The convergence of artificial intelligence and chemistry for improved drug discovery
Green, Clive P, Engkvist, Ola, Pairaudeau, Garry
Published in Future medicinal chemistry (01.11.2018)
Published in Future medicinal chemistry (01.11.2018)
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Automated stopped-flow library synthesis for rapid optimisation and machine learning directed experimentation
Avila, Claudio, Cassani, Carlo, Kogej, Thierry, Mazuela, Javier, Sarda, Sunil, Clayton, Adam D, Kossenjans, Michael, Green, Clive P, Bourne, Richard A
Published in Chemical science (Cambridge) (26.10.2022)
Published in Chemical science (Cambridge) (26.10.2022)
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Heat inactivation of clinical COVID-19 samples on an industrial scale for low risk and efficient high-throughput qRT-PCR diagnostic testing
Delpuech, Oona, Douthwaite, Julie A, Hill, Thomas, Niranjan, Dhevahi, Malintan, Nancy T, Duvoisin, Hannah, Elliott, Jane, Goodfellow, Ian, Hosmillo, Myra, Orton, Alexandra L, Taylor, Molly A, Brankin, Christopher, Pitt, Haidee, Ross-Thriepland, Douglas, Siek, Magdalena, Cuthbert, Anna, Richards, Ian, Ferdinand, John R, Barker, Colin, Shaw, Robert, Ariani, Cristina, Waddell, Ian, Rees, Steve, Green, Clive, Clark, Roger, Upadhyay, Abhishek, Howes, Rob
Published in Scientific reports (21.02.2022)
Published in Scientific reports (21.02.2022)
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AZD5438, a potent oral inhibitor of cyclin-dependent kinases 1, 2, and 9, leads to pharmacodynamic changes and potent antitumor effects in human tumor xenografts
Byth, Kate F, Thomas, Andrew, Hughes, Gareth, Forder, Cheryl, McGregor, Alexandra, Geh, Catherine, Oakes, Sandra, Green, Clive, Walker, Mike, Newcombe, Nicholas, Green, Stephen, Growcott, Jim, Barker, Andy, Wilkinson, Robert W
Published in Molecular cancer therapeutics (01.07.2009)
Published in Molecular cancer therapeutics (01.07.2009)
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Identification, optimisation and in vivo evaluation of oxadiazole DGAT-1 inhibitors for the treatment of obesity and diabetes
McCoull, William, Addie, Matthew S., Birch, Alan M., Birtles, Susan, Buckett, Linda K., Butlin, Roger J., Bowker, Suzanne S., Boyd, Scott, Chapman, Stephen, Davies, Robert D.M., Donald, Craig S., Green, Clive P., Jenner, Chloe, Kemmitt, Paul D., Leach, Andrew G., Moody, Graeme C., Morentin Gutierrez, Pablo, Newcombe, Nicholas J., Nowak, Thorsten, Packer, Martin J., Plowright, Alleyn T., Revill, John, Schofield, Paul, Sheldon, Chris, Stokes, Steve, Turnbull, Andrew V., Wang, Steven J.Y., Whalley, David P., Matthew Wood, J.
Published in Bioorganic & medicinal chemistry letters (15.06.2012)
Published in Bioorganic & medicinal chemistry letters (15.06.2012)
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Imidazole pyrimidine amides as potent, orally bioavailable cyclin-dependent kinase inhibitors
Jones, Clifford D., Andrews, David M., Barker, Andrew J., Blades, Kevin, Byth, Kate F., Finlay, M. Raymond V., Geh, Catherine, Green, Clive P., Johannsen, Marie, Walker, Mike, Weir, Hazel M.
Published in Bioorganic & medicinal chemistry (15.12.2008)
Published in Bioorganic & medicinal chemistry (15.12.2008)
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Imidazole piperazines: SAR and development of a potent class of cyclin-dependent kinase inhibitors with a novel binding mode
Finlay, M. Raymond V., Acton, David G., Andrews, David M., Barker, Andrew J., Dennis, Michael, Fisher, Eric, Graham, Mark A., Green, Clive P., Heaton, David W., Karoutchi, Galith, Loddick, Sarah A., Morgentin, Rémy, Roberts, Andrew, Tucker, Julie A., Weir, Hazel M.
Published in Bioorganic & medicinal chemistry (01.08.2008)
Published in Bioorganic & medicinal chemistry (01.08.2008)
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Approaches to the quaternary stereocentre and to the heterocyclic core in diazonamide A using the Heck reaction and related coupling reactions
Booker, James E. M., Boto, Alicia, Churchill, Gwydion H., Green, Clive P., Ling, Matthew, Meek, Graham, Prabhakaran, Jaya, Sinclair, David, Blake, Alexander J., Pattenden, Gerald
Published in Organic & biomolecular chemistry (01.01.2006)
Published in Organic & biomolecular chemistry (01.01.2006)
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Imidazoles: SAR and development of a potent class of cyclin-dependent kinase inhibitors
Anderson, Malcolm, Andrews, David M., Barker, Andy J., Brassington, Claire A., Breed, Jason, Byth, Kate F., Culshaw, Janet D., Finlay, M. Raymond V., Fisher, Eric, McMiken, Helen H.J., Green, Clive P., Heaton, Dave W., Nash, Ian A., Newcombe, Nicholas J., Oakes, Sandra E., Pauptit, Richard A., Roberts, Andrew, Stanway, Judith J., Thomas, Andrew P., Tucker, Julie A., Walker, Mike, Weir, Hazel M.
