Humanized Mouse Models of Clinical Disease
Walsh, Nicole C, Kenney, Laurie L, Jangalwe, Sonal, Aryee, Ken-Edwin, Greiner, Dale L, Brehm, Michael A, Shultz, Leonard D
Published in Annual review of pathology (24.01.2017)
Published in Annual review of pathology (24.01.2017)
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Journal Article
Humanized mice in translational biomedical research
Shultz, Leonard D, Ishikawa, Fumihiko, Greiner, Dale L
Published in Nature Reviews: Immunology (01.02.2007)
Published in Nature Reviews: Immunology (01.02.2007)
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Journal Article
Long-term glycemic control using polymer-encapsulated human stem cell-derived beta cells in immune-competent mice
Vegas, Arturo J, Veiseh, Omid, Gürtler, Mads, Millman, Jeffrey R, Pagliuca, Felicia W, Bader, Andrew R, Doloff, Joshua C, Li, Jie, Chen, Michael, Olejnik, Karsten, Tam, Hok Hei, Jhunjhunwala, Siddharth, Langan, Erin, Aresta-Dasilva, Stephanie, Gandham, Srujan, McGarrigle, James J, Bochenek, Matthew A, Hollister-Lock, Jennifer, Oberholzer, Jose, Greiner, Dale L, Weir, Gordon C, Melton, Douglas A, Langer, Robert, Anderson, Daniel G
Published in Nature medicine (01.03.2016)
Published in Nature medicine (01.03.2016)
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Journal Article
Efficient generation of NKX6-1+ pancreatic progenitors from multiple human pluripotent stem cell lines
Nostro, M Cristina, Sarangi, Farida, Yang, Chaoxing, Holland, Andrew, Elefanty, Andrew G, Stanley, Edouard G, Greiner, Dale L, Keller, Gordon
Published in Stem cell reports (14.04.2015)
Published in Stem cell reports (14.04.2015)
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Journal Article
Humanized mice in studying efficacy and mechanisms of PD‐1‐targeted cancer immunotherapy
Wang, Minan, Yao, Li‐Chin, Cheng, Mingshan, Cai, Danying, Martinek, Jan, Pan, Chong‐Xian, Shi, Wei, Ma, Ai‐Hong, Vere White, Ralph W., Airhart, Susan, Liu, Edison T., Banchereau, Jacques, Brehm, Michael A., Greiner, Dale L., Shultz, Leonard D., Palucka, Karolina, Keck, James G.
Published in The FASEB journal (01.03.2018)
Published in The FASEB journal (01.03.2018)
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Journal Article
Colony stimulating factor-1 receptor is a central component of the foreign body response to biomaterial implants in rodents and non-human primates
Doloff, Joshua C, Veiseh, Omid, Vegas, Arturo J, Tam, Hok Hei, Farah, Shady, Ma, Minglin, Li, Jie, Bader, Andrew, Chiu, Alan, Sadraei, Atieh, Aresta-Dasilva, Stephanie, Griffin, Marissa, Jhunjhunwala, Siddharth, Webber, Matthew, Siebert, Sean, Tang, Katherine, Chen, Michael, Langan, Erin, Dholokia, Nimit, Thakrar, Raj, Qi, Meirigeng, Oberholzer, Jose, Greiner, Dale L, Langer, Robert, Anderson, Daniel G
Published in Nature materials (01.06.2017)
Published in Nature materials (01.06.2017)
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Journal Article
Novel Observations From Next-Generation RNA Sequencing of Highly Purified Human Adult and Fetal Islet Cell Subsets
Blodgett, David M, Nowosielska, Anetta, Afik, Shaked, Pechhold, Susanne, Cura, Anthony J, Kennedy, Norman J, Kim, Soyoung, Kucukural, Alper, Davis, Roger J, Kent, Sally C, Greiner, Dale L, Garber, Manuel G, Harlan, David M, diIorio, Philip
Published in Diabetes (New York, N.Y.) (01.09.2015)
Published in Diabetes (New York, N.Y.) (01.09.2015)
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Journal Article
Long-term implant fibrosis prevention in rodents and non-human primates using crystallized drug formulations
Farah, Shady, Doloff, Joshua C, Müller, Peter, Sadraei, Atieh, Han, Hye Jung, Olafson, Katy, Vyas, Keval, Tam, Hok Hei, Hollister-Lock, Jennifer, Kowalski, Piotr S, Griffin, Marissa, Meng, Ashley, McAvoy, Malia, Graham, Adam C, McGarrigle, James, Oberholzer, Jose, Weir, Gordon C, Greiner, Dale L, Langer, Robert, Anderson, Daniel G
Published in Nature materials (01.08.2019)
Published in Nature materials (01.08.2019)
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Journal Article
Overcoming Current Limitations in Humanized Mouse Research
Brehm, Michael A., Shultz, Leonard D., Luban, Jeremy, Greiner, Dale L.
Published in The Journal of infectious diseases (15.11.2013)
Published in The Journal of infectious diseases (15.11.2013)
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Journal Article
Conference Proceeding
Generation of improved humanized mouse models for human infectious diseases
Brehm, Michael A., Wiles, Michael V., Greiner, Dale L., Shultz, Leonard D.
