Drug-Drug Interaction Potential of Mavacamten with Oral Contraceptives: Results from a Clinical Pharmacokinetic Study and a Physiologically Based Pharmacokinetic Model
Chiang, Manting, Sychterz, Caroline, Gaohua, Lu, Perera, Vidya, Gretler, Daniel D, Florea, Victoria, Merali, Samira
Published in Journal of clinical pharmacology (01.11.2023)
Published in Journal of clinical pharmacology (01.11.2023)
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Bridging the gap between clinical trials of antiplatelet therapies and applications among elderly patients
Dauerman, Harold L., MD, Bhatt, Deepak L., MD, MPH, Gretler, Daniel D., MD, French, Patricia A., BS, Smyth, Susan S., MD, PhD, Becker, Richard C., MD
Published in The American heart journal (01.04.2010)
Published in The American heart journal (01.04.2010)
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The Kinetics of Integrilin Limited by Obesity: A multicenter randomized pharmacokinetic and pharmacodynamic clinical trial
Vavalle, John P., MD, Stevens, Susanna R., MS, Hassinger, Nancy, MD, Cohen, Mauricio G., MD, Arnold, Anita, DO, Kandzari, David E., MD, Aguirre, Frank V., MD, Gretler, Daniel D., MD, Alexander, John H., MD, MHS
Published in The American heart journal (01.12.2011)
Published in The American heart journal (01.12.2011)
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Effects of Omeprazole and Verapamil on the Pharmacokinetics, Safety, and Tolerability of Mavacamten: Two Drug–Drug Interaction Studies in Healthy Participants
Perera, Vidya, Gretler, Daniel D., Seroogy, Julie D., Chiang, Manting, Palmisano, Maria, Florea, Victoria
Published in Clinical pharmacology in drug development (01.12.2023)
Published in Clinical pharmacology in drug development (01.12.2023)
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Noninvasive method for determination of arterial compliance using Doppler echocardiography and subclavian pulse tracings : validation and clinical application of a physiological model of the circulation
MARCUS, R. H, KORCARZ, C, SARELI, P, LANG, R. M, MCCRAY, G, NEUMANN, A, MURPHY, M, BOROW, K, WEINERT, L, BEDNARZ, J, GRETLER, D. D, SPENCER, K. T
Published in Circulation (New York, N.Y.) (01.06.1994)
Published in Circulation (New York, N.Y.) (01.06.1994)
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PRT062607 Achieves Complete Inhibition of the Spleen Tyrosine Kinase at Tolerated Exposures Following Oral Dosing in Healthy Volunteers
Coffey, Greg, Rani, Aradhana, Betz, Andreas, Pak, Yvonne, Haberstock‐Debic, Helena, Pandey, Anjali, Hollenbach, Stanley, Gretler, Daniel D., Mant, Tim, Jurcevic, Stipo, Sinha, Uma
Published in Journal of clinical pharmacology (01.02.2017)
Published in Journal of clinical pharmacology (01.02.2017)
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Rationale and design of the randomized, double-blind trial testing INtraveNous and Oral administration of elinogrel, a selective and reversible P2Y(12)-receptor inhibitor, versus clopidogrel to eVAluate Tolerability and Efficacy in nonurgent Percutaneous Coronary Interventions patients (INNOVATE-PCI)
Leonardi, Sergio, Rao, Sunil V, Harrington, Robert A, Bhatt, Deepak L, Gibson, C Michael, Roe, Matthew T, Kochman, Janusz, Huber, Kurt, Zeymer, Uwe, Madan, Mina, Gretler, Daniel D, McClure, Matthew W, Paynter, Gayle E, Thompson, Vivian, Welsh, Robert C
Published in The American heart journal (01.07.2010)
Published in The American heart journal (01.07.2010)
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Ethnic differences in circadian hemodynamic profile
Gretler, D D, Fumo, M T, Nelson, K S, Murphy, M B
Published in American journal of hypertension (01.01.1994)
Published in American journal of hypertension (01.01.1994)
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