Published in Bioorganic & medicinal chemistry (15.10.2008)
Published in Bioorganic & medicinal chemistry (15.10.2008)
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Two Possible Nymphaea at Truckle Hill, North Wraxall, Wiltshire
Andrews, Phil, Baker, Darren, Barge, Mel, Green, Clive, Mepham, Lorraine, O'Connell, Jayne, Stone, Mike, Goller, Rob, Craddock, Brenda
Published in Archaeological journal (London) (01.01.2013)
Published in Archaeological journal (London) (01.01.2013)
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Impact of morbid obesity on the mode of delivery and obstetric outcome in nulliparous singleton pregnancy and the implications for rural maternity services
GREEN, Clive, SHAKER, David
Published in Australian & New Zealand journal of obstetrics & gynaecology (01.04.2011)
Published in Australian & New Zealand journal of obstetrics & gynaecology (01.04.2011)
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Why a Special Issue on Acoustic Liquid Handling?
Olechno, Joe, Green, Clive, Rasmussen, Lynn
Published in Journal of Laboratory Automation (01.02.2016)
Published in Journal of Laboratory Automation (01.02.2016)
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Impact of morbid obesity on the mode of delivery and obstetric outcome in nulliparous singleton pregnancy and the implications for rural maternity services: Morbid obesity and pregnancy
GREEN, Clive, SHAKER, David
Published in Australian & New Zealand journal of obstetrics & gynaecology (01.04.2011)
Published in Australian & New Zealand journal of obstetrics & gynaecology (01.04.2011)
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Improving the efficiency and effectiveness of an industrial SARS-CoV-2 diagnostic facility
Douthwaite, Julie A, Brown, Christopher A, Ferdinand, John R, Sharma, Rahul, Elliott, Jane, Taylor, Molly A, Malintan, Nancy T, Duvoisin, Hannah, Hill, Thomas, Delpuech, Oona, Orton, Alexandra L, Pitt, Haidee, Kuenzi, Fred, Fish, Simon, Nicholls, David J, Cuthbert, Anna, Richards, Ian, Ratcliffe, Giles, Upadhyay, Abhishek, Marklew, Abigail, Hewitt, Craig, Ross-Thriepland, Douglas, Brankin, Christopher, Chodorge, Matthieu, Browne, Gareth, Mander, Palwinder K, DeWildt, Ruud M, Weaver, Shane, Smee, Penny A, van Kempen, Joost, Bartlett, Jon G, Allen, Paula M, Koppe, Emma L, Ashby, Charlotte A, Phipps, Julian D, Mehta, Nalini, Brierley, David J, Tew, David G, Leveridge, Melanie V, Baddeley, Stuart M, Goodfellow, Ian G, Green, Clive, Abell, Chris, Neely, Andy, Waddell, Ian, Rees, Steve, Maxwell, Patrick H, Pangalos, Menelas N, Howes, Rob, Clark, Roger
Published in Scientific reports (24.02.2022)
Published in Scientific reports (24.02.2022)
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The Experts Speak on Biobank Education
O'Donoghue, Sheila, Byrne, Jennifer A, Green, Clive, Hill, Kristina, Kozlakidis, Zisis, De Wilde, Annemieke, Mullins, Piper, Wiles, Kerry R
Published in Biopreservation and biobanking (01.02.2020)
Published in Biopreservation and biobanking (01.02.2020)
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Identification, Optimization, and Pharmacology of Acylurea GHS-R1a Inverse Agonists
McCoull, William, Barton, Peter, Brown, Alastair J. H, Bowker, Suzanne S, Cameron, Jennifer, Clarke, David S, Davies, Robert D. M, Dossetter, Alexander G, Ertan, Anne, Fenwick, Mark, Green, Clive, Holmes, Jane L, Martin, Nathaniel, Masters, David, Moore, Jane E, Newcombe, Nicholas J, Newton, Claire, Pointon, Helen, Robb, Graeme R, Sheldon, Christopher, Stokes, Stephen, Morgan, David
Published in Journal of medicinal chemistry (24.07.2014)
Published in Journal of medicinal chemistry (24.07.2014)
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Alkynes to ( E)-enolates using tandem catalysis: stereoselective anti-aldol and syn-[3,3]-rearrangement reactions
Grimster, Neil P., Wilton, Donna A.A., Chan, Louis K.M., Godfrey, Christopher R.A., Green, Clive, Owen, Dafydd R., Gaunt, Matthew J.
Published in Tetrahedron (14.08.2010)
Published in Tetrahedron (14.08.2010)
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Alkynes to (E)-enolates using tandem catalysis: stereoselective anti-aldol and syn-[3,3]-rearrangement reactions: 2009 Tetrahedron Prize for Creativity in Organic Chemistry: Adventures in Organic Synthesis: Steven V. Ley
GRIMSTER, Neil P, WILTON, Donna A. A, CHAN, Louis K. M, GODFREY, Christopher R. A, GREEN, Clive, OWEN, Dafydd R, GAUNT, Matthew J
Published in Tetrahedron (2010)
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Published in Tetrahedron (2010)
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