(ADP-ribosyl)hydrolases: structure, function, and biology
Rack, Johannes Gregor Matthias, Palazzo, Luca, Ahel, Ivan
Published in Genes & development (01.03.2020)
Published in Genes & development (01.03.2020)
Get full text
Journal Article
HPF1/C4orf27 Is a PARP-1-Interacting Protein that Regulates PARP-1 ADP-Ribosylation Activity
Gibbs-Seymour, Ian, Fontana, Pietro, Rack, Johannes Gregor Matthias, Ahel, Ivan
Published in Molecular cell (05.05.2016)
Published in Molecular cell (05.05.2016)
Get full text
Journal Article
Macrodomains: Structure, Function, Evolution, and Catalytic Activities
Rack, Johannes Gregor Matthias, Perina, Dragutin, Ahel, Ivan
Published in Annual review of biochemistry (02.06.2016)
Published in Annual review of biochemistry (02.06.2016)
Get full text
Journal Article
Reversible ADP-ribosylation of RNA
Munnur, Deeksha, Bartlett, Edward, Mikolčević, Petra, Kirby, Ilsa T, Rack, Johannes Gregor Matthias, Mikoč, Andreja, Cohen, Michael S, Ahel, Ivan
Published in Nucleic Acids Research (20.06.2019)
Published in Nucleic Acids Research (20.06.2019)
Get full text
Journal Article
Web Resource
Mechanistic insights into the three steps of poly(ADP-ribosylation) reversal
Rack, Johannes Gregor Matthias, Liu, Qiang, Zorzini, Valentina, Voorneveld, Jim, Ariza, Antonio, Honarmand Ebrahimi, Kourosh, Reber, Julia M., Krassnig, Sarah C., Ahel, Dragana, van der Marel, Gijsbert A., Mangerich, Aswin, McCullagh, James S. O., Filippov, Dmitri V., Ahel, Ivan
Published in Nature communications (28.07.2021)
Published in Nature communications (28.07.2021)
Get full text
Journal Article
Viral macrodomains: a structural and evolutionary assessment of the pharmacological potential
Rack, Johannes Gregor Matthias, Zorzini, Valentina, Zhu, Zihan, Schuller, Marion, Ahel, Dragana, Ahel, Ivan
Published in Open biology (01.11.2020)
Published in Open biology (01.11.2020)
Get full text
Journal Article
Molecular Tools for the Study of ADP‐Ribosylation: A Unified and Versatile Method to Synthesise Native Mono‐ADP‐Ribosylated Peptides
Voorneveld, Jim, Rack, Johannes Gregor Matthias, Gijlswijk, Luke, Meeuwenoord, Nico J., Liu, Qiang, Overkleeft, Herman S., Marel, Gijsbert A., Ahel, Ivan, Filippov, Dmitri V.
Published in Chemistry : a European journal (21.07.2021)
Published in Chemistry : a European journal (21.07.2021)
Get full text
Journal Article
Serine ADP-ribosylation in Drosophila provides insights into the evolution of reversible ADP-ribosylation signalling
Fontana, Pietro, Buch-Larsen, Sara C., Suyari, Osamu, Smith, Rebecca, Suskiewicz, Marcin J., Schützenhofer, Kira, Ariza, Antonio, Rack, Johannes Gregor Matthias, Nielsen, Michael L., Ahel, Ivan
Published in Nature communications (02.06.2023)
Published in Nature communications (02.06.2023)
Get full text
Journal Article
Legionella metaeffector MavL reverses ubiquitin ADP-ribosylation via a conserved arginine-specific macrodomain
Zhang, Zhengrui, Fu, Jiaqi, Rack, Johannes Gregor Matthias, Li, Chuang, Voorneveld, Jim, Filippov, Dmitri V., Ahel, Ivan, Luo, Zhao-Qing, Das, Chittaranjan
Published in Nature communications (19.03.2024)
Published in Nature communications (19.03.2024)
Get full text
Journal Article
Identification of a Class of Protein ADP-Ribosylating Sirtuins in Microbial Pathogens
Rack, Johannes Gregor Matthias, Morra, Rosa, Barkauskaite, Eva, Kraehenbuehl, Rolf, Ariza, Antonio, Qu, Yue, Ortmayer, Mary, Leidecker, Orsolya, Cameron, David R., Matic, Ivan, Peleg, Anton Y., Leys, David, Traven, Ana, Ahel, Ivan
Published in Molecular cell (16.07.2015)
Published in Molecular cell (16.07.2015)