Published in Journal of immunological methods (01.08.2014)
Published in Journal of immunological methods (01.08.2014)
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Journal Article
Retroviruses use CD169-mediated trans-infection of permissive lymphocytes to establish infection
Sewald, Xaver, Ladinsky, Mark S., Uchil, Pradeep D., Beloor, Jagadish, Pi, Ruoxi, Herrmann, Christin, Motamedi, Nasim, Murrooka, Thomas T., Brehm, Michael A., Greiner, Dale L., Shultz, Leonard D., Mempel, Thorsten R., Bjorkman, Pamela J., Kumar, Priti, Mothes, Walther
Published in Science (American Association for the Advancement of Science) (30.10.2015)
Published in Science (American Association for the Advancement of Science) (30.10.2015)
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Journal Article
The role of JNK in the development of hepatocellular carcinoma
Das, Madhumita, Garlick, David S, Greiner, Dale L, Davis, Roger J
Published in Genes & development (15.03.2011)
Published in Genes & development (15.03.2011)
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Journal Article
AK002, a Humanized Sialic Acid-Binding Immunoglobulin-Like Lectin-8 Antibody that Induces Antibody-Dependent Cell-Mediated Cytotoxicity against Human Eosinophils and Inhibits Mast Cell-Mediated Anaphylaxis in Mice
Youngblood, Bradford A., Brock, Emily C., Leung, John, Falahati, Rustom, Bryce, Paul J., Bright, Jessica, Williams, Jason, Shultz, Leonard D., Greiner, Dale L., Brehm, Michael A., Bebbington, Christopher, Tomasevic, Nenad
Published in International archives of allergy and immunology (01.09.2019)
Published in International archives of allergy and immunology (01.09.2019)
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Journal Article
α Cell Function and Gene Expression Are Compromised in Type 1 Diabetes
Brissova, Marcela, Haliyur, Rachana, Saunders, Diane, Shrestha, Shristi, Dai, Chunhua, Blodgett, David M., Bottino, Rita, Campbell-Thompson, Martha, Aramandla, Radhika, Poffenberger, Gregory, Lindner, Jill, Pan, Fong Cheng, von Herrath, Matthias G., Greiner, Dale L., Shultz, Leonard D., Sanyoura, May, Philipson, Louis H., Atkinson, Mark, Harlan, David M., Levy, Shawn E., Prasad, Nripesh, Stein, Roland, Powers, Alvin C.
Published in Cell reports (Cambridge) (06.03.2018)
Published in Cell reports (Cambridge) (06.03.2018)
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Journal Article
Humanized mouse model of mast cell–mediated passive cutaneous anaphylaxis and passive systemic anaphylaxis
Bryce, Paul J., PhD, Falahati, Rustom, PhD, Kenney, Laurie L., PhD, Leung, John, BS, Bebbington, Christopher, PhD, Tomasevic, Nenad, PhD, Krier, Rebecca A., MS, Hsu, Chia-Lin, PhD, Shultz, Leonard D., PhD, Greiner, Dale L., PhD, Brehm, Michael A., PhD
Published in Journal of allergy and clinical immunology (01.09.2016)
Published in Journal of allergy and clinical immunology (01.09.2016)
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Journal Article
In vivo correction of anaemia in β-thalassemic mice by γPNA-mediated gene editing with nanoparticle delivery
Bahal, Raman, Ali McNeer, Nicole, Quijano, Elias, Liu, Yanfeng, Sulkowski, Parker, Turchick, Audrey, Lu, Yi-Chien, Bhunia, Dinesh C, Manna, Arunava, Greiner, Dale L, Brehm, Michael A, Cheng, Christopher J, López-Giráldez, Francesc, Ricciardi, Adele, Beloor, Jagadish, Krause, Diane S, Kumar, Priti, Gallagher, Patrick G, Braddock, Demetrios T, Mark Saltzman, W, Ly, Danith H, Glazer, Peter M
Published in Nature communications (26.10.2016)
Published in Nature communications (26.10.2016)
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Journal Article
Regulated Splicing of the α6 Integrin Cytoplasmic Domain Determines the Fate of Breast Cancer Stem Cells
Goel, Hira Lal, Gritsko, Tatiana, Pursell, Bryan, Chang, Cheng, Shultz, Leonard D., Greiner, Dale L., Norum, Jens Henrik, Toftgard, Rune, Shaw, Leslie M., Mercurio, Arthur M.
Published in Cell reports (Cambridge) (08.05.2014)
Published in Cell reports (Cambridge) (08.05.2014)
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Journal Article
A laminin 511 matrix is regulated by TAZ and functions as the ligand for the α6Bβ1 integrin to sustain breast cancer stem cells
Chang, Cheng, Goel, Hira Lal, Gao, Huijie, Pursell, Bryan, Shultz, Leonard D, Greiner, Dale L, Ingerpuu, Sulev, Patarroyo, Manuel, Cao, Shiliang, Lim, Elgene, Mao, Junhao, McKee, Karen Kulju, Yurchenco, Peter D, Mercurio, Arthur M
Published in Genes & development (01.01.2015)
Published in Genes & development (01.01.2015)
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Journal Article
T Cell-Specific siRNA Delivery Suppresses HIV-1 Infection in Humanized Mice
Kumar, Priti, Ban, Hong-Seok, Kim, Sang-Soo, Wu, Haoquan, Pearson, Todd, Greiner, Dale L., Laouar, Amale, Yao, Jiahong, Haridas, Viraga, Habiro, Katsuyoshi, Yang, Yong-Guang, Jeong, Ji-Hoon, Lee, Kuen-Yong, Kim, Yong-Hee, Kim, Sung Wan, Peipp, Matthias, Fey, Georg H., Manjunath, N., Shultz, Leonard D., Lee, Sang-Kyung, Shankar, Premlata
Published in Cell (22.08.2008)
Published in Cell (22.08.2008)
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