Get full text
Journal Article
The Making and Breaking of Serine-ADP-Ribosylation in the DNA Damage Response
Schützenhofer, Kira, Rack, Johannes Gregor Matthias, Ahel, Ivan
Published in Frontiers in cell and developmental biology (15.11.2021)
Published in Frontiers in cell and developmental biology (15.11.2021)
Get full text
Journal Article
Streptomyces coelicolor macrodomain hydrolase SCO6735 cleaves thymidine-linked ADP-ribosylation of DNA
Hloušek-Kasun, Andrea, Mikolčević, Petra, Rack, Johannes Gregor Matthias, Tromans-Coia, Callum, Schuller, Marion, Jankevicius, Gytis, Matković, Marija, Bertoša, Branimir, Ahel, Ivan, Mikoč, Andreja
Published in Computational and structural biotechnology journal (01.01.2022)
Published in Computational and structural biotechnology journal (01.01.2022)
Get full text
Journal Article
(ADP-ribosyl)hydrolases: Structural Basis for Differential Substrate Recognition and Inhibition
Rack, Johannes Gregor Matthias, Ariza, Antonio, Drown, Bryon S., Henfrey, Callum, Bartlett, Edward, Shirai, Tomohiro, Hergenrother, Paul J., Ahel, Ivan
Published in Cell chemical biology (20.12.2018)
Published in Cell chemical biology (20.12.2018)
Get full text
Journal Article
Noncanonical mono(ADP-ribosyl)ation of zinc finger SZF proteins counteracts ubiquitination for protein homeostasis in plant immunity
Kong, Liang, Feng, Baomin, Yan, Yan, Zhang, Chao, Kim, Jun Hyeok, Xu, Lahong, Rack, Johannes Gregor Matthias, Wang, Ying, Jang, Jyan-Chyun, Ahel, Ivan, Shan, Libo, He, Ping
Published in Molecular cell (18.11.2021)
Published in Molecular cell (18.11.2021)
Get full text
Journal Article
Reversal of tyrosine-linked ADP-ribosylation by ARH3 and PARG
Rack, Johannes Gregor Matthias, Voorneveld, Jim, Longarini, Edoardo José, Wijngaarden, Sven, Zhu, Kang, Peters, Alessandra, Jhing Sia, Jia, Prokhorova, Evgeniia, Ahel, Dragana, Matić, Ivan, Filippov, Dmitri V., Ahel, Ivan
Published in The Journal of biological chemistry (27.09.2024)
Published in The Journal of biological chemistry (27.09.2024)
Get full text
Journal Article
Four of a Kind: A Complete Collection of ADP-Ribosylated Histidine Isosteres Using Cu(I)- and Ru(II)-Catalyzed Click Chemistry
Minnee, Hugo, Chung, Hayley, Rack, Johannes Gregor Matthias, van der Marel, Gijsbert A., Overkleeft, Herman S., Codée, Jeroen D. C., Ahel, Ivan, Filippov, Dmitri V.
Published in Journal of organic chemistry (04.08.2023)
Published in Journal of organic chemistry (04.08.2023)
Get full text
Journal Article
Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking
Schuller, Marion, Correy, Galen J, Gahbauer, Stefan, Fearon, Daren, Wu, Taiasean, Díaz, Roberto Efraín, Young, Iris D, Carvalho Martins, Luan, Smith, Dominique H, Schulze-Gahmen, Ursula, Owens, Tristan W, Deshpande, Ishan, Merz, Gregory E, Thwin, Aye C, Biel, Justin T, Peters, Jessica K, Moritz, Michelle, Herrera, Nadia, Kratochvil, Huong T, Aimon, Anthony, Bennett, James M, Brandao Neto, Jose, Cohen, Aina E, Dias, Alexandre, Douangamath, Alice, Dunnett, Louise, Fedorov, Oleg, Ferla, Matteo P, Fuchs, Martin R, Gorrie-Stone, Tyler J, Holton, James M, Johnson, Michael G, Krojer, Tobias, Meigs, George, Powell, Ailsa J, Rack, Johannes Gregor Matthias, Rangel, Victor L, Russi, Silvia, Skyner, Rachael E, Smith, Clyde A, Soares, Alexei S, Wierman, Jennifer L, Zhu, Kang, O'Brien, Peter, Jura, Natalia, Ashworth, Alan, Irwin, John J, Thompson, Michael C, Gestwicki, Jason E, von Delft, Frank, Shoichet, Brian K, Fraser, James S, Ahel, Ivan
Published in Science advances (01.04.2021)
Published in Science advances (01.04.2021)
Get full text
Journal Article